PPP2R5E (protein phosphatase 2 regulatory subunit B'epsilon)

Gene

• Entrez ID: 5529
• Gene name: Protein phosphatase 2 regulatory subunit B'epsilon
• Gene symbol: PPP2R5E
• Synonyms (NCBI Gene): B56E, B56epsilon
• Chromosome: 14
• Chromosome location: 14q23.2
• Summary: The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a co

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT006743	hsa-miR-19b-3p	Luciferase reporter assay	20190740
MIRT006743	hsa-miR-19b-3p	Luciferase reporter assay	20190740
MIRT051983	hsa-let-7b-5p	CLASH	23622248
MIRT051753	hsa-let-7c-5p	CLASH	23622248
MIRT045699	hsa-miR-125a-5p	CLASH	23622248
MIRT044037	hsa-miR-365a-3p	CLASH	23622248
MIRT054034	hsa-miR-23a-3p	GFP reporter assay, qRT-PCR, Western blot	24997345
MIRT054034	hsa-miR-23a-3p	GFP reporter assay, qRT-PCR, Western blot	24997345
MIRT710559	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT710558	hsa-miR-510-3p	HITS-CLIP	19536157
MIRT542106	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT542104	hsa-miR-3163	HITS-CLIP	21572407
MIRT542105	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT542106	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT542104	hsa-miR-3163	HITS-CLIP	21572407
MIRT542105	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT622614	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT622613	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT622612	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT622611	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT622610	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT622609	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT622608	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT622614	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT622613	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT622612	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT622611	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT622610	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT622609	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT622608	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT542106	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT542104	hsa-miR-3163	PAR-CLIP	21572407
MIRT542105	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT470388	hsa-miR-19a-3p	PAR-CLIP	23592263
MIRT006743	hsa-miR-19b-3p	PAR-CLIP	23592263
MIRT470387	hsa-miR-181b-5p	PAR-CLIP	23592263
MIRT470386	hsa-miR-4262	PAR-CLIP	23592263
MIRT470385	hsa-miR-181d-5p	PAR-CLIP	23592263
MIRT470384	hsa-miR-181c-5p	PAR-CLIP	23592263
MIRT470383	hsa-miR-181a-5p	PAR-CLIP	23592263
MIRT470382	hsa-miR-4731-3p	PAR-CLIP	23592263
MIRT470381	hsa-miR-4801	PAR-CLIP	23592263
MIRT470380	hsa-miR-510-5p	PAR-CLIP	23592263
MIRT470379	hsa-miR-576-3p	PAR-CLIP	23592263
MIRT470378	hsa-miR-1265	PAR-CLIP	23592263
MIRT470377	hsa-miR-101-5p	PAR-CLIP	23592263
MIRT470376	hsa-miR-5586-5p	PAR-CLIP	23592263
MIRT470375	hsa-miR-6504-3p	PAR-CLIP	23592263
MIRT470374	hsa-miR-4272	PAR-CLIP	23592263
MIRT470373	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT470372	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT470371	hsa-miR-3664-3p	PAR-CLIP	23592263
MIRT470370	hsa-miR-3605-5p	PAR-CLIP	23592263
MIRT470369	hsa-miR-548aj-5p	PAR-CLIP	23592263
MIRT470368	hsa-miR-548f-5p	PAR-CLIP	23592263
