Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs Transcription factors Other IDs Associated diseases
Entrez ID	5770
Gene name	Protein tyrosine phosphatase non-receptor type 1
Gene symbol	PTPN1
Synonyms (NCBI Gene)	PTP1B
Chromosome	20
Chromosome location	20q13.13
Summary	The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters s

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SNP ID	Visualize variation	Clinical significance	Consequence
rs16989673	->G	Risk-factor	3 prime UTR variant

714

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miRTarBase ID	miRNA	Experiments	Reference
MIRT003154	hsa-miR-210-3p	2DGEimmunoprecipitaionLuciferase reporter assayMass spectrometryMicroarrayqRT-PCRWestern blot	19826008
MIRT007007	hsa-miR-122-5p	Luciferase reporter assay	22807119
MIRT007351	hsa-miR-362-3p	Western blot	23280316
MIRT007351	hsa-miR-362-3p	Western blot	23280316
MIRT007351	hsa-miR-362-3p	Western blot	23280316
MIRT007351	hsa-miR-362-3p	Western blot	23280316
MIRT019939	hsa-miR-375	Microarray	20215506
MIRT023987	hsa-miR-1-3p	Proteomics	18668040
MIRT029981	hsa-miR-26b-5p	Microarray	19088304
MIRT756270	hsa-miR-135a-5p	Luciferase reporter assayWestern blottingqRT-PCR	35610725
MIRT756299	hsa-miR-125a-5p	Luciferase reporter assayImmunofluorescence	35401562
MIRT1274644	hsa-miR-1	CLIP-seq
MIRT1274645	hsa-miR-1179	CLIP-seq
MIRT1274646	hsa-miR-1185	CLIP-seq
MIRT1274647	hsa-miR-1206	CLIP-seq
MIRT1274648	hsa-miR-122	CLIP-seq
MIRT1274649	hsa-miR-1226	CLIP-seq
MIRT1274650	hsa-miR-1229	CLIP-seq
MIRT1274651	hsa-miR-1236	CLIP-seq
MIRT1274652	hsa-miR-1246	CLIP-seq
MIRT1274653	hsa-miR-1257	CLIP-seq
MIRT1274654	hsa-miR-1273g	CLIP-seq
MIRT1274655	hsa-miR-129-3p	CLIP-seq
MIRT1274656	hsa-miR-1294	CLIP-seq
MIRT1274657	hsa-miR-130a	CLIP-seq
MIRT1274658	hsa-miR-130b	CLIP-seq
MIRT1274659	hsa-miR-1321	CLIP-seq
MIRT1274660	hsa-miR-135a	CLIP-seq
MIRT1274661	hsa-miR-135b	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT1274665	hsa-miR-185	CLIP-seq
MIRT1274666	hsa-miR-1908	CLIP-seq
MIRT1274667	hsa-miR-198	CLIP-seq
MIRT1274668	hsa-miR-203	CLIP-seq
MIRT1274669	hsa-miR-206	CLIP-seq
MIRT1274670	hsa-miR-2110	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274674	hsa-miR-224	CLIP-seq
MIRT1274675	hsa-miR-2467-3p	CLIP-seq
MIRT1274676	hsa-miR-28-3p	CLIP-seq
MIRT1274677	hsa-miR-2861	CLIP-seq
MIRT1274678	hsa-miR-298	CLIP-seq
MIRT1274679	hsa-miR-299-5p	CLIP-seq
MIRT1274680	hsa-miR-301a	CLIP-seq
MIRT1274681	hsa-miR-301b	CLIP-seq
MIRT1274682	hsa-miR-3120-3p	CLIP-seq
MIRT1274683	hsa-miR-3146	CLIP-seq
MIRT1274684	hsa-miR-3148	CLIP-seq
MIRT1274685	hsa-miR-3150a-3p	CLIP-seq
MIRT1274686	hsa-miR-3161	CLIP-seq
MIRT1274687	hsa-miR-3180	CLIP-seq
MIRT1274688	hsa-miR-3180-3p	CLIP-seq
MIRT1274689	hsa-miR-3180-5p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274691	hsa-miR-3184	CLIP-seq
MIRT1274692	hsa-miR-3187-3p	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT1274694	hsa-miR-3196	CLIP-seq
MIRT1274695	hsa-miR-323-3p	CLIP-seq
MIRT1274696	hsa-miR-329	CLIP-seq
MIRT1274697	hsa-miR-338-3p	CLIP-seq
MIRT1274698	hsa-miR-338-5p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274700	hsa-miR-34c-3p	CLIP-seq
MIRT1274701	hsa-miR-3591-5p	CLIP-seq
MIRT1274702	hsa-miR-3605-5p	CLIP-seq
MIRT1274703	hsa-miR-3613-3p	CLIP-seq
MIRT1274704	hsa-miR-3614-3p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT1274706	hsa-miR-3661	CLIP-seq
MIRT1274707	hsa-miR-3665	CLIP-seq
MIRT1274708	hsa-miR-3666	CLIP-seq
MIRT1274709	hsa-miR-3667-5p	CLIP-seq
MIRT1274710	hsa-miR-3673	CLIP-seq
MIRT1274711	hsa-miR-3679-5p	CLIP-seq
MIRT1274712	hsa-miR-370	CLIP-seq
MIRT1274713	hsa-miR-371b-5p	CLIP-seq
MIRT1274714	hsa-miR-374c	CLIP-seq
MIRT1274715	hsa-miR-380	CLIP-seq
MIRT1274716	hsa-miR-3913-3p	CLIP-seq
MIRT1274717	hsa-miR-3914	CLIP-seq
MIRT1274718	hsa-miR-3929	CLIP-seq
MIRT1274719	hsa-miR-3941	CLIP-seq
MIRT1274720	hsa-miR-423-5p	CLIP-seq
MIRT1274721	hsa-miR-4260	CLIP-seq
MIRT1274722	hsa-miR-4266	CLIP-seq
MIRT1274723	hsa-miR-4267	CLIP-seq
MIRT1274724	hsa-miR-4270	CLIP-seq
MIRT1274725	hsa-miR-4271	CLIP-seq
MIRT1274726	hsa-miR-4273	CLIP-seq
MIRT1274727	hsa-miR-4279	CLIP-seq
MIRT1274728	hsa-miR-4282	CLIP-seq
MIRT1274729	hsa-miR-4291	CLIP-seq
MIRT1274730	hsa-miR-4295	CLIP-seq
MIRT1274731	hsa-miR-4297	CLIP-seq
MIRT1274732	hsa-miR-4306	CLIP-seq
MIRT1274733	hsa-miR-4417	CLIP-seq
MIRT1274734	hsa-miR-4419b	CLIP-seq
MIRT1274735	hsa-miR-4424	CLIP-seq
MIRT1274736	hsa-miR-4426	CLIP-seq
MIRT1274737	hsa-miR-4436a	CLIP-seq
MIRT1274738	hsa-miR-4437	CLIP-seq
MIRT1274739	hsa-miR-4438	CLIP-seq
MIRT1274740	hsa-miR-4441	CLIP-seq
MIRT1274741	hsa-miR-4447	CLIP-seq
MIRT1274742	hsa-miR-4461	CLIP-seq
MIRT1274743	hsa-miR-4470	CLIP-seq
MIRT1274744	hsa-miR-4472	CLIP-seq
MIRT1274745	hsa-miR-4473	CLIP-seq
MIRT1274746	hsa-miR-4477a	CLIP-seq
MIRT1274747	hsa-miR-4478	CLIP-seq
MIRT1274748	hsa-miR-4488	CLIP-seq
MIRT1274749	hsa-miR-4502	CLIP-seq
MIRT1274750	hsa-miR-4505	CLIP-seq
MIRT1274751	hsa-miR-4519	CLIP-seq
MIRT1274752	hsa-miR-451b	CLIP-seq
MIRT1274753	hsa-miR-4528	CLIP-seq
MIRT1274754	hsa-miR-4529-5p	CLIP-seq
MIRT1274755	hsa-miR-4530	CLIP-seq
