PCDHB16 (protocadherin beta 16)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 57717
• Gene name: Protocadherin beta 16
• Gene symbol: PCDHB16
• Synonyms (NCBI Gene): ME1, PCDH-BETA16, PCDH3X, PCDHB8a
• Chromosome: 5
• Chromosome location: 5q31.3
• Summary: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.

miRNA Show/Hide all (149)

miRTarBase ID	miRNA	Experiments	Reference
MIRT449695	hsa-miR-32-3p	PAR-CLIP	22100165
MIRT449694	hsa-miR-4635	PAR-CLIP	22100165
MIRT449693	hsa-miR-5585-3p	PAR-CLIP	22100165
MIRT449695	hsa-miR-32-3p	PAR-CLIP	22100165
MIRT449694	hsa-miR-4635	PAR-CLIP	22100165
MIRT449693	hsa-miR-5585-3p	PAR-CLIP	22100165
MIRT1217129	hsa-miR-10a	CLIP-seq
MIRT1217130	hsa-miR-10b	CLIP-seq
MIRT1217131	hsa-miR-1227	CLIP-seq
MIRT1217132	hsa-miR-1233	CLIP-seq
MIRT1217133	hsa-miR-1262	CLIP-seq
MIRT1217134	hsa-miR-1285	CLIP-seq
MIRT1217135	hsa-miR-1321	CLIP-seq
MIRT1217136	hsa-miR-135a	CLIP-seq
MIRT1217137	hsa-miR-135b	CLIP-seq
MIRT1217138	hsa-miR-154	CLIP-seq
MIRT1217139	hsa-miR-2392	CLIP-seq
MIRT1217140	hsa-miR-3148	CLIP-seq
MIRT1217141	hsa-miR-3150b-3p	CLIP-seq
MIRT1217142	hsa-miR-3187-5p	CLIP-seq
MIRT1217143	hsa-miR-339-5p	CLIP-seq
MIRT1217144	hsa-miR-3605-5p	CLIP-seq
MIRT1217145	hsa-miR-3613-3p	CLIP-seq
MIRT1217146	hsa-miR-3667-5p	CLIP-seq
MIRT1217147	hsa-miR-369-3p	CLIP-seq
MIRT1217148	hsa-miR-371-5p	CLIP-seq
MIRT1217149	hsa-miR-371b-5p	CLIP-seq
MIRT1217150	hsa-miR-374a	CLIP-seq
MIRT1217151	hsa-miR-374b	CLIP-seq
MIRT1217152	hsa-miR-374c	CLIP-seq
MIRT1217153	hsa-miR-4419a	CLIP-seq
MIRT1217154	hsa-miR-4421	CLIP-seq
MIRT1217155	hsa-miR-4433	CLIP-seq
MIRT1217156	hsa-miR-4504	CLIP-seq
MIRT1217157	hsa-miR-4510	CLIP-seq
MIRT1217158	hsa-miR-451b	CLIP-seq
MIRT1217159	hsa-miR-4633-5p	CLIP-seq
MIRT1217160	hsa-miR-4689	CLIP-seq
MIRT1217161	hsa-miR-4701-3p	CLIP-seq
MIRT1217162	hsa-miR-4725-5p	CLIP-seq
MIRT1217163	hsa-miR-4739	CLIP-seq
MIRT1217164	hsa-miR-4756-5p	CLIP-seq
MIRT1217165	hsa-miR-4779	CLIP-seq
MIRT1217166	hsa-miR-4784	CLIP-seq
MIRT1217167	hsa-miR-4793-3p	CLIP-seq
MIRT1217168	hsa-miR-504	CLIP-seq
MIRT1217169	hsa-miR-508-5p	CLIP-seq
MIRT1217170	hsa-miR-532-5p	CLIP-seq
MIRT1217171	hsa-miR-612	CLIP-seq
MIRT1217172	hsa-miR-655	CLIP-seq
MIRT1217173	hsa-miR-661	CLIP-seq
MIRT1217174	hsa-miR-766	CLIP-seq
MIRT1217175	hsa-miR-891b	CLIP-seq
MIRT1217132	hsa-miR-1233	CLIP-seq
MIRT1217134	hsa-miR-1285	CLIP-seq
MIRT1217135	hsa-miR-1321	CLIP-seq
MIRT1217136	hsa-miR-135a	CLIP-seq
MIRT1217137	hsa-miR-135b	CLIP-seq
MIRT1217139	hsa-miR-2392	CLIP-seq
MIRT2062693	hsa-miR-3122	CLIP-seq
MIRT1217142	hsa-miR-3187-5p	CLIP-seq
MIRT2062694	hsa-miR-338-5p	CLIP-seq
MIRT2062695	hsa-miR-34c-3p	CLIP-seq
MIRT1217144	hsa-miR-3605-5p	CLIP-seq
MIRT2062696	hsa-miR-3689a-3p	CLIP-seq
MIRT2062697	hsa-miR-3689c	CLIP-seq
MIRT2062698	hsa-miR-3913-5p	CLIP-seq
MIRT2062699	hsa-miR-3920	CLIP-seq
MIRT2062700	hsa-miR-3929	CLIP-seq
MIRT2062701	hsa-miR-4419b	CLIP-seq
MIRT1217155	hsa-miR-4433	CLIP-seq
MIRT2062702	hsa-miR-4478	CLIP-seq
MIRT2062703	hsa-miR-4517	CLIP-seq
MIRT1217159	hsa-miR-4633-5p	CLIP-seq
MIRT2062704	hsa-miR-4728-5p	CLIP-seq
MIRT1217163	hsa-miR-4739	CLIP-seq
