PCDHB11 (protocadherin beta 11)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 56125
• Gene name: Protocadherin beta 11
• Gene symbol: PCDHB11
• Synonyms (NCBI Gene): ME2, PCDH-BETA11
• Chromosome: 5
• Chromosome location: 5q31.3
• Summary: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.

miRNA Show/Hide all (189)

miRTarBase ID	miRNA	Experiments	Reference
MIRT702081	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT702080	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT702079	hsa-miR-4786-5p	HITS-CLIP	23313552
MIRT702078	hsa-miR-769-5p	HITS-CLIP	23313552
MIRT702077	hsa-miR-1290	HITS-CLIP	23313552
MIRT702076	hsa-miR-3672	HITS-CLIP	23313552
MIRT702075	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT702074	hsa-miR-548s	HITS-CLIP	23313552
MIRT702073	hsa-miR-8055	HITS-CLIP	23313552
MIRT631627	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT631626	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT671914	hsa-miR-564	HITS-CLIP	23824327
MIRT671913	hsa-miR-4284	HITS-CLIP	23824327
MIRT671912	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT631627	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT631626	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT631625	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT631624	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT631623	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT631622	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT631621	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT631620	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT631619	hsa-miR-7977	HITS-CLIP	23824327
MIRT631618	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT631617	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT631616	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT631615	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT631614	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT631613	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT631612	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT631611	hsa-miR-3689c	HITS-CLIP	23824327
MIRT631610	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT631609	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT631608	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT631607	hsa-miR-3122	HITS-CLIP	23824327
MIRT631606	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT631605	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT631604	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT631603	hsa-miR-665	HITS-CLIP	23824327
MIRT457290	hsa-miR-302f	PAR-CLIP	23592263
MIRT457288	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT457287	hsa-miR-4740-3p	PAR-CLIP	23592263
MIRT457286	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT457285	hsa-miR-6087	PAR-CLIP	23592263
MIRT457284	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT457282	hsa-miR-1286	PAR-CLIP	23592263
MIRT457283	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT457281	hsa-miR-1273e	PAR-CLIP	23592263
MIRT446390	hsa-miR-190a-5p	PAR-CLIP	22100165
MIRT446389	hsa-miR-190b	PAR-CLIP	22100165
MIRT446390	hsa-miR-190a-5p	PAR-CLIP	22100165
MIRT446389	hsa-miR-190b	PAR-CLIP	22100165
MIRT702081	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT702080	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT702079	hsa-miR-4786-5p	HITS-CLIP	23313552
MIRT702078	hsa-miR-769-5p	HITS-CLIP	23313552
MIRT702077	hsa-miR-1290	HITS-CLIP	23313552
MIRT702076	hsa-miR-3672	HITS-CLIP	23313552
MIRT702075	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT702074	hsa-miR-548s	HITS-CLIP	23313552
MIRT702073	hsa-miR-8055	HITS-CLIP	23313552
MIRT631627	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT631626	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT671914	hsa-miR-564	HITS-CLIP	23824327
MIRT671913	hsa-miR-4284	HITS-CLIP	23824327
MIRT671912	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT631627	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT631626	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT631625	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT631624	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT631623	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT631622	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT631621	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT631620	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT631619	hsa-miR-7977	HITS-CLIP	23824327
