Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs Other IDs Associated diseases
Entrez ID	5567
Gene name	Protein kinase cAMP-activated catalytic subunit beta
Gene symbol	PRKACB
Synonyms (NCBI Gene)	CAFD2PKA C-betaPKACB
Chromosome	1
Chromosome location	1p31.1
Summary	The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a n

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miRTarBase ID	miRNA	Experiments	Reference
MIRT006806	hsa-miR-23b-3p	Luciferase reporter assayqRT-PCR	22449550
MIRT027986	hsa-miR-93-5p	Sequencing	20371350
MIRT031110	hsa-miR-19b-3p	Sequencing	20371350
MIRT006806	hsa-miR-23b-3p	Luciferase reporter assayImmunocytochemistryWestern blot	24916040
MIRT080186	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT080199	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT080182	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT080183	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT080190	hsa-miR-520e	PAR-CLIP	21572407
MIRT080184	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT080197	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT080185	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT080206	hsa-miR-302e	PAR-CLIP	21572407
MIRT080196	hsa-miR-520b	PAR-CLIP	21572407
MIRT080193	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT080187	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT080198	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT080194	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT027986	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT080181	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT080178	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT080176	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT080188	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT080179	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT080177	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT031110	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT080210	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT080201	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT080207	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT555219	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT555218	hsa-miR-4724-5p	PAR-CLIP	21572407
MIRT080184	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT080191	hsa-miR-520f-3p	PAR-CLIP	21572407
MIRT080211	hsa-miR-3622a-3p	PAR-CLIP	21572407
MIRT080212	hsa-miR-3622b-3p	PAR-CLIP	21572407
MIRT555217	hsa-miR-4539	PAR-CLIP	21572407
MIRT080214	hsa-miR-3660	PAR-CLIP	21572407
MIRT080216	hsa-miR-4526	PAR-CLIP	21572407
MIRT555216	hsa-miR-2277-3p	PAR-CLIP	21572407
MIRT080215	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT080204	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT080205	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT080209	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT555215	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT080203	hsa-miR-636	PAR-CLIP	21572407
MIRT080180	hsa-miR-203a-3p	PAR-CLIP	21572407
MIRT555214	hsa-miR-7158-3p	PAR-CLIP	21572407
