PLAC4 (placenta enriched 4)

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Gene miRNA Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 191585
• Gene name: Placenta enriched 4
• Gene symbol: PLAC4
• Synonyms (NCBI Gene): C21orf115, PRED78
• Chromosome: 21
• Chromosome location: 21q22.2

miRNA Show/Hide all (253)

miRTarBase ID	miRNA	Experiments	Reference
MIRT1238880	hsa-miR-1229	CLIP-seq
MIRT1238881	hsa-miR-1236	CLIP-seq
MIRT1238882	hsa-miR-1293	CLIP-seq
MIRT1238883	hsa-miR-1324	CLIP-seq
MIRT1238884	hsa-miR-147	CLIP-seq
MIRT1238885	hsa-miR-154	CLIP-seq
MIRT1238886	hsa-miR-1825	CLIP-seq
MIRT1238887	hsa-miR-1827	CLIP-seq
MIRT1238888	hsa-miR-2114	CLIP-seq
MIRT1238889	hsa-miR-214	CLIP-seq
MIRT1238890	hsa-miR-219-2-3p	CLIP-seq
MIRT1238891	hsa-miR-300	CLIP-seq
MIRT1238892	hsa-miR-3130-3p	CLIP-seq
MIRT1238893	hsa-miR-3135	CLIP-seq
MIRT1238894	hsa-miR-3144-3p	CLIP-seq
MIRT1238895	hsa-miR-3150b-3p	CLIP-seq
MIRT1238896	hsa-miR-3166	CLIP-seq
MIRT1238897	hsa-miR-3183	CLIP-seq
MIRT1238898	hsa-miR-3184	CLIP-seq
MIRT1238899	hsa-miR-342-3p	CLIP-seq
MIRT1238900	hsa-miR-34b	CLIP-seq
MIRT1238901	hsa-miR-3614-5p	CLIP-seq
MIRT1238902	hsa-miR-3617	CLIP-seq
MIRT1238903	hsa-miR-3619-5p	CLIP-seq
MIRT1238904	hsa-miR-3664-3p	CLIP-seq
MIRT1238905	hsa-miR-3670	CLIP-seq
MIRT1238906	hsa-miR-3689d	CLIP-seq
MIRT1238907	hsa-miR-381	CLIP-seq
MIRT1238908	hsa-miR-384	CLIP-seq
MIRT1238909	hsa-miR-3911	CLIP-seq
MIRT1238910	hsa-miR-3921	CLIP-seq
MIRT1238911	hsa-miR-3922-5p	CLIP-seq
MIRT1238912	hsa-miR-3929	CLIP-seq
MIRT1238913	hsa-miR-3974	CLIP-seq
MIRT1238914	hsa-miR-423-5p	CLIP-seq
MIRT1238915	hsa-miR-4266	CLIP-seq
MIRT1238916	hsa-miR-4326	CLIP-seq
MIRT1238917	hsa-miR-4419b	CLIP-seq
MIRT1238918	hsa-miR-4424	CLIP-seq
MIRT1238919	hsa-miR-4433	CLIP-seq
MIRT1238920	hsa-miR-4459	CLIP-seq
MIRT1238921	hsa-miR-4463	CLIP-seq
MIRT1238922	hsa-miR-4474-3p	CLIP-seq
MIRT1238923	hsa-miR-4478	CLIP-seq
MIRT1238924	hsa-miR-4483	CLIP-seq
MIRT1238925	hsa-miR-4514	CLIP-seq
MIRT1238926	hsa-miR-451b	CLIP-seq
MIRT1238927	hsa-miR-4649-3p	CLIP-seq
MIRT1238928	hsa-miR-4651	CLIP-seq
MIRT1238929	hsa-miR-4653-5p	CLIP-seq
MIRT1238930	hsa-miR-4666-3p	CLIP-seq
MIRT1238931	hsa-miR-4676-5p	CLIP-seq
MIRT1238932	hsa-miR-4689	CLIP-seq
MIRT1238933	hsa-miR-4690-5p	CLIP-seq
MIRT1238934	hsa-miR-4692	CLIP-seq
MIRT1238935	hsa-miR-4695-5p	CLIP-seq
MIRT1238936	hsa-miR-4710	CLIP-seq
MIRT1238937	hsa-miR-4722-5p	CLIP-seq
MIRT1238938	hsa-miR-4723-3p	CLIP-seq
MIRT1238939	hsa-miR-4742-3p	CLIP-seq
MIRT1238940	hsa-miR-4768-3p	CLIP-seq
MIRT1238941	hsa-miR-4779	CLIP-seq
MIRT1238942	hsa-miR-4784	CLIP-seq
