Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs Other IDs Associated diseases
Entrez ID	113026
Gene name	Phospholipase C delta 3
Gene symbol	PLCD3
Synonyms (NCBI Gene)	PLC-delta-3
Chromosome	17
Chromosome location	17q21.31
Summary	This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a vari

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miRTarBase ID	miRNA	Experiments	Reference
MIRT018736	hsa-miR-335-5p	Microarray	18185580
MIRT044610	hsa-miR-320a	CLASH	23622248
MIRT755438	hsa-miR-34a-5p	Luciferase reporter assayWestern blottingqRT-PCR	37079115
MIRT1239800	hsa-miR-1	CLIP-seq
MIRT1239801	hsa-miR-10a	CLIP-seq
MIRT1239802	hsa-miR-10b	CLIP-seq
MIRT1239803	hsa-miR-1203	CLIP-seq
MIRT1239804	hsa-miR-1228	CLIP-seq
MIRT1239805	hsa-miR-1248	CLIP-seq
MIRT1239806	hsa-miR-1253	CLIP-seq
MIRT1239807	hsa-miR-125a-3p	CLIP-seq
MIRT1239808	hsa-miR-1275	CLIP-seq
MIRT1239809	hsa-miR-1289	CLIP-seq
MIRT1239810	hsa-miR-1321	CLIP-seq
MIRT1239811	hsa-miR-143	CLIP-seq
MIRT1239812	hsa-miR-1972	CLIP-seq
MIRT1239813	hsa-miR-206	CLIP-seq
MIRT1239814	hsa-miR-2114	CLIP-seq
MIRT1239815	hsa-miR-24	CLIP-seq
MIRT1239816	hsa-miR-2682	CLIP-seq
MIRT1239817	hsa-miR-28-5p	CLIP-seq
MIRT1239818	hsa-miR-3065-3p	CLIP-seq
MIRT1239819	hsa-miR-3135b	CLIP-seq
MIRT1239820	hsa-miR-3139	CLIP-seq
MIRT1239821	hsa-miR-3154	CLIP-seq
MIRT1239822	hsa-miR-3173-3p	CLIP-seq
MIRT1239823	hsa-miR-3179	CLIP-seq
MIRT1239824	hsa-miR-3202	CLIP-seq
MIRT1239825	hsa-miR-326	CLIP-seq
MIRT1239826	hsa-miR-330-5p	CLIP-seq
MIRT1239827	hsa-miR-339-5p	CLIP-seq
MIRT1239828	hsa-miR-342-3p	CLIP-seq
MIRT1239829	hsa-miR-34a	CLIP-seq
MIRT1239830	hsa-miR-34c-5p	CLIP-seq
MIRT1239831	hsa-miR-3613-3p	CLIP-seq
MIRT1239832	hsa-miR-3614-5p	CLIP-seq
MIRT1239833	hsa-miR-3616-3p	CLIP-seq
MIRT1239834	hsa-miR-3673	CLIP-seq
MIRT1239835	hsa-miR-371-5p	CLIP-seq
MIRT1239836	hsa-miR-371b-5p	CLIP-seq
MIRT1239837	hsa-miR-4271	CLIP-seq
MIRT1239838	hsa-miR-4284	CLIP-seq
MIRT1239839	hsa-miR-4419a	CLIP-seq
MIRT1239840	hsa-miR-4421	CLIP-seq
MIRT1239841	hsa-miR-4433	CLIP-seq
MIRT1239842	hsa-miR-4464	CLIP-seq
MIRT1239843	hsa-miR-4471	CLIP-seq
MIRT1239844	hsa-miR-4476	CLIP-seq
MIRT1239845	hsa-miR-4487	CLIP-seq
MIRT1239846	hsa-miR-4493	CLIP-seq
MIRT1239847	hsa-miR-449a	CLIP-seq
MIRT1239848	hsa-miR-449b	CLIP-seq
MIRT1239849	hsa-miR-449c	CLIP-seq
MIRT1239850	hsa-miR-4505	CLIP-seq