MIRT1217164	hsa-miR-4756-5p	CLIP-seq
MIRT2062705	hsa-miR-4760-3p	CLIP-seq
MIRT2062706	hsa-miR-485-5p	CLIP-seq
MIRT1217170	hsa-miR-532-5p	CLIP-seq
MIRT2062707	hsa-miR-605	CLIP-seq
MIRT1217171	hsa-miR-612	CLIP-seq
MIRT1217173	hsa-miR-661	CLIP-seq
MIRT1217131	hsa-miR-1227	CLIP-seq
MIRT1217132	hsa-miR-1233	CLIP-seq
MIRT1217133	hsa-miR-1262	CLIP-seq
MIRT1217134	hsa-miR-1285	CLIP-seq
MIRT1217142	hsa-miR-3187-5p	CLIP-seq
MIRT1217155	hsa-miR-4433	CLIP-seq
MIRT1217156	hsa-miR-4504	CLIP-seq
MIRT1217161	hsa-miR-4701-3p	CLIP-seq
MIRT1217167	hsa-miR-4793-3p	CLIP-seq
MIRT1217169	hsa-miR-508-5p	CLIP-seq
MIRT1217171	hsa-miR-612	CLIP-seq
MIRT1217173	hsa-miR-661	CLIP-seq
MIRT1217174	hsa-miR-766	CLIP-seq
MIRT1217175	hsa-miR-891b	CLIP-seq
MIRT1217131	hsa-miR-1227	CLIP-seq
MIRT1217134	hsa-miR-1285	CLIP-seq
MIRT1217142	hsa-miR-3187-5p	CLIP-seq
MIRT1217155	hsa-miR-4433	CLIP-seq
MIRT1217167	hsa-miR-4793-3p	CLIP-seq
MIRT1217169	hsa-miR-508-5p	CLIP-seq
MIRT1217171	hsa-miR-612	CLIP-seq
MIRT1217173	hsa-miR-661	CLIP-seq
MIRT1217174	hsa-miR-766	CLIP-seq
MIRT1217175	hsa-miR-891b	CLIP-seq
MIRT1217129	hsa-miR-10a	CLIP-seq
MIRT1217130	hsa-miR-10b	CLIP-seq
MIRT1217134	hsa-miR-1285	CLIP-seq
MIRT2588746	hsa-miR-182	CLIP-seq
MIRT2062693	hsa-miR-3122	CLIP-seq
MIRT1217140	hsa-miR-3148	CLIP-seq
MIRT1217142	hsa-miR-3187-5p	CLIP-seq
MIRT1217143	hsa-miR-339-5p	CLIP-seq
MIRT1217145	hsa-miR-3613-3p	CLIP-seq
MIRT1217146	hsa-miR-3667-5p	CLIP-seq
MIRT1217148	hsa-miR-371-5p	CLIP-seq
MIRT1217149	hsa-miR-371b-5p	CLIP-seq
MIRT2062698	hsa-miR-3913-5p	CLIP-seq
MIRT1217154	hsa-miR-4421	CLIP-seq
MIRT2588747	hsa-miR-4470	CLIP-seq
MIRT1217159	hsa-miR-4633-5p	CLIP-seq
MIRT1217162	hsa-miR-4725-5p	CLIP-seq
MIRT1217168	hsa-miR-504	CLIP-seq
MIRT1217170	hsa-miR-532-5p	CLIP-seq
MIRT2588748	hsa-miR-548a-3p	CLIP-seq
MIRT2588749	hsa-miR-548e	CLIP-seq
MIRT2588750	hsa-miR-548f	CLIP-seq
MIRT1217171	hsa-miR-612	CLIP-seq
MIRT1217173	hsa-miR-661	CLIP-seq
MIRT1217175	hsa-miR-891b	CLIP-seq
MIRT1217129	hsa-miR-10a	CLIP-seq
MIRT1217130	hsa-miR-10b	CLIP-seq
MIRT2062693	hsa-miR-3122	CLIP-seq
MIRT1217140	hsa-miR-3148	CLIP-seq
MIRT1217143	hsa-miR-339-5p	CLIP-seq
MIRT1217145	hsa-miR-3613-3p	CLIP-seq
MIRT1217146	hsa-miR-3667-5p	CLIP-seq
MIRT2062696	hsa-miR-3689a-3p	CLIP-seq
MIRT2062697	hsa-miR-3689c	CLIP-seq
MIRT1217148	hsa-miR-371-5p	CLIP-seq
MIRT1217149	hsa-miR-371b-5p	CLIP-seq
MIRT2062698	hsa-miR-3913-5p	CLIP-seq
MIRT1217154	hsa-miR-4421	CLIP-seq
MIRT1217159	hsa-miR-4633-5p	CLIP-seq
MIRT1217162	hsa-miR-4725-5p	CLIP-seq
MIRT1217168	hsa-miR-504	CLIP-seq
MIRT1217170	hsa-miR-532-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0007155	Process	Cell adhesion	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0007268	Process	Chemical synaptic transmission	TAS	12231349
GO:0007399	Process	Nervous system development	IEA
GO:0007416	Process	Synapse assembly	TAS	12231349
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	11322959
GO:0016339	Process	Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	NAS	11322959
GO:0045202	Component	Synapse	IEA
GO:0050839	Function	Cell adhesion molecule binding	IBA

