PHB2 (prohibitin 2)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 11331
• Gene name: Prohibitin 2
• Gene symbol: PHB2
• Synonyms (NCBI Gene): BAP, BCAP37, Bap37, PNAS-141, REA, hBAP, p22
• Chromosome: 12
• Chromosome location: 12p13.31

miRNA Show/Hide all (268)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028641	hsa-miR-30a-5p	Proteomics	18668040
MIRT050313	hsa-miR-25-3p	CLASH	23622248
MIRT047600	hsa-miR-10a-5p	CLASH	23622248
MIRT041559	hsa-miR-193b-3p	CLASH	23622248
MIRT525554	hsa-miR-4433b-3p	PAR-CLIP	20371350
MIRT525553	hsa-miR-1296-3p	PAR-CLIP	20371350
MIRT525552	hsa-miR-4768-3p	PAR-CLIP	20371350
MIRT525551	hsa-miR-4459	PAR-CLIP	20371350
MIRT525550	hsa-miR-4433a-3p	PAR-CLIP	20371350
MIRT525549	hsa-miR-361-3p	PAR-CLIP	20371350
MIRT525546	hsa-miR-4481	PAR-CLIP	20371350
MIRT525545	hsa-miR-4745-5p	PAR-CLIP	20371350
MIRT525544	hsa-miR-193b-5p	PAR-CLIP	20371350
MIRT525543	hsa-miR-6742-5p	PAR-CLIP	20371350
MIRT525542	hsa-miR-3170	PAR-CLIP	20371350
MIRT525541	hsa-miR-6855-5p	PAR-CLIP	20371350
MIRT525540	hsa-miR-3679-3p	PAR-CLIP	20371350
MIRT559867	hsa-miR-6875-3p	PAR-CLIP	20371350
MIRT559866	hsa-miR-4659a-3p	PAR-CLIP	20371350
MIRT559865	hsa-miR-4659b-3p	PAR-CLIP	20371350
MIRT525554	hsa-miR-4433b-3p	PAR-CLIP	20371350
MIRT525553	hsa-miR-1296-3p	PAR-CLIP	20371350
MIRT525552	hsa-miR-4768-3p	PAR-CLIP	20371350
MIRT525551	hsa-miR-4459	PAR-CLIP	20371350
MIRT525550	hsa-miR-4433a-3p	PAR-CLIP	20371350
MIRT525549	hsa-miR-361-3p	PAR-CLIP	20371350
MIRT525546	hsa-miR-4481	PAR-CLIP	20371350
MIRT525545	hsa-miR-4745-5p	PAR-CLIP	20371350
MIRT525544	hsa-miR-193b-5p	PAR-CLIP	20371350
MIRT525543	hsa-miR-6742-5p	PAR-CLIP	20371350
MIRT525542	hsa-miR-3170	PAR-CLIP	20371350
MIRT525541	hsa-miR-6855-5p	PAR-CLIP	20371350
MIRT525540	hsa-miR-3679-3p	PAR-CLIP	20371350
MIRT559867	hsa-miR-6875-3p	PAR-CLIP	20371350
MIRT559866	hsa-miR-4659a-3p	PAR-CLIP	20371350
MIRT559865	hsa-miR-4659b-3p	PAR-CLIP	20371350
MIRT525554	hsa-miR-4433b-3p	PAR-CLIP	22012620
MIRT525553	hsa-miR-1296-3p	PAR-CLIP	22012620
MIRT525552	hsa-miR-4768-3p	PAR-CLIP	22012620
MIRT525551	hsa-miR-4459	PAR-CLIP	22012620
MIRT525550	hsa-miR-4433a-3p	PAR-CLIP	22012620
MIRT525549	hsa-miR-361-3p	PAR-CLIP	22012620
MIRT525548	hsa-miR-6734-3p	PAR-CLIP	22012620
MIRT525547	hsa-miR-3667-3p	PAR-CLIP	22012620
MIRT525546	hsa-miR-4481	PAR-CLIP	22012620