MIRT470367	hsa-miR-548g-5p	PAR-CLIP	23592263
MIRT470366	hsa-miR-548x-5p	PAR-CLIP	23592263
MIRT470365	hsa-miR-1468-3p	PAR-CLIP	23592263
MIRT470364	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT470363	hsa-miR-3138	PAR-CLIP	23592263
MIRT470362	hsa-miR-3941	PAR-CLIP	23592263
MIRT470361	hsa-miR-4672	PAR-CLIP	23592263
MIRT470360	hsa-miR-466	PAR-CLIP	23592263
MIRT470359	hsa-miR-101-3p	PAR-CLIP	23592263
MIRT470358	hsa-miR-582-5p	PAR-CLIP	23592263
MIRT470357	hsa-miR-520a-5p	PAR-CLIP	23592263
MIRT470356	hsa-miR-525-5p	PAR-CLIP	23592263
MIRT470355	hsa-miR-548aw	PAR-CLIP	23592263
MIRT470354	hsa-miR-548l	PAR-CLIP	23592263
MIRT470353	hsa-miR-4712-3p	PAR-CLIP	23592263
MIRT470352	hsa-miR-3973	PAR-CLIP	23592263
MIRT470351	hsa-miR-520g-3p	PAR-CLIP	23592263
MIRT470350	hsa-miR-520h	PAR-CLIP	23592263
MIRT470349	hsa-miR-143-3p	PAR-CLIP	23592263
MIRT470348	hsa-miR-4770	PAR-CLIP	23592263
MIRT470347	hsa-miR-6088	PAR-CLIP	23592263
MIRT470346	hsa-miR-4708-5p	PAR-CLIP	23592263
MIRT470345	hsa-miR-1273f	PAR-CLIP	23592263
MIRT470344	hsa-miR-6794-3p	PAR-CLIP	23592263
MIRT470342	hsa-miR-4452	PAR-CLIP	23592263
MIRT470343	hsa-miR-1273e	PAR-CLIP	23592263
MIRT470341	hsa-miR-1262	PAR-CLIP	23592263
MIRT470339	hsa-miR-4701-3p	PAR-CLIP	23592263
MIRT470340	hsa-miR-6736-5p	PAR-CLIP	23592263
MIRT439912	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439912	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT006743	hsa-miR-19b-3p	Luciferase reporter assay	27720936
MIRT710559	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT710558	hsa-miR-510-3p	HITS-CLIP	19536157
MIRT542106	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT542104	hsa-miR-3163	HITS-CLIP	21572407
MIRT542105	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT542106	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT542104	hsa-miR-3163	HITS-CLIP	21572407
MIRT542105	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT622614	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT622613	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT622612	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT622611	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT622610	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT622609	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT622608	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT622614	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT622613	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT622612	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT622611	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT622610	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT622609	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT622608	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT542106	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT542104	hsa-miR-3163	PAR-CLIP	21572407
MIRT542105	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT542102	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT542103	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT542101	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT470388	hsa-miR-19a-3p	PAR-CLIP	23592263
MIRT006743	hsa-miR-19b-3p	PAR-CLIP	23592263
MIRT470387	hsa-miR-181b-5p	PAR-CLIP	23592263
MIRT470386	hsa-miR-4262	PAR-CLIP	23592263
