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Gene Gene information from NCBI Gene database.
Entrez ID 26073
Gene name DNA polymerase delta interacting protein 2
Gene symbol POLDIP2
Synonyms (NCBI Gene)
PDIP38p38
Chromosome 17
Chromosome location 17q11.2
Summary This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions. Alternative splic
miRNA miRNA information provided by mirtarbase database.
487 Show/Hide all (487)
miRTarBase ID miRNA Experiments Reference
MIRT031941 hsa-miR-16-5p Proteomics 18668040
MIRT566367 hsa-miR-107 PAR-CLIP 20371350
MIRT566366 hsa-miR-103a-3p PAR-CLIP 20371350
MIRT566365 hsa-miR-148b-5p PAR-CLIP 20371350
MIRT566364 hsa-miR-6874-3p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
26 Show/Hide all (26)
GO ID Ontology Definition Evidence Reference
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 16428295, 21516116, 24191025, 25416956, 27499296, 32296183, 33961781
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IDA 16428295
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611519 23781 ENSG00000004142
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y2S7
Protein name Polymerase delta-interacting protein 2 (38 kDa DNA polymerase delta interaction protein) (p38)
Protein function Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites (PubMed:24191025). May act by stimulating activity of DNA polymerases involved in TLS, such as PRI
PDB 6Z9C , 6ZLX
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04379 DUF525 252 → 338 ApaG domain Family
PF08755 YccV-like 75 → 207 Hemimethylated DNA-binding protein YccV like Domain
Sequence
MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGK
VLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAG
HGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHED
ILPYTSTDQVPIQHELFERFLLYDQTK
APPFVARETLRAWQEKNHPWLELSDVHRETTEN
IRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRG
VVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFER
PDGSHFDVRIPPFSLESNKDEK
TPPSGLHW
Sequence length 368
Interactions View interactions