POLDIP2 (DNA polymerase delta interacting protein 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 26073 |
| Gene name | DNA polymerase delta interacting protein 2 |
| Gene symbol | POLDIP2 |
| Synonyms (NCBI Gene) |
PDIP38p38
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| Chromosome | 17 |
| Chromosome location | 17q11.2 |
| Summary | This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions. Alternative splic |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y2S7 | |||||||||||||||
| Protein name | Polymerase delta-interacting protein 2 (38 kDa DNA polymerase delta interaction protein) (p38) | |||||||||||||||
| Protein function | Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites (PubMed:24191025). May act by stimulating activity of DNA polymerases involved in TLS, such as PRI | |||||||||||||||
| PDB | 6Z9C , 6ZLX | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 368 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Related Genes
Genes most often co-reported with POLDIP2 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to POLDIP2 (see Related Genes above), that are NOT already directly curated for POLDIP2 itself -- a lead worth checking, not a confirmed association.
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