MIRT525545	hsa-miR-4745-5p	PAR-CLIP	22012620
MIRT525544	hsa-miR-193b-5p	PAR-CLIP	22012620
MIRT525543	hsa-miR-6742-5p	PAR-CLIP	22012620
MIRT525542	hsa-miR-3170	PAR-CLIP	22012620
MIRT525541	hsa-miR-6855-5p	PAR-CLIP	22012620
MIRT525540	hsa-miR-3679-3p	PAR-CLIP	22012620
MIRT512385	hsa-miR-6856-3p	PAR-CLIP	23446348
MIRT512384	hsa-miR-521	PAR-CLIP	23446348
MIRT512383	hsa-miR-4323	PAR-CLIP	23446348
MIRT512382	hsa-miR-6760-3p	PAR-CLIP	23446348
MIRT512381	hsa-miR-6793-3p	PAR-CLIP	23446348
MIRT512380	hsa-miR-106b-3p	PAR-CLIP	23446348
MIRT512379	hsa-miR-539-5p	PAR-CLIP	23446348
MIRT471202	hsa-miR-548a-5p	PAR-CLIP	23592263
MIRT471201	hsa-miR-548ab	PAR-CLIP	23592263
MIRT471200	hsa-miR-548ad-5p	PAR-CLIP	23592263
MIRT471199	hsa-miR-548ae-5p	PAR-CLIP	23592263
MIRT471198	hsa-miR-548ak	PAR-CLIP	23592263
MIRT471197	hsa-miR-548am-5p	PAR-CLIP	23592263
MIRT471196	hsa-miR-548ap-5p	PAR-CLIP	23592263
MIRT471195	hsa-miR-548aq-5p	PAR-CLIP	23592263
MIRT471194	hsa-miR-548ar-5p	PAR-CLIP	23592263
MIRT471193	hsa-miR-548as-5p	PAR-CLIP	23592263
MIRT471192	hsa-miR-548au-5p	PAR-CLIP	23592263
MIRT471191	hsa-miR-548ay-5p	PAR-CLIP	23592263
MIRT471190	hsa-miR-548b-5p	PAR-CLIP	23592263
MIRT471189	hsa-miR-548bb-5p	PAR-CLIP	23592263
MIRT471188	hsa-miR-548c-5p	PAR-CLIP	23592263
MIRT471187	hsa-miR-548d-5p	PAR-CLIP	23592263
MIRT471186	hsa-miR-548h-5p	PAR-CLIP	23592263
MIRT471185	hsa-miR-548i	PAR-CLIP	23592263
MIRT471184	hsa-miR-548j-5p	PAR-CLIP	23592263
MIRT471183	hsa-miR-548o-5p	PAR-CLIP	23592263
MIRT471182	hsa-miR-548w	PAR-CLIP	23592263
MIRT471181	hsa-miR-548y	PAR-CLIP	23592263
MIRT471180	hsa-miR-559	PAR-CLIP	23592263
MIRT471179	hsa-miR-6768-5p	PAR-CLIP	23592263
MIRT471178	hsa-miR-1321	PAR-CLIP	23592263
MIRT471177	hsa-miR-4739	PAR-CLIP	23592263
MIRT471175	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT471176	hsa-miR-6085	PAR-CLIP	23592263
MIRT471174	hsa-miR-6813-5p	PAR-CLIP	23592263
MIRT471173	hsa-miR-4270	PAR-CLIP	23592263
MIRT471172	hsa-miR-4441	PAR-CLIP	23592263
MIRT471171	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT471170	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT471169	hsa-miR-765	PAR-CLIP	23592263
MIRT471168	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT471167	hsa-miR-2355-5p	PAR-CLIP	23592263
MIRT512380	hsa-miR-106b-3p	PAR-CLIP	27292025
MIRT471178	hsa-miR-1321	PAR-CLIP	27292025
