POU6F1 (POU class 6 homeobox 1)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 5463
• Gene name: POU class 6 homeobox 1
• Gene symbol: POU6F1
• Synonyms (NCBI Gene): BRN5, MPOU, TCFB1
• Chromosome: 12
• Chromosome location: 12q13.13

miRNA Show/Hide all (268)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018056	hsa-miR-335-5p	Microarray	18185580
MIRT721831	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT721830	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT721829	hsa-miR-3183	HITS-CLIP	19536157
MIRT721828	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT721827	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT721826	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT721825	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT721824	hsa-miR-4279	HITS-CLIP	19536157
MIRT721823	hsa-miR-6758-3p	HITS-CLIP	19536157
MIRT721831	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT721830	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT721829	hsa-miR-3183	HITS-CLIP	19536157
MIRT721828	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT721827	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT721826	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT721825	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT721824	hsa-miR-4279	HITS-CLIP	19536157
MIRT721823	hsa-miR-6758-3p	HITS-CLIP	19536157
MIRT1251052	hsa-miR-105	CLIP-seq
MIRT1251053	hsa-miR-122	CLIP-seq
MIRT1251054	hsa-miR-1224-3p	CLIP-seq
MIRT1251055	hsa-miR-1228	CLIP-seq
MIRT1251056	hsa-miR-1234	CLIP-seq
MIRT1251057	hsa-miR-1246	CLIP-seq
MIRT1251058	hsa-miR-1273f	CLIP-seq
MIRT1251059	hsa-miR-1303	CLIP-seq
MIRT1251060	hsa-miR-1323	CLIP-seq
MIRT1251061	hsa-miR-140-3p	CLIP-seq
MIRT1251062	hsa-miR-142-3p	CLIP-seq
MIRT1251063	hsa-miR-143	CLIP-seq
MIRT1251064	hsa-miR-147	CLIP-seq
MIRT1251065	hsa-miR-1827	CLIP-seq
MIRT1251066	hsa-miR-197	CLIP-seq
MIRT1251067	hsa-miR-200b	CLIP-seq
MIRT1251068	hsa-miR-200c	CLIP-seq
MIRT1251069	hsa-miR-2115	CLIP-seq
MIRT1251070	hsa-miR-297	CLIP-seq
MIRT1251071	hsa-miR-3135b	CLIP-seq
MIRT1251072	hsa-miR-3149	CLIP-seq
MIRT1251073	hsa-miR-3155	CLIP-seq
MIRT1251074	hsa-miR-3155b	CLIP-seq
MIRT1251075	hsa-miR-3187-3p	CLIP-seq
MIRT1251076	hsa-miR-3194-3p	CLIP-seq
MIRT1251077	hsa-miR-342-5p	CLIP-seq
MIRT1251078	hsa-miR-3612	CLIP-seq
MIRT1251079	hsa-miR-3652	CLIP-seq
MIRT1251080	hsa-miR-3653	CLIP-seq
MIRT1251081	hsa-miR-3658	CLIP-seq
MIRT1251082	hsa-miR-3661	CLIP-seq
MIRT1251083	hsa-miR-3663-3p	CLIP-seq
MIRT1251084	hsa-miR-3663-5p	CLIP-seq
MIRT1251085	hsa-miR-3667-3p	CLIP-seq
MIRT1251086	hsa-miR-3672	CLIP-seq
MIRT1251087	hsa-miR-3692	CLIP-seq
MIRT1251088	hsa-miR-3911	CLIP-seq
MIRT1251089	hsa-miR-411	CLIP-seq
MIRT1251090	hsa-miR-429	CLIP-seq
MIRT1251091	hsa-miR-431	CLIP-seq
MIRT1251092	hsa-miR-4430	CLIP-seq
MIRT1251093	hsa-miR-4443	CLIP-seq
MIRT1251094	hsa-miR-4454	CLIP-seq
MIRT1251095	hsa-miR-452	CLIP-seq
MIRT1251096	hsa-miR-4529-5p	CLIP-seq
MIRT1251097	hsa-miR-4648	CLIP-seq
MIRT1251098	hsa-miR-4651	CLIP-seq
MIRT1251099	hsa-miR-4654	CLIP-seq
MIRT1251100	hsa-miR-4664-5p	CLIP-seq
MIRT1251101	hsa-miR-4676-3p	CLIP-seq
MIRT1251102	hsa-miR-4708-5p	CLIP-seq
MIRT1251103	hsa-miR-4716-5p	CLIP-seq
MIRT1251104	hsa-miR-4735-5p	CLIP-seq
MIRT1251105	hsa-miR-4756-3p	CLIP-seq
MIRT1251106	hsa-miR-4769-5p	CLIP-seq
MIRT1251107	hsa-miR-4770	CLIP-seq
MIRT1251108	hsa-miR-4775	CLIP-seq