MIRT1239851	hsa-miR-4510	CLIP-seq
MIRT1239852	hsa-miR-4514	CLIP-seq
MIRT1239853	hsa-miR-4525	CLIP-seq
MIRT1239854	hsa-miR-4533	CLIP-seq
MIRT1239855	hsa-miR-4645-5p	CLIP-seq
MIRT1239856	hsa-miR-4662a-5p	CLIP-seq
MIRT1239857	hsa-miR-4665-5p	CLIP-seq
MIRT1239858	hsa-miR-4667-5p	CLIP-seq
MIRT1239859	hsa-miR-4673	CLIP-seq
MIRT1239860	hsa-miR-4676-5p	CLIP-seq
MIRT1239861	hsa-miR-4687-5p	CLIP-seq
MIRT1239862	hsa-miR-4692	CLIP-seq
MIRT1239863	hsa-miR-4700-5p	CLIP-seq
MIRT1239864	hsa-miR-4721	CLIP-seq
MIRT1239865	hsa-miR-4722-5p	CLIP-seq
MIRT1239866	hsa-miR-4723-5p	CLIP-seq
MIRT1239867	hsa-miR-4725-3p	CLIP-seq
MIRT1239868	hsa-miR-4725-5p	CLIP-seq
MIRT1239869	hsa-miR-4726-3p	CLIP-seq
MIRT1239870	hsa-miR-4731-5p	CLIP-seq
MIRT1239871	hsa-miR-4739	CLIP-seq
MIRT1239872	hsa-miR-4747-5p	CLIP-seq
MIRT1239873	hsa-miR-4748	CLIP-seq
MIRT1239874	hsa-miR-4755-3p	CLIP-seq
MIRT1239875	hsa-miR-4756-5p	CLIP-seq
MIRT1239876	hsa-miR-4786-5p	CLIP-seq
MIRT1239877	hsa-miR-486-3p	CLIP-seq
MIRT1239878	hsa-miR-504	CLIP-seq
MIRT1239879	hsa-miR-510	CLIP-seq
MIRT1239880	hsa-miR-548aa	CLIP-seq
MIRT1239881	hsa-miR-548ac	CLIP-seq
MIRT1239882	hsa-miR-548ae	CLIP-seq
MIRT1239883	hsa-miR-548aj	CLIP-seq
MIRT1239884	hsa-miR-548am	CLIP-seq
MIRT1239885	hsa-miR-548d-3p	CLIP-seq
MIRT1239886	hsa-miR-548x	CLIP-seq
MIRT1239887	hsa-miR-548z	CLIP-seq
MIRT1239888	hsa-miR-550a	CLIP-seq
MIRT1239889	hsa-miR-575	CLIP-seq
MIRT1239890	hsa-miR-580	CLIP-seq
MIRT1239891	hsa-miR-613	CLIP-seq
MIRT1239892	hsa-miR-625	CLIP-seq
MIRT1239893	hsa-miR-637	CLIP-seq
MIRT1239894	hsa-miR-661	CLIP-seq
MIRT1239895	hsa-miR-708	CLIP-seq
MIRT1239896	hsa-miR-765	CLIP-seq
MIRT1239897	hsa-miR-769-5p	CLIP-seq
MIRT1239841	hsa-miR-4433	CLIP-seq
MIRT1239804	hsa-miR-1228	CLIP-seq
MIRT1239805	hsa-miR-1248	CLIP-seq
MIRT1239807	hsa-miR-125a-3p	CLIP-seq
MIRT2070520	hsa-miR-1266	CLIP-seq
MIRT2070521	hsa-miR-1285	CLIP-seq
MIRT2070522	hsa-miR-1294	CLIP-seq
MIRT1239810	hsa-miR-1321	CLIP-seq
MIRT1239811	hsa-miR-143	CLIP-seq
MIRT2070523	hsa-miR-1976	CLIP-seq
MIRT2070524	hsa-miR-224	CLIP-seq
MIRT1239815	hsa-miR-24	CLIP-seq
MIRT2070525	hsa-miR-25	CLIP-seq
MIRT1239816	hsa-miR-2682	CLIP-seq
MIRT1239817	hsa-miR-28-5p	CLIP-seq
MIRT2070526	hsa-miR-296-5p	CLIP-seq
MIRT1239818	hsa-miR-3065-3p	CLIP-seq
MIRT1239820	hsa-miR-3139	CLIP-seq
MIRT2070527	hsa-miR-3162-5p	CLIP-seq