Other IDs

• MIM: 606345
• HGNC: 14546
• e!Ensembl: ENSG00000272674

Protein

• UniProt ID: Q9NRJ7
• Protein name: Protocadherin beta-16 (PCDH-beta-16) (Protocadherin-3X)
• Protein function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00028	Cadherin	247 → 338	Cadherin domain	Domain
  PF00028	Cadherin	456 → 552	Cadherin domain	Domain
  PF00028	Cadherin	139 → 233	Cadherin domain	Domain
  PF00028	Cadherin	353 → 442	Cadherin domain	Domain
  PF00028	Cadherin	575 → 663	Cadherin domain	Domain
  PF08266	Cadherin_2	30 → 112	Cadherin-like	Domain
  PF16492	Cadherin_C_2	685 → 768	Cadherin cytoplasmic C-terminal	Family

• Sequence:

  MEIGWMHNRRQRQVLVFFVLLSLSGAGAELGSYSVVEETERGSFVANLGKDLGLGLTEMS
  TRKARIISQGNKQHLQLKAQTGDLLINEKLDREELCGPTEPCILHFQVLMENPLEIFQAE
  LRVIDINDHSPMFTEKEMILKIPENSPLGTEFPLNHALDLDVGSNNVQNYKISPSSHFRV
  LIHEFRDGRKYPELVLDKELDREEEPQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAP
  EFEQPIYKVQIPENSPLGSLVATVSARDLDGGANGKISYTLFQPSEDISKTLEVNPMTGE
  VRLRKQVDFEMVTSYEVRIKATDGGGLSGKCTLLLQVVDVNDNPPQVTMSALTSPIPENS
  PEIVVAVFSVSDPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNIT
  LTVTDMGTPRLKTEHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDRDS
  GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALREFEFRVSATDRGSPA
  LSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNA
  WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSATATLHV
  LLVDGFSQPFLPLPEAAPGQTQANSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAA
  SVGRCSMPEGPFPGRLVDVSGTGTLSQSYQYEVCLTGGSETSEFKFLKPIIPNFSP

• Sequence length: 776

Related Genes

No strongly related genes found yet for PCDHB16.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PCDHB16.