MIRT1251109	hsa-miR-4781-3p	CLIP-seq
MIRT1251110	hsa-miR-4783-5p	CLIP-seq
MIRT1251111	hsa-miR-4786-5p	CLIP-seq
MIRT1251112	hsa-miR-4792	CLIP-seq
MIRT1251113	hsa-miR-4794	CLIP-seq
MIRT1251114	hsa-miR-4802-3p	CLIP-seq
MIRT1251115	hsa-miR-483-5p	CLIP-seq
MIRT1251116	hsa-miR-484	CLIP-seq
MIRT1251117	hsa-miR-490-5p	CLIP-seq
MIRT1251118	hsa-miR-495	CLIP-seq
MIRT1251119	hsa-miR-5096	CLIP-seq
MIRT1251120	hsa-miR-516a-3p	CLIP-seq
MIRT1251121	hsa-miR-548o	CLIP-seq
MIRT1251122	hsa-miR-567	CLIP-seq
MIRT1251123	hsa-miR-576-3p	CLIP-seq
MIRT1251124	hsa-miR-583	CLIP-seq
MIRT1251125	hsa-miR-590-3p	CLIP-seq
MIRT1251126	hsa-miR-608	CLIP-seq
MIRT1251127	hsa-miR-631	CLIP-seq
MIRT1251128	hsa-miR-644	CLIP-seq
MIRT1251129	hsa-miR-648	CLIP-seq
MIRT1251130	hsa-miR-650	CLIP-seq
MIRT1251131	hsa-miR-769-5p	CLIP-seq
MIRT1251132	hsa-miR-924	CLIP-seq
MIRT1251133	hsa-miR-933	CLIP-seq
MIRT1251066	hsa-miR-197	CLIP-seq
MIRT1251073	hsa-miR-3155	CLIP-seq
MIRT1251074	hsa-miR-3155b	CLIP-seq
MIRT1251084	hsa-miR-3663-5p	CLIP-seq
MIRT1251089	hsa-miR-411	CLIP-seq
MIRT1251103	hsa-miR-4716-5p	CLIP-seq
MIRT1251109	hsa-miR-4781-3p	CLIP-seq
MIRT1251115	hsa-miR-483-5p	CLIP-seq
MIRT1251116	hsa-miR-484	CLIP-seq
MIRT1251119	hsa-miR-5096	CLIP-seq
MIRT1251053	hsa-miR-122	CLIP-seq
MIRT1251055	hsa-miR-1228	CLIP-seq
MIRT1251061	hsa-miR-140-3p	CLIP-seq
MIRT1251062	hsa-miR-142-3p	CLIP-seq
MIRT1251066	hsa-miR-197	CLIP-seq
MIRT1251071	hsa-miR-3135b	CLIP-seq
MIRT1251072	hsa-miR-3149	CLIP-seq
MIRT1251073	hsa-miR-3155	CLIP-seq
MIRT1251074	hsa-miR-3155b	CLIP-seq
MIRT1251079	hsa-miR-3652	CLIP-seq
MIRT1251084	hsa-miR-3663-5p	CLIP-seq
MIRT1251087	hsa-miR-3692	CLIP-seq
MIRT1251089	hsa-miR-411	CLIP-seq
MIRT1251092	hsa-miR-4430	CLIP-seq
MIRT1251103	hsa-miR-4716-5p	CLIP-seq
MIRT1251104	hsa-miR-4735-5p	CLIP-seq
MIRT1251108	hsa-miR-4775	CLIP-seq
MIRT1251109	hsa-miR-4781-3p	CLIP-seq
MIRT1251113	hsa-miR-4794	CLIP-seq
MIRT1251115	hsa-miR-483-5p	CLIP-seq
MIRT1251116	hsa-miR-484	CLIP-seq
MIRT2074094	hsa-miR-499-3p	CLIP-seq
MIRT2074095	hsa-miR-499a-3p	CLIP-seq
MIRT1251119	hsa-miR-5096	CLIP-seq
MIRT1251125	hsa-miR-590-3p	CLIP-seq
MIRT1251129	hsa-miR-648	CLIP-seq
MIRT2301105	hsa-miR-133a	CLIP-seq
MIRT2301106	hsa-miR-133b	CLIP-seq
MIRT1251066	hsa-miR-197	CLIP-seq
MIRT2301107	hsa-miR-2467-5p	CLIP-seq
MIRT1251073	hsa-miR-3155	CLIP-seq
MIRT1251074	hsa-miR-3155b	CLIP-seq
MIRT2301108	hsa-miR-3188	CLIP-seq
MIRT1251084	hsa-miR-3663-5p	CLIP-seq
MIRT2301109	hsa-miR-3975	CLIP-seq
MIRT1251089	hsa-miR-411	CLIP-seq
MIRT2301110	hsa-miR-4316	CLIP-seq
MIRT2301111	hsa-miR-4317	CLIP-seq
MIRT2301112	hsa-miR-4659a-3p	CLIP-seq
MIRT2301113	hsa-miR-4659b-3p	CLIP-seq
MIRT2301114	hsa-miR-4695-3p	CLIP-seq
MIRT1251103	hsa-miR-4716-5p	CLIP-seq
MIRT2301115	hsa-miR-4722-3p	CLIP-seq
MIRT1251109	hsa-miR-4781-3p	CLIP-seq
MIRT1251115	hsa-miR-483-5p	CLIP-seq
MIRT1251116	hsa-miR-484	CLIP-seq
MIRT2301116	hsa-miR-485-5p	CLIP-seq
MIRT1251119	hsa-miR-5096	CLIP-seq
MIRT2301117	hsa-miR-561	CLIP-seq
MIRT1251066	hsa-miR-197	CLIP-seq
MIRT2392862	hsa-miR-2355-3p	CLIP-seq
MIRT1251073	hsa-miR-3155	CLIP-seq
MIRT1251074	hsa-miR-3155b	CLIP-seq
MIRT1251084	hsa-miR-3663-5p	CLIP-seq
MIRT2392863	hsa-miR-3918	CLIP-seq
MIRT2392864	hsa-miR-4685-5p	CLIP-seq
MIRT1251103	hsa-miR-4716-5p	CLIP-seq
MIRT1251109	hsa-miR-4781-3p	CLIP-seq
MIRT1251115	hsa-miR-483-5p	CLIP-seq
MIRT1251116	hsa-miR-484	CLIP-seq
MIRT1251119	hsa-miR-5096	CLIP-seq