MIRT2070528	hsa-miR-3184	CLIP-seq
MIRT2070529	hsa-miR-3187-5p	CLIP-seq
MIRT2070530	hsa-miR-3192	CLIP-seq
MIRT2070531	hsa-miR-32	CLIP-seq
MIRT2070532	hsa-miR-320b	CLIP-seq
MIRT2070533	hsa-miR-320c	CLIP-seq
MIRT2070534	hsa-miR-320d	CLIP-seq
MIRT2070535	hsa-miR-330-3p	CLIP-seq
MIRT1239828	hsa-miR-342-3p	CLIP-seq
MIRT1239829	hsa-miR-34a	CLIP-seq
MIRT1239830	hsa-miR-34c-5p	CLIP-seq
MIRT1239832	hsa-miR-3614-5p	CLIP-seq
MIRT2070536	hsa-miR-363	CLIP-seq
MIRT2070537	hsa-miR-367	CLIP-seq
MIRT2070538	hsa-miR-3925-3p	CLIP-seq
MIRT2070539	hsa-miR-423-5p	CLIP-seq
MIRT2070540	hsa-miR-4258	CLIP-seq
MIRT2070541	hsa-miR-4268	CLIP-seq
MIRT1239838	hsa-miR-4284	CLIP-seq
MIRT2070542	hsa-miR-4325	CLIP-seq
MIRT2070543	hsa-miR-4429	CLIP-seq
MIRT1239841	hsa-miR-4433	CLIP-seq
MIRT2070544	hsa-miR-4438	CLIP-seq
MIRT2070545	hsa-miR-4486	CLIP-seq
MIRT1239845	hsa-miR-4487	CLIP-seq
MIRT1239847	hsa-miR-449a	CLIP-seq
MIRT1239848	hsa-miR-449b	CLIP-seq
MIRT1239849	hsa-miR-449c	CLIP-seq
MIRT1239852	hsa-miR-4514	CLIP-seq
MIRT2070546	hsa-miR-4518	CLIP-seq
MIRT2070547	hsa-miR-4529-5p	CLIP-seq
MIRT1239855	hsa-miR-4645-5p	CLIP-seq
MIRT2070548	hsa-miR-4649-5p	CLIP-seq
MIRT2070549	hsa-miR-4651	CLIP-seq
MIRT1239859	hsa-miR-4673	CLIP-seq
MIRT2070550	hsa-miR-4685-5p	CLIP-seq
MIRT1239861	hsa-miR-4687-5p	CLIP-seq
MIRT1239862	hsa-miR-4692	CLIP-seq
MIRT1239869	hsa-miR-4726-3p	CLIP-seq
MIRT1239870	hsa-miR-4731-5p	CLIP-seq
MIRT1239871	hsa-miR-4739	CLIP-seq
MIRT1239872	hsa-miR-4747-5p	CLIP-seq
MIRT1239874	hsa-miR-4755-3p	CLIP-seq
MIRT1239875	hsa-miR-4756-5p	CLIP-seq
MIRT1239876	hsa-miR-4786-5p	CLIP-seq
MIRT2070551	hsa-miR-508-5p	CLIP-seq
MIRT2070552	hsa-miR-515-5p	CLIP-seq
MIRT2070553	hsa-miR-541	CLIP-seq
MIRT2070554	hsa-miR-608	CLIP-seq
MIRT2070555	hsa-miR-612	CLIP-seq
MIRT2070556	hsa-miR-654-5p	CLIP-seq
MIRT1239894	hsa-miR-661	CLIP-seq
MIRT1239895	hsa-miR-708	CLIP-seq
MIRT2070557	hsa-miR-766	CLIP-seq
MIRT2070558	hsa-miR-885-3p	CLIP-seq
MIRT2070559	hsa-miR-92a	CLIP-seq
MIRT2070560	hsa-miR-92b	CLIP-seq
MIRT2070561	hsa-miR-942	CLIP-seq
MIRT1239804	hsa-miR-1228	CLIP-seq
MIRT2070521	hsa-miR-1285	CLIP-seq
MIRT1239810	hsa-miR-1321	CLIP-seq
MIRT1239811	hsa-miR-143	CLIP-seq
MIRT1239814	hsa-miR-2114	CLIP-seq
MIRT1239815	hsa-miR-24	CLIP-seq
MIRT2070525	hsa-miR-25	CLIP-seq
MIRT1239816	hsa-miR-2682	CLIP-seq
MIRT1239817	hsa-miR-28-5p	CLIP-seq
MIRT1239820	hsa-miR-3139	CLIP-seq