MIRT470385	hsa-miR-181d-5p	PAR-CLIP	23592263
MIRT470384	hsa-miR-181c-5p	PAR-CLIP	23592263
MIRT470383	hsa-miR-181a-5p	PAR-CLIP	23592263
MIRT470382	hsa-miR-4731-3p	PAR-CLIP	23592263
MIRT470381	hsa-miR-4801	PAR-CLIP	23592263
MIRT470380	hsa-miR-510-5p	PAR-CLIP	23592263
MIRT470379	hsa-miR-576-3p	PAR-CLIP	23592263
MIRT470378	hsa-miR-1265	PAR-CLIP	23592263
MIRT470377	hsa-miR-101-5p	PAR-CLIP	23592263
MIRT470376	hsa-miR-5586-5p	PAR-CLIP	23592263
MIRT470375	hsa-miR-6504-3p	PAR-CLIP	23592263
MIRT470374	hsa-miR-4272	PAR-CLIP	23592263
MIRT470373	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT470372	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT470371	hsa-miR-3664-3p	PAR-CLIP	23592263
MIRT470370	hsa-miR-3605-5p	PAR-CLIP	23592263
MIRT470369	hsa-miR-548aj-5p	PAR-CLIP	23592263
MIRT470368	hsa-miR-548f-5p	PAR-CLIP	23592263
MIRT470367	hsa-miR-548g-5p	PAR-CLIP	23592263
MIRT470366	hsa-miR-548x-5p	PAR-CLIP	23592263
MIRT470365	hsa-miR-1468-3p	PAR-CLIP	23592263
MIRT470364	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT470363	hsa-miR-3138	PAR-CLIP	23592263
MIRT470362	hsa-miR-3941	PAR-CLIP	23592263
MIRT470361	hsa-miR-4672	PAR-CLIP	23592263
MIRT470360	hsa-miR-466	PAR-CLIP	23592263
MIRT470359	hsa-miR-101-3p	PAR-CLIP	23592263
MIRT470358	hsa-miR-582-5p	PAR-CLIP	23592263
MIRT470357	hsa-miR-520a-5p	PAR-CLIP	23592263
MIRT470356	hsa-miR-525-5p	PAR-CLIP	23592263
MIRT470355	hsa-miR-548aw	PAR-CLIP	23592263
MIRT470354	hsa-miR-548l	PAR-CLIP	23592263
MIRT470353	hsa-miR-4712-3p	PAR-CLIP	23592263
MIRT470352	hsa-miR-3973	PAR-CLIP	23592263
MIRT470351	hsa-miR-520g-3p	PAR-CLIP	23592263
MIRT470350	hsa-miR-520h	PAR-CLIP	23592263
MIRT470349	hsa-miR-143-3p	PAR-CLIP	23592263
MIRT470348	hsa-miR-4770	PAR-CLIP	23592263
MIRT470347	hsa-miR-6088	PAR-CLIP	23592263
MIRT470346	hsa-miR-4708-5p	PAR-CLIP	23592263
MIRT470345	hsa-miR-1273f	PAR-CLIP	23592263
MIRT470344	hsa-miR-6794-3p	PAR-CLIP	23592263
MIRT470342	hsa-miR-4452	PAR-CLIP	23592263
MIRT470343	hsa-miR-1273e	PAR-CLIP	23592263
MIRT470341	hsa-miR-1262	PAR-CLIP	23592263
MIRT470339	hsa-miR-4701-3p	PAR-CLIP	23592263
MIRT470340	hsa-miR-6736-5p	PAR-CLIP	23592263
MIRT1258104	hsa-miR-1303	CLIP-seq
MIRT1258105	hsa-miR-134	CLIP-seq
MIRT1258106	hsa-miR-3118	CLIP-seq
MIRT1258107	hsa-miR-3143	CLIP-seq
MIRT1258108	hsa-miR-3164	CLIP-seq
MIRT1258109	hsa-miR-326	CLIP-seq
MIRT1258110	hsa-miR-330-5p	CLIP-seq
MIRT1258111	hsa-miR-3616-5p	CLIP-seq
MIRT1258112	hsa-miR-3647-5p	CLIP-seq
MIRT1258113	hsa-miR-3658	CLIP-seq
MIRT1258114	hsa-miR-3674	CLIP-seq
MIRT1258115	hsa-miR-3908	CLIP-seq
MIRT1258116	hsa-miR-3942-5p	CLIP-seq
MIRT1258117	hsa-miR-409-3p	CLIP-seq
MIRT1258118	hsa-miR-421	CLIP-seq
MIRT1258119	hsa-miR-4263	CLIP-seq
MIRT1258120	hsa-miR-4445	CLIP-seq
MIRT1258121	hsa-miR-4490	CLIP-seq
MIRT1258122	hsa-miR-4524	CLIP-seq
MIRT1258123	hsa-miR-4645-3p	CLIP-seq
MIRT1258124	hsa-miR-4659a-3p	CLIP-seq
MIRT1258125	hsa-miR-4659b-3p	CLIP-seq
MIRT1258126	hsa-miR-4703-5p	CLIP-seq
MIRT1258127	hsa-miR-4709-5p	CLIP-seq
MIRT1258128	hsa-miR-4766-3p	CLIP-seq
MIRT1258129	hsa-miR-4774-5p	CLIP-seq
MIRT1258130	hsa-miR-4799-5p	CLIP-seq
MIRT1258131	hsa-miR-4803	CLIP-seq
MIRT1258132	hsa-miR-495	CLIP-seq
MIRT1258133	hsa-miR-512-3p	CLIP-seq
MIRT1258134	hsa-miR-513a-3p	CLIP-seq
MIRT1258135	hsa-miR-573	CLIP-seq
MIRT1258136	hsa-miR-576-5p	CLIP-seq
