POFUT2 (protein O-fucosyltransferase 2)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 23275
• Gene name: Protein O-fucosyltransferase 2
• Gene symbol: POFUT2
• Synonyms (NCBI Gene): C21orf80, FUT13
• Chromosome: 21
• Chromosome location: 21q22.3
• Summary: Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombos

miRNA Show/Hide all (311)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018483	hsa-miR-335-5p	Microarray	18185580
MIRT029843	hsa-miR-26b-5p	Microarray	19088304
MIRT039238	hsa-miR-454-3p	CLASH	23622248
MIRT663485	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT663484	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT663483	hsa-miR-5586-3p	HITS-CLIP	23824327
MIRT663482	hsa-miR-759	HITS-CLIP	23824327
MIRT663481	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT663480	hsa-miR-340-3p	HITS-CLIP	23824327
MIRT663479	hsa-miR-6827-3p	HITS-CLIP	23824327
MIRT663478	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT663477	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT663476	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT663475	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT663474	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT663473	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT663472	hsa-miR-612	HITS-CLIP	23824327
MIRT663471	hsa-miR-6860	HITS-CLIP	23824327
MIRT663470	hsa-miR-873-3p	HITS-CLIP	23824327
MIRT663469	hsa-miR-4252	HITS-CLIP	23824327
MIRT663468	hsa-miR-196a-3p	HITS-CLIP	23824327
MIRT663467	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT663466	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT663465	hsa-miR-3672	HITS-CLIP	23824327
MIRT663464	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT663463	hsa-miR-7703	HITS-CLIP	23824327
MIRT488792	hsa-miR-3141	PAR-CLIP	23592263
MIRT488791	hsa-miR-5090	PAR-CLIP	23592263
MIRT488789	hsa-miR-6775-5p	PAR-CLIP	23592263
MIRT488790	hsa-miR-744-5p	PAR-CLIP	23592263
MIRT488788	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT488787	hsa-miR-663a	PAR-CLIP	23592263
MIRT488786	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT488785	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT457372	hsa-miR-6888-5p	PAR-CLIP	23592263
MIRT457371	hsa-miR-4802-5p	PAR-CLIP	23592263
MIRT457370	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT457369	hsa-miR-665	PAR-CLIP	23592263
MIRT457368	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT457367	hsa-miR-1273f	PAR-CLIP	23592263
MIRT457366	hsa-miR-3160-3p	PAR-CLIP	23592263
MIRT457365	hsa-miR-558	PAR-CLIP	23592263
MIRT457364	hsa-miR-4487	PAR-CLIP	23592263
MIRT457363	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT457362	hsa-miR-6086	PAR-CLIP	23592263
