POFUT3 (protein O-fucosyltransferase 3)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 84750
• Gene name: Protein O-fucosyltransferase 3
• Gene symbol: POFUT3
• Synonyms (NCBI Gene): FUCTX, FUT10
• Chromosome: 8
• Chromosome location: 8p12

miRNA Show/Hide all (265)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025374	hsa-miR-34a-5p	Sequencing	20371350
MIRT051863	hsa-let-7c-5p	CLASH	23622248
MIRT458299	hsa-miR-548m	PAR-CLIP	23592263
MIRT458298	hsa-miR-3609	PAR-CLIP	23592263
MIRT458297	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT458296	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT458295	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT458294	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT458293	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT458292	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT458291	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT458290	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT458289	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT458288	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT458287	hsa-miR-183-5p	PAR-CLIP	23592263
MIRT458286	hsa-miR-4698	PAR-CLIP	23592263
MIRT458285	hsa-miR-5681a	PAR-CLIP	23592263
MIRT458284	hsa-miR-6730-5p	PAR-CLIP	23592263
MIRT458283	hsa-miR-4524a-3p	PAR-CLIP	23592263
MIRT458282	hsa-let-7a-5p	PAR-CLIP	23592263
MIRT458281	hsa-let-7b-5p	PAR-CLIP	23592263
MIRT051863	hsa-let-7c-5p	PAR-CLIP	23592263
MIRT458280	hsa-let-7d-5p	PAR-CLIP	23592263
MIRT458279	hsa-let-7e-5p	PAR-CLIP	23592263
MIRT458278	hsa-let-7f-5p	PAR-CLIP	23592263
MIRT458277	hsa-let-7g-5p	PAR-CLIP	23592263
MIRT458276	hsa-let-7i-5p	PAR-CLIP	23592263
MIRT458274	hsa-miR-4458	PAR-CLIP	23592263
MIRT458275	hsa-miR-4500	PAR-CLIP	23592263
MIRT458273	hsa-miR-98-5p	PAR-CLIP	23592263
MIRT458272	hsa-miR-202-3p	PAR-CLIP	23592263
MIRT458271	hsa-miR-1468-3p	PAR-CLIP	23592263
MIRT458269	hsa-miR-4470	PAR-CLIP	23592263
MIRT458270	hsa-miR-4713-3p	PAR-CLIP	23592263
MIRT458268	hsa-miR-638	PAR-CLIP	23592263
MIRT458267	hsa-miR-505-3p	PAR-CLIP	23592263
MIRT458266	hsa-miR-488-3p	PAR-CLIP	23592263
MIRT458265	hsa-miR-450b-3p	PAR-CLIP	23592263
MIRT458264	hsa-miR-769-3p	PAR-CLIP	23592263
MIRT458263	hsa-miR-3138	PAR-CLIP	23592263
MIRT446715	hsa-miR-548at-5p	PAR-CLIP	22100165
MIRT446714	hsa-miR-561-3p	PAR-CLIP	22100165
MIRT446713	hsa-miR-148a-5p	PAR-CLIP	22100165
MIRT446712	hsa-miR-5584-3p	PAR-CLIP	22100165
MIRT446711	hsa-miR-142-5p	PAR-CLIP	22100165
MIRT446710	hsa-miR-5590-3p	PAR-CLIP	22100165
MIRT446709	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT446708	hsa-miR-371b-5p	PAR-CLIP	22100165
MIRT446707	hsa-miR-373-5p	PAR-CLIP	22100165
MIRT446706	hsa-miR-616-5p	PAR-CLIP	22100165
MIRT450007	hsa-miR-371a-5p	PAR-CLIP	22100165
MIRT450006	hsa-miR-372-5p	PAR-CLIP	22100165
MIRT446705	hsa-miR-4635	PAR-CLIP	22100165
MIRT446704	hsa-miR-570-3p	PAR-CLIP	22100165
MIRT446703	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446715	hsa-miR-548at-5p	PAR-CLIP	22100165