MIRT1258137	hsa-miR-590-3p	CLIP-seq
MIRT1258138	hsa-miR-616	CLIP-seq
MIRT2076042	hsa-miR-1179	CLIP-seq
MIRT2076043	hsa-miR-132	CLIP-seq
MIRT1258105	hsa-miR-134	CLIP-seq
MIRT2076044	hsa-miR-146a	CLIP-seq
MIRT2076045	hsa-miR-146b-5p	CLIP-seq
MIRT2076046	hsa-miR-199a-3p	CLIP-seq
MIRT2076047	hsa-miR-199b-3p	CLIP-seq
MIRT2076048	hsa-miR-200b	CLIP-seq
MIRT2076049	hsa-miR-200c	CLIP-seq
MIRT2076050	hsa-miR-212	CLIP-seq
MIRT1258106	hsa-miR-3118	CLIP-seq
MIRT2076051	hsa-miR-3129-5p	CLIP-seq
MIRT2076052	hsa-miR-3162-3p	CLIP-seq
MIRT1258108	hsa-miR-3164	CLIP-seq
MIRT2076053	hsa-miR-3180-5p	CLIP-seq
MIRT2076054	hsa-miR-374c	CLIP-seq
MIRT1258117	hsa-miR-409-3p	CLIP-seq
MIRT2076055	hsa-miR-4289	CLIP-seq
MIRT2076056	hsa-miR-429	CLIP-seq
MIRT2076057	hsa-miR-4307	CLIP-seq
MIRT2076058	hsa-miR-4436a	CLIP-seq
MIRT2076059	hsa-miR-4477a	CLIP-seq
MIRT2076060	hsa-miR-4509	CLIP-seq
MIRT2076061	hsa-miR-455-3p	CLIP-seq
MIRT2076062	hsa-miR-4679	CLIP-seq
MIRT2076063	hsa-miR-4735-5p	CLIP-seq
MIRT2076064	hsa-miR-4764-3p	CLIP-seq
MIRT2076065	hsa-miR-4768-5p	CLIP-seq
MIRT2076066	hsa-miR-4775	CLIP-seq
MIRT2076067	hsa-miR-4795-3p	CLIP-seq
MIRT2076068	hsa-miR-510	CLIP-seq
MIRT2076069	hsa-miR-512-5p	CLIP-seq
MIRT2076070	hsa-miR-548a-3p	CLIP-seq
MIRT2076071	hsa-miR-548e	CLIP-seq
MIRT2076072	hsa-miR-548f	CLIP-seq
MIRT2076073	hsa-miR-548g	CLIP-seq
MIRT2076074	hsa-miR-583	CLIP-seq
MIRT2076075	hsa-miR-589	CLIP-seq
MIRT1258137	hsa-miR-590-3p	CLIP-seq
MIRT1258138	hsa-miR-616	CLIP-seq
MIRT2076076	hsa-miR-655	CLIP-seq
MIRT2076077	hsa-miR-936	CLIP-seq
MIRT2076078	hsa-miR-942	CLIP-seq
MIRT2302639	hsa-miR-1178	CLIP-seq
MIRT2076042	hsa-miR-1179	CLIP-seq
MIRT2076046	hsa-miR-199a-3p	CLIP-seq
MIRT2076047	hsa-miR-199b-3p	CLIP-seq
MIRT2302640	hsa-miR-2964a-5p	CLIP-seq
MIRT2076051	hsa-miR-3129-5p	CLIP-seq
MIRT1258114	hsa-miR-3674	CLIP-seq
MIRT2302641	hsa-miR-4446-5p	CLIP-seq
MIRT2076061	hsa-miR-455-3p	CLIP-seq
MIRT2076062	hsa-miR-4679	CLIP-seq
MIRT2302642	hsa-miR-4724-5p	CLIP-seq
MIRT2302643	hsa-miR-4760-3p	CLIP-seq
MIRT2302644	hsa-miR-4786-3p	CLIP-seq
MIRT2076077	hsa-miR-936	CLIP-seq
MIRT2392924	hsa-miR-494	CLIP-seq
MIRT2599306	hsa-miR-1183	CLIP-seq
MIRT2599307	hsa-miR-1287	CLIP-seq
MIRT2599308	hsa-miR-194	CLIP-seq
MIRT2599309	hsa-miR-204	CLIP-seq
MIRT2599310	hsa-miR-211	CLIP-seq
MIRT2599311	hsa-miR-221	CLIP-seq
MIRT2599312	hsa-miR-222	CLIP-seq
MIRT2599313	hsa-miR-3135b	CLIP-seq
MIRT2076052	hsa-miR-3162-3p	CLIP-seq
MIRT2599314	hsa-miR-3607-3p	CLIP-seq
MIRT2599315	hsa-miR-3938	CLIP-seq
MIRT2599316	hsa-miR-3975	CLIP-seq
MIRT2076057	hsa-miR-4307	CLIP-seq
MIRT2302641	hsa-miR-4446-5p	CLIP-seq
MIRT2076060	hsa-miR-4509	CLIP-seq
MIRT2076063	hsa-miR-4735-5p	CLIP-seq
MIRT2599317	hsa-miR-4755-5p	CLIP-seq
MIRT2076064	hsa-miR-4764-3p	CLIP-seq
MIRT2076065	hsa-miR-4768-5p	CLIP-seq
MIRT2076066	hsa-miR-4775	CLIP-seq
MIRT2076070	hsa-miR-548a-3p	CLIP-seq
MIRT2076071	hsa-miR-548e	CLIP-seq
MIRT2076072	hsa-miR-548f	CLIP-seq
MIRT2599318	hsa-miR-561	CLIP-seq
MIRT1258137	hsa-miR-590-3p	CLIP-seq
MIRT2599319	hsa-miR-623	CLIP-seq
MIRT2076078	hsa-miR-942	CLIP-seq
MIRT2599308	hsa-miR-194	CLIP-seq
MIRT2599309	hsa-miR-204	CLIP-seq
MIRT2599310	hsa-miR-211	CLIP-seq
MIRT2599311	hsa-miR-221	CLIP-seq
MIRT2599312	hsa-miR-222	CLIP-seq
MIRT2076052	hsa-miR-3162-3p	CLIP-seq
MIRT2599315	hsa-miR-3938	CLIP-seq
