POFUT4 (protein O-fucosyltransferase 4)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 170384 |
| Gene name | Protein O-fucosyltransferase 4 |
| Gene symbol | POFUT4 |
| Synonyms (NCBI Gene) |
FUCTXIFUT11
|
| Chromosome | 10 |
| Chromosome location | 10q22.2 |
|
miRNA
miRNA information provided by mirtarbase database.
404
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
19
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
||||||||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q495W5 | |||||||||||||||
| Protein name | GDP-fucose protein O-fucosyltransferase 4 (EC 2.4.1.221) (Alpha-(1,3)-fucosyltransferase 11) (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) | |||||||||||||||
| Protein function | Protein O-fucosyltransferase that specifically catalyzes O-fucosylation of serine or threonine residues in EMI domains of target proteins, such as MMRN1, MMRN2 and EMID1 (PubMed:39775168). Attaches fucose through an O-glycosidic linkage (PubMed: | |||||||||||||||
| Family and domains |
Pfam
|
|||||||||||||||
| Sequence |
|
|||||||||||||||
| Sequence length | 492 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||
|
|||
|
Related Genes
Genes most often co-reported with POFUT4 across shared curated disease and pathway associations.
0
|
|
|
Diseases Linked via Similar Genes
Diseases curated for genes most similar to POFUT4 (see Related Genes above), that are NOT already directly curated for POFUT4 itself -- a lead worth checking, not a confirmed association.
0
|
|