MIRT080217	hsa-miR-548aw	PAR-CLIP	21572407
MIRT080213	hsa-miR-1273e	PAR-CLIP	21572407
MIRT555213	hsa-miR-3692-3p	PAR-CLIP	21572407
MIRT080186	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT080199	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT080182	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT080183	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT080190	hsa-miR-520e	PAR-CLIP	21572407
MIRT080184	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT080197	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT080185	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT080206	hsa-miR-302e	PAR-CLIP	21572407
MIRT080196	hsa-miR-520b	PAR-CLIP	21572407
MIRT080193	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT080187	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT080198	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT080194	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT027986	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT080181	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT080178	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT080176	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT080188	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT080179	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT080177	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT031110	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT080210	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT080201	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT080207	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT555219	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT555218	hsa-miR-4724-5p	PAR-CLIP	21572407
MIRT080184	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT080191	hsa-miR-520f-3p	PAR-CLIP	21572407
MIRT080211	hsa-miR-3622a-3p	PAR-CLIP	21572407
MIRT080212	hsa-miR-3622b-3p	PAR-CLIP	21572407
MIRT555217	hsa-miR-4539	PAR-CLIP	21572407
MIRT080214	hsa-miR-3660	PAR-CLIP	21572407
MIRT080216	hsa-miR-4526	PAR-CLIP	21572407
MIRT555216	hsa-miR-2277-3p	PAR-CLIP	21572407
MIRT080215	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT080204	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT080205	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT080209	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT555215	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT080203	hsa-miR-636	PAR-CLIP	21572407
MIRT080180	hsa-miR-203a-3p	PAR-CLIP	21572407
MIRT555214	hsa-miR-7158-3p	PAR-CLIP	21572407
MIRT080217	hsa-miR-548aw	PAR-CLIP	21572407
MIRT080213	hsa-miR-1273e	PAR-CLIP	21572407
MIRT555213	hsa-miR-3692-3p	PAR-CLIP	21572407
MIRT737833	hsa-miR-1	CLIP-seq
MIRT1262336	hsa-miR-1245b-3p	CLIP-seq
MIRT737830	hsa-miR-1252	CLIP-seq
MIRT737836	hsa-miR-1306	CLIP-seq
MIRT1262337	hsa-miR-1324	CLIP-seq
MIRT737834	hsa-miR-206	CLIP-seq
MIRT1262338	hsa-miR-2110	CLIP-seq
MIRT1262339	hsa-miR-3074-5p	CLIP-seq
MIRT1262340	hsa-miR-3163	CLIP-seq
MIRT1262341	hsa-miR-3647-3p	CLIP-seq
MIRT737835	hsa-miR-3673	CLIP-seq
MIRT1262342	hsa-miR-370	CLIP-seq