MIRT631618	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT631617	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT631616	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT631615	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT631614	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT631613	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT631612	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT631611	hsa-miR-3689c	HITS-CLIP	23824327
MIRT631610	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT631609	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT631608	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT631607	hsa-miR-3122	HITS-CLIP	23824327
MIRT631606	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT631605	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT631604	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT631603	hsa-miR-665	HITS-CLIP	23824327
MIRT457290	hsa-miR-302f	PAR-CLIP	23592263
MIRT457288	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT457287	hsa-miR-4740-3p	PAR-CLIP	23592263
MIRT457286	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT457285	hsa-miR-6087	PAR-CLIP	23592263
MIRT457284	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT457282	hsa-miR-1286	PAR-CLIP	23592263
MIRT457283	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT457281	hsa-miR-1273e	PAR-CLIP	23592263
MIRT446390	hsa-miR-190a-5p	PAR-CLIP	22100165
MIRT446389	hsa-miR-190b	PAR-CLIP	22100165
MIRT446390	hsa-miR-190a-5p	PAR-CLIP	22100165
MIRT446389	hsa-miR-190b	PAR-CLIP	22100165
MIRT1217012	hsa-miR-1202	CLIP-seq
MIRT1217013	hsa-miR-1228	CLIP-seq
MIRT1217014	hsa-miR-2114	CLIP-seq
MIRT1217015	hsa-miR-25	CLIP-seq
MIRT1217016	hsa-miR-2964a-3p	CLIP-seq
MIRT1217017	hsa-miR-3184	CLIP-seq
MIRT1217018	hsa-miR-3194-5p	CLIP-seq
MIRT1217019	hsa-miR-32	CLIP-seq
MIRT1217020	hsa-miR-3612	CLIP-seq
MIRT1217021	hsa-miR-3622b-5p	CLIP-seq
MIRT1217022	hsa-miR-363	CLIP-seq
MIRT1217023	hsa-miR-365	CLIP-seq
MIRT1217024	hsa-miR-367	CLIP-seq
MIRT1217025	hsa-miR-3929	CLIP-seq
MIRT1217026	hsa-miR-3972	CLIP-seq
MIRT1217027	hsa-miR-423-5p	CLIP-seq
MIRT1217028	hsa-miR-4253	CLIP-seq
MIRT1217029	hsa-miR-432	CLIP-seq
MIRT1217030	hsa-miR-4325	CLIP-seq
MIRT1217031	hsa-miR-4419b	CLIP-seq
MIRT1217032	hsa-miR-4443	CLIP-seq
MIRT1217033	hsa-miR-4478	CLIP-seq
MIRT1217034	hsa-miR-4684-5p	CLIP-seq
MIRT1217035	hsa-miR-4744	CLIP-seq
MIRT1217036	hsa-miR-485-5p	CLIP-seq
MIRT1217037	hsa-miR-508-5p	CLIP-seq
MIRT1217038	hsa-miR-577	CLIP-seq
MIRT1217039	hsa-miR-650	CLIP-seq
MIRT1217040	hsa-miR-658	CLIP-seq
MIRT1217041	hsa-miR-766	CLIP-seq
MIRT1217042	hsa-miR-890	CLIP-seq
MIRT1217043	hsa-miR-92a	CLIP-seq
MIRT1217044	hsa-miR-92b	CLIP-seq
MIRT1217013	hsa-miR-1228	CLIP-seq
MIRT2062643	hsa-miR-3613-3p	CLIP-seq
MIRT1217034	hsa-miR-4684-5p	CLIP-seq
MIRT2291078	hsa-miR-1225-3p	CLIP-seq
MIRT2291079	hsa-miR-1233	CLIP-seq
MIRT2291080	hsa-miR-1827	CLIP-seq
MIRT1217014	hsa-miR-2114	CLIP-seq
MIRT2291081	hsa-miR-2467-3p	CLIP-seq
MIRT2291082	hsa-miR-3160-3p	CLIP-seq
MIRT1217020	hsa-miR-3612	CLIP-seq
MIRT1217025	hsa-miR-3929	CLIP-seq
MIRT2291083	hsa-miR-4257	CLIP-seq
MIRT1217030	hsa-miR-4325	CLIP-seq
MIRT1217031	hsa-miR-4419b	CLIP-seq
MIRT2291084	hsa-miR-4459	CLIP-seq
MIRT1217033	hsa-miR-4478	CLIP-seq
MIRT2291085	hsa-miR-4487	CLIP-seq
MIRT2291086	hsa-miR-4685-5p	CLIP-seq
MIRT2291087	hsa-miR-4695-5p	CLIP-seq
MIRT1217036	hsa-miR-485-5p	CLIP-seq
MIRT1217037	hsa-miR-508-5p	CLIP-seq
MIRT2291088	hsa-miR-526b	CLIP-seq
MIRT2291089	hsa-miR-558	CLIP-seq
MIRT2291090	hsa-miR-606	CLIP-seq
MIRT1217039	hsa-miR-650	CLIP-seq
MIRT1217041	hsa-miR-766	CLIP-seq
MIRT1217042	hsa-miR-890	CLIP-seq
MIRT1217016	hsa-miR-2964a-3p	CLIP-seq
MIRT1217034	hsa-miR-4684-5p	CLIP-seq
MIRT1217035	hsa-miR-4744	CLIP-seq
MIRT1217038	hsa-miR-577	CLIP-seq
MIRT1217034	hsa-miR-4684-5p	CLIP-seq
MIRT1217035	hsa-miR-4744	CLIP-seq
MIRT1217038	hsa-miR-577	CLIP-seq
MIRT1217017	hsa-miR-3184	CLIP-seq
MIRT1217025	hsa-miR-3929	CLIP-seq
MIRT1217027	hsa-miR-423-5p	CLIP-seq
MIRT1217031	hsa-miR-4419b	CLIP-seq
MIRT1217033	hsa-miR-4478	CLIP-seq
MIRT1217034	hsa-miR-4684-5p	CLIP-seq
MIRT1217035	hsa-miR-4744	CLIP-seq
MIRT1217036	hsa-miR-485-5p	CLIP-seq
MIRT1217038	hsa-miR-577	CLIP-seq
MIRT1217017	hsa-miR-3184	CLIP-seq
MIRT1217025	hsa-miR-3929	CLIP-seq
MIRT1217027	hsa-miR-423-5p	CLIP-seq
MIRT1217031	hsa-miR-4419b	CLIP-seq
MIRT1217033	hsa-miR-4478	CLIP-seq
MIRT1217034	hsa-miR-4684-5p	CLIP-seq
MIRT1217035	hsa-miR-4744	CLIP-seq
MIRT1217036	hsa-miR-485-5p	CLIP-seq
MIRT1217038	hsa-miR-577	CLIP-seq