MIRT1274756	hsa-miR-454	CLIP-seq
MIRT1274757	hsa-miR-4639-3p	CLIP-seq
MIRT1274758	hsa-miR-4641	CLIP-seq
MIRT1274759	hsa-miR-4644	CLIP-seq
MIRT1274760	hsa-miR-4647	CLIP-seq
MIRT1274761	hsa-miR-4662b	CLIP-seq
MIRT1274762	hsa-miR-4668-5p	CLIP-seq
MIRT1274763	hsa-miR-4671-3p	CLIP-seq
MIRT1274764	hsa-miR-4674	CLIP-seq
MIRT1274765	hsa-miR-4677-5p	CLIP-seq
MIRT1274766	hsa-miR-4682	CLIP-seq
MIRT1274767	hsa-miR-4687-3p	CLIP-seq
MIRT1274768	hsa-miR-4690-5p	CLIP-seq
MIRT1274769	hsa-miR-4695-5p	CLIP-seq
MIRT1274770	hsa-miR-4696	CLIP-seq
MIRT1274771	hsa-miR-4697-5p	CLIP-seq
MIRT1274772	hsa-miR-4700-3p	CLIP-seq
MIRT1274773	hsa-miR-4708-3p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274775	hsa-miR-4718	CLIP-seq
MIRT1274776	hsa-miR-4720-3p	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT1274778	hsa-miR-4723-5p	CLIP-seq
MIRT1274779	hsa-miR-4725-3p	CLIP-seq
MIRT1274780	hsa-miR-4725-5p	CLIP-seq
MIRT1274781	hsa-miR-4733-3p	CLIP-seq
MIRT1274782	hsa-miR-4733-5p	CLIP-seq
MIRT1274783	hsa-miR-4734	CLIP-seq
MIRT1274784	hsa-miR-4739	CLIP-seq
MIRT1274785	hsa-miR-4752	CLIP-seq
MIRT1274786	hsa-miR-4753-3p	CLIP-seq
MIRT1274787	hsa-miR-4755-3p	CLIP-seq
MIRT1274788	hsa-miR-4756-3p	CLIP-seq
MIRT1274789	hsa-miR-4756-5p	CLIP-seq
MIRT1274790	hsa-miR-4767	CLIP-seq
MIRT1274791	hsa-miR-4779	CLIP-seq
MIRT1274792	hsa-miR-4780	CLIP-seq
MIRT1274793	hsa-miR-4789-5p	CLIP-seq
MIRT1274794	hsa-miR-4795-3p	CLIP-seq
MIRT1274795	hsa-miR-489	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT1274797	hsa-miR-504	CLIP-seq
MIRT1274798	hsa-miR-515-5p	CLIP-seq
MIRT1274799	hsa-miR-520a-5p	CLIP-seq
MIRT1274800	hsa-miR-520g	CLIP-seq
MIRT1274801	hsa-miR-520h	CLIP-seq
MIRT1274802	hsa-miR-525-5p	CLIP-seq
MIRT1274803	hsa-miR-532-5p	CLIP-seq
MIRT1274804	hsa-miR-544b	CLIP-seq
MIRT1274805	hsa-miR-545	CLIP-seq
MIRT1274806	hsa-miR-548ac	CLIP-seq
MIRT1274807	hsa-miR-548ae	CLIP-seq
MIRT1274808	hsa-miR-548aj	CLIP-seq
MIRT1274809	hsa-miR-548am	CLIP-seq
MIRT1274810	hsa-miR-548d-3p	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT1274813	hsa-miR-548x	CLIP-seq
MIRT1274814	hsa-miR-548z	CLIP-seq
MIRT1274815	hsa-miR-561	CLIP-seq
MIRT1274816	hsa-miR-580	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274818	hsa-miR-590-3p	CLIP-seq
MIRT1274819	hsa-miR-595	CLIP-seq
MIRT1274820	hsa-miR-603	CLIP-seq
MIRT1274821	hsa-miR-606	CLIP-seq
MIRT1274822	hsa-miR-613	CLIP-seq
MIRT1274823	hsa-miR-617	CLIP-seq
MIRT1274824	hsa-miR-629	CLIP-seq
MIRT1274825	hsa-miR-631	CLIP-seq
MIRT1274826	hsa-miR-654-3p	CLIP-seq
MIRT1274827	hsa-miR-655	CLIP-seq
MIRT1274828	hsa-miR-656	CLIP-seq
MIRT1274829	hsa-miR-659	CLIP-seq
MIRT1274830	hsa-miR-662	CLIP-seq
MIRT1274831	hsa-miR-663	CLIP-seq
MIRT1274832	hsa-miR-760	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274834	hsa-miR-764	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT1274837	hsa-miR-939	CLIP-seq
MIRT1274838	hsa-miR-942	CLIP-seq
MIRT1274644	hsa-miR-1	CLIP-seq
MIRT2080797	hsa-miR-105	CLIP-seq
MIRT2080798	hsa-miR-1197	CLIP-seq
MIRT1274648	hsa-miR-122	CLIP-seq
MIRT2080799	hsa-miR-1228	CLIP-seq
MIRT1274650	hsa-miR-1229	CLIP-seq
MIRT1274651	hsa-miR-1236	CLIP-seq
MIRT1274653	hsa-miR-1257	CLIP-seq
MIRT2080800	hsa-miR-1260	CLIP-seq
MIRT2080801	hsa-miR-1260b	CLIP-seq
MIRT2080802	hsa-miR-1268	CLIP-seq
MIRT2080803	hsa-miR-1268b	CLIP-seq
MIRT2080804	hsa-miR-1269	CLIP-seq
MIRT2080805	hsa-miR-1269b	CLIP-seq
MIRT2080806	hsa-miR-1273c	CLIP-seq
MIRT1274654	hsa-miR-1273g	CLIP-seq
MIRT2080807	hsa-miR-1278	CLIP-seq
MIRT1274656	hsa-miR-1294	CLIP-seq
MIRT1274657	hsa-miR-130a	CLIP-seq
MIRT1274658	hsa-miR-130b	CLIP-seq
MIRT1274660	hsa-miR-135a	CLIP-seq
MIRT1274661	hsa-miR-135b	CLIP-seq
MIRT2080808	hsa-miR-137	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT2080809	hsa-miR-188-3p	CLIP-seq
MIRT2080810	hsa-miR-193a-3p	CLIP-seq
MIRT2080811	hsa-miR-193b	CLIP-seq
MIRT1274668	hsa-miR-203	CLIP-seq
MIRT1274669	hsa-miR-206	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274675	hsa-miR-2467-3p	CLIP-seq
MIRT1274676	hsa-miR-28-3p	CLIP-seq
MIRT1274680	hsa-miR-301a	CLIP-seq
MIRT1274681	hsa-miR-301b	CLIP-seq
MIRT2080812	hsa-miR-3130-3p	CLIP-seq
MIRT2080813	hsa-miR-3156-3p	CLIP-seq
MIRT1274689	hsa-miR-3180-5p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT1274696	hsa-miR-329	CLIP-seq
MIRT1274697	hsa-miR-338-3p	CLIP-seq
MIRT1274698	hsa-miR-338-5p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274700	hsa-miR-34c-3p	CLIP-seq
MIRT1274701	hsa-miR-3591-5p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT2080814	hsa-miR-3663-5p	CLIP-seq
MIRT1274707	hsa-miR-3665	CLIP-seq
MIRT1274708	hsa-miR-3666	CLIP-seq
MIRT2080815	hsa-miR-3667-3p	CLIP-seq
MIRT1274709	hsa-miR-3667-5p	CLIP-seq
MIRT1274710	hsa-miR-3673	CLIP-seq
MIRT2080816	hsa-miR-3675-5p	CLIP-seq
MIRT1274714	hsa-miR-374c	CLIP-seq
MIRT1274719	hsa-miR-3941	CLIP-seq
MIRT1274722	hsa-miR-4266	CLIP-seq
MIRT1274725	hsa-miR-4271	CLIP-seq
MIRT1274726	hsa-miR-4273	CLIP-seq
MIRT1274730	hsa-miR-4295	CLIP-seq
MIRT1274733	hsa-miR-4417	CLIP-seq
MIRT2080817	hsa-miR-4423-3p	CLIP-seq
MIRT1274735	hsa-miR-4424	CLIP-seq
MIRT1274736	hsa-miR-4426	CLIP-seq
MIRT1274737	hsa-miR-4436a	CLIP-seq