MIRT737831	hsa-miR-4264	CLIP-seq
MIRT1262343	hsa-miR-4271	CLIP-seq
MIRT1262344	hsa-miR-4330	CLIP-seq
MIRT1262345	hsa-miR-4668-3p	CLIP-seq
MIRT1262346	hsa-miR-4668-5p	CLIP-seq
MIRT1262347	hsa-miR-4725-3p	CLIP-seq
MIRT1262348	hsa-miR-577	CLIP-seq
MIRT737832	hsa-miR-613	CLIP-seq
MIRT1262349	hsa-miR-548k	CLIP-seq
MIRT1262350	hsa-miR-548n	CLIP-seq
MIRT737833	hsa-miR-1	CLIP-seq
MIRT737830	hsa-miR-1252	CLIP-seq
MIRT737836	hsa-miR-1306	CLIP-seq
MIRT737834	hsa-miR-206	CLIP-seq
MIRT737835	hsa-miR-3673	CLIP-seq
MIRT737831	hsa-miR-4264	CLIP-seq
MIRT737832	hsa-miR-613	CLIP-seq
MIRT737833	hsa-miR-1	CLIP-seq
MIRT737830	hsa-miR-1252	CLIP-seq
MIRT737836	hsa-miR-1306	CLIP-seq
MIRT737834	hsa-miR-206	CLIP-seq
MIRT1262339	hsa-miR-3074-5p	CLIP-seq
MIRT737835	hsa-miR-3673	CLIP-seq
MIRT1262342	hsa-miR-370	CLIP-seq
MIRT737831	hsa-miR-4264	CLIP-seq
MIRT737832	hsa-miR-613	CLIP-seq
MIRT2303782	hsa-miR-101	CLIP-seq
MIRT2303783	hsa-miR-103a	CLIP-seq
MIRT2303784	hsa-miR-107	CLIP-seq
MIRT2303785	hsa-miR-1197	CLIP-seq
MIRT2303786	hsa-miR-1238	CLIP-seq
MIRT1262336	hsa-miR-1245b-3p	CLIP-seq
MIRT2303787	hsa-miR-1301	CLIP-seq
MIRT2303788	hsa-miR-130a	CLIP-seq
MIRT2303789	hsa-miR-130b	CLIP-seq
MIRT2303790	hsa-miR-139-5p	CLIP-seq
MIRT2303791	hsa-miR-141	CLIP-seq
MIRT2303792	hsa-miR-144	CLIP-seq
MIRT2303793	hsa-miR-154	CLIP-seq
MIRT2303794	hsa-miR-18a	CLIP-seq
MIRT2303795	hsa-miR-18b	CLIP-seq
MIRT2303796	hsa-miR-199a-3p	CLIP-seq
MIRT2303797	hsa-miR-199b-3p	CLIP-seq
MIRT2303798	hsa-miR-19a	CLIP-seq
MIRT2303799	hsa-miR-19b	CLIP-seq
MIRT2303800	hsa-miR-200a	CLIP-seq
MIRT2303801	hsa-miR-204	CLIP-seq
MIRT2303802	hsa-miR-211	CLIP-seq
MIRT2303803	hsa-miR-23a	CLIP-seq
MIRT2303804	hsa-miR-23b	CLIP-seq
MIRT2303805	hsa-miR-23c	CLIP-seq
MIRT2303806	hsa-miR-298	CLIP-seq
MIRT2303807	hsa-miR-301a	CLIP-seq
MIRT2303808	hsa-miR-301b	CLIP-seq
MIRT2303809	hsa-miR-3117-3p	CLIP-seq
MIRT2303810	hsa-miR-3124-3p	CLIP-seq
MIRT2303811	hsa-miR-3129-5p	CLIP-seq
MIRT2303812	hsa-miR-3145-3p	CLIP-seq
MIRT2303813	hsa-miR-3153	CLIP-seq
MIRT2303814	hsa-miR-3160-5p	CLIP-seq
MIRT2303815	hsa-miR-3162-3p	CLIP-seq
MIRT1262340	hsa-miR-3163	CLIP-seq
MIRT2303816	hsa-miR-3173-3p	CLIP-seq
MIRT2303817	hsa-miR-323-3p	CLIP-seq
MIRT2303818	hsa-miR-3617	CLIP-seq
MIRT2303819	hsa-miR-3659	CLIP-seq
MIRT2303820	hsa-miR-3666	CLIP-seq
MIRT2303821	hsa-miR-3671	CLIP-seq
MIRT2303822	hsa-miR-3675-3p	CLIP-seq
MIRT2303823	hsa-miR-3685	CLIP-seq
MIRT2303824	hsa-miR-371b-3p	CLIP-seq
MIRT2303825	hsa-miR-375	CLIP-seq
MIRT2303826	hsa-miR-384	CLIP-seq
MIRT2303827	hsa-miR-3942-5p	CLIP-seq
MIRT2303828	hsa-miR-421	CLIP-seq
MIRT2303829	hsa-miR-4272	CLIP-seq
MIRT2303830	hsa-miR-4282	CLIP-seq
MIRT2303831	hsa-miR-4291	CLIP-seq
MIRT2303832	hsa-miR-4295	CLIP-seq
MIRT2303833	hsa-miR-4310	CLIP-seq
MIRT1262344	hsa-miR-4330	CLIP-seq
MIRT2303834	hsa-miR-4471	CLIP-seq
MIRT2303835	hsa-miR-4519	CLIP-seq
MIRT2303836	hsa-miR-454	CLIP-seq
MIRT2303837	hsa-miR-4658	CLIP-seq
MIRT2303838	hsa-miR-4671-3p	CLIP-seq
MIRT2303839	hsa-miR-4703-5p	CLIP-seq
MIRT2303840	hsa-miR-4709-5p	CLIP-seq
MIRT2303841	hsa-miR-4735-3p	CLIP-seq
MIRT2303842	hsa-miR-4749-3p	CLIP-seq