MIRT446714	hsa-miR-561-3p	PAR-CLIP	22100165
MIRT446713	hsa-miR-148a-5p	PAR-CLIP	22100165
MIRT446712	hsa-miR-5584-3p	PAR-CLIP	22100165
MIRT446711	hsa-miR-142-5p	PAR-CLIP	22100165
MIRT446710	hsa-miR-5590-3p	PAR-CLIP	22100165
MIRT446709	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT446708	hsa-miR-371b-5p	PAR-CLIP	22100165
MIRT446707	hsa-miR-373-5p	PAR-CLIP	22100165
MIRT446706	hsa-miR-616-5p	PAR-CLIP	22100165
MIRT446705	hsa-miR-4635	PAR-CLIP	22100165
MIRT446704	hsa-miR-570-3p	PAR-CLIP	22100165
MIRT446703	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT727631	hsa-miR-92a-3p	HITS-CLIP	22473208
MIRT727630	hsa-miR-92b-3p	HITS-CLIP	22473208
MIRT727629	hsa-miR-32-5p	HITS-CLIP	22473208
MIRT458282	hsa-let-7a-5p	PAR-CLIP	26701625
MIRT458282	hsa-let-7a-5p	PAR-CLIP	26701625
MIRT458281	hsa-let-7b-5p	PAR-CLIP	26701625
MIRT458281	hsa-let-7b-5p	PAR-CLIP	26701625
MIRT051863	hsa-let-7c-5p	PAR-CLIP	26701625
MIRT051863	hsa-let-7c-5p	PAR-CLIP	26701625
MIRT458280	hsa-let-7d-5p	PAR-CLIP	26701625
MIRT458280	hsa-let-7d-5p	PAR-CLIP	26701625
MIRT458279	hsa-let-7e-5p	PAR-CLIP	26701625
MIRT458279	hsa-let-7e-5p	PAR-CLIP	26701625
MIRT458278	hsa-let-7f-5p	PAR-CLIP	26701625
MIRT458278	hsa-let-7f-5p	PAR-CLIP	26701625
MIRT458277	hsa-let-7g-5p	PAR-CLIP	26701625
MIRT458277	hsa-let-7g-5p	PAR-CLIP	26701625
MIRT458276	hsa-let-7i-5p	PAR-CLIP	26701625
MIRT458276	hsa-let-7i-5p	PAR-CLIP	26701625
MIRT458296	hsa-miR-106a-5p	PAR-CLIP	26701625
MIRT458296	hsa-miR-106a-5p	PAR-CLIP	26701625
MIRT458295	hsa-miR-106b-5p	PAR-CLIP	26701625
MIRT458295	hsa-miR-106b-5p	PAR-CLIP	26701625
MIRT458271	hsa-miR-1468-3p	PAR-CLIP	26701625
MIRT458271	hsa-miR-1468-3p	PAR-CLIP	26701625
MIRT458294	hsa-miR-17-5p	PAR-CLIP	26701625
MIRT458294	hsa-miR-17-5p	PAR-CLIP	26701625
MIRT458287	hsa-miR-183-5p	PAR-CLIP	26701625
MIRT458287	hsa-miR-183-5p	PAR-CLIP	26701625
MIRT458272	hsa-miR-202-3p	PAR-CLIP	26701625
MIRT458272	hsa-miR-202-3p	PAR-CLIP	26701625
MIRT458293	hsa-miR-20a-5p	PAR-CLIP	26701625
MIRT458293	hsa-miR-20a-5p	PAR-CLIP	26701625
MIRT458292	hsa-miR-20b-5p	PAR-CLIP	26701625
MIRT458292	hsa-miR-20b-5p	PAR-CLIP	26701625
MIRT458263	hsa-miR-3138	PAR-CLIP	26701625
MIRT458263	hsa-miR-3138	PAR-CLIP	26701625
MIRT458298	hsa-miR-3609	PAR-CLIP	26701625
MIRT458298	hsa-miR-3609	PAR-CLIP	26701625
MIRT458274	hsa-miR-4458	PAR-CLIP	26701625
MIRT458274	hsa-miR-4458	PAR-CLIP	26701625
MIRT458269	hsa-miR-4470	PAR-CLIP	26701625
MIRT458269	hsa-miR-4470	PAR-CLIP	26701625
MIRT458275	hsa-miR-4500	PAR-CLIP	26701625
MIRT458275	hsa-miR-4500	PAR-CLIP	26701625
MIRT458283	hsa-miR-4524a-3p	PAR-CLIP	26701625
MIRT458283	hsa-miR-4524a-3p	PAR-CLIP	26701625
MIRT458288	hsa-miR-4796-3p	PAR-CLIP	26701625
MIRT458288	hsa-miR-4796-3p	PAR-CLIP	26701625
MIRT458266	hsa-miR-488-3p	PAR-CLIP	26701625
MIRT458266	hsa-miR-488-3p	PAR-CLIP	26701625
MIRT458291	hsa-miR-519d-3p	PAR-CLIP	26701625
MIRT458291	hsa-miR-519d-3p	PAR-CLIP	26701625
MIRT458290	hsa-miR-526b-3p	PAR-CLIP	26701625
MIRT458290	hsa-miR-526b-3p	PAR-CLIP	26701625