MIRT457361	hsa-miR-4534	PAR-CLIP	23592263
MIRT457360	hsa-miR-8082	PAR-CLIP	23592263
MIRT457359	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT457358	hsa-miR-3689d	PAR-CLIP	23592263
MIRT457357	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT457356	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT457355	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT457354	hsa-miR-1273e	PAR-CLIP	23592263
MIRT449867	hsa-miR-548e-5p	PAR-CLIP	22100165
MIRT449866	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT449865	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT449864	hsa-miR-1178-5p	PAR-CLIP	22100165
MIRT449863	hsa-miR-1253	PAR-CLIP	22100165
MIRT449862	hsa-miR-6770-5p	PAR-CLIP	22100165
MIRT449861	hsa-miR-580-3p	PAR-CLIP	22100165
MIRT457354	hsa-miR-1273e	PAR-CLIP	26701625
MIRT457367	hsa-miR-1273f	PAR-CLIP	26701625
MIRT457366	hsa-miR-3160-3p	PAR-CLIP	26701625
MIRT457358	hsa-miR-3689d	PAR-CLIP	26701625
MIRT457363	hsa-miR-377-5p	PAR-CLIP	26701625
MIRT457364	hsa-miR-4487	PAR-CLIP	26701625
MIRT457361	hsa-miR-4534	PAR-CLIP	26701625
MIRT457356	hsa-miR-455-3p	PAR-CLIP	26701625
MIRT457370	hsa-miR-4768-3p	PAR-CLIP	26701625
MIRT457371	hsa-miR-4802-5p	PAR-CLIP	26701625
MIRT457365	hsa-miR-558	PAR-CLIP	26701625
MIRT457362	hsa-miR-6086	PAR-CLIP	26701625
MIRT457359	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT457355	hsa-miR-6516-5p	PAR-CLIP	26701625
MIRT457369	hsa-miR-665	PAR-CLIP	26701625
MIRT457368	hsa-miR-6840-3p	PAR-CLIP	26701625
MIRT457357	hsa-miR-6851-5p	PAR-CLIP	26701625
MIRT457372	hsa-miR-6888-5p	PAR-CLIP	26701625
MIRT457360	hsa-miR-8082	PAR-CLIP	26701625
MIRT457354	hsa-miR-1273e	PAR-CLIP	27292025
MIRT457367	hsa-miR-1273f	PAR-CLIP	27292025
MIRT457366	hsa-miR-3160-3p	PAR-CLIP	27292025
MIRT457358	hsa-miR-3689d	PAR-CLIP	27292025
MIRT457363	hsa-miR-377-5p	PAR-CLIP	27292025
MIRT457364	hsa-miR-4487	PAR-CLIP	27292025
MIRT457361	hsa-miR-4534	PAR-CLIP	27292025
MIRT457356	hsa-miR-455-3p	PAR-CLIP	27292025
MIRT457370	hsa-miR-4768-3p	PAR-CLIP	27292025
MIRT457371	hsa-miR-4802-5p	PAR-CLIP	27292025
MIRT457362	hsa-miR-6086	PAR-CLIP	27292025
MIRT457359	hsa-miR-6499-3p	PAR-CLIP	27292025
MIRT457369	hsa-miR-665	PAR-CLIP	27292025
MIRT457368	hsa-miR-6840-3p	PAR-CLIP	27292025
MIRT457357	hsa-miR-6851-5p	PAR-CLIP	27292025
MIRT457372	hsa-miR-6888-5p	PAR-CLIP	27292025
MIRT457360	hsa-miR-8082	PAR-CLIP	27292025
MIRT663485	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT663484	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT663483	hsa-miR-5586-3p	HITS-CLIP	23824327
MIRT663482	hsa-miR-759	HITS-CLIP	23824327
MIRT663481	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT663480	hsa-miR-340-3p	HITS-CLIP	23824327
MIRT663479	hsa-miR-6827-3p	HITS-CLIP	23824327
