PHF23 (PHD finger protein 23)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 79142
• Gene name: PHD finger protein 23
• Gene symbol: PHF23
• Synonyms (NCBI Gene): hJUNE-1b
• Chromosome: 17
• Chromosome location: 17p13.1

miRNA Show/Hide all (229)

miRTarBase ID	miRNA	Experiments	Reference
MIRT043569	hsa-miR-331-3p	CLASH	23622248
MIRT042115	hsa-miR-484	CLASH	23622248
MIRT040585	hsa-miR-92b-3p	CLASH	23622248
MIRT038992	hsa-let-7e-3p	CLASH	23622248
MIRT1230994	hsa-miR-1207-5p	CLIP-seq
MIRT1230995	hsa-miR-1224-5p	CLIP-seq
MIRT1230996	hsa-miR-125a-5p	CLIP-seq
MIRT1230997	hsa-miR-125b	CLIP-seq
MIRT1230998	hsa-miR-1305	CLIP-seq
MIRT1230999	hsa-miR-1321	CLIP-seq
MIRT1231000	hsa-miR-1324	CLIP-seq
MIRT1231001	hsa-miR-22	CLIP-seq
MIRT1231002	hsa-miR-24	CLIP-seq
MIRT1231003	hsa-miR-2467-5p	CLIP-seq
MIRT1231004	hsa-miR-3074-5p	CLIP-seq
MIRT1231005	hsa-miR-3120-5p	CLIP-seq
MIRT1231006	hsa-miR-3126-5p	CLIP-seq
MIRT1231007	hsa-miR-3150a-3p	CLIP-seq
MIRT1231008	hsa-miR-3153	CLIP-seq
MIRT1231009	hsa-miR-3160-3p	CLIP-seq
MIRT1231010	hsa-miR-3166	CLIP-seq
MIRT1231011	hsa-miR-3175	CLIP-seq
MIRT1231012	hsa-miR-3188	CLIP-seq
MIRT1231013	hsa-miR-3609	CLIP-seq
MIRT1231014	hsa-miR-3616-5p	CLIP-seq
MIRT1231015	hsa-miR-3647-5p	CLIP-seq
MIRT1231016	hsa-miR-3929	CLIP-seq
MIRT1231017	hsa-miR-3975	CLIP-seq
MIRT1231018	hsa-miR-4271	CLIP-seq
MIRT1231019	hsa-miR-4277	CLIP-seq
MIRT1231020	hsa-miR-4287	CLIP-seq
MIRT1231021	hsa-miR-4312	CLIP-seq
MIRT1231022	hsa-miR-4319	CLIP-seq
MIRT1231023	hsa-miR-4419a	CLIP-seq
MIRT1231024	hsa-miR-4419b	CLIP-seq
MIRT1231025	hsa-miR-4469	CLIP-seq
MIRT1231026	hsa-miR-4476	CLIP-seq
MIRT1231027	hsa-miR-4477a	CLIP-seq
MIRT1231028	hsa-miR-4478	CLIP-seq
MIRT1231029	hsa-miR-4481	CLIP-seq
MIRT1231030	hsa-miR-4487	CLIP-seq
MIRT1231031	hsa-miR-4510	CLIP-seq
MIRT1231032	hsa-miR-4533	CLIP-seq
MIRT1231033	hsa-miR-4635	CLIP-seq
MIRT1231034	hsa-miR-4645-5p	CLIP-seq
MIRT1231035	hsa-miR-4649-3p	CLIP-seq
MIRT1231036	hsa-miR-4659a-5p	CLIP-seq
MIRT1231037	hsa-miR-4659b-5p	CLIP-seq
MIRT1231038	hsa-miR-4668-5p	CLIP-seq
MIRT1231039	hsa-miR-4673	CLIP-seq
MIRT1231040	hsa-miR-4685-3p	CLIP-seq
MIRT1231041	hsa-miR-4699-3p	CLIP-seq
MIRT1231042	hsa-miR-4704-5p	CLIP-seq
MIRT1231043	hsa-miR-4722-3p	CLIP-seq
MIRT1231044	hsa-miR-4725-3p	CLIP-seq
MIRT1231045	hsa-miR-4725-5p	CLIP-seq
MIRT1231046	hsa-miR-4728-5p	CLIP-seq
MIRT1231047	hsa-miR-4736	CLIP-seq
MIRT1231048	hsa-miR-4739	CLIP-seq
MIRT1231049	hsa-miR-4745-5p	CLIP-seq
MIRT1231050	hsa-miR-4751	CLIP-seq
MIRT1231051	hsa-miR-4756-3p	CLIP-seq
MIRT1231052	hsa-miR-4756-5p	CLIP-seq
MIRT1231053	hsa-miR-4763-3p	CLIP-seq
MIRT1231054	hsa-miR-4769-3p	CLIP-seq
MIRT1231055	hsa-miR-4771	CLIP-seq
MIRT1231056	hsa-miR-4780	CLIP-seq
MIRT1231057	hsa-miR-4795-3p	CLIP-seq
MIRT1231058	hsa-miR-4795-5p	CLIP-seq
MIRT1231059	hsa-miR-4797-5p	CLIP-seq
