PRRG3 (proline rich and Gla domain 3)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 79057
• Gene name: Proline rich and Gla domain 3
• Gene symbol: PRRG3
• Synonyms (NCBI Gene): PRGP3, TMG3
• Chromosome: X
• Chromosome location: Xq28
• Summary: This gene encodes a protein which contains a vitamin K-dependent carboxylation/gamma-carboxyglutamic domain. The encoded protein is a member of a family of vitamin K-dependent transmembrane proteins which contain a glutamate-rich extracellular domain. [pr

miRNA Show/Hide all (263)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028930	hsa-miR-26b-5p	Microarray	19088304
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23313552
MIRT610517	hsa-miR-8485	HITS-CLIP	23313552
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23313552
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT645874	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT645873	hsa-miR-6771-3p	HITS-CLIP	23824327
MIRT645872	hsa-miR-8070	HITS-CLIP	23824327
MIRT645871	hsa-miR-758-3p	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT635368	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT635367	hsa-miR-587	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23313552
MIRT610517	hsa-miR-8485	HITS-CLIP	23313552
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23313552
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT645874	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT645873	hsa-miR-6771-3p	HITS-CLIP	23824327
MIRT645872	hsa-miR-8070	HITS-CLIP	23824327
MIRT645871	hsa-miR-758-3p	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT635369	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT635368	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT635367	hsa-miR-587	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT619152	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619151	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT613984	hsa-miR-603	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT613983	hsa-miR-3941	HITS-CLIP	23824327
MIRT610517	hsa-miR-8485	HITS-CLIP	23824327
MIRT610516	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610515	hsa-miR-376c-3p	HITS-CLIP	23824327
MIRT1267920	hsa-miR-1178	CLIP-seq
MIRT1267921	hsa-miR-1910	CLIP-seq
MIRT1267922	hsa-miR-339-5p	CLIP-seq
MIRT1267923	hsa-miR-3909	CLIP-seq
MIRT1267924	hsa-miR-4264	CLIP-seq
MIRT1267925	hsa-miR-4436a	CLIP-seq
MIRT1267926	hsa-miR-455-3p	CLIP-seq
MIRT1267927	hsa-miR-4646-3p	CLIP-seq
MIRT1267928	hsa-miR-4691-5p	CLIP-seq
MIRT1267929	hsa-miR-548a-3p	CLIP-seq
MIRT1267930	hsa-miR-548e	CLIP-seq
MIRT1267931	hsa-miR-548f	CLIP-seq
MIRT1267932	hsa-miR-549	CLIP-seq
MIRT1267933	hsa-miR-583	CLIP-seq
MIRT1267934	hsa-miR-617	CLIP-seq
MIRT1267935	hsa-miR-665	CLIP-seq

Gene ontology (GO) Show/Hide all (8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004252	Function	Serine-type endopeptidase activity	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IBA
GO:0006508	Process	Proteolysis	IBA
GO:0007596	Process	Blood coagulation	IBA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	11171957

Other IDs

• MIM: 300685
• HGNC: 30798
• e!Ensembl: ENSG00000130032

Protein

• UniProt ID: Q9BZD7
• Protein name: Transmembrane gamma-carboxyglutamic acid protein 3 (Proline-rich gamma-carboxyglutamic acid protein 3) (Proline-rich Gla protein 3)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00594	Gla	24 → 64	Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in brain, lung, kidney and heart. {ECO:0000269|PubMed:11171957}.
• Sequence:

  MAVFLEAKDAHSVLKRFPRANEFLEELRQGTIERECMEEICSYEEVKEVFENKEKTMEFW
  KGYPNAVYSVRDPSQSSDAMYVVVPLLGVALLIVIALFIIWRCQLQKATRHHPSYAQNRY
  LASRAGHTLPRVMVYRGTVHSQGEPSGHREAANSPQVVLGPSRGGRTTVRLESTLYLPEL
  SLSRLSSTTPPPSYEEVTAPQESSSEEASVSYSDPPPKYEEIVAANPGADK

• Sequence length: 231

Related Genes

No strongly related genes found yet for PRRG3.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PRRG3.