MIRT663478	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT663477	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT663476	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT663475	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT663474	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT663473	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT663472	hsa-miR-612	HITS-CLIP	23824327
MIRT663471	hsa-miR-6860	HITS-CLIP	23824327
MIRT663470	hsa-miR-873-3p	HITS-CLIP	23824327
MIRT663469	hsa-miR-4252	HITS-CLIP	23824327
MIRT663468	hsa-miR-196a-3p	HITS-CLIP	23824327
MIRT663467	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT663466	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT663465	hsa-miR-3672	HITS-CLIP	23824327
MIRT663464	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT663463	hsa-miR-7703	HITS-CLIP	23824327
MIRT488792	hsa-miR-3141	PAR-CLIP	23592263
MIRT488791	hsa-miR-5090	PAR-CLIP	23592263
MIRT488789	hsa-miR-6775-5p	PAR-CLIP	23592263
MIRT488790	hsa-miR-744-5p	PAR-CLIP	23592263
MIRT488788	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT488787	hsa-miR-663a	PAR-CLIP	23592263
MIRT488786	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT488785	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT457372	hsa-miR-6888-5p	PAR-CLIP	23592263
MIRT457371	hsa-miR-4802-5p	PAR-CLIP	23592263
MIRT457370	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT457369	hsa-miR-665	PAR-CLIP	23592263
MIRT457368	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT457367	hsa-miR-1273f	PAR-CLIP	23592263
MIRT457366	hsa-miR-3160-3p	PAR-CLIP	23592263
MIRT457365	hsa-miR-558	PAR-CLIP	23592263
MIRT457364	hsa-miR-4487	PAR-CLIP	23592263
MIRT457363	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT457362	hsa-miR-6086	PAR-CLIP	23592263
MIRT457361	hsa-miR-4534	PAR-CLIP	23592263
MIRT457360	hsa-miR-8082	PAR-CLIP	23592263
MIRT457359	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT457358	hsa-miR-3689d	PAR-CLIP	23592263
MIRT457357	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT457356	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT457355	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT457354	hsa-miR-1273e	PAR-CLIP	23592263
MIRT449867	hsa-miR-548e-5p	PAR-CLIP	22100165
MIRT449866	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT449865	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT449864	hsa-miR-1178-5p	PAR-CLIP	22100165
MIRT449863	hsa-miR-1253	PAR-CLIP	22100165
MIRT449862	hsa-miR-6770-5p	PAR-CLIP	22100165
MIRT449861	hsa-miR-580-3p	PAR-CLIP	22100165
MIRT1246706	hsa-miR-103a	CLIP-seq
MIRT1246707	hsa-miR-107	CLIP-seq
MIRT1246708	hsa-miR-10a	CLIP-seq
MIRT1246709	hsa-miR-10b	CLIP-seq