MIRT1274738	hsa-miR-4437	CLIP-seq
MIRT1274745	hsa-miR-4473	CLIP-seq
MIRT1274746	hsa-miR-4477a	CLIP-seq
MIRT2080818	hsa-miR-4514	CLIP-seq
MIRT1274752	hsa-miR-451b	CLIP-seq
MIRT2080819	hsa-miR-4520a-3p	CLIP-seq
MIRT2080820	hsa-miR-4520b-3p	CLIP-seq
MIRT2080821	hsa-miR-4527	CLIP-seq
MIRT2080822	hsa-miR-4529-3p	CLIP-seq
MIRT1274755	hsa-miR-4530	CLIP-seq
MIRT1274756	hsa-miR-454	CLIP-seq
MIRT1274760	hsa-miR-4647	CLIP-seq
MIRT1274761	hsa-miR-4662b	CLIP-seq
MIRT2080823	hsa-miR-4663	CLIP-seq
MIRT2080824	hsa-miR-4666-5p	CLIP-seq
MIRT1274763	hsa-miR-4671-3p	CLIP-seq
MIRT1274764	hsa-miR-4674	CLIP-seq
MIRT1274765	hsa-miR-4677-5p	CLIP-seq
MIRT1274766	hsa-miR-4682	CLIP-seq
MIRT2080825	hsa-miR-4684-5p	CLIP-seq
MIRT2080826	hsa-miR-4692	CLIP-seq
MIRT1274769	hsa-miR-4695-5p	CLIP-seq
MIRT1274770	hsa-miR-4696	CLIP-seq
MIRT1274772	hsa-miR-4700-3p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT1274778	hsa-miR-4723-5p	CLIP-seq
MIRT1274779	hsa-miR-4725-3p	CLIP-seq
MIRT1274780	hsa-miR-4725-5p	CLIP-seq
MIRT2080827	hsa-miR-4731-3p	CLIP-seq
MIRT1274783	hsa-miR-4734	CLIP-seq
MIRT2080828	hsa-miR-4736	CLIP-seq
MIRT2080829	hsa-miR-4750	CLIP-seq
MIRT1274788	hsa-miR-4756-3p	CLIP-seq
MIRT1274790	hsa-miR-4767	CLIP-seq
MIRT2080830	hsa-miR-4768-5p	CLIP-seq
MIRT1274791	hsa-miR-4779	CLIP-seq
MIRT1274793	hsa-miR-4789-5p	CLIP-seq
MIRT2080831	hsa-miR-4801	CLIP-seq
MIRT2080832	hsa-miR-4803	CLIP-seq
MIRT2080833	hsa-miR-486-3p	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT1274797	hsa-miR-504	CLIP-seq
MIRT1274800	hsa-miR-520g	CLIP-seq
MIRT1274801	hsa-miR-520h	CLIP-seq
MIRT2080834	hsa-miR-548a-3p	CLIP-seq
MIRT1274806	hsa-miR-548ac	CLIP-seq
MIRT1274807	hsa-miR-548ae	CLIP-seq
MIRT1274808	hsa-miR-548aj	CLIP-seq
MIRT1274809	hsa-miR-548am	CLIP-seq
MIRT1274810	hsa-miR-548d-3p	CLIP-seq
MIRT2080835	hsa-miR-548e	CLIP-seq
MIRT2080836	hsa-miR-548f	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT1274813	hsa-miR-548x	CLIP-seq
MIRT1274814	hsa-miR-548z	CLIP-seq
MIRT1274815	hsa-miR-561	CLIP-seq
MIRT2080837	hsa-miR-576-5p	CLIP-seq
MIRT2080838	hsa-miR-586	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274819	hsa-miR-595	CLIP-seq
MIRT2080839	hsa-miR-600	CLIP-seq
MIRT2080840	hsa-miR-602	CLIP-seq
MIRT1274820	hsa-miR-603	CLIP-seq
MIRT1274821	hsa-miR-606	CLIP-seq
MIRT1274822	hsa-miR-613	CLIP-seq
MIRT1274823	hsa-miR-617	CLIP-seq
MIRT2080841	hsa-miR-628-5p	CLIP-seq
MIRT1274824	hsa-miR-629	CLIP-seq
MIRT1274826	hsa-miR-654-3p	CLIP-seq
MIRT1274827	hsa-miR-655	CLIP-seq
MIRT2080842	hsa-miR-657	CLIP-seq
MIRT1274832	hsa-miR-760	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274834	hsa-miR-764	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT2080843	hsa-miR-767-3p	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT2080844	hsa-miR-890	CLIP-seq
MIRT2080845	hsa-miR-892b	CLIP-seq
MIRT2080846	hsa-miR-940	CLIP-seq
MIRT1274838	hsa-miR-942	CLIP-seq
MIRT1274644	hsa-miR-1	CLIP-seq
MIRT1274645	hsa-miR-1179	CLIP-seq
MIRT1274646	hsa-miR-1185	CLIP-seq
MIRT2080798	hsa-miR-1197	CLIP-seq
MIRT1274647	hsa-miR-1206	CLIP-seq
MIRT1274649	hsa-miR-1226	CLIP-seq
MIRT1274650	hsa-miR-1229	CLIP-seq
MIRT2306834	hsa-miR-124	CLIP-seq
MIRT1274652	hsa-miR-1246	CLIP-seq
MIRT1274653	hsa-miR-1257	CLIP-seq
MIRT2306835	hsa-miR-1263	CLIP-seq
MIRT2080804	hsa-miR-1269	CLIP-seq
MIRT2080805	hsa-miR-1269b	CLIP-seq
MIRT2080806	hsa-miR-1273c	CLIP-seq
MIRT2080807	hsa-miR-1278	CLIP-seq
MIRT2306836	hsa-miR-1286	CLIP-seq
MIRT2306837	hsa-miR-1290	CLIP-seq
MIRT1274655	hsa-miR-129-3p	CLIP-seq
MIRT1274656	hsa-miR-1294	CLIP-seq
MIRT1274657	hsa-miR-130a	CLIP-seq
MIRT1274658	hsa-miR-130b	CLIP-seq
MIRT1274659	hsa-miR-1321	CLIP-seq
MIRT1274660	hsa-miR-135a	CLIP-seq
MIRT1274661	hsa-miR-135b	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT1274665	hsa-miR-185	CLIP-seq
MIRT1274666	hsa-miR-1908	CLIP-seq
MIRT2306838	hsa-miR-194	CLIP-seq
MIRT1274667	hsa-miR-198	CLIP-seq
MIRT1274668	hsa-miR-203	CLIP-seq
MIRT2306839	hsa-miR-204	CLIP-seq
MIRT1274669	hsa-miR-206	CLIP-seq
MIRT2306840	hsa-miR-211	CLIP-seq
MIRT2306841	hsa-miR-2115	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274674	hsa-miR-224	CLIP-seq
MIRT1274675	hsa-miR-2467-3p	CLIP-seq
MIRT1274677	hsa-miR-2861	CLIP-seq
MIRT2306842	hsa-miR-29a	CLIP-seq
MIRT2306843	hsa-miR-29b	CLIP-seq
MIRT2306844	hsa-miR-29c	CLIP-seq
MIRT1274680	hsa-miR-301a	CLIP-seq
MIRT1274681	hsa-miR-301b	CLIP-seq
MIRT2306845	hsa-miR-3121-5p	CLIP-seq
MIRT1274683	hsa-miR-3146	CLIP-seq
MIRT2306846	hsa-miR-3158-5p	CLIP-seq
MIRT1274686	hsa-miR-3161	CLIP-seq
MIRT2306847	hsa-miR-3167	CLIP-seq
MIRT2306848	hsa-miR-3179	CLIP-seq
MIRT1274687	hsa-miR-3180	CLIP-seq
MIRT1274688	hsa-miR-3180-3p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274692	hsa-miR-3187-3p	CLIP-seq
MIRT2306849	hsa-miR-3190	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT1274694	hsa-miR-3196	CLIP-seq
MIRT2306850	hsa-miR-3202	CLIP-seq
MIRT1274695	hsa-miR-323-3p	CLIP-seq
MIRT1274696	hsa-miR-329	CLIP-seq
MIRT1274698	hsa-miR-338-5p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274700	hsa-miR-34c-3p	CLIP-seq
MIRT1274702	hsa-miR-3605-5p	CLIP-seq