MIRT458297	hsa-miR-548ah-5p	PAR-CLIP	26701625
MIRT458297	hsa-miR-548ah-5p	PAR-CLIP	26701625
MIRT458299	hsa-miR-548m	PAR-CLIP	26701625
MIRT458299	hsa-miR-548m	PAR-CLIP	26701625
MIRT458285	hsa-miR-5681a	PAR-CLIP	26701625
MIRT458285	hsa-miR-5681a	PAR-CLIP	26701625
MIRT458284	hsa-miR-6730-5p	PAR-CLIP	26701625
MIRT458284	hsa-miR-6730-5p	PAR-CLIP	26701625
MIRT458289	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT458289	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT458273	hsa-miR-98-5p	PAR-CLIP	26701625
MIRT458273	hsa-miR-98-5p	PAR-CLIP	26701625
MIRT458299	hsa-miR-548m	PAR-CLIP	23592263
MIRT458298	hsa-miR-3609	PAR-CLIP	23592263
MIRT458297	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT458296	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT458295	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT458294	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT458293	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT458292	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT458291	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT458290	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT458289	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT458288	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT458287	hsa-miR-183-5p	PAR-CLIP	23592263
MIRT458286	hsa-miR-4698	PAR-CLIP	23592263
MIRT458285	hsa-miR-5681a	PAR-CLIP	23592263
MIRT458284	hsa-miR-6730-5p	PAR-CLIP	23592263
MIRT458283	hsa-miR-4524a-3p	PAR-CLIP	23592263
MIRT458282	hsa-let-7a-5p	PAR-CLIP	23592263
MIRT458281	hsa-let-7b-5p	PAR-CLIP	23592263
MIRT051863	hsa-let-7c-5p	PAR-CLIP	23592263
MIRT458280	hsa-let-7d-5p	PAR-CLIP	23592263
MIRT458279	hsa-let-7e-5p	PAR-CLIP	23592263
MIRT458278	hsa-let-7f-5p	PAR-CLIP	23592263
MIRT458277	hsa-let-7g-5p	PAR-CLIP	23592263
MIRT458276	hsa-let-7i-5p	PAR-CLIP	23592263
MIRT458274	hsa-miR-4458	PAR-CLIP	23592263
MIRT458275	hsa-miR-4500	PAR-CLIP	23592263
MIRT458273	hsa-miR-98-5p	PAR-CLIP	23592263
MIRT458272	hsa-miR-202-3p	PAR-CLIP	23592263
MIRT458271	hsa-miR-1468-3p	PAR-CLIP	23592263
MIRT458269	hsa-miR-4470	PAR-CLIP	23592263
MIRT458270	hsa-miR-4713-3p	PAR-CLIP	23592263
MIRT458268	hsa-miR-638	PAR-CLIP	23592263
MIRT458267	hsa-miR-505-3p	PAR-CLIP	23592263
MIRT458266	hsa-miR-488-3p	PAR-CLIP	23592263
MIRT458265	hsa-miR-450b-3p	PAR-CLIP	23592263
MIRT458264	hsa-miR-769-3p	PAR-CLIP	23592263
MIRT458263	hsa-miR-3138	PAR-CLIP	23592263
MIRT446715	hsa-miR-548at-5p	PAR-CLIP	22100165
MIRT446714	hsa-miR-561-3p	PAR-CLIP	22100165
MIRT446713	hsa-miR-148a-5p	PAR-CLIP	22100165
MIRT446712	hsa-miR-5584-3p	PAR-CLIP	22100165
MIRT446711	hsa-miR-142-5p	PAR-CLIP	22100165
MIRT446710	hsa-miR-5590-3p	PAR-CLIP	22100165
MIRT446709	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT446708	hsa-miR-371b-5p	PAR-CLIP	22100165
MIRT446707	hsa-miR-373-5p	PAR-CLIP	22100165
MIRT446706	hsa-miR-616-5p	PAR-CLIP	22100165
MIRT450007	hsa-miR-371a-5p	PAR-CLIP	22100165
MIRT450006	hsa-miR-372-5p	PAR-CLIP	22100165