MIRT1246710	hsa-miR-1200	CLIP-seq
MIRT1246711	hsa-miR-1254	CLIP-seq
MIRT1246712	hsa-miR-125a-5p	CLIP-seq
MIRT1246713	hsa-miR-125b	CLIP-seq
MIRT1246714	hsa-miR-1324	CLIP-seq
MIRT1246715	hsa-miR-1343	CLIP-seq
MIRT1246716	hsa-miR-138	CLIP-seq
MIRT1246717	hsa-miR-1469	CLIP-seq
MIRT1246718	hsa-miR-146a	CLIP-seq
MIRT1246719	hsa-miR-146b-5p	CLIP-seq
MIRT1246720	hsa-miR-1587	CLIP-seq
MIRT1246721	hsa-miR-1908	CLIP-seq
MIRT1246722	hsa-miR-203	CLIP-seq
MIRT1246723	hsa-miR-29a	CLIP-seq
MIRT1246724	hsa-miR-29b	CLIP-seq
MIRT1246725	hsa-miR-29c	CLIP-seq
MIRT1246726	hsa-miR-3065-3p	CLIP-seq
MIRT1246727	hsa-miR-3116	CLIP-seq
MIRT1246728	hsa-miR-3120-3p	CLIP-seq
MIRT1246729	hsa-miR-3125	CLIP-seq
MIRT1246730	hsa-miR-3127-5p	CLIP-seq
MIRT1246731	hsa-miR-3144-5p	CLIP-seq
MIRT1246732	hsa-miR-3155	CLIP-seq
MIRT1246733	hsa-miR-3155b	CLIP-seq
MIRT1246734	hsa-miR-3166	CLIP-seq
MIRT1246735	hsa-miR-3180-5p	CLIP-seq
MIRT1246736	hsa-miR-3184	CLIP-seq
MIRT1246737	hsa-miR-3191	CLIP-seq
MIRT1246738	hsa-miR-3194-3p	CLIP-seq
MIRT1246739	hsa-miR-339-5p	CLIP-seq
MIRT1246740	hsa-miR-346	CLIP-seq
MIRT1246741	hsa-miR-3591-3p	CLIP-seq
MIRT1246742	hsa-miR-3621	CLIP-seq
MIRT1246743	hsa-miR-3622b-5p	CLIP-seq
MIRT1246744	hsa-miR-378g	CLIP-seq
MIRT1246745	hsa-miR-3907	CLIP-seq
MIRT1246746	hsa-miR-3913-3p	CLIP-seq
MIRT1246747	hsa-miR-3916	CLIP-seq
MIRT1246748	hsa-miR-3918	CLIP-seq
MIRT1246749	hsa-miR-3922-5p	CLIP-seq
MIRT1246750	hsa-miR-3925-3p	CLIP-seq
MIRT1246751	hsa-miR-411	CLIP-seq
MIRT1246752	hsa-miR-423-5p	CLIP-seq
MIRT1246753	hsa-miR-4253	CLIP-seq
MIRT1246754	hsa-miR-4257	CLIP-seq
MIRT1246755	hsa-miR-4270	CLIP-seq
MIRT1246756	hsa-miR-4283	CLIP-seq
MIRT1246757	hsa-miR-4312	CLIP-seq
MIRT1246758	hsa-miR-4313	CLIP-seq
MIRT1246759	hsa-miR-4319	CLIP-seq
MIRT1246760	hsa-miR-4324	CLIP-seq
MIRT1246761	hsa-miR-4441	CLIP-seq
MIRT1246762	hsa-miR-4456	CLIP-seq
MIRT1246763	hsa-miR-4492	CLIP-seq
MIRT1246764	hsa-miR-4498	CLIP-seq
MIRT1246765	hsa-miR-4527	CLIP-seq
MIRT1246766	hsa-miR-4652-5p	CLIP-seq
MIRT1246767	hsa-miR-4656	CLIP-seq
MIRT1246768	hsa-miR-4675	CLIP-seq
MIRT1246769	hsa-miR-4676-5p	CLIP-seq
MIRT1246770	hsa-miR-4685-5p	CLIP-seq
MIRT1246771	hsa-miR-4688	CLIP-seq
MIRT1246772	hsa-miR-4733-3p	CLIP-seq
MIRT1246773	hsa-miR-4741	CLIP-seq
MIRT1246774	hsa-miR-4755-3p	CLIP-seq
MIRT1246775	hsa-miR-4761-3p	CLIP-seq
MIRT1246776	hsa-miR-4765	CLIP-seq
MIRT1246777	hsa-miR-484	CLIP-seq
MIRT1246778	hsa-miR-491-5p	CLIP-seq
MIRT1246779	hsa-miR-499-3p	CLIP-seq
MIRT1246780	hsa-miR-499a-3p	CLIP-seq
MIRT1246781	hsa-miR-504	CLIP-seq
MIRT1246782	hsa-miR-515-5p	CLIP-seq
MIRT1246783	hsa-miR-516a-3p	CLIP-seq
MIRT1246784	hsa-miR-520a-5p	CLIP-seq
MIRT1246785	hsa-miR-525-5p	CLIP-seq
MIRT1246786	hsa-miR-541	CLIP-seq
