PCYOX1L (prenylcysteine oxidase 1 like)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 78991
• Gene name: Prenylcysteine oxidase 1 like
• Gene symbol: PCYOX1L
• Synonyms (NCBI Gene): -
• Chromosome: 5
• Chromosome location: 5q32

miRNA Show/Hide all (60)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016335	hsa-miR-193b-3p	Microarray	20304954
MIRT719271	hsa-miR-4662a-3p	HITS-CLIP	19536157
MIRT719270	hsa-miR-181c-3p	HITS-CLIP	19536157
MIRT719269	hsa-miR-5002-3p	HITS-CLIP	19536157
MIRT719268	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT719271	hsa-miR-4662a-3p	HITS-CLIP	19536157
MIRT719270	hsa-miR-181c-3p	HITS-CLIP	19536157
MIRT719269	hsa-miR-5002-3p	HITS-CLIP	19536157
MIRT719268	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT1218806	hsa-miR-1202	CLIP-seq
MIRT1218807	hsa-miR-1260	CLIP-seq
MIRT1218808	hsa-miR-1260b	CLIP-seq
MIRT1218809	hsa-miR-1270	CLIP-seq
MIRT1218810	hsa-miR-188-3p	CLIP-seq
MIRT1218811	hsa-miR-196a	CLIP-seq
MIRT1218812	hsa-miR-196b	CLIP-seq
MIRT1218813	hsa-miR-3156-3p	CLIP-seq
MIRT1218814	hsa-miR-3606	CLIP-seq
MIRT1218815	hsa-miR-3927	CLIP-seq
MIRT1218816	hsa-miR-3972	CLIP-seq
MIRT1218817	hsa-miR-4265	CLIP-seq
MIRT1218818	hsa-miR-4289	CLIP-seq
MIRT1218819	hsa-miR-4296	CLIP-seq
MIRT1218820	hsa-miR-4301	CLIP-seq
MIRT1218821	hsa-miR-432	CLIP-seq
MIRT1218822	hsa-miR-4322	CLIP-seq
MIRT1218823	hsa-miR-4446-5p	CLIP-seq
MIRT1218824	hsa-miR-4453	CLIP-seq
MIRT1218825	hsa-miR-4531	CLIP-seq
MIRT1218826	hsa-miR-4538	CLIP-seq
MIRT1218827	hsa-miR-4648	CLIP-seq
MIRT1218828	hsa-miR-4654	CLIP-seq
MIRT1218829	hsa-miR-4683	CLIP-seq
MIRT1218830	hsa-miR-4755-3p	CLIP-seq
MIRT1218831	hsa-miR-4769-5p	CLIP-seq
MIRT1218832	hsa-miR-620	CLIP-seq
MIRT2063313	hsa-miR-153	CLIP-seq
MIRT2063314	hsa-miR-323b-5p	CLIP-seq
MIRT2063315	hsa-miR-4307	CLIP-seq
MIRT2063316	hsa-miR-448	CLIP-seq
MIRT2063317	hsa-miR-578	CLIP-seq
MIRT2063318	hsa-miR-643	CLIP-seq
MIRT2291767	hsa-miR-1343	CLIP-seq
MIRT2291768	hsa-miR-1587	CLIP-seq
MIRT2291769	hsa-miR-1910	CLIP-seq
MIRT2291770	hsa-miR-323b-3p	CLIP-seq
MIRT2291771	hsa-miR-3691-3p	CLIP-seq
MIRT2291772	hsa-miR-378g	CLIP-seq
MIRT2291773	hsa-miR-4279	CLIP-seq
MIRT2291774	hsa-miR-4492	CLIP-seq
MIRT2291775	hsa-miR-4498	CLIP-seq
MIRT2291776	hsa-miR-455-3p	CLIP-seq
MIRT1218827	hsa-miR-4648	CLIP-seq
MIRT1218828	hsa-miR-4654	CLIP-seq
MIRT2291777	hsa-miR-4656	CLIP-seq
MIRT2291778	hsa-miR-4675	CLIP-seq
MIRT2291779	hsa-miR-4691-5p	CLIP-seq
MIRT2291780	hsa-miR-4741	CLIP-seq
MIRT1218831	hsa-miR-4769-5p	CLIP-seq
MIRT2291781	hsa-miR-762	CLIP-seq

Gene ontology (GO) Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001735	Function	Prenylcysteine oxidase activity	IBA
GO:0001735	Function	Prenylcysteine oxidase activity	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016670	Function	Oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	IEA
GO:0030327	Process	Prenylated protein catabolic process	IBA
GO:0030328	Process	Prenylcysteine catabolic process	IEA
GO:0031093	Component	Platelet alpha granule lumen	TAS
GO:0070944	Process	Neutrophil-mediated killing of bacterium	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8NBM8
• Protein name: Prenylcysteine oxidase 1-like (EC 1.8.3.-)
• Protein function: Likely to have oxidoreductase activity (Probable). Required in the mevalonate pathway to regulate prenylation and enhances the bactericidal activity of neutrophils (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07156	Prenylcys_lyase	120 → 483	Prenylcysteine lyase	Family
  PF13450	NAD_binding_8	31 → 98		Domain

• Sequence:

  MARAAPLLAALTALLAAAAAGGDAPPGKIAVVGAGIGGSAVAHFLQQHFGPRVQIDVYEK
  GTVGGRLATISVNKQHYESGAASFHSLSLHMQDFVKLLGLRHRREVVGRSAIFGGEHFML
  EETDWYLLNLFRLWWHYGISFLRLQMWVEEVMEKFMRIYKYQAHGYAFSGVEELLYSLGE
  STFVNMTQHSVAESLLQVGVTQRFIDDVVSAVLRASYGQSAAMPAFAGAMSLAGAQGSLW
  SVEGGNKLVCSGLLKLTKANVIHATVTSVTLHSTEGKALYQVAYENEVGNSSDFYDIVVI
  ATPLHLDNSSSNLTFAGFHPPIDDVQGSFQPTVVSLVHGYLNSSYFGFPDPKLFPFANIL
  TTDFPSFFCTLDNICPVNISASFRRKQPQEAAVWRVQSPKPLFRTQLKTLFRSYYSVQTA
  EWQAHPLYGSRPTLPRFALHDQLFYLNALEWAASSVEVMAVAAKNVALLAYNRWYQDLDK
  IDQKDLMHKVKTEL

• Sequence length: 494

Pathways

Reactome Pathway:

Platelet degranulation

Related Genes

No strongly related genes found yet for PCYOX1L.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PCYOX1L.