MIRT1274704	hsa-miR-3614-3p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT2306851	hsa-miR-3657	CLIP-seq
MIRT1274706	hsa-miR-3661	CLIP-seq
MIRT2306852	hsa-miR-3663-3p	CLIP-seq
MIRT2080814	hsa-miR-3663-5p	CLIP-seq
MIRT1274708	hsa-miR-3666	CLIP-seq
MIRT2080815	hsa-miR-3667-3p	CLIP-seq
MIRT1274710	hsa-miR-3673	CLIP-seq
MIRT2080816	hsa-miR-3675-5p	CLIP-seq
MIRT1274711	hsa-miR-3679-5p	CLIP-seq
MIRT2306853	hsa-miR-3691-5p	CLIP-seq
MIRT2306854	hsa-miR-3714	CLIP-seq
MIRT1274714	hsa-miR-374c	CLIP-seq
MIRT1274715	hsa-miR-380	CLIP-seq
MIRT2306855	hsa-miR-383	CLIP-seq
MIRT2306856	hsa-miR-3910	CLIP-seq
MIRT1274717	hsa-miR-3914	CLIP-seq
MIRT1274719	hsa-miR-3941	CLIP-seq
MIRT1274722	hsa-miR-4266	CLIP-seq
MIRT1274724	hsa-miR-4270	CLIP-seq
MIRT1274726	hsa-miR-4273	CLIP-seq
MIRT1274728	hsa-miR-4282	CLIP-seq
MIRT1274729	hsa-miR-4291	CLIP-seq
MIRT1274730	hsa-miR-4295	CLIP-seq
MIRT1274731	hsa-miR-4297	CLIP-seq
MIRT1274732	hsa-miR-4306	CLIP-seq
MIRT2080817	hsa-miR-4423-3p	CLIP-seq
MIRT1274737	hsa-miR-4436a	CLIP-seq
MIRT1274739	hsa-miR-4438	CLIP-seq
MIRT1274740	hsa-miR-4441	CLIP-seq
MIRT1274742	hsa-miR-4461	CLIP-seq
MIRT1274743	hsa-miR-4470	CLIP-seq
MIRT1274746	hsa-miR-4477a	CLIP-seq
MIRT1274748	hsa-miR-4488	CLIP-seq
MIRT1274749	hsa-miR-4502	CLIP-seq
MIRT1274750	hsa-miR-4505	CLIP-seq
MIRT2080818	hsa-miR-4514	CLIP-seq
MIRT1274751	hsa-miR-4519	CLIP-seq
MIRT2080819	hsa-miR-4520a-3p	CLIP-seq
MIRT2080820	hsa-miR-4520b-3p	CLIP-seq
MIRT2080821	hsa-miR-4527	CLIP-seq
MIRT1274753	hsa-miR-4528	CLIP-seq
MIRT2080822	hsa-miR-4529-3p	CLIP-seq
MIRT1274754	hsa-miR-4529-5p	CLIP-seq
MIRT2306857	hsa-miR-4533	CLIP-seq
MIRT1274756	hsa-miR-454	CLIP-seq
MIRT1274758	hsa-miR-4641	CLIP-seq
MIRT1274759	hsa-miR-4644	CLIP-seq
MIRT2080824	hsa-miR-4666-5p	CLIP-seq
MIRT1274763	hsa-miR-4671-3p	CLIP-seq
MIRT1274765	hsa-miR-4677-5p	CLIP-seq
MIRT2306858	hsa-miR-4688	CLIP-seq
MIRT1274768	hsa-miR-4690-5p	CLIP-seq
MIRT2080826	hsa-miR-4692	CLIP-seq
MIRT1274769	hsa-miR-4695-5p	CLIP-seq
MIRT1274771	hsa-miR-4697-5p	CLIP-seq
MIRT1274772	hsa-miR-4700-3p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274776	hsa-miR-4720-3p	CLIP-seq
MIRT2306859	hsa-miR-4722-5p	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT1274778	hsa-miR-4723-5p	CLIP-seq
MIRT2080827	hsa-miR-4731-3p	CLIP-seq
MIRT1274781	hsa-miR-4733-3p	CLIP-seq
MIRT1274783	hsa-miR-4734	CLIP-seq
MIRT2080828	hsa-miR-4736	CLIP-seq
MIRT1274784	hsa-miR-4739	CLIP-seq
MIRT1274785	hsa-miR-4752	CLIP-seq
MIRT1274787	hsa-miR-4755-3p	CLIP-seq
MIRT2306860	hsa-miR-4755-5p	CLIP-seq
MIRT1274788	hsa-miR-4756-3p	CLIP-seq
MIRT1274789	hsa-miR-4756-5p	CLIP-seq
MIRT2306861	hsa-miR-4761-5p	CLIP-seq
MIRT1274790	hsa-miR-4767	CLIP-seq
MIRT2306862	hsa-miR-4772-5p	CLIP-seq
MIRT1274791	hsa-miR-4779	CLIP-seq
MIRT1274792	hsa-miR-4780	CLIP-seq
MIRT1274794	hsa-miR-4795-3p	CLIP-seq
MIRT2306863	hsa-miR-4796-3p	CLIP-seq
MIRT2080831	hsa-miR-4801	CLIP-seq
MIRT2080832	hsa-miR-4803	CLIP-seq
MIRT2080833	hsa-miR-486-3p	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT2306864	hsa-miR-506	CLIP-seq
MIRT2306865	hsa-miR-516a-3p	CLIP-seq
MIRT1274799	hsa-miR-520a-5p	CLIP-seq
MIRT1274800	hsa-miR-520g	CLIP-seq
MIRT1274801	hsa-miR-520h	CLIP-seq
MIRT1274802	hsa-miR-525-5p	CLIP-seq
MIRT1274804	hsa-miR-544b	CLIP-seq
MIRT1274805	hsa-miR-545	CLIP-seq
MIRT2080834	hsa-miR-548a-3p	CLIP-seq
MIRT2080835	hsa-miR-548e	CLIP-seq
MIRT2080836	hsa-miR-548f	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT2306866	hsa-miR-548n	CLIP-seq
MIRT1274815	hsa-miR-561	CLIP-seq
MIRT2080837	hsa-miR-576-5p	CLIP-seq
MIRT1274816	hsa-miR-580	CLIP-seq
MIRT2080838	hsa-miR-586	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274818	hsa-miR-590-3p	CLIP-seq
MIRT2080840	hsa-miR-602	CLIP-seq
MIRT1274820	hsa-miR-603	CLIP-seq
MIRT1274821	hsa-miR-606	CLIP-seq
MIRT1274822	hsa-miR-613	CLIP-seq
MIRT1274823	hsa-miR-617	CLIP-seq
MIRT2306867	hsa-miR-623	CLIP-seq
MIRT2306868	hsa-miR-624	CLIP-seq
MIRT1274825	hsa-miR-631	CLIP-seq
MIRT1274827	hsa-miR-655	CLIP-seq
MIRT1274828	hsa-miR-656	CLIP-seq
MIRT2080842	hsa-miR-657	CLIP-seq
MIRT1274829	hsa-miR-659	CLIP-seq
MIRT1274830	hsa-miR-662	CLIP-seq
MIRT1274831	hsa-miR-663	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT2306869	hsa-miR-767-5p	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT2306870	hsa-miR-876-5p	CLIP-seq
MIRT2306871	hsa-miR-888	CLIP-seq
MIRT2080844	hsa-miR-890	CLIP-seq
MIRT1274837	hsa-miR-939	CLIP-seq
MIRT2080846	hsa-miR-940	CLIP-seq
MIRT1274838	hsa-miR-942	CLIP-seq
MIRT1274668	hsa-miR-203	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274696	hsa-miR-329	CLIP-seq
MIRT1274698	hsa-miR-338-5p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274714	hsa-miR-374c	CLIP-seq
MIRT1274719	hsa-miR-3941	CLIP-seq
MIRT1274722	hsa-miR-4266	CLIP-seq
MIRT1274769	hsa-miR-4695-5p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274791	hsa-miR-4779	CLIP-seq
MIRT1274793	hsa-miR-4789-5p	CLIP-seq
MIRT2080833	hsa-miR-486-3p	CLIP-seq
MIRT1274798	hsa-miR-515-5p	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT1274820	hsa-miR-603	CLIP-seq
MIRT1274821	hsa-miR-606	CLIP-seq