MIRT1246787	hsa-miR-544b	CLIP-seq
MIRT1246788	hsa-miR-548q	CLIP-seq
MIRT1246789	hsa-miR-575	CLIP-seq
MIRT1246790	hsa-miR-580	CLIP-seq
MIRT1246791	hsa-miR-603	CLIP-seq
MIRT1246792	hsa-miR-604	CLIP-seq
MIRT1246793	hsa-miR-646	CLIP-seq
MIRT1246794	hsa-miR-654-5p	CLIP-seq
MIRT1246795	hsa-miR-658	CLIP-seq
MIRT1246796	hsa-miR-661	CLIP-seq
MIRT1246797	hsa-miR-663	CLIP-seq
MIRT1246798	hsa-miR-760	CLIP-seq
MIRT1246799	hsa-miR-762	CLIP-seq
MIRT1246800	hsa-miR-766	CLIP-seq
MIRT1246801	hsa-miR-936	CLIP-seq
MIRT1246730	hsa-miR-3127-5p	CLIP-seq
MIRT1246802	hsa-miR-3612	CLIP-seq
MIRT1246803	hsa-miR-3661	CLIP-seq
MIRT1246804	hsa-miR-4254	CLIP-seq
MIRT1246805	hsa-miR-4443	CLIP-seq
MIRT1246790	hsa-miR-580	CLIP-seq
MIRT1246806	hsa-miR-619	CLIP-seq
MIRT1246807	hsa-miR-631	CLIP-seq
MIRT1246808	hsa-miR-650	CLIP-seq
MIRT2072830	hsa-miR-3148	CLIP-seq
MIRT2072831	hsa-miR-1976	CLIP-seq
MIRT2072830	hsa-miR-3148	CLIP-seq
MIRT2072832	hsa-miR-370	CLIP-seq
MIRT2072833	hsa-miR-4690-3p	CLIP-seq
MIRT1246708	hsa-miR-10a	CLIP-seq
MIRT1246709	hsa-miR-10b	CLIP-seq
MIRT2072830	hsa-miR-3148	CLIP-seq
MIRT1246739	hsa-miR-339-5p	CLIP-seq
MIRT1246741	hsa-miR-3591-3p	CLIP-seq
MIRT1246781	hsa-miR-504	CLIP-seq
MIRT1246708	hsa-miR-10a	CLIP-seq
MIRT1246709	hsa-miR-10b	CLIP-seq
MIRT2596671	hsa-miR-1224-5p	CLIP-seq
MIRT1246712	hsa-miR-125a-5p	CLIP-seq
MIRT1246713	hsa-miR-125b	CLIP-seq
MIRT1246730	hsa-miR-3127-5p	CLIP-seq
MIRT2596672	hsa-miR-3130-3p	CLIP-seq
MIRT2596673	hsa-miR-3157-3p	CLIP-seq
MIRT1246739	hsa-miR-339-5p	CLIP-seq
MIRT1246741	hsa-miR-3591-3p	CLIP-seq
MIRT2596674	hsa-miR-3678-3p	CLIP-seq
MIRT1246759	hsa-miR-4319	CLIP-seq
MIRT2596675	hsa-miR-4320	CLIP-seq
MIRT2596676	hsa-miR-4711-3p	CLIP-seq
MIRT2596677	hsa-miR-4751	CLIP-seq
MIRT2596678	hsa-miR-4778-5p	CLIP-seq
MIRT1246781	hsa-miR-504	CLIP-seq
MIRT1246787	hsa-miR-544b	CLIP-seq
MIRT2596679	hsa-miR-874	CLIP-seq
MIRT1246708	hsa-miR-10a	CLIP-seq
MIRT1246709	hsa-miR-10b	CLIP-seq
MIRT2596671	hsa-miR-1224-5p	CLIP-seq
MIRT1246712	hsa-miR-125a-5p	CLIP-seq
MIRT1246713	hsa-miR-125b	CLIP-seq
MIRT2688326	hsa-miR-2964a-5p	CLIP-seq
MIRT1246728	hsa-miR-3120-3p	CLIP-seq
MIRT1246730	hsa-miR-3127-5p	CLIP-seq
MIRT2596672	hsa-miR-3130-3p	CLIP-seq
MIRT2596673	hsa-miR-3157-3p	CLIP-seq
MIRT1246739	hsa-miR-339-5p	CLIP-seq
MIRT1246741	hsa-miR-3591-3p	CLIP-seq
MIRT2596674	hsa-miR-3678-3p	CLIP-seq
MIRT1246759	hsa-miR-4319	CLIP-seq
MIRT2596675	hsa-miR-4320	CLIP-seq
MIRT2596676	hsa-miR-4711-3p	CLIP-seq
MIRT2596677	hsa-miR-4751	CLIP-seq
MIRT2688327	hsa-miR-4761-5p	CLIP-seq
MIRT2596678	hsa-miR-4778-5p	CLIP-seq
MIRT1246781	hsa-miR-504	CLIP-seq
MIRT1246787	hsa-miR-544b	CLIP-seq
MIRT1246790	hsa-miR-580	CLIP-seq
MIRT2596679	hsa-miR-874	CLIP-seq