MIRT471177	hsa-miR-4739	PAR-CLIP	27292025
MIRT471175	hsa-miR-4756-5p	PAR-CLIP	27292025
MIRT512384	hsa-miR-521	PAR-CLIP	27292025
MIRT512379	hsa-miR-539-5p	PAR-CLIP	27292025
MIRT512382	hsa-miR-6760-3p	PAR-CLIP	27292025
MIRT525554	hsa-miR-4433b-3p	PAR-CLIP	20371350
MIRT525553	hsa-miR-1296-3p	PAR-CLIP	20371350
MIRT525552	hsa-miR-4768-3p	PAR-CLIP	20371350
MIRT525551	hsa-miR-4459	PAR-CLIP	20371350
MIRT525550	hsa-miR-4433a-3p	PAR-CLIP	20371350
MIRT525549	hsa-miR-361-3p	PAR-CLIP	20371350
MIRT525546	hsa-miR-4481	PAR-CLIP	20371350
MIRT525545	hsa-miR-4745-5p	PAR-CLIP	20371350
MIRT525544	hsa-miR-193b-5p	PAR-CLIP	20371350
MIRT525543	hsa-miR-6742-5p	PAR-CLIP	20371350
MIRT525542	hsa-miR-3170	PAR-CLIP	20371350
MIRT525541	hsa-miR-6855-5p	PAR-CLIP	20371350
MIRT525540	hsa-miR-3679-3p	PAR-CLIP	20371350
MIRT559867	hsa-miR-6875-3p	PAR-CLIP	20371350
MIRT559866	hsa-miR-4659a-3p	PAR-CLIP	20371350
MIRT559865	hsa-miR-4659b-3p	PAR-CLIP	20371350
MIRT525554	hsa-miR-4433b-3p	PAR-CLIP	20371350
MIRT525553	hsa-miR-1296-3p	PAR-CLIP	20371350
MIRT525552	hsa-miR-4768-3p	PAR-CLIP	20371350
MIRT525551	hsa-miR-4459	PAR-CLIP	20371350
MIRT525550	hsa-miR-4433a-3p	PAR-CLIP	20371350
MIRT525549	hsa-miR-361-3p	PAR-CLIP	20371350
MIRT525546	hsa-miR-4481	PAR-CLIP	20371350
MIRT525545	hsa-miR-4745-5p	PAR-CLIP	20371350
MIRT525544	hsa-miR-193b-5p	PAR-CLIP	20371350
MIRT525543	hsa-miR-6742-5p	PAR-CLIP	20371350
MIRT525542	hsa-miR-3170	PAR-CLIP	20371350
MIRT525541	hsa-miR-6855-5p	PAR-CLIP	20371350
MIRT525540	hsa-miR-3679-3p	PAR-CLIP	20371350
MIRT559867	hsa-miR-6875-3p	PAR-CLIP	20371350
MIRT559866	hsa-miR-4659a-3p	PAR-CLIP	20371350
MIRT559865	hsa-miR-4659b-3p	PAR-CLIP	20371350
MIRT525554	hsa-miR-4433b-3p	PAR-CLIP	22012620
MIRT525553	hsa-miR-1296-3p	PAR-CLIP	22012620
MIRT525552	hsa-miR-4768-3p	PAR-CLIP	22012620
MIRT525551	hsa-miR-4459	PAR-CLIP	22012620
MIRT525550	hsa-miR-4433a-3p	PAR-CLIP	22012620
MIRT525549	hsa-miR-361-3p	PAR-CLIP	22012620
MIRT525548	hsa-miR-6734-3p	PAR-CLIP	22012620
MIRT525547	hsa-miR-3667-3p	PAR-CLIP	22012620
MIRT525546	hsa-miR-4481	PAR-CLIP	22012620
MIRT525545	hsa-miR-4745-5p	PAR-CLIP	22012620
MIRT525544	hsa-miR-193b-5p	PAR-CLIP	22012620
MIRT525543	hsa-miR-6742-5p	PAR-CLIP	22012620
MIRT525542	hsa-miR-3170	PAR-CLIP	22012620
MIRT525541	hsa-miR-6855-5p	PAR-CLIP	22012620
MIRT525540	hsa-miR-3679-3p	PAR-CLIP	22012620