MIRT446705	hsa-miR-4635	PAR-CLIP	22100165
MIRT446704	hsa-miR-570-3p	PAR-CLIP	22100165
MIRT446703	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446715	hsa-miR-548at-5p	PAR-CLIP	22100165
MIRT446714	hsa-miR-561-3p	PAR-CLIP	22100165
MIRT446713	hsa-miR-148a-5p	PAR-CLIP	22100165
MIRT446712	hsa-miR-5584-3p	PAR-CLIP	22100165
MIRT446711	hsa-miR-142-5p	PAR-CLIP	22100165
MIRT446710	hsa-miR-5590-3p	PAR-CLIP	22100165
MIRT446709	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT446708	hsa-miR-371b-5p	PAR-CLIP	22100165
MIRT446707	hsa-miR-373-5p	PAR-CLIP	22100165
MIRT446706	hsa-miR-616-5p	PAR-CLIP	22100165
MIRT446705	hsa-miR-4635	PAR-CLIP	22100165
MIRT446704	hsa-miR-570-3p	PAR-CLIP	22100165
MIRT446703	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT1006429	hsa-miR-103a	CLIP-seq
MIRT1006430	hsa-miR-107	CLIP-seq
MIRT1006431	hsa-miR-1184	CLIP-seq
MIRT1006432	hsa-miR-1229	CLIP-seq
MIRT1006433	hsa-miR-1253	CLIP-seq
MIRT1006434	hsa-miR-1266	CLIP-seq
MIRT1006435	hsa-miR-1278	CLIP-seq
MIRT1006436	hsa-miR-186	CLIP-seq
MIRT1006437	hsa-miR-1911	CLIP-seq
MIRT1006438	hsa-miR-217	CLIP-seq
MIRT1006439	hsa-miR-2682	CLIP-seq
MIRT1006440	hsa-miR-299-3p	CLIP-seq
MIRT1006441	hsa-miR-3129-3p	CLIP-seq
MIRT1006442	hsa-miR-3133	CLIP-seq
MIRT1006443	hsa-miR-3185	CLIP-seq
MIRT1006444	hsa-miR-342-3p	CLIP-seq
MIRT1006445	hsa-miR-3529	CLIP-seq
MIRT1006446	hsa-miR-365	CLIP-seq
MIRT1006447	hsa-miR-3692	CLIP-seq
MIRT1006448	hsa-miR-3714	CLIP-seq
MIRT1006449	hsa-miR-379	CLIP-seq
MIRT1006450	hsa-miR-3927	CLIP-seq
MIRT1006451	hsa-miR-425	CLIP-seq
MIRT1006452	hsa-miR-4279	CLIP-seq
MIRT1006453	hsa-miR-4418	CLIP-seq
MIRT1006454	hsa-miR-4434	CLIP-seq
MIRT1006455	hsa-miR-4491	CLIP-seq
MIRT1006456	hsa-miR-449c	CLIP-seq
MIRT1006457	hsa-miR-4516	CLIP-seq
MIRT1006458	hsa-miR-4518	CLIP-seq
MIRT1006459	hsa-miR-4531	CLIP-seq
MIRT1006460	hsa-miR-4657	CLIP-seq
MIRT1006461	hsa-miR-4744	CLIP-seq
MIRT1006462	hsa-miR-4789-3p	CLIP-seq
MIRT1006463	hsa-miR-4802-5p	CLIP-seq
MIRT1006464	hsa-miR-509-3-5p	CLIP-seq
MIRT1006465	hsa-miR-509-5p	CLIP-seq
MIRT1006466	hsa-miR-548ah	CLIP-seq
MIRT1006467	hsa-miR-548an	CLIP-seq
MIRT1006468	hsa-miR-642b	CLIP-seq
MIRT1006469	hsa-miR-659	CLIP-seq
MIRT1006470	hsa-miR-944	CLIP-seq
MIRT1998240	hsa-miR-3671	CLIP-seq
MIRT1998241	hsa-miR-3688-3p	CLIP-seq
MIRT1998242	hsa-miR-4303	CLIP-seq
MIRT1998243	hsa-miR-4649-3p	CLIP-seq
MIRT1998244	hsa-miR-656	CLIP-seq
MIRT1998245	hsa-miR-889	CLIP-seq
MIRT2231835	hsa-miR-3065-3p	CLIP-seq
MIRT2231836	hsa-miR-3198	CLIP-seq
MIRT2231837	hsa-miR-4291	CLIP-seq
MIRT2231838	hsa-miR-4309	CLIP-seq
MIRT2231839	hsa-miR-4653-3p	CLIP-seq
MIRT2388250	hsa-miR-4438	CLIP-seq
MIRT2535863	hsa-miR-199a-5p	CLIP-seq
MIRT2535864	hsa-miR-199b-5p	CLIP-seq
MIRT2535865	hsa-miR-4462	CLIP-seq
MIRT2535866	hsa-miR-4802-3p	CLIP-seq
MIRT2535867	hsa-miR-554	CLIP-seq
MIRT2535868	hsa-miR-7	CLIP-seq
MIRT2535863	hsa-miR-199a-5p	CLIP-seq
MIRT2535864	hsa-miR-199b-5p	CLIP-seq
MIRT2535866	hsa-miR-4802-3p	CLIP-seq
MIRT2535867	hsa-miR-554	CLIP-seq