MIRT1274827	hsa-miR-655	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT2080844	hsa-miR-890	CLIP-seq
MIRT2080802	hsa-miR-1268	CLIP-seq
MIRT2080803	hsa-miR-1268b	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT1274675	hsa-miR-2467-3p	CLIP-seq
MIRT1274676	hsa-miR-28-3p	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT2439707	hsa-miR-4304	CLIP-seq
MIRT1274733	hsa-miR-4417	CLIP-seq
MIRT1274737	hsa-miR-4436a	CLIP-seq
MIRT1274738	hsa-miR-4437	CLIP-seq
MIRT1274764	hsa-miR-4674	CLIP-seq
MIRT2080825	hsa-miR-4684-5p	CLIP-seq
MIRT1274774	hsa-miR-4712-5p	CLIP-seq
MIRT1274783	hsa-miR-4734	CLIP-seq
MIRT2080829	hsa-miR-4750	CLIP-seq
MIRT2439708	hsa-miR-4763-5p	CLIP-seq
MIRT1274790	hsa-miR-4767	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274832	hsa-miR-760	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT1274836	hsa-miR-770-5p	CLIP-seq
MIRT2439709	hsa-miR-938	CLIP-seq
MIRT2306836	hsa-miR-1286	CLIP-seq
MIRT2306842	hsa-miR-29a	CLIP-seq
MIRT2306843	hsa-miR-29b	CLIP-seq
MIRT2306844	hsa-miR-29c	CLIP-seq
MIRT2306852	hsa-miR-3663-3p	CLIP-seq
MIRT1274772	hsa-miR-4700-3p	CLIP-seq
MIRT2306859	hsa-miR-4722-5p	CLIP-seq
MIRT2306869	hsa-miR-767-5p	CLIP-seq
MIRT2604526	hsa-miR-1184	CLIP-seq
MIRT2604527	hsa-miR-1205	CLIP-seq
MIRT2604528	hsa-miR-1224-3p	CLIP-seq
MIRT2080799	hsa-miR-1228	CLIP-seq
MIRT1274651	hsa-miR-1236	CLIP-seq
MIRT2080800	hsa-miR-1260	CLIP-seq
MIRT2080801	hsa-miR-1260b	CLIP-seq
MIRT1274654	hsa-miR-1273g	CLIP-seq
MIRT2604529	hsa-miR-1280	CLIP-seq
MIRT1274659	hsa-miR-1321	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT1274663	hsa-miR-146a	CLIP-seq
MIRT1274664	hsa-miR-146b-5p	CLIP-seq
MIRT2080809	hsa-miR-188-3p	CLIP-seq
MIRT2604530	hsa-miR-1909	CLIP-seq
MIRT2080810	hsa-miR-193a-3p	CLIP-seq
MIRT2080811	hsa-miR-193b	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT1274672	hsa-miR-216a	CLIP-seq
MIRT1274673	hsa-miR-216b	CLIP-seq
MIRT1274676	hsa-miR-28-3p	CLIP-seq
MIRT2604531	hsa-miR-31	CLIP-seq
MIRT2604532	hsa-miR-3128	CLIP-seq
MIRT2080813	hsa-miR-3156-3p	CLIP-seq
MIRT2306846	hsa-miR-3158-5p	CLIP-seq
MIRT1274689	hsa-miR-3180-5p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274693	hsa-miR-3194-3p	CLIP-seq
MIRT1274697	hsa-miR-338-3p	CLIP-seq
MIRT1274699	hsa-miR-342-3p	CLIP-seq
MIRT1274704	hsa-miR-3614-3p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT2604533	hsa-miR-3647-3p	CLIP-seq
MIRT1274707	hsa-miR-3665	CLIP-seq
MIRT1274724	hsa-miR-4270	CLIP-seq
MIRT1274731	hsa-miR-4297	CLIP-seq
MIRT1274740	hsa-miR-4441	CLIP-seq
MIRT1274743	hsa-miR-4470	CLIP-seq
MIRT2080821	hsa-miR-4527	CLIP-seq
MIRT1274755	hsa-miR-4530	CLIP-seq
MIRT1274758	hsa-miR-4641	CLIP-seq
MIRT1274767	hsa-miR-4687-3p	CLIP-seq
MIRT1274768	hsa-miR-4690-5p	CLIP-seq
MIRT2604534	hsa-miR-4698	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT1274784	hsa-miR-4739	CLIP-seq
MIRT1274789	hsa-miR-4756-5p	CLIP-seq
MIRT2080830	hsa-miR-4768-5p	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT2604535	hsa-miR-548an	CLIP-seq
MIRT1274811	hsa-miR-548h	CLIP-seq
MIRT1274812	hsa-miR-548j	CLIP-seq
MIRT1274817	hsa-miR-589	CLIP-seq
MIRT1274819	hsa-miR-595	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274834	hsa-miR-764	CLIP-seq
MIRT1274835	hsa-miR-765	CLIP-seq
MIRT2080843	hsa-miR-767-3p	CLIP-seq
MIRT2080845	hsa-miR-892b	CLIP-seq
MIRT1274644	hsa-miR-1	CLIP-seq
MIRT2604528	hsa-miR-1224-3p	CLIP-seq
MIRT2080799	hsa-miR-1228	CLIP-seq
MIRT1274651	hsa-miR-1236	CLIP-seq
MIRT2080800	hsa-miR-1260	CLIP-seq
MIRT2080801	hsa-miR-1260b	CLIP-seq
MIRT1274654	hsa-miR-1273g	CLIP-seq
MIRT2604529	hsa-miR-1280	CLIP-seq
MIRT1274662	hsa-miR-140-3p	CLIP-seq
MIRT2080809	hsa-miR-188-3p	CLIP-seq
MIRT2080810	hsa-miR-193a-3p	CLIP-seq
MIRT2080811	hsa-miR-193b	CLIP-seq
MIRT1274669	hsa-miR-206	CLIP-seq
MIRT1274671	hsa-miR-214	CLIP-seq
MIRT2604531	hsa-miR-31	CLIP-seq
MIRT2604532	hsa-miR-3128	CLIP-seq
MIRT2080813	hsa-miR-3156-3p	CLIP-seq
MIRT1274689	hsa-miR-3180-5p	CLIP-seq
MIRT1274690	hsa-miR-3183	CLIP-seq
MIRT1274697	hsa-miR-338-3p	CLIP-seq
MIRT1274705	hsa-miR-3619-5p	CLIP-seq
MIRT2604533	hsa-miR-3647-3p	CLIP-seq
MIRT2689060	hsa-miR-3659	CLIP-seq
MIRT1274707	hsa-miR-3665	CLIP-seq
MIRT1274710	hsa-miR-3673	CLIP-seq
MIRT1274718	hsa-miR-3929	CLIP-seq
MIRT2689061	hsa-miR-4300	CLIP-seq
MIRT1274734	hsa-miR-4419b	CLIP-seq
MIRT1274747	hsa-miR-4478	CLIP-seq
MIRT2080821	hsa-miR-4527	CLIP-seq
MIRT1274755	hsa-miR-4530	CLIP-seq
MIRT2689062	hsa-miR-4633-3p	CLIP-seq
MIRT1274767	hsa-miR-4687-3p	CLIP-seq
MIRT2604534	hsa-miR-4698	CLIP-seq
MIRT1274777	hsa-miR-4723-3p	CLIP-seq
MIRT2689063	hsa-miR-4730	CLIP-seq
MIRT1274782	hsa-miR-4733-5p	CLIP-seq
MIRT2080830	hsa-miR-4768-5p	CLIP-seq
MIRT2689064	hsa-miR-485-5p	CLIP-seq
MIRT1274796	hsa-miR-498	CLIP-seq
MIRT2604535	hsa-miR-548an	CLIP-seq
MIRT1274819	hsa-miR-595	CLIP-seq
MIRT1274822	hsa-miR-613	CLIP-seq
MIRT2689065	hsa-miR-658	CLIP-seq
MIRT1274833	hsa-miR-761	CLIP-seq
MIRT1274834	hsa-miR-764	CLIP-seq
MIRT2080843	hsa-miR-767-3p	CLIP-seq
MIRT2080844	hsa-miR-890	CLIP-seq
MIRT2080845	hsa-miR-892b	CLIP-seq
MIRT2689066	hsa-miR-920	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
AR	Unknown	22282656