MIRT1231060	hsa-miR-485-5p	CLIP-seq
MIRT1231061	hsa-miR-491-5p	CLIP-seq
MIRT1231062	hsa-miR-504	CLIP-seq
MIRT1231063	hsa-miR-519a	CLIP-seq
MIRT1231064	hsa-miR-519b-3p	CLIP-seq
MIRT1231065	hsa-miR-519c-3p	CLIP-seq
MIRT1231066	hsa-miR-544b	CLIP-seq
MIRT1231067	hsa-miR-548ac	CLIP-seq
MIRT1231068	hsa-miR-548ae	CLIP-seq
MIRT1231069	hsa-miR-548ah	CLIP-seq
MIRT1231070	hsa-miR-548aj	CLIP-seq
MIRT1231071	hsa-miR-548am	CLIP-seq
MIRT1231072	hsa-miR-548c-3p	CLIP-seq
MIRT1231073	hsa-miR-548d-3p	CLIP-seq
MIRT1231074	hsa-miR-548x	CLIP-seq
MIRT1231075	hsa-miR-548z	CLIP-seq
MIRT1231076	hsa-miR-549	CLIP-seq
MIRT1231077	hsa-miR-558	CLIP-seq
MIRT1231078	hsa-miR-573	CLIP-seq
MIRT1231079	hsa-miR-579	CLIP-seq
MIRT1231080	hsa-miR-580	CLIP-seq
MIRT1231081	hsa-miR-607	CLIP-seq
MIRT1231082	hsa-miR-616	CLIP-seq
MIRT1231083	hsa-miR-623	CLIP-seq
MIRT1231084	hsa-miR-626	CLIP-seq
MIRT1231085	hsa-miR-656	CLIP-seq
MIRT1231086	hsa-miR-759	CLIP-seq
MIRT1231087	hsa-miR-939	CLIP-seq
MIRT1230994	hsa-miR-1207-5p	CLIP-seq
MIRT1230995	hsa-miR-1224-5p	CLIP-seq
MIRT1230996	hsa-miR-125a-5p	CLIP-seq
MIRT1230997	hsa-miR-125b	CLIP-seq
MIRT1231000	hsa-miR-1324	CLIP-seq
MIRT2067813	hsa-miR-144	CLIP-seq
MIRT2067814	hsa-miR-1912	CLIP-seq
MIRT1231002	hsa-miR-24	CLIP-seq
MIRT1231003	hsa-miR-2467-5p	CLIP-seq
MIRT1231004	hsa-miR-3074-5p	CLIP-seq
MIRT1231007	hsa-miR-3150a-3p	CLIP-seq
MIRT1231008	hsa-miR-3153	CLIP-seq
MIRT1231010	hsa-miR-3166	CLIP-seq
MIRT1231011	hsa-miR-3175	CLIP-seq
MIRT1231012	hsa-miR-3188	CLIP-seq
MIRT1231013	hsa-miR-3609	CLIP-seq
MIRT1231014	hsa-miR-3616-5p	CLIP-seq
MIRT1231015	hsa-miR-3647-5p	CLIP-seq
MIRT1231016	hsa-miR-3929	CLIP-seq
MIRT1231017	hsa-miR-3975	CLIP-seq
MIRT1231019	hsa-miR-4277	CLIP-seq
MIRT1231021	hsa-miR-4312	CLIP-seq
MIRT1231022	hsa-miR-4319	CLIP-seq
MIRT1231024	hsa-miR-4419b	CLIP-seq
MIRT1231026	hsa-miR-4476	CLIP-seq
MIRT1231028	hsa-miR-4478	CLIP-seq
MIRT1231029	hsa-miR-4481	CLIP-seq
MIRT1231032	hsa-miR-4533	CLIP-seq
MIRT1231033	hsa-miR-4635	CLIP-seq
MIRT2067815	hsa-miR-4645-3p	CLIP-seq
MIRT1231034	hsa-miR-4645-5p	CLIP-seq
MIRT1231035	hsa-miR-4649-3p	CLIP-seq
MIRT1231038	hsa-miR-4668-5p	CLIP-seq
MIRT1231039	hsa-miR-4673	CLIP-seq
MIRT2067816	hsa-miR-4685-5p	CLIP-seq
MIRT1231043	hsa-miR-4722-3p	CLIP-seq
MIRT1231045	hsa-miR-4725-5p	CLIP-seq
MIRT1231047	hsa-miR-4736	CLIP-seq
MIRT1231049	hsa-miR-4745-5p	CLIP-seq
MIRT1231050	hsa-miR-4751	CLIP-seq
MIRT1231051	hsa-miR-4756-3p	CLIP-seq
MIRT1231053	hsa-miR-4763-3p	CLIP-seq
MIRT1231055	hsa-miR-4771	CLIP-seq
MIRT1231058	hsa-miR-4795-5p	CLIP-seq
MIRT1231060	hsa-miR-485-5p	CLIP-seq
MIRT1231061	hsa-miR-491-5p	CLIP-seq
MIRT1231062	hsa-miR-504	CLIP-seq
MIRT1231063	hsa-miR-519a	CLIP-seq
MIRT1231064	hsa-miR-519b-3p	CLIP-seq
MIRT1231065	hsa-miR-519c-3p	CLIP-seq
MIRT1231066	hsa-miR-544b	CLIP-seq
