PRAMEF1 (PRAME family member 1) | GeDiPNet

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Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	65121
Gene name	PRAME family member 1
Gene symbol	PRAMEF1
Synonyms (NCBI Gene)	-
Chromosome	1
Chromosome location	1p36.21
Summary	This gene is a member of the PRAME (preferentially expressed antigen of melanoma) gene family which is expressed in many cancers but may function in reproductive tissues during development. Alternative promoter usage generates two transcript variants, whi

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019126	hsa-miR-335-5p	Microarray	18185580
MIRT572928	hsa-miR-132-3p	PAR-CLIP	20371350
MIRT572927	hsa-miR-212-3p	PAR-CLIP	20371350
MIRT572926	hsa-miR-1183	PAR-CLIP	20371350
MIRT572925	hsa-miR-6760-3p	PAR-CLIP	20371350
MIRT572924	hsa-miR-1208	PAR-CLIP	20371350
MIRT572923	hsa-miR-6870-3p	PAR-CLIP	20371350
MIRT572922	hsa-miR-5579-3p	PAR-CLIP	20371350
MIRT572928	hsa-miR-132-3p	PAR-CLIP	20371350
MIRT572927	hsa-miR-212-3p	PAR-CLIP	20371350
MIRT572926	hsa-miR-1183	PAR-CLIP	20371350
MIRT572925	hsa-miR-6760-3p	PAR-CLIP	20371350
MIRT572924	hsa-miR-1208	PAR-CLIP	20371350
MIRT572923	hsa-miR-6870-3p	PAR-CLIP	20371350
MIRT572922	hsa-miR-5579-3p	PAR-CLIP	20371350
MIRT1259565	hsa-miR-3673	CLIP-seq
MIRT1259566	hsa-miR-4282	CLIP-seq
MIRT1259567	hsa-miR-4476	CLIP-seq
MIRT1259568	hsa-miR-4477a	CLIP-seq
MIRT1259569	hsa-miR-4649-3p	CLIP-seq
MIRT1259570	hsa-miR-548c-3p	CLIP-seq
MIRT1259571	hsa-miR-651	CLIP-seq
MIRT1259572	hsa-miR-944	CLIP-seq
MIRT2303132	hsa-miR-1827	CLIP-seq
MIRT1259567	hsa-miR-4476	CLIP-seq
MIRT1259569	hsa-miR-4649-3p	CLIP-seq
MIRT2303133	hsa-miR-4722-5p	CLIP-seq
MIRT1259571	hsa-miR-651	CLIP-seq
MIRT2303134	hsa-miR-940	CLIP-seq
MIRT1259565	hsa-miR-3673	CLIP-seq
MIRT1259566	hsa-miR-4282	CLIP-seq
MIRT1259568	hsa-miR-4477a	CLIP-seq
MIRT1259570	hsa-miR-548c-3p	CLIP-seq
MIRT1259572	hsa-miR-944	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IBA
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0031462	Component	Cul2-RING ubiquitin ligase complex	IBA
GO:0031462	Component	Cul2-RING ubiquitin ligase complex	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0045596	Process	Negative regulation of cell differentiation	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IBA
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein Protein information from UniProt database. Download as csv Download as pdf
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.	O95521
Protein name	PRAME family member 1
Family and domains
Sequence	MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS RCHHYTSDNELEGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ IHYSQLSAILPGLSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sequence length	474
Interactions	View interactions