MIRT512385	hsa-miR-6856-3p	PAR-CLIP	23446348
MIRT512384	hsa-miR-521	PAR-CLIP	23446348
MIRT512383	hsa-miR-4323	PAR-CLIP	23446348
MIRT512382	hsa-miR-6760-3p	PAR-CLIP	23446348
MIRT512381	hsa-miR-6793-3p	PAR-CLIP	23446348
MIRT512380	hsa-miR-106b-3p	PAR-CLIP	23446348
MIRT512379	hsa-miR-539-5p	PAR-CLIP	23446348
MIRT471202	hsa-miR-548a-5p	PAR-CLIP	23592263
MIRT471201	hsa-miR-548ab	PAR-CLIP	23592263
MIRT471200	hsa-miR-548ad-5p	PAR-CLIP	23592263
MIRT471199	hsa-miR-548ae-5p	PAR-CLIP	23592263
MIRT471198	hsa-miR-548ak	PAR-CLIP	23592263
MIRT471197	hsa-miR-548am-5p	PAR-CLIP	23592263
MIRT471196	hsa-miR-548ap-5p	PAR-CLIP	23592263
MIRT471195	hsa-miR-548aq-5p	PAR-CLIP	23592263
MIRT471194	hsa-miR-548ar-5p	PAR-CLIP	23592263
MIRT471193	hsa-miR-548as-5p	PAR-CLIP	23592263
MIRT471192	hsa-miR-548au-5p	PAR-CLIP	23592263
MIRT471191	hsa-miR-548ay-5p	PAR-CLIP	23592263
MIRT471190	hsa-miR-548b-5p	PAR-CLIP	23592263
MIRT471189	hsa-miR-548bb-5p	PAR-CLIP	23592263
MIRT471188	hsa-miR-548c-5p	PAR-CLIP	23592263
MIRT471187	hsa-miR-548d-5p	PAR-CLIP	23592263
MIRT471186	hsa-miR-548h-5p	PAR-CLIP	23592263
MIRT471185	hsa-miR-548i	PAR-CLIP	23592263
MIRT471184	hsa-miR-548j-5p	PAR-CLIP	23592263
MIRT471183	hsa-miR-548o-5p	PAR-CLIP	23592263
MIRT471182	hsa-miR-548w	PAR-CLIP	23592263
MIRT471181	hsa-miR-548y	PAR-CLIP	23592263
MIRT471180	hsa-miR-559	PAR-CLIP	23592263
MIRT471179	hsa-miR-6768-5p	PAR-CLIP	23592263
MIRT471178	hsa-miR-1321	PAR-CLIP	23592263
MIRT471177	hsa-miR-4739	PAR-CLIP	23592263
MIRT471175	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT471176	hsa-miR-6085	PAR-CLIP	23592263
MIRT471174	hsa-miR-6813-5p	PAR-CLIP	23592263
MIRT471173	hsa-miR-4270	PAR-CLIP	23592263
MIRT471172	hsa-miR-4441	PAR-CLIP	23592263
MIRT471171	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT471170	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT471169	hsa-miR-765	PAR-CLIP	23592263
MIRT471168	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT471167	hsa-miR-2355-5p	PAR-CLIP	23592263
MIRT1229368	hsa-miR-141	CLIP-seq
MIRT1229369	hsa-miR-1908	CLIP-seq
MIRT1229370	hsa-miR-200a	CLIP-seq
MIRT1229371	hsa-miR-3158-3p	CLIP-seq
MIRT1229372	hsa-miR-3180	CLIP-seq
MIRT1229373	hsa-miR-3180-3p	CLIP-seq
MIRT1229374	hsa-miR-3196	CLIP-seq
MIRT1229375	hsa-miR-3940-5p	CLIP-seq
MIRT1229376	hsa-miR-4279	CLIP-seq
MIRT1229377	hsa-miR-4446-3p	CLIP-seq