MIRT1231069	hsa-miR-548ah	CLIP-seq
MIRT2067817	hsa-miR-561	CLIP-seq
MIRT1231078	hsa-miR-573	CLIP-seq
MIRT1231079	hsa-miR-579	CLIP-seq
MIRT1231082	hsa-miR-616	CLIP-seq
MIRT1231087	hsa-miR-939	CLIP-seq
MIRT1231000	hsa-miR-1324	CLIP-seq
MIRT2067813	hsa-miR-144	CLIP-seq
MIRT1231002	hsa-miR-24	CLIP-seq
MIRT1231003	hsa-miR-2467-5p	CLIP-seq
MIRT2295261	hsa-miR-3124-3p	CLIP-seq
MIRT2295262	hsa-miR-3155	CLIP-seq
MIRT2295263	hsa-miR-3155b	CLIP-seq
MIRT2295264	hsa-miR-3160-5p	CLIP-seq
MIRT2295265	hsa-miR-3187-3p	CLIP-seq
MIRT1231012	hsa-miR-3188	CLIP-seq
MIRT2295266	hsa-miR-3614-5p	CLIP-seq
MIRT2295267	hsa-miR-3667-3p	CLIP-seq
MIRT1231017	hsa-miR-3975	CLIP-seq
MIRT1231019	hsa-miR-4277	CLIP-seq
MIRT2295268	hsa-miR-4435	CLIP-seq
MIRT2067815	hsa-miR-4645-3p	CLIP-seq
MIRT2067816	hsa-miR-4685-5p	CLIP-seq
MIRT2295269	hsa-miR-4701-5p	CLIP-seq
MIRT2295270	hsa-miR-4755-3p	CLIP-seq
MIRT1231060	hsa-miR-485-5p	CLIP-seq
MIRT2295271	hsa-miR-544	CLIP-seq
MIRT2295272	hsa-miR-548s	CLIP-seq
MIRT1231080	hsa-miR-580	CLIP-seq
MIRT2295273	hsa-miR-588	CLIP-seq
MIRT1230994	hsa-miR-1207-5p	CLIP-seq
MIRT1230995	hsa-miR-1224-5p	CLIP-seq
MIRT1230996	hsa-miR-125a-5p	CLIP-seq
MIRT1230997	hsa-miR-125b	CLIP-seq
MIRT2067813	hsa-miR-144	CLIP-seq
MIRT2067814	hsa-miR-1912	CLIP-seq
MIRT1231002	hsa-miR-24	CLIP-seq
MIRT1231003	hsa-miR-2467-5p	CLIP-seq
MIRT1231012	hsa-miR-3188	CLIP-seq
MIRT1231013	hsa-miR-3609	CLIP-seq
MIRT1231016	hsa-miR-3929	CLIP-seq
MIRT1231017	hsa-miR-3975	CLIP-seq
MIRT1231019	hsa-miR-4277	CLIP-seq
MIRT1231022	hsa-miR-4319	CLIP-seq
MIRT1231024	hsa-miR-4419b	CLIP-seq
MIRT1231028	hsa-miR-4478	CLIP-seq
MIRT2067815	hsa-miR-4645-3p	CLIP-seq
MIRT1231035	hsa-miR-4649-3p	CLIP-seq
MIRT2067816	hsa-miR-4685-5p	CLIP-seq
MIRT1231045	hsa-miR-4725-5p	CLIP-seq
MIRT1231047	hsa-miR-4736	CLIP-seq
MIRT1231050	hsa-miR-4751	CLIP-seq
MIRT1231053	hsa-miR-4763-3p	CLIP-seq
MIRT1231060	hsa-miR-485-5p	CLIP-seq
MIRT1231062	hsa-miR-504	CLIP-seq
MIRT1231066	hsa-miR-544b	CLIP-seq
MIRT1231069	hsa-miR-548ah	CLIP-seq
MIRT1231079	hsa-miR-579	CLIP-seq
MIRT1231082	hsa-miR-616	CLIP-seq
MIRT1230995	hsa-miR-1224-5p	CLIP-seq
MIRT1230996	hsa-miR-125a-5p	CLIP-seq
MIRT1230997	hsa-miR-125b	CLIP-seq
MIRT2067813	hsa-miR-144	CLIP-seq
MIRT1231002	hsa-miR-24	CLIP-seq
MIRT1231003	hsa-miR-2467-5p	CLIP-seq
MIRT1231012	hsa-miR-3188	CLIP-seq
MIRT1231016	hsa-miR-3929	CLIP-seq
MIRT1231017	hsa-miR-3975	CLIP-seq
MIRT1231019	hsa-miR-4277	CLIP-seq
MIRT1231022	hsa-miR-4319	CLIP-seq
MIRT1231024	hsa-miR-4419b	CLIP-seq
MIRT1231028	hsa-miR-4478	CLIP-seq
MIRT2067815	hsa-miR-4645-3p	CLIP-seq
MIRT1231035	hsa-miR-4649-3p	CLIP-seq
MIRT2067816	hsa-miR-4685-5p	CLIP-seq
MIRT1231045	hsa-miR-4725-5p	CLIP-seq
MIRT1231050	hsa-miR-4751	CLIP-seq
MIRT1231060	hsa-miR-485-5p	CLIP-seq
MIRT1231062	hsa-miR-504	CLIP-seq
MIRT1231066	hsa-miR-544b	CLIP-seq

