Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	56097
Gene name	Protocadherin gamma subfamily C, 5
Gene symbol	PCDHGC5
Synonyms (NCBI Gene)	PCDH-GAMMA-C5
Chromosome	5
Chromosome location	5q31.3
Summary	This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regul

miRTarBase ID	miRNA	Experiments	Reference
MIRT017026	hsa-miR-335-5p	Microarray	18185580
MIRT040776	hsa-miR-18a-3p	CLASH	23622248

12 Show/Hide all (12)

GO ID	Ontology	Definition	Evidence
GO:0005509	Function	Calcium ion binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0007155	Process	Cell adhesion	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0007399	Process	Nervous system development	IEA
GO:0016020	Component	Membrane	IEA
GO:0043524	Process	Negative regulation of neuron apoptotic process	IEA
GO:0050808	Process	Synapse organization	IBA
GO:0050808	Process	Synapse organization	IEA
GO:0050839	Function	Cell adhesion molecule binding	IBA

MIM	HGNC	e!Ensembl
606306	8718	ENSG00000240764

Q9Y5F6

Protein name

Protocadherin gamma-C5 (PCDH-gamma-C5)

Protein function

Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00028	Cadherin	247 → 341	Cadherin domain	Domain
PF00028	Cadherin	459 → 555	Cadherin domain	Domain
PF00028	Cadherin	357 → 445	Cadherin domain	Domain
PF00028	Cadherin	577 → 667	Cadherin domain	Domain
PF00028	Cadherin	138 → 233	Cadherin domain	Domain
PF08266	Cadherin_2	30 → 112	Cadherin-like	Domain
PF15974	Cadherin_tail	822 → 944	Cadherin C-terminal cytoplasmic tail, catenin-binding region	Family
PF16492	Cadherin_C_2	689 → 791	Cadherin cytoplasmic C-terminal	Family

Sequence

MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL
SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE
VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL
NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP
TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG
AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL
ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY
IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD
PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG
SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG
HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA
TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN
ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP
ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSG
SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV
PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK

Sequence length

944

Interactions

View interactions

Related Genes Genes most often co-reported with PCDHGC5 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for PCDHGC5.

Diseases Linked via Similar Genes Diseases curated for genes most similar to PCDHGC5 (see Related Genes above), that are NOT already directly curated for PCDHGC5 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to PCDHGC5.

PCDHGC5 (protocadherin gamma subfamily C, 5)

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