MIRT1238943	hsa-miR-4787-5p	CLIP-seq
MIRT1238944	hsa-miR-4792	CLIP-seq
MIRT1238945	hsa-miR-485-5p	CLIP-seq
MIRT1238946	hsa-miR-486-5p	CLIP-seq
MIRT1238947	hsa-miR-510	CLIP-seq
MIRT1238948	hsa-miR-512-5p	CLIP-seq
MIRT1238949	hsa-miR-515-5p	CLIP-seq
MIRT1238950	hsa-miR-518d-5p	CLIP-seq
MIRT1238951	hsa-miR-519b-5p	CLIP-seq
MIRT1238952	hsa-miR-519c-5p	CLIP-seq
MIRT1238953	hsa-miR-520c-5p	CLIP-seq
MIRT1238954	hsa-miR-520f	CLIP-seq
MIRT1238955	hsa-miR-526a	CLIP-seq
MIRT1238956	hsa-miR-548c-3p	CLIP-seq
MIRT1238957	hsa-miR-575	CLIP-seq
MIRT1238958	hsa-miR-582-3p	CLIP-seq
MIRT1238959	hsa-miR-595	CLIP-seq
MIRT1238960	hsa-miR-608	CLIP-seq
MIRT1238961	hsa-miR-636	CLIP-seq
MIRT1238962	hsa-miR-641	CLIP-seq
MIRT1238963	hsa-miR-644	CLIP-seq
MIRT1238964	hsa-miR-7	CLIP-seq
MIRT1238965	hsa-miR-761	CLIP-seq
MIRT1238966	hsa-miR-765	CLIP-seq
MIRT1238967	hsa-miR-875-5p	CLIP-seq
MIRT1238968	hsa-miR-885-3p	CLIP-seq
MIRT1238969	hsa-miR-940	CLIP-seq
MIRT1238882	hsa-miR-1293	CLIP-seq
MIRT2070278	hsa-miR-145	CLIP-seq
MIRT1238887	hsa-miR-1827	CLIP-seq
MIRT2070279	hsa-miR-1914	CLIP-seq
MIRT1238888	hsa-miR-2114	CLIP-seq
MIRT2070280	hsa-miR-302a	CLIP-seq
MIRT2070281	hsa-miR-302b	CLIP-seq
MIRT2070282	hsa-miR-302c	CLIP-seq
MIRT2070283	hsa-miR-302d	CLIP-seq
MIRT2070284	hsa-miR-302e	CLIP-seq
MIRT1238892	hsa-miR-3130-3p	CLIP-seq
MIRT2070285	hsa-miR-3202	CLIP-seq
MIRT2070286	hsa-miR-323-5p	CLIP-seq
MIRT1238901	hsa-miR-3614-5p	CLIP-seq
MIRT1238904	hsa-miR-3664-3p	CLIP-seq
MIRT1238905	hsa-miR-3670	CLIP-seq
MIRT2070287	hsa-miR-372	CLIP-seq
MIRT2070288	hsa-miR-373	CLIP-seq
MIRT2070289	hsa-miR-3918	CLIP-seq
MIRT1238911	hsa-miR-3922-5p	CLIP-seq
MIRT1238912	hsa-miR-3929	CLIP-seq
MIRT2070290	hsa-miR-4303	CLIP-seq
MIRT2070291	hsa-miR-4307	CLIP-seq
MIRT1238917	hsa-miR-4419b	CLIP-seq
MIRT1238919	hsa-miR-4433	CLIP-seq
MIRT2070292	hsa-miR-4453	CLIP-seq
MIRT2070293	hsa-miR-4457	CLIP-seq
MIRT1238920	hsa-miR-4459	CLIP-seq
MIRT1238921	hsa-miR-4463	CLIP-seq
MIRT1238923	hsa-miR-4478	CLIP-seq
MIRT1238924	hsa-miR-4483	CLIP-seq
MIRT2070294	hsa-miR-4538	CLIP-seq
MIRT1238927	hsa-miR-4649-3p	CLIP-seq
MIRT2070295	hsa-miR-4659a-3p	CLIP-seq
MIRT2070296	hsa-miR-4659b-3p	CLIP-seq
MIRT1238935	hsa-miR-4695-5p	CLIP-seq
MIRT1238937	hsa-miR-4722-5p	CLIP-seq
MIRT2070297	hsa-miR-4761-5p	CLIP-seq
MIRT1238940	hsa-miR-4768-3p	CLIP-seq
MIRT1238945	hsa-miR-485-5p	CLIP-seq
MIRT1238947	hsa-miR-510	CLIP-seq
MIRT1238948	hsa-miR-512-5p	CLIP-seq
MIRT2070298	hsa-miR-520a-3p	CLIP-seq
MIRT2070299	hsa-miR-520b	CLIP-seq
MIRT2070300	hsa-miR-520c-3p	CLIP-seq
MIRT2070301	hsa-miR-520d-3p	CLIP-seq
MIRT2070302	hsa-miR-520e	CLIP-seq
MIRT2070303	hsa-miR-624	CLIP-seq