103

Show/Hide all (103)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003084	Process	Positive regulation of systemic arterial blood pressure	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0004721	Function	Phosphoprotein phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	IDA	18074158, 21707536, 22169477
GO:0004725	Function	Protein tyrosine phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	TAS
GO:0004726	Function	Non-membrane spanning protein tyrosine phosphatase activity	IBA
GO:0005158	Function	Insulin receptor binding	IEA
GO:0005515	Function	Protein binding	IPI	8702689, 8940134, 8999839, 9050838, 9355745, 9407132, 9418872, 9566916, 9600099, 10660596, 10889023, 11007774, 11106648, 11163213, 11506178, 11579209, 11694501, 11970898, 12023880, 12176037, 12237455, 12614164, 12634852, 12857726, 12907755, 14527337, 14722096, 15588987, 15821101, 158
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005759	Component	Mitochondrial matrix	IEA
GO:0005769	Component	Early endosome	IBA
GO:0005769	Component	Early endosome	IDA	21135139
GO:0005769	Component	Early endosome	IEA
GO:0005769	Component	Early endosome	ISS
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	21135139
GO:0006470	Process	Protein dephosphorylation	IMP	22045810
GO:0008270	Function	Zinc ion binding	IDA	18074158
GO:0008285	Process	Negative regulation of cell population proliferation	IEA
GO:0008286	Process	Insulin receptor signaling pathway	IEA
GO:0009966	Process	Regulation of signal transduction	IMP	21135139
GO:0009968	Process	Negative regulation of signal transduction	TAS
GO:0010460	Process	Positive regulation of heart rate	IEA
GO:0010666	Process	Positive regulation of cardiac muscle cell apoptotic process	IEA
GO:0010812	Process	Negative regulation of cell-substrate adhesion	IEA
GO:0010977	Process	Negative regulation of neuron projection development	IEA
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0016791	Function	Phosphatase activity	IEA
GO:0019899	Function	Enzyme binding	IPI	22169477
GO:0019901	Function	Protein kinase binding	IBA
GO:0019901	Function	Protein kinase binding	IPI	22169477
GO:0030036	Process	Actin cytoskeleton organization	IMP	21135139
GO:0030061	Component	Mitochondrial crista	IEA
GO:0030100	Process	Regulation of endocytosis	IDA	21135139
GO:0030162	Process	Regulation of proteolysis	IEA
GO:0030948	Process	Negative regulation of vascular endothelial growth factor receptor signaling pathway	IEA
GO:0030948	Process	Negative regulation of vascular endothelial growth factor receptor signaling pathway	ISS
GO:0030968	Process	Endoplasmic reticulum unfolded protein response	IDA	22169477
GO:0030971	Function	Receptor tyrosine kinase binding	IEA
GO:0030971	Function	Receptor tyrosine kinase binding	IPI	18819921
GO:0031667	Process	Response to nutrient levels	IEA
GO:0031904	Component	Endosome lumen	IEA
GO:0032869	Process	Cellular response to insulin stimulus	IEA
GO:0032991	Component	Protein-containing complex	IDA	28246125
GO:0033157	Process	Regulation of intracellular protein transport	IMP	22045810
GO:0034620	Process	Cellular response to unfolded protein	TAS	22013210
GO:0034976	Process	Response to endoplasmic reticulum stress	IEA
GO:0035335	Process	Peptidyl-tyrosine dephosphorylation	IDA	21135139
GO:0035335	Process	Peptidyl-tyrosine dephosphorylation	IMP	14966296
GO:0035791	Process	Platelet-derived growth factor receptor-beta signaling pathway	IEA
GO:0035791	Process	Platelet-derived growth factor receptor-beta signaling pathway	IMP	14966296
GO:0036120	Process	Cellular response to platelet-derived growth factor stimulus	IEA
GO:0036498	Process	IRE1-mediated unfolded protein response	IEA
GO:0036498	Process	IRE1-mediated unfolded protein response	ISS
GO:0038020	Process	Insulin receptor recycling	IEA
GO:0043407	Process	Negative regulation of MAP kinase activity	IMP	22045810
GO:0044344	Process	Cellular response to fibroblast growth factor stimulus	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0046330	Process	Positive regulation of JNK cascade	IEA
GO:0046330	Process	Positive regulation of JNK cascade	ISS
GO:0046626	Process	Regulation of insulin receptor signaling pathway	IEA
GO:0046627	Process	Negative regulation of insulin receptor signaling pathway	NAS	11742412
GO:0046875	Function	Ephrin receptor binding	IPI	21135139
GO:0051721	Function	Protein phosphatase 2A binding	IEA
GO:0051898	Process	Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA
GO:0060338	Process	Regulation of type I interferon-mediated signaling pathway	IEA
GO:0060338	Process	Regulation of type I interferon-mediated signaling pathway	TAS
GO:0060397	Process	Growth hormone receptor signaling pathway via JAK-STAT	TAS
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IBA
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IEA
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	ISS
GO:0071456	Process	Cellular response to hypoxia	IEA
GO:0071732	Process	Cellular response to nitric oxide	IEA
GO:0097443	Component	Sorting endosome	IEA
GO:0097443	Component	Sorting endosome	ISS
GO:0097706	Process	Vascular endothelial cell response to oscillatory fluid shear stress	TAS
GO:0098554	Component	Cytoplasmic side of endoplasmic reticulum membrane	IDA	1739967
GO:0098794	Component	Postsynapse	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0150052	Process	Regulation of postsynapse assembly	IEA
GO:1902202	Process	Regulation of hepatocyte growth factor receptor signaling pathway	IEA
GO:1902202	Process	Regulation of hepatocyte growth factor receptor signaling pathway	IMP	18819921
GO:1902236	Process	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	IEA
GO:1902236	Process	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	ISS
GO:1903896	Process	Positive regulation of IRE1-mediated unfolded protein response	TAS	22013210
GO:1903898	Process	Negative regulation of PERK-mediated unfolded protein response	IBA
GO:1903898	Process	Negative regulation of PERK-mediated unfolded protein response	IDA	21216966
GO:1903898	Process	Negative regulation of PERK-mediated unfolded protein response	IEA
GO:1904385	Process	Cellular response to angiotensin	IEA
GO:1904753	Process	Negative regulation of vascular associated smooth muscle cell migration	IEA
GO:1990090	Process	Cellular response to nerve growth factor stimulus	IEA
GO:1990776	Process	Response to angiotensin	IEA
GO:2000353	Process	Positive regulation of endothelial cell apoptotic process	IEA
GO:2000646	Process	Positive regulation of receptor catabolic process	IMP	22045810