MIRT2432222	hsa-miR-331-3p	CLIP-seq
MIRT2432223	hsa-miR-4694-5p	CLIP-seq
MIRT1251055	hsa-miR-1228	CLIP-seq
MIRT1251061	hsa-miR-140-3p	CLIP-seq
MIRT2456953	hsa-miR-15a	CLIP-seq
MIRT2456954	hsa-miR-15b	CLIP-seq
MIRT2456955	hsa-miR-16	CLIP-seq
MIRT2456956	hsa-miR-1915	CLIP-seq
MIRT2456957	hsa-miR-195	CLIP-seq
MIRT1251066	hsa-miR-197	CLIP-seq
MIRT1251071	hsa-miR-3135b	CLIP-seq
MIRT1251072	hsa-miR-3149	CLIP-seq
MIRT2456958	hsa-miR-3150b-3p	CLIP-seq
MIRT2456959	hsa-miR-3190	CLIP-seq
MIRT1251076	hsa-miR-3194-3p	CLIP-seq
MIRT1251079	hsa-miR-3652	CLIP-seq
MIRT1251089	hsa-miR-411	CLIP-seq
MIRT2456960	hsa-miR-424	CLIP-seq
MIRT2456961	hsa-miR-4303	CLIP-seq
MIRT1251091	hsa-miR-431	CLIP-seq
MIRT2456962	hsa-miR-4323	CLIP-seq
MIRT1251092	hsa-miR-4430	CLIP-seq
MIRT2456963	hsa-miR-4468	CLIP-seq
MIRT2456964	hsa-miR-4683	CLIP-seq
MIRT1251103	hsa-miR-4716-5p	CLIP-seq
MIRT1251104	hsa-miR-4735-5p	CLIP-seq
MIRT1251108	hsa-miR-4775	CLIP-seq
MIRT2456965	hsa-miR-4784	CLIP-seq
MIRT1251111	hsa-miR-4786-5p	CLIP-seq
MIRT1251113	hsa-miR-4794	CLIP-seq
MIRT1251115	hsa-miR-483-5p	CLIP-seq
MIRT2456966	hsa-miR-497	CLIP-seq
MIRT2074094	hsa-miR-499-3p	CLIP-seq
MIRT2074095	hsa-miR-499a-3p	CLIP-seq
MIRT1251119	hsa-miR-5096	CLIP-seq
MIRT1251125	hsa-miR-590-3p	CLIP-seq
MIRT2456967	hsa-miR-7	CLIP-seq
MIRT1251131	hsa-miR-769-5p	CLIP-seq
MIRT1251132	hsa-miR-924	CLIP-seq
MIRT1251055	hsa-miR-1228	CLIP-seq
MIRT1251061	hsa-miR-140-3p	CLIP-seq
MIRT2456953	hsa-miR-15a	CLIP-seq
MIRT2456954	hsa-miR-15b	CLIP-seq
MIRT2456955	hsa-miR-16	CLIP-seq
MIRT2456957	hsa-miR-195	CLIP-seq
MIRT1251066	hsa-miR-197	CLIP-seq
MIRT1251072	hsa-miR-3149	CLIP-seq
MIRT1251089	hsa-miR-411	CLIP-seq
MIRT2456960	hsa-miR-424	CLIP-seq
MIRT2456961	hsa-miR-4303	CLIP-seq
MIRT2456963	hsa-miR-4468	CLIP-seq
MIRT1251103	hsa-miR-4716-5p	CLIP-seq
MIRT1251104	hsa-miR-4735-5p	CLIP-seq
MIRT1251108	hsa-miR-4775	CLIP-seq
MIRT1251109	hsa-miR-4781-3p	CLIP-seq
MIRT1251113	hsa-miR-4794	CLIP-seq
MIRT1251115	hsa-miR-483-5p	CLIP-seq
MIRT2456966	hsa-miR-497	CLIP-seq
MIRT2074094	hsa-miR-499-3p	CLIP-seq
MIRT2074095	hsa-miR-499a-3p	CLIP-seq
MIRT1251119	hsa-miR-5096	CLIP-seq
MIRT1251125	hsa-miR-590-3p	CLIP-seq
MIRT1251055	hsa-miR-1228	CLIP-seq
MIRT1251061	hsa-miR-140-3p	CLIP-seq
MIRT1251066	hsa-miR-197	CLIP-seq
MIRT1251071	hsa-miR-3135b	CLIP-seq
MIRT1251072	hsa-miR-3149	CLIP-seq
MIRT1251076	hsa-miR-3194-3p	CLIP-seq
MIRT1251079	hsa-miR-3652	CLIP-seq
MIRT1251089	hsa-miR-411	CLIP-seq
MIRT1251091	hsa-miR-431	CLIP-seq
MIRT1251092	hsa-miR-4430	CLIP-seq
MIRT1251103	hsa-miR-4716-5p	CLIP-seq
MIRT1251104	hsa-miR-4735-5p	CLIP-seq
MIRT1251108	hsa-miR-4775	CLIP-seq
MIRT1251109	hsa-miR-4781-3p	CLIP-seq
MIRT1251111	hsa-miR-4786-5p	CLIP-seq
MIRT1251113	hsa-miR-4794	CLIP-seq
MIRT1251115	hsa-miR-483-5p	CLIP-seq
MIRT1251119	hsa-miR-5096	CLIP-seq
MIRT1251125	hsa-miR-590-3p	CLIP-seq
MIRT1251131	hsa-miR-769-5p	CLIP-seq
MIRT1251132	hsa-miR-924	CLIP-seq
MIRT1251055	hsa-miR-1228	CLIP-seq
MIRT1251061	hsa-miR-140-3p	CLIP-seq
MIRT1251066	hsa-miR-197	CLIP-seq
MIRT1251072	hsa-miR-3149	CLIP-seq
MIRT1251089	hsa-miR-411	CLIP-seq
MIRT1251103	hsa-miR-4716-5p	CLIP-seq
MIRT1251104	hsa-miR-4735-5p	CLIP-seq
MIRT1251108	hsa-miR-4775	CLIP-seq
MIRT1251109	hsa-miR-4781-3p	CLIP-seq
MIRT1251113	hsa-miR-4794	CLIP-seq
MIRT1251115	hsa-miR-483-5p	CLIP-seq
MIRT1251119	hsa-miR-5096	CLIP-seq
MIRT1251125	hsa-miR-590-3p	CLIP-seq

