PSPC1 (paraspeckle component 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 55269 |
| Gene name | Paraspeckle component 1 |
| Gene symbol | PSPC1 |
| Synonyms (NCBI Gene) |
PSP1
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| Chromosome | 13 |
| Chromosome location | 13q12.11 |
| Summary | This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8WXF1 | ||||||||||||||||||||
| Protein name | Paraspeckle component 1 (Paraspeckle protein 1) | ||||||||||||||||||||
| Protein function | RNA-binding protein required for the formation of nuclear paraspeckles (PubMed:22416126). Binds to poly(A), poly(G) and poly(U) RNA homopolymers (PubMed:22416126). Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene tran | ||||||||||||||||||||
| PDB | 3SDE , 5IFN , 5WPA | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart. {ECO:0000269|PubMed:11790299}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 523 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Related Genes
Genes most often co-reported with PSPC1 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to PSPC1 (see Related Genes above), that are NOT already directly curated for PSPC1 itself -- a lead worth checking, not a confirmed association.
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