MIRT2070527	hsa-miR-3162-5p	CLIP-seq
MIRT2070529	hsa-miR-3187-5p	CLIP-seq
MIRT2070530	hsa-miR-3192	CLIP-seq
MIRT2070531	hsa-miR-32	CLIP-seq
MIRT2070532	hsa-miR-320b	CLIP-seq
MIRT2070533	hsa-miR-320c	CLIP-seq
MIRT2070534	hsa-miR-320d	CLIP-seq
MIRT2070535	hsa-miR-330-3p	CLIP-seq
MIRT1239828	hsa-miR-342-3p	CLIP-seq
MIRT1239829	hsa-miR-34a	CLIP-seq
MIRT1239830	hsa-miR-34c-5p	CLIP-seq
MIRT1239832	hsa-miR-3614-5p	CLIP-seq
MIRT2070536	hsa-miR-363	CLIP-seq
MIRT2070537	hsa-miR-367	CLIP-seq
MIRT2070540	hsa-miR-4258	CLIP-seq
MIRT1239838	hsa-miR-4284	CLIP-seq
MIRT2070542	hsa-miR-4325	CLIP-seq
MIRT2070543	hsa-miR-4429	CLIP-seq
MIRT1239841	hsa-miR-4433	CLIP-seq
MIRT2070545	hsa-miR-4486	CLIP-seq
MIRT1239845	hsa-miR-4487	CLIP-seq
MIRT1239847	hsa-miR-449a	CLIP-seq
MIRT1239848	hsa-miR-449b	CLIP-seq
MIRT1239849	hsa-miR-449c	CLIP-seq
MIRT1239852	hsa-miR-4514	CLIP-seq
MIRT1239855	hsa-miR-4645-5p	CLIP-seq
MIRT2070548	hsa-miR-4649-5p	CLIP-seq
MIRT1239859	hsa-miR-4673	CLIP-seq
MIRT1239862	hsa-miR-4692	CLIP-seq
MIRT1239871	hsa-miR-4739	CLIP-seq
MIRT1239874	hsa-miR-4755-3p	CLIP-seq
MIRT1239875	hsa-miR-4756-5p	CLIP-seq
MIRT1239876	hsa-miR-4786-5p	CLIP-seq
MIRT2070551	hsa-miR-508-5p	CLIP-seq
MIRT1239879	hsa-miR-510	CLIP-seq
MIRT2070555	hsa-miR-612	CLIP-seq
MIRT1239894	hsa-miR-661	CLIP-seq
MIRT1239895	hsa-miR-708	CLIP-seq
MIRT2070557	hsa-miR-766	CLIP-seq
MIRT2070559	hsa-miR-92a	CLIP-seq
MIRT2070560	hsa-miR-92b	CLIP-seq
MIRT2070521	hsa-miR-1285	CLIP-seq
MIRT1239810	hsa-miR-1321	CLIP-seq
MIRT2070525	hsa-miR-25	CLIP-seq
MIRT2070527	hsa-miR-3162-5p	CLIP-seq
MIRT2070529	hsa-miR-3187-5p	CLIP-seq
MIRT2070531	hsa-miR-32	CLIP-seq
MIRT2070536	hsa-miR-363	CLIP-seq
MIRT2070537	hsa-miR-367	CLIP-seq
MIRT2070542	hsa-miR-4325	CLIP-seq
MIRT2070545	hsa-miR-4486	CLIP-seq
MIRT2070548	hsa-miR-4649-5p	CLIP-seq
MIRT1239871	hsa-miR-4739	CLIP-seq
MIRT1239875	hsa-miR-4756-5p	CLIP-seq
MIRT1239876	hsa-miR-4786-5p	CLIP-seq
MIRT2070551	hsa-miR-508-5p	CLIP-seq
MIRT2070555	hsa-miR-612	CLIP-seq
MIRT1239894	hsa-miR-661	CLIP-seq
MIRT2070557	hsa-miR-766	CLIP-seq
MIRT2070559	hsa-miR-92a	CLIP-seq
MIRT2070560	hsa-miR-92b	CLIP-seq
MIRT2070521	hsa-miR-1285	CLIP-seq
MIRT1239810	hsa-miR-1321	CLIP-seq
MIRT2070527	hsa-miR-3162-5p	CLIP-seq
MIRT2070529	hsa-miR-3187-5p	CLIP-seq
MIRT1239871	hsa-miR-4739	CLIP-seq
MIRT1239875	hsa-miR-4756-5p	CLIP-seq