Gene ontology (GO) Show/Hide all (39)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005764	Component	Lysosome	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA	39775168
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005794	Component	Golgi apparatus	TAS	11698403
GO:0006457	Process	Protein folding	NAS	11698403
GO:0006486	Process	Protein glycosylation	IEA
GO:0006486	Process	Protein glycosylation	TAS	11698403
GO:0006605	Process	Protein targeting	NAS	11698403
GO:0007399	Process	Nervous system development	NAS	11698403
GO:0008417	Function	Fucosyltransferase activity	IDA	19088067
GO:0008417	Function	Fucosyltransferase activity	IEA
GO:0009312	Process	Oligosaccharide biosynthetic process	IEA
GO:0009566	Process	Fertilization	NAS	11698403
GO:0016020	Component	Membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0021799	Process	Cerebral cortex radially oriented cell migration	IEA
GO:0030097	Process	Hemopoiesis	NAS	11698403
GO:0036065	Process	Fucosylation	IBA
GO:0036066	Process	Protein O-linked glycosylation via fucose	IEA
GO:0036071	Process	N-glycan fucosylation	IDA	19088067
GO:0036071	Process	N-glycan fucosylation	IEA
GO:0036445	Process	Neuronal stem cell division	IEA
GO:0036445	Process	Neuronal stem cell division	ISS
GO:0042060	Process	Wound healing	NAS	11698403
GO:0042355	Process	L-fucose catabolic process	NAS	11698403
GO:0046920	Function	Alpha-(1->3)-fucosyltransferase activity	IBA
GO:0046920	Function	Alpha-(1->3)-fucosyltransferase activity	IEA
GO:0046920	Function	Alpha-(1->3)-fucosyltransferase activity	TAS	11698403
GO:0046922	Function	Peptide-O-fucosyltransferase activity	IDA	39775168
GO:0050714	Process	Positive regulation of protein secretion	IDA	39775168
GO:0097150	Process	Neuronal stem cell population maintenance	IEA
GO:0097402	Process	Neuroblast migration	IEA