MIRT2303843	hsa-miR-4755-5p	CLIP-seq
MIRT2303844	hsa-miR-4761-5p	CLIP-seq
MIRT2303845	hsa-miR-4779	CLIP-seq
MIRT2303846	hsa-miR-4797-5p	CLIP-seq
MIRT2303847	hsa-miR-5047	CLIP-seq
MIRT2303848	hsa-miR-509-3p	CLIP-seq
MIRT2303849	hsa-miR-548v	CLIP-seq
MIRT2303850	hsa-miR-574-5p	CLIP-seq
MIRT2303851	hsa-miR-582-5p	CLIP-seq
MIRT2303852	hsa-miR-600	CLIP-seq
MIRT2303853	hsa-miR-607	CLIP-seq
MIRT2303854	hsa-miR-623	CLIP-seq
MIRT2303855	hsa-miR-624	CLIP-seq
MIRT2303856	hsa-miR-641	CLIP-seq
MIRT2303857	hsa-miR-645	CLIP-seq
MIRT2303858	hsa-miR-654-3p	CLIP-seq
MIRT2303859	hsa-miR-660	CLIP-seq
MIRT2303860	hsa-miR-759	CLIP-seq
MIRT2303861	hsa-miR-889	CLIP-seq
MIRT2303803	hsa-miR-23a	CLIP-seq
MIRT2303804	hsa-miR-23b	CLIP-seq
MIRT2303805	hsa-miR-23c	CLIP-seq
MIRT2303814	hsa-miR-3160-5p	CLIP-seq
MIRT2303817	hsa-miR-323-3p	CLIP-seq
MIRT2432267	hsa-miR-579	CLIP-seq
MIRT2303791	hsa-miR-141	CLIP-seq
MIRT2303800	hsa-miR-200a	CLIP-seq
MIRT2600666	hsa-miR-200b	CLIP-seq
MIRT2600667	hsa-miR-200c	CLIP-seq
MIRT2600668	hsa-miR-429	CLIP-seq
MIRT2600669	hsa-miR-548t	CLIP-seq
MIRT737833	hsa-miR-1	CLIP-seq
MIRT2600670	hsa-miR-1178	CLIP-seq
MIRT2600671	hsa-miR-1185	CLIP-seq
MIRT2600672	hsa-miR-1207-3p	CLIP-seq
MIRT1262336	hsa-miR-1245b-3p	CLIP-seq
MIRT2600673	hsa-miR-1285	CLIP-seq
MIRT2600674	hsa-miR-129-3p	CLIP-seq
MIRT2600675	hsa-miR-1323	CLIP-seq
MIRT2303790	hsa-miR-139-5p	CLIP-seq
MIRT2303791	hsa-miR-141	CLIP-seq
MIRT2303793	hsa-miR-154	CLIP-seq
MIRT2600676	hsa-miR-182	CLIP-seq
MIRT2303800	hsa-miR-200a	CLIP-seq
MIRT2600666	hsa-miR-200b	CLIP-seq
MIRT2600667	hsa-miR-200c	CLIP-seq
MIRT2600677	hsa-miR-2053	CLIP-seq
MIRT737834	hsa-miR-206	CLIP-seq
MIRT1262338	hsa-miR-2110	CLIP-seq
MIRT2600678	hsa-miR-223	CLIP-seq
MIRT2600679	hsa-miR-224	CLIP-seq
MIRT2600680	hsa-miR-3121-3p	CLIP-seq
MIRT2303812	hsa-miR-3145-3p	CLIP-seq
MIRT2600681	hsa-miR-3148	CLIP-seq
MIRT2303813	hsa-miR-3153	CLIP-seq
MIRT2600682	hsa-miR-3157-3p	CLIP-seq
MIRT1262340	hsa-miR-3163	CLIP-seq
MIRT2303816	hsa-miR-3173-3p	CLIP-seq
MIRT2600683	hsa-miR-3182	CLIP-seq
MIRT2600684	hsa-miR-3187-5p	CLIP-seq
MIRT2600685	hsa-miR-330-3p	CLIP-seq
MIRT2600686	hsa-miR-338-5p	CLIP-seq
MIRT2600687	hsa-miR-3591-5p	CLIP-seq
MIRT2600688	hsa-miR-3613-3p	CLIP-seq
MIRT1262341	hsa-miR-3647-3p	CLIP-seq
MIRT2600689	hsa-miR-3651	CLIP-seq
MIRT2600690	hsa-miR-3653	CLIP-seq
MIRT2600691	hsa-miR-3658	CLIP-seq
MIRT2600692	hsa-miR-3662	CLIP-seq
MIRT2303821	hsa-miR-3671	CLIP-seq
MIRT2600693	hsa-miR-3672	CLIP-seq
MIRT737835	hsa-miR-3673	CLIP-seq
MIRT2600694	hsa-miR-3679-5p	CLIP-seq
MIRT2600695	hsa-miR-3682-5p	CLIP-seq
MIRT2600696	hsa-miR-371b-5p	CLIP-seq
MIRT2600697	hsa-miR-380	CLIP-seq
MIRT2600698	hsa-miR-3908	CLIP-seq
MIRT2600699	hsa-miR-3919	CLIP-seq
MIRT2600700	hsa-miR-3923	CLIP-seq
MIRT2600701	hsa-miR-3927	CLIP-seq
MIRT2600702	hsa-miR-3941	CLIP-seq
MIRT2303827	hsa-miR-3942-5p	CLIP-seq
MIRT2600703	hsa-miR-3976	CLIP-seq
MIRT2600704	hsa-miR-409-3p	CLIP-seq
MIRT1262343	hsa-miR-4271	CLIP-seq
MIRT2303829	hsa-miR-4272	CLIP-seq
MIRT2600705	hsa-miR-4280	CLIP-seq
MIRT2600706	hsa-miR-4287	CLIP-seq