MIM	HGNC	e!Ensembl
176885	9642	ENSG00000196396

P18031

Protein name

Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)

Protein function

Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII-

PDB

1A5Y , 1AAX , 1BZC , 1BZH , 1BZJ , 1C83 , 1C84 , 1C85 , 1C86 , 1C87 , 1C88 , 1ECV , 1EEN , 1EEO , 1G1F , 1G1G , 1G1H , 1G7F , 1G7G , 1GFY , 1I57 , 1JF7 , 1KAK , 1KAV , 1L8G , 1LQF , 1NL9 , 1NNY , 1NO6 , 1NWE , 1NWL , 1NZ7 , 1OEM , 1OEO , 1OES , 1OET , 1OEU , 1OEV , 1ONY , 1ONZ , 1PA1 , 1PH0 , 1PTT , 1PTU , 1PTV , 1PTY , 1PXH , 1PYN , 1Q1M , 1Q6J , 1Q6M

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00102	Y_phosphatase	40 → 276	Protein-tyrosine phosphatase	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in keratinocytes (at protein level). {ECO:0000269|PubMed:29043977}.

Sequence

MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLH
QEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLK
CAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWP
DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKD
PSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLE
PPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYG
IESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLT
AGAYLCYRFLFNSNT

Sequence length

435

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (23)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
AUTOINFLAMMATORY SYNDROME	—	Disgenet, GenCC Disgenet, GenCC	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC ISCHEMIC HEART DISEASE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERIOSCLEROSIS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY HEART DISEASE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETES MELLITUS, NON-INSULIN-DEPENDENT	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETES MELLITUS, TYPE 2	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DUCHENNE MUSCULAR DYSTROPHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESSENTIAL HYPERTENSION	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HODGKIN DISEASE	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERINSULINISM	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSIVE DISEASE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSULIN RESISTANCE	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Insulin resistance, susceptibility to	risk factor	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LYMPHOMA, B-CELL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL ISCHEMIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PTPN1-related disorder	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RETT SYNDROME	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VITILIGO	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (177)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Abetalipoproteinemia	Abetalipoproteinemia	BEFREE	9566916		★★★★★ ★☆☆☆☆ Found in Text Mining only
Acute leukemia	Leukemia	BEFREE	29122767		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Hodgkin Lymphoma	Hodgkin Lymphoma	BEFREE	24531327		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Hodgkin Lymphoma	Hodgkin Lymphoma	CTD_human_DG	24531327		★★★★★ ★☆☆☆☆ Found in Text Mining only
Amnesia	Amnesia	BEFREE	28965984		★★★★★ ★☆☆☆☆ Found in Text Mining only
Androgenetic Alopecia	Androgenetic Alopecia	BEFREE	30195058		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anemia Aplastic	Aplastic anemia	Pubtator	39179703	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Anxiety Disorders	Anxiety Disorder	BEFREE	28403933		★★★★★ ★☆☆☆☆ Found in Text Mining only
Aortic Valve Stenosis	Aortic Valve Sclerosis	BEFREE	29929988		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	16505227, 28752048, 28899902		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	16505227, 28752048, 28899902		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	24590766		★★★★★ ★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	24531327, 26817397		★★★★★ ★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	CTD_human_DG	24531327		★★★★★ ★☆☆☆☆ Found in Text Mining only
Behcet Syndrome	Behcet disease	Pubtator	28166214, 29907633	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Blast Phase	Blast phase chronic myelogenous leukemia	BEFREE	9826659		★★★★★ ★☆☆☆☆ Found in Text Mining only
Blood Coagulation Disorders	Blood coagulation disorder	Pubtator	25042561	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Ischemia	Cerebral Ischemia	BEFREE	29705606		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	11007774, 18183590, 18332219, 19435911, 20059965, 21630024, 21849469, 23358729, 24845231, 27323329, 27465552, 28378571, 28492548, 28551626, 28870898 View all (7 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	11007774, 18183590, 18332219, 19435911, 20952588, 23242616, 25590580, 27465552, 28378571, 28492548, 29183848, 36871762	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	25590580, 38014992	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	26755347, 36618415	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	36741874	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	31262859		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	21632985, 36618415	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Basal Cell	Carcinoma	BEFREE	19012732		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	12417041		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	BEFREE	27596049, 28752048, 28899902, 29894845, 31319588		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	23590304, 26813343		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Ulcerative colitis	Pubtator	35484353	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	17974954, 24465712		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic Neoplasms	LHGDN	17974954		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic Neoplasms	BEFREE	27855221		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	23280316, 23990346, 27752061		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	26942883	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Compensatory Hyperinsulinemia	Compensatory Hyperinsulinemia	CTD_human_DG	28899902		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Heart Defects	Congenital heart defects	BEFREE	28941626		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	BEFREE	27596049, 29894845, 29929988		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	BEFREE	21676396		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Disease	Coronary artery disease	Pubtator	15189365	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Restenosis	Coronary restenosis	Pubtator	35968900	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn disease	Pubtator	28166214	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn disease	Pubtator	28729389	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	20131294, 31781260		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dementia, Vascular	Dementia	BEFREE	30721761		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	10665340, 11836311, 12472377, 16198645, 16505227, 18387954, 23374726, 23640882, 24625984, 24845231, 27752061, 27871946, 27872190, 28173704, 28212750 View all (23 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Complications	Diabetes complications	Pubtator	15189365	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Gestational	Gestational diabetes	Pubtator	35449053	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	10665340, 11836311, 12472377, 16198645, 16505227, 18387954, 18925540, 23374726, 23640882, 24625984, 24845231, 27752061, 27871946, 27872190, 28173704 View all (28 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	11163213, 15189365, 15229188, 15715684, 21962515, 22688339, 28212750, 29348454, 30875760, 33400373, 36649358	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	15189365, 15715684, 15866871, 15919835, 16407290, 16677372, 17674807, 24865376, 30729132	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	22474028	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	BEFREE	25974252, 29154192		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	10066387, 10665340, 11703427, 11756316, 12209150, 12554649, 15189365, 15504984, 15919813, 16677372, 17286230, 17333110, 17634210, 18054739, 18077048 View all (61 more)		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	CTD_human_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	HPO_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diabetic Foot	Diabetic foot	Pubtator	22688339	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Neuropathies	Diabetic Nephropathy	BEFREE	29526716		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Retinopathy	Diabetic Retinopathy	BEFREE	18077048		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diffuse Large B-Cell Lymphoma	Diffuse Lymphoma	BEFREE	15591113, 18716132, 31331250		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dyslipidemias	Dyslipidemias	BEFREE	15235769, 20101100, 29852391, 30974944		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dyslipidemias	Dyslipidemias	Pubtator	16677372	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dystrophia myotonica 2	Myotonic dystrophy	BEFREE	15715684		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endogenous Hyperinsulinism	Endogenous Hyperinsulinism	CTD_human_DG	28899902		★★★★★ ★☆☆☆☆ Found in Text Mining only
Essential Hypertension	Hypertension	BEFREE	15229188		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Essential Hypertension	Hypertension	Pubtator	15229188	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Exogenous Hyperinsulinism	Exogenous Hyperinsulinism	CTD_human_DG	28899902		★★★★★ ★☆☆☆☆ Found in Text Mining only