Gene ontology (GO) Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	10380929
GO:0007155	Process	Cell adhesion	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007155	Process	Cell adhesion	TAS	10380929
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0007268	Process	Chemical synaptic transmission	TAS	12231349
GO:0007399	Process	Nervous system development	IEA
GO:0007399	Process	Nervous system development	TAS	10380929
GO:0007416	Process	Synapse assembly	TAS	12231349
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	11322959
GO:0016339	Process	Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	NAS	11322959
GO:0045202	Component	Synapse	IEA
GO:0050839	Function	Cell adhesion molecule binding	IBA

Other IDs

• MIM: 606337
• HGNC: 8682
• e!Ensembl: ENSG00000197479

Protein

• UniProt ID: Q9Y5F2
• Protein name: Protocadherin beta-11 (PCDH-beta-11)
• Protein function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00028	Cadherin	247 → 338	Cadherin domain	Domain
  PF00028	Cadherin	456 → 552	Cadherin domain	Domain
  PF00028	Cadherin	352 → 442	Cadherin domain	Domain
  PF00028	Cadherin	575 → 663	Cadherin domain	Domain
  PF00028	Cadherin	139 → 233	Cadherin domain	Domain
  PF08266	Cadherin_2	30 → 112	Cadherin-like	Domain
  PF16492	Cadherin_C_2	685 → 768	Cadherin cytoplasmic C-terminal	Family

• Sequence:

  MENQGTRTQQIRQVLLLFVLLGMSQAGSETWSFSVAEEMQSGSFVGNLAKDLGLKVRELS
  SRGARVVSNDKKQRLQLDINTGDLLLSETLDREELCGSIEPCVLHLQVLMQNPTQFLQIE
  LQVRDINDHSPIFSEKQMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYTISPNSHFHI
  KMRVIPDNRKYPELVLDKALDYEELPELSFILSALDGGSPPRSGTALVRVVVVDINDNSP
  EFEQAFYEVKIRENSILGSLILIVSAWDLDSGTNGEICYTFSHASEDIRKTFEINQKSGE
  ITLRAPLDFETIESYSIIIQATDGGGLFGKSTVIIHVIDVNDNAPEITVSSITSPIPENT
  PETVVMVFSIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDRESTAEYNIT
  ITVTDLGIPRLKTEHNTTVLVSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDRDS
  GTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLFALRSLDYEALQAFDFRVGATDRGSPA
  LSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNA
  WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLQV
  LLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAA
  SVGSCSVPKGPFPGHLVDVSGTGTLSQSYQYEVCLTGGSETNEFKFLKPVIPNIQAKGLG
  KNSEENSTFRNSFGFNF

• Sequence length: 797

Related Genes

No strongly related genes found yet for PCDHB11.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PCDHB11.