MIRT1239876	hsa-miR-4786-5p	CLIP-seq
MIRT2070555	hsa-miR-612	CLIP-seq
MIRT1239894	hsa-miR-661	CLIP-seq
MIRT1239800	hsa-miR-1	CLIP-seq
MIRT1239801	hsa-miR-10a	CLIP-seq
MIRT1239802	hsa-miR-10b	CLIP-seq
MIRT1239804	hsa-miR-1228	CLIP-seq
MIRT1239805	hsa-miR-1248	CLIP-seq
MIRT1239806	hsa-miR-1253	CLIP-seq
MIRT2070521	hsa-miR-1285	CLIP-seq
MIRT1239809	hsa-miR-1289	CLIP-seq
MIRT1239810	hsa-miR-1321	CLIP-seq
MIRT1239811	hsa-miR-143	CLIP-seq
MIRT2595166	hsa-miR-1915	CLIP-seq
MIRT1239813	hsa-miR-206	CLIP-seq
MIRT2595167	hsa-miR-2355-5p	CLIP-seq
MIRT2070525	hsa-miR-25	CLIP-seq
MIRT1239817	hsa-miR-28-5p	CLIP-seq
MIRT1239819	hsa-miR-3135b	CLIP-seq
MIRT1239820	hsa-miR-3139	CLIP-seq
MIRT1239821	hsa-miR-3154	CLIP-seq
MIRT2595168	hsa-miR-3158-3p	CLIP-seq
MIRT2070527	hsa-miR-3162-5p	CLIP-seq
MIRT1239823	hsa-miR-3179	CLIP-seq
MIRT2070529	hsa-miR-3187-5p	CLIP-seq
MIRT2070530	hsa-miR-3192	CLIP-seq
MIRT2070531	hsa-miR-32	CLIP-seq
MIRT1239824	hsa-miR-3202	CLIP-seq
MIRT1239827	hsa-miR-339-5p	CLIP-seq
MIRT1239831	hsa-miR-3613-3p	CLIP-seq
MIRT1239832	hsa-miR-3614-5p	CLIP-seq
MIRT2070536	hsa-miR-363	CLIP-seq
MIRT2070537	hsa-miR-367	CLIP-seq
MIRT2595169	hsa-miR-3670	CLIP-seq
MIRT1239834	hsa-miR-3673	CLIP-seq
MIRT2595170	hsa-miR-3679-3p	CLIP-seq
MIRT1239835	hsa-miR-371-5p	CLIP-seq
MIRT1239836	hsa-miR-371b-5p	CLIP-seq
MIRT2595171	hsa-miR-4287	CLIP-seq
MIRT2595172	hsa-miR-4300	CLIP-seq
MIRT2070542	hsa-miR-4325	CLIP-seq
MIRT1239839	hsa-miR-4419a	CLIP-seq
MIRT1239840	hsa-miR-4421	CLIP-seq
MIRT1239841	hsa-miR-4433	CLIP-seq
MIRT1239844	hsa-miR-4476	CLIP-seq
MIRT2070545	hsa-miR-4486	CLIP-seq
MIRT1239845	hsa-miR-4487	CLIP-seq
MIRT1239851	hsa-miR-4510	CLIP-seq
MIRT2070548	hsa-miR-4649-5p	CLIP-seq
MIRT2595173	hsa-miR-4685-3p	CLIP-seq
MIRT2070550	hsa-miR-4685-5p	CLIP-seq
MIRT1239865	hsa-miR-4722-5p	CLIP-seq
MIRT1239868	hsa-miR-4725-5p	CLIP-seq
MIRT1239870	hsa-miR-4731-5p	CLIP-seq
MIRT1239871	hsa-miR-4739	CLIP-seq
MIRT1239872	hsa-miR-4747-5p	CLIP-seq
MIRT1239875	hsa-miR-4756-5p	CLIP-seq
MIRT1239876	hsa-miR-4786-5p	CLIP-seq
MIRT1239877	hsa-miR-486-3p	CLIP-seq
MIRT1239878	hsa-miR-504	CLIP-seq
MIRT2070551	hsa-miR-508-5p	CLIP-seq
MIRT1239880	hsa-miR-548aa	CLIP-seq
MIRT1239881	hsa-miR-548ac	CLIP-seq
MIRT1239882	hsa-miR-548ae	CLIP-seq
MIRT1239883	hsa-miR-548aj	CLIP-seq
MIRT1239884	hsa-miR-548am	CLIP-seq
