PRSS58 (serine protease 58)

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Gene Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 136541
• Gene name: Serine protease 58
• Gene symbol: PRSS58
• Synonyms (NCBI Gene): PRSS1, TRY1, TRYX3, UNQ2540
• Chromosome: 7
• Chromosome location: 7q34
• Summary: This gene encodes a member of the trypsin family of serine proteases. This gene and several related trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. This gene was previously described as a trypsinogen-like pseudogene, but

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004252	Function	Serine-type endopeptidase activity	IBA
GO:0004252	Function	Serine-type endopeptidase activity	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IBA
GO:0006508	Process	Proteolysis	IEA
GO:0008233	Function	Peptidase activity	IEA
GO:0008236	Function	Serine-type peptidase activity	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0030141	Component	Secretory granule	IBA
GO:0030141	Component	Secretory granule	IEA
GO:0051604	Process	Protein maturation	IBA
GO:2000243	Process	Positive regulation of reproductive process	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8IYP2
• Protein name: Serine protease 58 (EC 3.4.21.4) (Trypsin-X3)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00089	Trypsin	20 → 234	Trypsin	Domain

• Sequence:

  MKFILLWALLNLTVALAFNPDYTVSSTPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLP
  KLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLA
  NLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLC
  VGIVPGRRQPCKEVSAAPAICNGMLQGILSFADGCVLRADVGIYAKIFYYIPWIENVIQN
  N

• Sequence length: 241

Related Genes

No strongly related genes found yet for PRSS58.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PRSS58.