MIRT2599316	hsa-miR-3975	CLIP-seq
MIRT2076057	hsa-miR-4307	CLIP-seq
MIRT2302641	hsa-miR-4446-5p	CLIP-seq
MIRT2599317	hsa-miR-4755-5p	CLIP-seq
MIRT2599319	hsa-miR-623	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000159	Component	Protein phosphatase type 2A complex	IBA
GO:0000159	Component	Protein phosphatase type 2A complex	IEA
GO:0005515	Function	Protein binding	IPI	15380617, 17540176, 18201571, 18782753, 19156129, 21699783, 21878643, 23555304, 24705354, 26496610, 27173435, 28330616, 30595372, 32814053, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	8703017
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0007165	Process	Signal transduction	IEA
GO:0019888	Function	Protein phosphatase regulator activity	IEA
GO:0019888	Function	Protein phosphatase regulator activity	TAS	8703017
GO:0072542	Function	Protein phosphatase activator activity	IBA

Other IDs

• MIM: 601647
• HGNC: 9313
• e!Ensembl: ENSG00000154001

Protein

• UniProt ID: Q16537
• Protein name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon)
• Protein function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment.
• PDB: 8UWB
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01603	B56	48 → 453	Protein phosphatase 2A regulatory B subunit (B56 family)	Family

• Sequence:

  MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
  ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
  CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
  VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
  LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
  PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
  ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
  MFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT

• Sequence length: 467

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BRONCHIAL DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BRONCHITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHROMOSOMAL INSTABILITY	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GALLBLADDER NEOPLASM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Carcinoma	Breast Carcinoma	BEFREE	19890961		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	19890961	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	24204789		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	24448818		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	37175484	Associate	★☆☆☆☆ Found in Text Mining only
Diffuse Large B-Cell Lymphoma	Diffuse Lymphoma	BEFREE	27720936		★☆☆☆☆ Found in Text Mining only
Fragile X Syndrome	Fragile X Syndrome	BEFREE	30160796		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	28720530		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	28720530		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	24204789	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	19890961		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	24204789		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	24997345		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	19773383, 24997345		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	19773383, 24997345		★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	BEFREE	19773383, 20807766		★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	24997345		★☆☆☆☆ Found in Text Mining only