MIRT2600668	hsa-miR-429	CLIP-seq
MIRT2600707	hsa-miR-4427	CLIP-seq
MIRT2600708	hsa-miR-4428	CLIP-seq
MIRT2600709	hsa-miR-4438	CLIP-seq
MIRT2600710	hsa-miR-4461	CLIP-seq
MIRT2600711	hsa-miR-4470	CLIP-seq
MIRT2600712	hsa-miR-4495	CLIP-seq
MIRT2600713	hsa-miR-4511	CLIP-seq
MIRT2600714	hsa-miR-4645-3p	CLIP-seq
MIRT2600715	hsa-miR-4646-5p	CLIP-seq
MIRT2600716	hsa-miR-4652-3p	CLIP-seq
MIRT2600717	hsa-miR-466	CLIP-seq
MIRT1262345	hsa-miR-4668-3p	CLIP-seq
MIRT1262346	hsa-miR-4668-5p	CLIP-seq
MIRT2600718	hsa-miR-4672	CLIP-seq
MIRT2600719	hsa-miR-4685-3p	CLIP-seq
MIRT2600720	hsa-miR-4687-5p	CLIP-seq
MIRT2600721	hsa-miR-4694-3p	CLIP-seq
MIRT2600722	hsa-miR-4698	CLIP-seq
MIRT2600723	hsa-miR-4699-3p	CLIP-seq
MIRT2303839	hsa-miR-4703-5p	CLIP-seq
MIRT2600724	hsa-miR-4715-5p	CLIP-seq
MIRT1262347	hsa-miR-4725-3p	CLIP-seq
MIRT2600725	hsa-miR-4731-3p	CLIP-seq
MIRT2600726	hsa-miR-4735-5p	CLIP-seq
MIRT2600727	hsa-miR-4738-3p	CLIP-seq
MIRT2600728	hsa-miR-4756-3p	CLIP-seq
MIRT2600729	hsa-miR-4775	CLIP-seq
MIRT2303845	hsa-miR-4779	CLIP-seq
MIRT2600730	hsa-miR-4780	CLIP-seq
MIRT2600731	hsa-miR-4801	CLIP-seq
MIRT2600732	hsa-miR-4803	CLIP-seq
MIRT2303848	hsa-miR-509-3p	CLIP-seq
MIRT2600733	hsa-miR-548aa	CLIP-seq
MIRT2600734	hsa-miR-548ag	CLIP-seq
MIRT2600735	hsa-miR-548ai	CLIP-seq
MIRT2600736	hsa-miR-548b-3p	CLIP-seq
MIRT2600737	hsa-miR-548c-3p	CLIP-seq
MIRT2600738	hsa-miR-548o	CLIP-seq
MIRT2600669	hsa-miR-548t	CLIP-seq
MIRT2600739	hsa-miR-563	CLIP-seq
MIRT2600740	hsa-miR-576-5p	CLIP-seq
MIRT1262348	hsa-miR-577	CLIP-seq
MIRT2600741	hsa-miR-590-3p	CLIP-seq
MIRT2303853	hsa-miR-607	CLIP-seq
MIRT2600742	hsa-miR-612	CLIP-seq
MIRT737832	hsa-miR-613	CLIP-seq
MIRT2303854	hsa-miR-623	CLIP-seq
MIRT2600743	hsa-miR-628-3p	CLIP-seq
MIRT2303858	hsa-miR-654-3p	CLIP-seq
MIRT2303859	hsa-miR-660	CLIP-seq
MIRT2600744	hsa-miR-888	CLIP-seq
MIRT2303861	hsa-miR-889	CLIP-seq
MIRT2600745	hsa-miR-944	CLIP-seq
MIRT737833	hsa-miR-1	CLIP-seq
MIRT2600670	hsa-miR-1178	CLIP-seq
MIRT2600671	hsa-miR-1185	CLIP-seq
MIRT2600672	hsa-miR-1207-3p	CLIP-seq
MIRT2688599	hsa-miR-1208	CLIP-seq
MIRT1262336	hsa-miR-1245b-3p	CLIP-seq
MIRT2688600	hsa-miR-1246	CLIP-seq
MIRT2600674	hsa-miR-129-3p	CLIP-seq
MIRT2688601	hsa-miR-1303	CLIP-seq
MIRT2600675	hsa-miR-1323	CLIP-seq
MIRT2303790	hsa-miR-139-5p	CLIP-seq
MIRT2303791	hsa-miR-141	CLIP-seq
MIRT2600676	hsa-miR-182	CLIP-seq
MIRT2303800	hsa-miR-200a	CLIP-seq
MIRT2600677	hsa-miR-2053	CLIP-seq
MIRT737834	hsa-miR-206	CLIP-seq
MIRT1262338	hsa-miR-2110	CLIP-seq
MIRT2600678	hsa-miR-223	CLIP-seq
MIRT2600679	hsa-miR-224	CLIP-seq
MIRT2688602	hsa-miR-3065-5p	CLIP-seq
MIRT2600680	hsa-miR-3121-3p	CLIP-seq
MIRT2688603	hsa-miR-3123	CLIP-seq
MIRT2303812	hsa-miR-3145-3p	CLIP-seq
MIRT2600681	hsa-miR-3148	CLIP-seq
MIRT2688604	hsa-miR-3150a-5p	CLIP-seq
MIRT2688605	hsa-miR-3150b-5p	CLIP-seq
MIRT2303813	hsa-miR-3153	CLIP-seq
MIRT2600682	hsa-miR-3157-3p	CLIP-seq
MIRT1262340	hsa-miR-3163	CLIP-seq
MIRT2303816	hsa-miR-3173-3p	CLIP-seq
MIRT2600683	hsa-miR-3182	CLIP-seq
MIRT2600686	hsa-miR-338-5p	CLIP-seq
MIRT2688606	hsa-miR-3591-3p	CLIP-seq