Gene ontology (GO) Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	8645295
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	8645295
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0003700	Function	DNA-binding transcription factor activity	TAS	7908264
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007417	Process	Central nervous system development	IEA
GO:0007420	Process	Brain development	TAS	7908264
GO:0007507	Process	Heart development	TAS	7908264
GO:0007517	Process	Muscle organ development	TAS	7908264
GO:0043565	Function	Sequence-specific DNA binding	IDA	8645295
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 618043
• HGNC: 9224
• e!Ensembl: ENSG00000184271

Protein

• UniProt ID: Q14863
• Protein name: POU domain, class 6, transcription factor 1 (Brain-specific homeobox/POU domain protein 5) (Brain-5) (Brn-5) (mPOU homeobox protein)
• Protein function: Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').
• PDB: 3D1N
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00046	Homeodomain	235 → 291	Homeodomain	Domain
  PF00157	Pou	142 → 213	Pou domain - N-terminal to homeobox domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: In the embryo, expressed exclusively in the developing brain, whereas in the adult its expression is restricted to brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in specific cell layers of
• Sequence:

  MPGISSQILTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLA
  SSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCS
  ETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAY
  SQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTS
  FTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQI
  P

• Sequence length: 301

Related Genes

No strongly related genes found yet for POU6F1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to POU6F1.