Gene ontology (GO) Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25484098, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006914	Process	Autophagy	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0031398	Process	Positive regulation of protein ubiquitination	IBA
GO:0031398	Process	Positive regulation of protein ubiquitination	IMP	25484098
GO:0046872	Function	Metal ion binding	IEA
GO:1901097	Process	Negative regulation of autophagosome maturation	IBA
GO:1901097	Process	Negative regulation of autophagosome maturation	IMP	25484098
GO:1902902	Process	Negative regulation of autophagosome assembly	IBA
GO:1902902	Process	Negative regulation of autophagosome assembly	IMP	25484098

Other IDs

• MIM: 612910
• HGNC: 28428
• e!Ensembl: ENSG00000040633

Protein

• UniProt ID: Q9BUL5
• Protein name: PHD finger protein 23 (PDH-containing protein JUNE-1)
• Protein function: Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvation or infecting bacteria.
• PDB: 6WXK
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00628	PHD	341 → 387	PHD-finger	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed in human tissues and various cell lines. {ECO:0000269|PubMed:25484098}.
• Sequence:

  MLEAMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPAS
  GSSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQ
  APDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRK
  KDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQA
  PPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSES
  KEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPFAGRPMIECSLCG
  TWIHLSCAKIKKTNVPDFFYCQKCKELRPEARRLGGPPKSGEP

• Sequence length: 403

Related Genes

No strongly related genes found yet for PHF23.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PHF23.