Familial lichen amyloidosis	Lichen amyloidosis	BEFREE	29769704		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fatty Liver	Fatty Liver	BEFREE	29351427		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fatty Liver Disease	Fatty Liver	BEFREE	29126873		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fibrosis, Liver	Liver Fibrosis	BEFREE	31299613, 31711802		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Gastrointestinal stromal tumor	BEFREE	30804049		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Gastrointestinal stromal tumor	Pubtator	30804049	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	21972092		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	38014992	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	21972092		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	12883693, 31015365, 31173266		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	16319070	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	BEFREE	27596049, 29894845, 29929988		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hemangioma	Hemangioma	BEFREE	28569147		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	31774495	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	21144060, 28082443, 29650799, 32079702, 33382412, 36723991	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hodgkin Disease	Hodgkin Disease	BEFREE	24531327		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hodgkin Disease	Hodgkin Disease	CTD_human_DG	24531327		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hodgkin lymphoma, lymphocyte depletion	Hodgkin Lymphoma, Lymphocyte Depletion	CTD_human_DG	24531327		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	BEFREE	28025059, 28987240, 30625317, 31322002		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperinsulinism	Hyperinsulinism	BEFREE	10066387, 25974252, 29027136, 31309546, 31743023		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hyperinsulinism	Hyperinsulinism	CTD_human_DG	28899902		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypertension	Hypertension	Pubtator	15189365, 15229188	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypertensive disease	Hypertension	BEFREE	15189365, 20101100, 21188419		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypertensive disease	Hypertension	CTD_human_DG	28899902		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Immunologic Deficiency Syndromes	Immunologic Deficiency Syndromes	BEFREE	17974954		★★★★★ ★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	28988132		★★★★★ ★☆☆☆☆ Found in Text Mining only
Insulin Resistance	Diabetes mellitus, type 2	Pubtator	11136729, 11833006, 15229188, 17908551, 26193288, 26402673, 35449053, 36649358	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Insulin Resistance	Diabetes mellitus, type 2	Pubtator	27516476	Stimulate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Intracranial Aneurysm	Intracranial aneurysm	Pubtator	36451838	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney disease	Pubtator	36618415	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leprosy	Leprosy	Pubtator	28166214	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	26817397		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	36618415	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	21513978, 29122767		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	14976221, 26299811, 26755347, 26840794, 31048362, 31527306		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Failure	Liver failure	BEFREE	23661004		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Failure	Liver failure	Pubtator	23867504	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	BEFREE	14976221		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung diseases	Lung Diseases	BEFREE	23590304, 26813343		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	27465552, 33469269	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	28378571	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphocyte Rich Classical Hodgkin Lymphoma	Classical Hodgkin lymphoma	CTD_human_DG	24531327		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	22890838, 26817397		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	35806064	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	11007774, 18183590, 18332219, 19435911, 19635455, 20059965, 21630024, 21849469, 23358729, 24845231, 27323329, 27465552, 28378571, 28492548, 28551626 View all (8 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	31262859		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	12417041		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	24123012, 31745071		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	16652382, 22282656, 25590580, 27020859		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	20388125, 21442314, 25590580, 29743567, 31441000		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	12554649, 16198645, 18387954, 19091943, 21442314, 23814047, 23879520, 23990346, 28212750, 28318895, 28492548, 28569147, 29122767, 29216799, 29441120 View all (11 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	17974954, 24465712		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of mediastinum	Malignant Mediastinal Neoplasm	CTD_human_DG	24531327		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	18332219		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	19635455, 21849469, 31695578		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mediastinal Neoplasms	Mediastinal Neoplasms	CTD_human_DG	24531327		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	31532203		★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Diseases	Metabolic Diseases	BEFREE	16677372, 23879520, 25263014, 25974252, 26989693, 27596049		★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Diseases	Metabolic Diseases	LHGDN	16677372		★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome	Metabolic syndrome	Pubtator	15229188, 15866871	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	BEFREE	15235769, 16249458, 17560463, 21079391, 23879520, 29186763		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mitochondrial Diseases	Mitochondrial disease	Pubtator	36649358	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mixed Cellularity Hodgkin Lymphoma	Classical Hodgkin lymphoma	CTD_human_DG	24531327		★★★★★ ★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy, Duchenne	Duchenne Muscular Dystrophy	GWASCAT_DG	30014611		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myeloid Leukemia, Chronic	Myeloid Leukemia	BEFREE	21795709, 9566916, 9826659		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	29569957, 31425379		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	10815905, 17974954, 21849469, 23879520, 23990346, 24465712, 26840794, 27020859, 27323329, 27855221, 28038441, 28378571, 28492548, 28551626, 29122767 View all (8 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	28359145, 31837707		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	31837707	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	28359145, 29235148, 31491569		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nodular Lymphocyte Predominant Hodgkin Lymphoma	Classical Hodgkin lymphoma	CTD_human_DG	24531327		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	26580981, 29126873		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	30223019		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nonalcoholic Steatohepatitis	Non-alcoholic Fatty Liver Disease	BEFREE	29126873		★★★★★ ★☆☆☆☆ Found in Text Mining only
Noonan Syndrome	Noonan Syndrome	LHGDN	17056636		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	10665340, 11703427, 15229188, 15235769, 16677372, 17333110, 17560463, 18054739, 18846048, 20101100, 21188419, 21605081, 23374726, 23640882, 23879520 View all (37 more)		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Obesity	Obesity	CTD_human_DG	10744717, 20075852		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Obesity	Obesity	Pubtator	11163213, 15229188, 15866871, 16407290, 16677372, 17674807, 18846048, 21962515, 24865376, 28492548, 29348454, 30729132, 33400373, 33782530, 36369476, 9218523 View all (1 more)	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Oestrogen receptor positive breast cancer	Oestrogen Receptor Positive Breast Cancer	BEFREE	27465552		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	32851074	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	12417041		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	23814047, 29920310, 39179931	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	24123012, 31745071		★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	Lymphoblastic Leukemia	BEFREE	26817397		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	16652382, 22282656, 27020859		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	LHGDN	16652382		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	BEFREE	22282656		★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	BEFREE	27976820		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	38162988	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Rett Syndrome	Rett Syndrome	CTD_human_DG	26214522		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	BEFREE	17849003, 27976820		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	PSYGENET_DG	17849003		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Septicemia	Septicemia	BEFREE	28272165		★★★★★ ★☆☆☆☆ Found in Text Mining only
Somatotropin deficiency	Somatotropin Deficiency	BEFREE	23761422, 27651465		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	23814025, 28287835, 31735331		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	19430297	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Steatohepatitis	Fatty Liver	BEFREE	28673968, 29351427		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	20388125, 21442314, 25590580, 29743567, 31441000		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Diseases	Stomach disease	Pubtator	25590580	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	25590580, 35661947	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
synovial sarcoma	Synovial sarcoma	BEFREE	23580575		★★★★★ ★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasm	Thyroid Neoplasm	BEFREE	27855221		★★★★★ ★☆☆☆☆ Found in Text Mining only
Trigeminal Neuralgia	Trigeminal neuralgia	Pubtator	38158702	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	39819723	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Turner Syndrome	Turner Syndrome	BEFREE	23761422, 27651465		★★★★★ ★☆☆☆☆ Found in Text Mining only
Turner Syndrome	Turner syndrome	Pubtator	23761422, 27651465	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	24459064	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	33469269	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uveal melanoma	Uveal melanoma	Pubtator	36618415	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Vascular Diseases	Vascular Diseases	BEFREE	28569147		★★★★★ ★☆☆☆☆ Found in Text Mining only

PTPN1 (protein tyrosine phosphatase non-receptor type 1)