MIRT2600687	hsa-miR-3591-5p	CLIP-seq
MIRT2600688	hsa-miR-3613-3p	CLIP-seq
MIRT1262341	hsa-miR-3647-3p	CLIP-seq
MIRT2600689	hsa-miR-3651	CLIP-seq
MIRT2600690	hsa-miR-3653	CLIP-seq
MIRT2600691	hsa-miR-3658	CLIP-seq
MIRT2600692	hsa-miR-3662	CLIP-seq
MIRT2303821	hsa-miR-3671	CLIP-seq
MIRT2600693	hsa-miR-3672	CLIP-seq
MIRT737835	hsa-miR-3673	CLIP-seq
MIRT2600694	hsa-miR-3679-5p	CLIP-seq
MIRT2688607	hsa-miR-371-5p	CLIP-seq
MIRT2600696	hsa-miR-371b-5p	CLIP-seq
MIRT2600697	hsa-miR-380	CLIP-seq
MIRT2600698	hsa-miR-3908	CLIP-seq
MIRT2600699	hsa-miR-3919	CLIP-seq
MIRT2688608	hsa-miR-3925-5p	CLIP-seq
MIRT2600701	hsa-miR-3927	CLIP-seq
MIRT2600702	hsa-miR-3941	CLIP-seq
MIRT2303827	hsa-miR-3942-5p	CLIP-seq
MIRT2600703	hsa-miR-3976	CLIP-seq
MIRT2600704	hsa-miR-409-3p	CLIP-seq
MIRT1262343	hsa-miR-4271	CLIP-seq
MIRT2303829	hsa-miR-4272	CLIP-seq
MIRT2600705	hsa-miR-4280	CLIP-seq
MIRT2600706	hsa-miR-4287	CLIP-seq
MIRT2688609	hsa-miR-4320	CLIP-seq
MIRT2600707	hsa-miR-4427	CLIP-seq
MIRT2600708	hsa-miR-4428	CLIP-seq
MIRT2600709	hsa-miR-4438	CLIP-seq
MIRT2600711	hsa-miR-4470	CLIP-seq
MIRT2303834	hsa-miR-4471	CLIP-seq
MIRT2600712	hsa-miR-4495	CLIP-seq
MIRT2688610	hsa-miR-4496	CLIP-seq
MIRT2600713	hsa-miR-4511	CLIP-seq
MIRT2688611	hsa-miR-452	CLIP-seq
MIRT2600714	hsa-miR-4645-3p	CLIP-seq
MIRT2600715	hsa-miR-4646-5p	CLIP-seq
MIRT2600716	hsa-miR-4652-3p	CLIP-seq
MIRT2600717	hsa-miR-466	CLIP-seq
MIRT1262345	hsa-miR-4668-3p	CLIP-seq
MIRT1262346	hsa-miR-4668-5p	CLIP-seq
MIRT2600718	hsa-miR-4672	CLIP-seq
MIRT2688612	hsa-miR-4676-3p	CLIP-seq
MIRT2600719	hsa-miR-4685-3p	CLIP-seq
MIRT2600720	hsa-miR-4687-5p	CLIP-seq
MIRT2600721	hsa-miR-4694-3p	CLIP-seq
MIRT2600723	hsa-miR-4699-3p	CLIP-seq
MIRT2303839	hsa-miR-4703-5p	CLIP-seq
MIRT2600724	hsa-miR-4715-5p	CLIP-seq
MIRT1262347	hsa-miR-4725-3p	CLIP-seq
MIRT2600725	hsa-miR-4731-3p	CLIP-seq
MIRT2600726	hsa-miR-4735-5p	CLIP-seq
MIRT2600727	hsa-miR-4738-3p	CLIP-seq
MIRT2600728	hsa-miR-4756-3p	CLIP-seq
MIRT2600729	hsa-miR-4775	CLIP-seq
MIRT2303845	hsa-miR-4779	CLIP-seq
MIRT2600730	hsa-miR-4780	CLIP-seq
MIRT2600731	hsa-miR-4801	CLIP-seq
MIRT2600732	hsa-miR-4803	CLIP-seq
MIRT2688613	hsa-miR-489	CLIP-seq
MIRT2688614	hsa-miR-490-5p	CLIP-seq
MIRT2688615	hsa-miR-494	CLIP-seq
MIRT2303848	hsa-miR-509-3p	CLIP-seq
MIRT2600733	hsa-miR-548aa	CLIP-seq
MIRT2688616	hsa-miR-548ae	CLIP-seq
MIRT2600734	hsa-miR-548ag	CLIP-seq
MIRT2600735	hsa-miR-548ai	CLIP-seq
MIRT2688617	hsa-miR-548aj	CLIP-seq
MIRT2688618	hsa-miR-548am	CLIP-seq
MIRT2600736	hsa-miR-548b-3p	CLIP-seq
MIRT2600737	hsa-miR-548c-3p	CLIP-seq
MIRT2600738	hsa-miR-548o	CLIP-seq
MIRT2688619	hsa-miR-548p	CLIP-seq
MIRT2600669	hsa-miR-548t	CLIP-seq
MIRT2688620	hsa-miR-548x	CLIP-seq
MIRT2600739	hsa-miR-563	CLIP-seq
MIRT2600740	hsa-miR-576-5p	CLIP-seq
MIRT1262348	hsa-miR-577	CLIP-seq
MIRT2600741	hsa-miR-590-3p	CLIP-seq
MIRT2303853	hsa-miR-607	CLIP-seq
MIRT737832	hsa-miR-613	CLIP-seq
MIRT2303854	hsa-miR-623	CLIP-seq
MIRT2303858	hsa-miR-654-3p	CLIP-seq
MIRT2303859	hsa-miR-660	CLIP-seq
MIRT2600744	hsa-miR-888	CLIP-seq
MIRT2303861	hsa-miR-889	CLIP-seq
MIRT2600745	hsa-miR-944	CLIP-seq