MIRT1229378	hsa-miR-4507	CLIP-seq
MIRT1229379	hsa-miR-4675	CLIP-seq
MIRT1229380	hsa-miR-4694-5p	CLIP-seq
MIRT1229381	hsa-miR-4741	CLIP-seq
MIRT1229382	hsa-miR-663	CLIP-seq
MIRT1229368	hsa-miR-141	CLIP-seq
MIRT1229370	hsa-miR-200a	CLIP-seq
MIRT2067175	hsa-miR-34b	CLIP-seq
MIRT1229376	hsa-miR-4279	CLIP-seq
MIRT2067176	hsa-miR-4489	CLIP-seq
MIRT2067177	hsa-miR-539	CLIP-seq
MIRT2067178	hsa-miR-622	CLIP-seq
MIRT1229368	hsa-miR-141	CLIP-seq
MIRT1229370	hsa-miR-200a	CLIP-seq
MIRT2067175	hsa-miR-34b	CLIP-seq
MIRT2294693	hsa-miR-4434	CLIP-seq
MIRT2294694	hsa-miR-4436b-5p	CLIP-seq
MIRT2294695	hsa-miR-4516	CLIP-seq
MIRT2294696	hsa-miR-4531	CLIP-seq
MIRT2067177	hsa-miR-539	CLIP-seq
MIRT2294697	hsa-miR-548a-3p	CLIP-seq
MIRT2294698	hsa-miR-548ae	CLIP-seq
MIRT2294699	hsa-miR-548aj	CLIP-seq
MIRT2294700	hsa-miR-548am	CLIP-seq
MIRT2294701	hsa-miR-548e	CLIP-seq
MIRT2294702	hsa-miR-548f	CLIP-seq
MIRT2294703	hsa-miR-548x	CLIP-seq
MIRT2392454	hsa-miR-1343	CLIP-seq
MIRT1229375	hsa-miR-3940-5p	CLIP-seq
MIRT2392455	hsa-miR-4461	CLIP-seq
MIRT1229378	hsa-miR-4507	CLIP-seq
MIRT2392456	hsa-miR-580	CLIP-seq
MIRT2592538	hsa-miR-1287	CLIP-seq
MIRT2592539	hsa-miR-149	CLIP-seq
MIRT1229369	hsa-miR-1908	CLIP-seq
MIRT2592540	hsa-miR-3064-5p	CLIP-seq
MIRT2592541	hsa-miR-3135b	CLIP-seq
MIRT1229371	hsa-miR-3158-3p	CLIP-seq
MIRT1229372	hsa-miR-3180	CLIP-seq
MIRT1229373	hsa-miR-3180-3p	CLIP-seq
MIRT1229374	hsa-miR-3196	CLIP-seq
MIRT2592542	hsa-miR-331-3p	CLIP-seq
MIRT2592543	hsa-miR-3652	CLIP-seq
MIRT2592544	hsa-miR-4430	CLIP-seq
MIRT1229377	hsa-miR-4446-3p	CLIP-seq
MIRT2592545	hsa-miR-4505	CLIP-seq
MIRT1229379	hsa-miR-4675	CLIP-seq
MIRT1229381	hsa-miR-4741	CLIP-seq
MIRT1229382	hsa-miR-663	CLIP-seq
MIRT2592546	hsa-miR-711	CLIP-seq
MIRT2592538	hsa-miR-1287	CLIP-seq
MIRT1229369	hsa-miR-1908	CLIP-seq
MIRT2592540	hsa-miR-3064-5p	CLIP-seq
MIRT2592541	hsa-miR-3135b	CLIP-seq
MIRT1229371	hsa-miR-3158-3p	CLIP-seq
MIRT1229372	hsa-miR-3180	CLIP-seq
MIRT1229373	hsa-miR-3180-3p	CLIP-seq
MIRT1229374	hsa-miR-3196	CLIP-seq
MIRT2592542	hsa-miR-331-3p	CLIP-seq
MIRT2592543	hsa-miR-3652	CLIP-seq
MIRT2592544	hsa-miR-4430	CLIP-seq
MIRT1229377	hsa-miR-4446-3p	CLIP-seq
MIRT2592545	hsa-miR-4505	CLIP-seq
MIRT1229379	hsa-miR-4675	CLIP-seq
MIRT1229381	hsa-miR-4741	CLIP-seq
MIRT1229382	hsa-miR-663	CLIP-seq
MIRT2592546	hsa-miR-711	CLIP-seq