MIRT2070304	hsa-miR-876-3p	CLIP-seq
MIRT1238969	hsa-miR-940	CLIP-seq
MIRT2297535	hsa-miR-1207-5p	CLIP-seq
MIRT2297536	hsa-miR-1289	CLIP-seq
MIRT1238882	hsa-miR-1293	CLIP-seq
MIRT2297537	hsa-miR-129-5p	CLIP-seq
MIRT1238887	hsa-miR-1827	CLIP-seq
MIRT1238888	hsa-miR-2114	CLIP-seq
MIRT2297538	hsa-miR-3126-3p	CLIP-seq
MIRT1238898	hsa-miR-3184	CLIP-seq
MIRT2297539	hsa-miR-3198	CLIP-seq
MIRT2070285	hsa-miR-3202	CLIP-seq
MIRT1238901	hsa-miR-3614-5p	CLIP-seq
MIRT1238904	hsa-miR-3664-3p	CLIP-seq
MIRT1238905	hsa-miR-3670	CLIP-seq
MIRT2297540	hsa-miR-3689a-3p	CLIP-seq
MIRT2297541	hsa-miR-3689c	CLIP-seq
MIRT1238911	hsa-miR-3922-5p	CLIP-seq
MIRT1238912	hsa-miR-3929	CLIP-seq
MIRT1238914	hsa-miR-423-5p	CLIP-seq
MIRT1238915	hsa-miR-4266	CLIP-seq
MIRT2297542	hsa-miR-4294	CLIP-seq
MIRT2297543	hsa-miR-4309	CLIP-seq
MIRT2297544	hsa-miR-432	CLIP-seq
MIRT1238917	hsa-miR-4419b	CLIP-seq
MIRT1238919	hsa-miR-4433	CLIP-seq
MIRT1238920	hsa-miR-4459	CLIP-seq
MIRT1238923	hsa-miR-4478	CLIP-seq
MIRT1238924	hsa-miR-4483	CLIP-seq
MIRT2297545	hsa-miR-4639-5p	CLIP-seq
MIRT1238927	hsa-miR-4649-3p	CLIP-seq
MIRT1238928	hsa-miR-4651	CLIP-seq
MIRT1238935	hsa-miR-4695-5p	CLIP-seq
MIRT1238936	hsa-miR-4710	CLIP-seq
MIRT1238937	hsa-miR-4722-5p	CLIP-seq
MIRT2297546	hsa-miR-4728-5p	CLIP-seq
MIRT2297547	hsa-miR-4736	CLIP-seq
MIRT2297548	hsa-miR-4763-3p	CLIP-seq
MIRT1238940	hsa-miR-4768-3p	CLIP-seq
MIRT1238941	hsa-miR-4779	CLIP-seq
MIRT1238943	hsa-miR-4787-5p	CLIP-seq
MIRT1238944	hsa-miR-4792	CLIP-seq
MIRT1238945	hsa-miR-485-5p	CLIP-seq
MIRT1238947	hsa-miR-510	CLIP-seq
MIRT1238948	hsa-miR-512-5p	CLIP-seq
MIRT2297549	hsa-miR-513a-5p	CLIP-seq
MIRT1238960	hsa-miR-608	CLIP-seq
MIRT2297550	hsa-miR-634	CLIP-seq
MIRT1238966	hsa-miR-765	CLIP-seq
MIRT2297551	hsa-miR-890	CLIP-seq
MIRT1238969	hsa-miR-940	CLIP-seq
MIRT1238887	hsa-miR-1827	CLIP-seq
MIRT1238888	hsa-miR-2114	CLIP-seq
MIRT1238904	hsa-miR-3664-3p	CLIP-seq
MIRT1238912	hsa-miR-3929	CLIP-seq
MIRT1238917	hsa-miR-4419b	CLIP-seq
MIRT1238919	hsa-miR-4433	CLIP-seq
MIRT1238920	hsa-miR-4459	CLIP-seq
MIRT1238923	hsa-miR-4478	CLIP-seq
MIRT1238927	hsa-miR-4649-3p	CLIP-seq
MIRT1238935	hsa-miR-4695-5p	CLIP-seq
MIRT1238937	hsa-miR-4722-5p	CLIP-seq
MIRT1238940	hsa-miR-4768-3p	CLIP-seq
MIRT1238945	hsa-miR-485-5p	CLIP-seq
MIRT1238947	hsa-miR-510	CLIP-seq
MIRT1238948	hsa-miR-512-5p	CLIP-seq
MIRT1238969	hsa-miR-940	CLIP-seq
MIRT1238887	hsa-miR-1827	CLIP-seq
MIRT1238888	hsa-miR-2114	CLIP-seq
MIRT1238901	hsa-miR-3614-5p	CLIP-seq
MIRT1238904	hsa-miR-3664-3p	CLIP-seq
MIRT1238905	hsa-miR-3670	CLIP-seq
MIRT1238912	hsa-miR-3929	CLIP-seq