Show/Hide all (44)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000287	Function	Magnesium ion binding	IDA	12420224
GO:0000287	Function	Magnesium ion binding	IEA
GO:0001843	Process	Neural tube closure	IEA
GO:0003091	Process	Renal water homeostasis	TAS
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	TAS
GO:0004691	Function	CAMP-dependent protein kinase activity	IBA
GO:0004691	Function	CAMP-dependent protein kinase activity	IDA	12420224, 31112131
GO:0004691	Function	CAMP-dependent protein kinase activity	IEA
GO:0004691	Function	CAMP-dependent protein kinase activity	TAS	2342480
GO:0005515	Function	Protein binding	IPI	21880142, 22939624, 23455922, 25416956, 32296183, 32814053
GO:0005524	Function	ATP binding	IDA	12420224
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	21399614
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IEA
GO:0005952	Component	CAMP-dependent protein kinase complex	IBA
GO:0005952	Component	CAMP-dependent protein kinase complex	TAS	12420224
GO:0006468	Process	Protein phosphorylation	IDA	12420224, 21880142
GO:0007165	Process	Signal transduction	TAS	2342480
GO:0007188	Process	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway	TAS	12420224
GO:0007189	Process	Adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IDA	21423175
GO:0031669	Process	Cellular response to nutrient levels	IDA	12747827, 29750193
GO:0034380	Process	High-density lipoprotein particle assembly	TAS
GO:0038202	Process	TORC1 signaling	IDA	12747827, 29750193
GO:0045879	Process	Negative regulation of smoothened signaling pathway	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0070613	Process	Regulation of protein processing	IEA
GO:0097546	Component	Ciliary base	IEA
GO:0097546	Component	Ciliary base	TAS
GO:0097700	Process	Vascular endothelial cell response to laminar fluid shear stress	TAS
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1904262	Process	Negative regulation of TORC1 signaling	IDA	31112131