Other IDs

• MIM: 616931
• HGNC: 19234
• e!Ensembl: ENSG00000172728

Protein

• UniProt ID: Q6P4F1
• Protein name: GDP-fucose protein O-fucosyltransferase 3 (EC 2.4.1.221) (Alpha-(1,3)-fucosyltransferase 10) (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10)
• Protein function: Protein O-fucosyltransferase that specifically catalyzes O-fucosylation of serine or threonine residues in EMI domains of target proteins, such as MMRN1, MMRN2 and EMID1 (PubMed:39775168). Attaches fucose through an O-glycosidic linkage (PubMed:
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00852	Glyco_transf_10	209 → 405	Glycosyltransferase family 10 (fucosyltransferase) C-term	Family
  PF17039	Glyco_tran_10_N	79 → 185	Fucosyltransferase, N-terminal	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in lung, digestive tract, gall bladder, placenta, kidney, uterus and brain. Not detected in spleen, heart, muscle, liver and pancreas. {ECO:0000269|PubMed:19088067}.
• Sequence:

  MVRIQRRKLLASCLCVTATVFLLVTLQVMVELGKFERKEFKSSSLQDGHTKMEEAPTHLN
  SFLKKEGLTFNRKRKWELDSYPIMLWWSPLTGETGRLGQCGADACFFTINRTYLHHHMTK
  AFLFYGTDFNIDSLPLPRKAHHDWAVFHEESPKNNYKLFHKPVITLFNYTATFSRHSHLP
  LTTQYLESIEVLKSLRYLVPLQSKNKLRKRLAPLVYVQSDCDPPSDRDSYVRELMTYIEV
  DSYGECLRNKDLPQQLKNPASMDADGFYRIIAQYKFILAFENAVCDDYITEKFWRPLKLG
  VVPVYYGSPSITDWLPSNKSAILVSEFSHPRELASYIRRLDSDDRLYEAYVEWKLKGEIS
  NQRLLTALRERKWGVQDVNQDNYIDAFECMVCTKVWANIRLQEKGLPPKRWEAEDTHLSC
  PEPTVFAFSPLRTPPLSSLREMWISSFEQSKKEAQALRWLVDRNQNFSSQEFWGLVFKD

• Sequence length: 479

Pathways

Reactome Pathway:

Lewis blood group biosynthesis

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Gastric cancer	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (7)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of colon	Adenocarcinoma Of Colon	BEFREE	8981094		★☆☆☆☆ Found in Text Mining only
Amnesia	Amnesia	GWASCAT_DG	29724592		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	8542587, 9128982		★☆☆☆☆ Found in Text Mining only
Frontotemporal dementia	Frontotemporal dementia	GWASCAT_DG	29724592		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	15666088		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	8542587		★☆☆☆☆ Found in Text Mining only
Memory dysfunction	Memory Disorders	GWASCAT_DG	29724592		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for POFUT3.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to POFUT3.