MIRT1239885	hsa-miR-548d-3p	CLIP-seq
MIRT1239886	hsa-miR-548x	CLIP-seq
MIRT1239887	hsa-miR-548z	CLIP-seq
MIRT1239890	hsa-miR-580	CLIP-seq
MIRT2070555	hsa-miR-612	CLIP-seq
MIRT1239891	hsa-miR-613	CLIP-seq
MIRT1239894	hsa-miR-661	CLIP-seq
MIRT1239895	hsa-miR-708	CLIP-seq
MIRT1239896	hsa-miR-765	CLIP-seq
MIRT2070557	hsa-miR-766	CLIP-seq
MIRT2595174	hsa-miR-920	CLIP-seq
MIRT2070559	hsa-miR-92a	CLIP-seq
MIRT2070560	hsa-miR-92b	CLIP-seq
MIRT2595175	hsa-miR-939	CLIP-seq
MIRT1239800	hsa-miR-1	CLIP-seq
MIRT1239801	hsa-miR-10a	CLIP-seq
MIRT1239802	hsa-miR-10b	CLIP-seq
MIRT1239804	hsa-miR-1228	CLIP-seq
MIRT2070521	hsa-miR-1285	CLIP-seq
MIRT1239809	hsa-miR-1289	CLIP-seq
MIRT1239810	hsa-miR-1321	CLIP-seq
MIRT1239813	hsa-miR-206	CLIP-seq
MIRT2070525	hsa-miR-25	CLIP-seq
MIRT1239819	hsa-miR-3135b	CLIP-seq
MIRT2070527	hsa-miR-3162-5p	CLIP-seq
MIRT2070529	hsa-miR-3187-5p	CLIP-seq
MIRT2070531	hsa-miR-32	CLIP-seq
MIRT1239827	hsa-miR-339-5p	CLIP-seq
MIRT1239831	hsa-miR-3613-3p	CLIP-seq
MIRT1239832	hsa-miR-3614-5p	CLIP-seq
MIRT2070536	hsa-miR-363	CLIP-seq
MIRT2070537	hsa-miR-367	CLIP-seq
MIRT1239834	hsa-miR-3673	CLIP-seq
MIRT1239835	hsa-miR-371-5p	CLIP-seq
MIRT1239836	hsa-miR-371b-5p	CLIP-seq
MIRT2070542	hsa-miR-4325	CLIP-seq
MIRT1239839	hsa-miR-4419a	CLIP-seq
MIRT1239840	hsa-miR-4421	CLIP-seq
MIRT1239841	hsa-miR-4433	CLIP-seq
MIRT1239844	hsa-miR-4476	CLIP-seq
MIRT2070545	hsa-miR-4486	CLIP-seq
MIRT1239845	hsa-miR-4487	CLIP-seq
MIRT1239851	hsa-miR-4510	CLIP-seq
MIRT2070548	hsa-miR-4649-5p	CLIP-seq
MIRT1239865	hsa-miR-4722-5p	CLIP-seq
MIRT1239868	hsa-miR-4725-5p	CLIP-seq
MIRT1239870	hsa-miR-4731-5p	CLIP-seq
MIRT1239871	hsa-miR-4739	CLIP-seq
MIRT1239875	hsa-miR-4756-5p	CLIP-seq
MIRT1239876	hsa-miR-4786-5p	CLIP-seq
MIRT1239877	hsa-miR-486-3p	CLIP-seq
MIRT1239878	hsa-miR-504	CLIP-seq
MIRT2070551	hsa-miR-508-5p	CLIP-seq
MIRT1239880	hsa-miR-548aa	CLIP-seq
MIRT1239881	hsa-miR-548ac	CLIP-seq
MIRT1239882	hsa-miR-548ae	CLIP-seq
MIRT1239883	hsa-miR-548aj	CLIP-seq
MIRT1239884	hsa-miR-548am	CLIP-seq
MIRT1239885	hsa-miR-548d-3p	CLIP-seq
MIRT1239886	hsa-miR-548x	CLIP-seq
MIRT1239887	hsa-miR-548z	CLIP-seq
MIRT2070555	hsa-miR-612	CLIP-seq
MIRT1239891	hsa-miR-613	CLIP-seq
MIRT1239894	hsa-miR-661	CLIP-seq
MIRT1239896	hsa-miR-765	CLIP-seq
MIRT2070557	hsa-miR-766	CLIP-seq
MIRT2070559	hsa-miR-92a	CLIP-seq
MIRT2070560	hsa-miR-92b	CLIP-seq