MIM	HGNC	e!Ensembl
176892	9381	ENSG00000142875

P22694

Protein name

cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)

Protein function

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs (PubMed:12420224, PubMed:21423175, PubMed:31112131). PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and reg

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	44 → 298	Protein kinase domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Isoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain. {ECO:0000269|PubMed:11589697}.

Sequence

MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML
VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT
TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF

Sequence length

351

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Cardioacrofacial dysplasia 2	Pathogenic	rs768056300, rs1670492319, rs1663748771, rs748898273	RCV002471543 RCV001271115 RCV001271116 RCV001271117 RCV001271118	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (10)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BILIARY TRACT NEOPLASMS	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHOLANGIOCARCINOMA	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CUSHING SYNDROME	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DESBUQUOIS SYNDROME	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DRY EYE SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ELLIS VAN CREVELD SYNDROME	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ELLIS-VAN CREVELD SYNDROME	—	Disgenet, GWAS catalog Disgenet, GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MALE BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PRKACB-related disorder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATIC NEOPLASMS	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (56)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acromegaly	Acromegaly	BEFREE	25225481		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenoma	Adenoma	BEFREE	29669941		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adrenal Cortical Adenoma	Adrenocortical adenoma	BEFREE	25225481		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adrenal Cortical Adenoma	Adrenocortical adenoma	CTD_human_DG	29669941		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adrenal Gland Neoplasms	Adrenal neoplasia	BEFREE	29669941		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adrenal hyperplasia	Adrenal hyperplasia	BEFREE	26130139		★★★★★ ★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	29851783	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Anencephaly	Anencephaly	BEFREE	24294386		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anencephaly	Anencephaly	Pubtator	24294386	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	31678302		★★★★★ ★☆☆☆☆ Found in Text Mining only
Aphakia congenital primary	Congenital primary aphakia	Pubtator	29669941	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bile Duct Diseases	Bile duct disease	Pubtator	31678302	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Biliary Tract Cancer	Biliary Tract Cancer	CTD_human_DG	26258846		★★★★★ ★☆☆☆☆ Found in Text Mining only
Biliary Tract Neoplasm	Biliary Tract Neoplasm	CTD_human_DG	26258846		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	GWASDB_DG	23001122		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	GWASCAT_DG	23001122		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	25963740	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	26203557, 33201835	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	29669941	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carney Complex	Carney Complex	BEFREE	25225481		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	CTD_human_DG	26258846		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Cholangiocarcinoma	BEFREE	28389139, 28844952		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal Carcinoma	Colorectal Cancer	BEFREE	30951563		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	22034905, 28749961, 28902367, 36303457, 36793496	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital adrenal hyperplasia	Congenital adrenal hyperplasia	BEFREE	26130139		★★★★★ ★☆☆☆☆ Found in Text Mining only
Conn Adenoma	Conn Adenoma	CTD_human_DG	29669941		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cushing Syndrome	Cushing`s Syndrome	BEFREE	26130139		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cushing Syndrome	Cushing`s Syndrome	CTD_human_DG	29669941		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cushing Syndrome	Cushing syndrome	Pubtator	29669941	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Degenerative polyarthritis	Arthritis	BEFREE	24916040		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 1	Diabetes mellitus, type 1	Pubtator	36303457	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	32993798	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	22706224	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Extrahepatic Cholangiocarcinoma	Cholangiocarcinoma	CTD_human_DG	26258846		★★★★★ ★☆☆☆☆ Found in Text Mining only
Growth Hormone-Secreting Pituitary Adenoma	Somatotroph Adenoma	BEFREE	25225481		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	30347596	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	30867055	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Infertility	Infertility	Pubtator	36303457	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Intrahepatic Cholangiocarcinoma	Intrahepatic Cholangiocarcinoma	CTD_human_DG	26258846		★★★★★ ★☆☆☆☆ Found in Text Mining only
Intrahepatic Cholangiocarcinoma	Intrahepatic Cholangiocarcinoma	BEFREE	31255945		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	30037980		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	CTD_human_DG	16949795		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	22034905		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	36303457	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial infarction	Pubtator	35432334	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	25963740, 28749961		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neural Tube Defects	Neural Tube Defect	BEFREE	16080189, 24294386		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neural Tube Defects	Neural tube defect	Pubtator	16080189, 24294386	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	24916040	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Cyst	Pancreatic cyst	Pubtator	31678302	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	31678302	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	28765971		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	28765971	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	LHGDN	16949795		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic Neoplasms	CTD_human_DG	16949795		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Stomach Neoplasms	Stomach neoplasms	Pubtator	22034905	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

PRKACB (protein kinase cAMP-activated catalytic subunit beta)