Gene ontology (GO) Show/Hide all (75)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000423	Process	Mitophagy	IDA	28017329
GO:0000423	Process	Mitophagy	IEA
GO:0002639	Process	Positive regulation of immunoglobulin production	IEA
GO:0002639	Process	Positive regulation of immunoglobulin production	ISS
GO:0005515	Function	Protein binding	IPI	10359819, 11302691, 17008324, 18629613, 19116139, 19640993, 19906925, 20959514, 21328542, 21746876, 24003225, 28017329, 30021884, 31522117, 32814053
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005634	Component	Nucleus	IDA	17008324, 19116139, 20959514
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005737	Component	Cytoplasm	IDA	19116139, 32276428
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HDA	20833797
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	19906925, 31522117
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IDA	17008324
GO:0005743	Component	Mitochondrial inner membrane	IDA	18339324, 20959514, 28017329
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	ISS
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0005886	Component	Plasma membrane	IDA	22997079, 24003225
GO:0005886	Component	Plasma membrane	IEA
GO:0006606	Process	Protein import into nucleus	IDA	17008324
GO:0007005	Process	Mitochondrion organization	IBA
GO:0007005	Process	Mitochondrion organization	IEA
GO:0007005	Process	Mitochondrion organization	IMP	17008324
GO:0007005	Process	Mitochondrion organization	NAS	18339324
GO:0007062	Process	Sister chromatid cohesion	IDA	23548868
GO:0009986	Component	Cell surface	IDA	22417827, 22997079
GO:0009986	Component	Cell surface	IEA
GO:0016020	Component	Membrane	IEA
GO:0016363	Component	Nuclear matrix	IDA	21328542
GO:0016477	Process	Cell migration	IDA	24003225
GO:0030331	Function	Nuclear estrogen receptor binding	NAS	10359819
GO:0030449	Process	Regulation of complement activation	IDA	17070910
GO:0030520	Process	Estrogen receptor signaling pathway	IEA
GO:0032991	Component	Protein-containing complex	IDA	21328542
GO:0033147	Process	Negative regulation of intracellular estrogen receptor signaling pathway	IEA
GO:0033218	Function	Amide binding	IPI	19116139
GO:0033598	Process	Mammary gland epithelial cell proliferation	IEA
GO:0033600	Process	Negative regulation of mammary gland epithelial cell proliferation	IEA
GO:0035632	Component	Mitochondrial prohibitin complex	IDA	31522117
GO:0035632	Component	Mitochondrial prohibitin complex	IEA
GO:0035632	Component	Mitochondrial prohibitin complex	IPI	20959514
GO:0039529	Process	RIG-I signaling pathway	IDA	31522117
GO:0039529	Process	RIG-I signaling pathway	IEA
GO:0042113	Process	B cell activation	IEA
GO:0042113	Process	B cell activation	ISS
GO:0042802	Function	Identical protein binding	IPI	31522117
GO:0042803	Function	Protein homodimerization activity	IDA	31522117
GO:0043066	Process	Negative regulation of apoptotic process	IMP	17008324
GO:0043410	Process	Positive regulation of MAPK cascade	IDA	24003225
GO:0043433	Process	Negative regulation of DNA-binding transcription factor activity	IMP	18629613
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	10359819
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0046625	Function	Sphingolipid binding	IDA	20959514
GO:0046625	Function	Sphingolipid binding	IEA
GO:0046982	Function	Protein heterodimerization activity	IPI	28017329
GO:0050821	Process	Protein stabilization	IDA	18339324
GO:0050821	Process	Protein stabilization	IMP	17008324
GO:0051091	Process	Positive regulation of DNA-binding transcription factor activity	IDA	18629613
GO:0060744	Process	Mammary gland branching involved in thelarche	IEA
GO:0060749	Process	Mammary gland alveolus development	IEA
GO:0060762	Process	Regulation of branching involved in mammary gland duct morphogenesis	IEA
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IMP	22417827
GO:0071944	Component	Cell periphery	IDA	19906925
GO:0098800	Component	Inner mitochondrial membrane protein complex	IEA
GO:0140374	Process	Antiviral innate immune response	IDA	31522117
GO:0140374	Process	Antiviral innate immune response	IEA
GO:1900208	Process	Regulation of cardiolipin metabolic process	IEA
GO:1900208	Process	Regulation of cardiolipin metabolic process	ISS
GO:1901224	Process	Positive regulation of non-canonical NF-kappaB signal transduction	IEA
GO:1901224	Process	Positive regulation of non-canonical NF-kappaB signal transduction	ISS
GO:1904959	Process	Regulation of cytochrome-c oxidase activity	IMP	20959514

Other IDs

• MIM: 610704
• HGNC: 30306
• e!Ensembl: ENSG00000215021

Protein

• UniProt ID: Q99623
• Protein name: Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
• Protein function: Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription fac
• PDB: 6IQE , 8J4I , 8RRH
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01145	Band_7	41 → 232	SPFH domain / Band 7 family	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in myoblasts. {ECO:0000269|PubMed:17565718}.
• Sequence:

  MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQ
  DTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSM
  YQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILD
  DVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGE
  ALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK

• Sequence length: 299

Pathways

KEGG Pathway:

Mitophagy - animal

Reactome Pathway:

Processing of SMDT1

Related Genes

No strongly related genes found yet for PHB2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PHB2.