Show/Hide all (17)

GO ID	Ontology	Definition	Evidence
GO:0001525	Process	Angiogenesis	IEA
GO:0004435	Function	Phosphatidylinositol-4,5-bisphosphate phospholipase C activity	IBA
GO:0004435	Function	Phosphatidylinositol-4,5-bisphosphate phospholipase C activity	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0008081	Function	Phosphoric diester hydrolase activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0016042	Process	Lipid catabolic process	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0032154	Component	Cleavage furrow	IEA
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0042127	Process	Regulation of cell population proliferation	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0060716	Process	Labyrinthine layer blood vessel development	IEA

MIM	HGNC	e!Ensembl
608795	9061	ENSG00000161714

Q8N3E9

Protein name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-3) (Phospholipase C-delta-3) (PLC-delta-3)

Protein function

Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) fr

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF14788	EF-hand_10	201 → 250	EF hand	Domain
PF00388	PI-PLC-X	339 → 483	Phosphatidylinositol-specific phospholipase C, X domain	Family
PF00387	PI-PLC-Y	528 → 642	Phosphatidylinositol-specific phospholipase C, Y domain	Family
PF00168	C2	660 → 769	C2 domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Present in corneal epithelial cells (at protein level). {ECO:0000269|PubMed:15505048}.

Sequence

MLCGRWRRCRRPPEEPPVAAQVAAQVAAPVALPSPPTPSDGGTKRPGLRALKKMGLTEDE
DVRAMLRGSRLRKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAPSQHIFFVQHIEAVREG
HQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLTKLRARLDAMSQR
ERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECDHSNNDRLEG
AEIEEFLRRLLKRPELEEIFHQYSGEDRVLSAPELLEFLEDQGEEGATLARAQQLIQTYE
LNETAKQHELMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLAHYFISSSHNTYLTDSQ
IGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFT
LSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNPEELPSPEQLKGRVLVK
GKKLPAARSEDGRALSDREEEEEDDEEEEEEVEAAAQRRLAKQISPELSALAVYCHATRL
RTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQ
EMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPACLRQPDSTFDPEYPGPPRT
TLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPADCARQETDYVLNNGFNPRWGQTL
QFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLSSLKQGYRHIHLLSKDGASLSPATL
FIQIRIQRS

Sequence length

789

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CORONARY ARTERY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MIGRAINE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (9)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	31808619		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	33674820	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	31808619	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary heart disease	Coronary Heart Disease	GWASDB_DG	21347282		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	19430483	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	33674820	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	29115528		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	29115528	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	32489258, 33674820	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

PLCD3 (phospholipase C delta 3)