MIRT1238917	hsa-miR-4419b	CLIP-seq
MIRT1238919	hsa-miR-4433	CLIP-seq
MIRT1238920	hsa-miR-4459	CLIP-seq
MIRT1238923	hsa-miR-4478	CLIP-seq
MIRT1238926	hsa-miR-451b	CLIP-seq
MIRT1238927	hsa-miR-4649-3p	CLIP-seq
MIRT1238935	hsa-miR-4695-5p	CLIP-seq
MIRT1238937	hsa-miR-4722-5p	CLIP-seq
MIRT1238940	hsa-miR-4768-3p	CLIP-seq
MIRT1238945	hsa-miR-485-5p	CLIP-seq
MIRT1238947	hsa-miR-510	CLIP-seq
MIRT1238948	hsa-miR-512-5p	CLIP-seq
MIRT1238969	hsa-miR-940	CLIP-seq
MIRT2687981	hsa-miR-125a-5p	CLIP-seq
MIRT2687982	hsa-miR-125b	CLIP-seq
MIRT2687983	hsa-miR-146b-3p	CLIP-seq
MIRT1238886	hsa-miR-1825	CLIP-seq
MIRT1238887	hsa-miR-1827	CLIP-seq
MIRT2687984	hsa-miR-198	CLIP-seq
MIRT2687985	hsa-miR-199a-5p	CLIP-seq
MIRT2687986	hsa-miR-199b-5p	CLIP-seq
MIRT1238888	hsa-miR-2114	CLIP-seq
MIRT2687987	hsa-miR-22	CLIP-seq
MIRT2687988	hsa-miR-3173-5p	CLIP-seq
MIRT1238901	hsa-miR-3614-5p	CLIP-seq
MIRT1238904	hsa-miR-3664-3p	CLIP-seq
MIRT1238912	hsa-miR-3929	CLIP-seq
MIRT2687989	hsa-miR-4261	CLIP-seq
MIRT2687990	hsa-miR-4319	CLIP-seq
MIRT1238917	hsa-miR-4419b	CLIP-seq
MIRT1238919	hsa-miR-4433	CLIP-seq
MIRT1238920	hsa-miR-4459	CLIP-seq
MIRT1238923	hsa-miR-4478	CLIP-seq
MIRT1238927	hsa-miR-4649-3p	CLIP-seq
MIRT1238935	hsa-miR-4695-5p	CLIP-seq
MIRT1238937	hsa-miR-4722-5p	CLIP-seq
MIRT1238940	hsa-miR-4768-3p	CLIP-seq
MIRT1238945	hsa-miR-485-5p	CLIP-seq
MIRT1238947	hsa-miR-510	CLIP-seq
MIRT1238948	hsa-miR-512-5p	CLIP-seq
MIRT2687991	hsa-miR-874	CLIP-seq
MIRT1238969	hsa-miR-940	CLIP-seq

Other IDs

• MIM: 613770
• HGNC: 14616
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8WY50
• Protein name: Placenta-specific protein 4
• Tissue specificity: TISSUE SPECIFICITY: Expressed in placental syncytiotrophoblast and choriocarcinoma cells. {ECO:0000269|PubMed:8406465}.
• Sequence:

  MKELLRLKHCKHLLTTHVHSPWTPSLTLTPSLLTLDTLTHPRHRHSSPWTPHSAPWTPSL
  TLDTFTHPDTLTHPGHPHSPWIPSLLTLDTLTHPGYPHSSPWTLSLTLTPSILTLDSLTP
  HPGLPHSSPWTPSLLILDTLTQPGHPHSSP

• Sequence length: 150

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
PLAC4-related disorder	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Choriocarcinoma	Choriocarcinoma	BEFREE	8406465		★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down Syndrome	BEFREE	17206148, 19097032, 19892844, 22924494, 24214739, 28648597		★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down syndrome	Pubtator	22924494, 28648597	Associate	★☆☆☆☆ Found in Text Mining only
Heart Defects Congenital	Congenital heart defect	Pubtator	28648597	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for PLAC4.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PLAC4.