Gene ontology (GO) Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001707	Process	Mesoderm formation	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005794	Component	Golgi apparatus	IDA	15233996
GO:0005794	Component	Golgi apparatus	IEA
GO:0006004	Process	Fucose metabolic process	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0008417	Function	Fucosyltransferase activity	IEA
GO:0010468	Process	Regulation of gene expression	IEA
GO:0010717	Process	Regulation of epithelial to mesenchymal transition	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0036065	Process	Fucosylation	IEA
GO:0036066	Process	Protein O-linked glycosylation via fucose	IDA	22588082
GO:0036066	Process	Protein O-linked glycosylation via fucose	IEA
GO:0036066	Process	Protein O-linked glycosylation via fucose	TAS
GO:0046922	Function	Peptide-O-fucosyltransferase activity	IBA
GO:0046922	Function	Peptide-O-fucosyltransferase activity	IDA	22588082
GO:0046922	Function	Peptide-O-fucosyltransferase activity	IEA
GO:0046922	Function	Peptide-O-fucosyltransferase activity	TAS
GO:0051046	Process	Regulation of secretion	IDA	17395589
GO:1903334	Process	Positive regulation of protein folding	IMP	25544610

Other IDs

• MIM: 610249
• HGNC: 14683
• e!Ensembl: ENSG00000186866

Protein

• UniProt ID: Q9Y2G5
• Protein name: GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2)
• Protein function: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X-X-S/T-C2 of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cyste
• PDB: 4AP5 , 4AP6
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10250	O-FucT	45 → 400	GDP-fucose protein O-fucosyltransferase	Family

• Tissue specificity: TISSUE SPECIFICITY: Isoform A is expressed in fetal liver and peripheral blood lymphocytes. Isoform B is expressed in spleen, lung, testis, bone marrow, thymus, pancreas, prostate, fetal brain, fetal liver and fetal kidney. Isoform C is expressed in brain
• Sequence:

  MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR
  DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI
  EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYRGWFW
  GYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSM
  VFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIW
  GHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELE
  LYKDGGVAIIDQWICAHARFFIGTSVSTFSFRIHEEREILGLDPKTTYNRFCGDQEKACE
  QPTHWKITY

• Sequence length: 429

Pathways

KEGG Pathway:

Other types of O-glycan biosynthesis

Reactome Pathway:

O-glycosylation of TSR domain-containing proteins

Related Genes

B3GLCT 2 shared pathwaysOther types of O-glycan biosynthesis, O-glycosylation of TSR domain-containing proteins Related via 2 shared pathways including Other types of O-glycan biosynthesis, O-glycosylation of TSR domain-containing proteins.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
B3GLCT	0	[]	2	["Other types of O-glycan biosynthesis","O-glycosylation of TSR domain-containing proteins"]	0	[]

Diseases Linked via Similar Genes

Atrial fibrillation Linked via 1 of 1 related geneB3GLCT Atrophic macular degeneration Linked via 1 of 1 related geneB3GLCT Bipolar disorder Linked via 1 of 1 related geneB3GLCT Cardiovascular disease Linked via 1 of 1 related geneB3GLCT Colorectal cancer Linked via 1 of 1 related geneB3GLCT

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Atrial fibrillation	1	["B3GLCT"]
Atrophic macular degeneration	1	["B3GLCT"]
Bipolar disorder	1	["B3GLCT"]
Cardiovascular disease	1	["B3GLCT"]
Colorectal cancer	1	["B3GLCT"]