PCDHB10 (protocadherin beta 10)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 56126
• Gene name: Protocadherin beta 10
• Gene symbol: PCDHB10
• Synonyms (NCBI Gene): PCDH-BETA10, PCHB10
• Chromosome: 5
• Chromosome location: 5q31.3
• Summary: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.

miRNA Show/Hide all (22)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016983	hsa-miR-335-5p	Microarray	18185580
MIRT1217004	hsa-miR-338-5p	CLIP-seq
MIRT1217005	hsa-miR-3607-3p	CLIP-seq
MIRT1217006	hsa-miR-3686	CLIP-seq
MIRT1217007	hsa-miR-369-3p	CLIP-seq
MIRT1217008	hsa-miR-374a	CLIP-seq
MIRT1217009	hsa-miR-374b	CLIP-seq
MIRT1217010	hsa-miR-579	CLIP-seq
MIRT1217011	hsa-miR-633	CLIP-seq
MIRT2291073	hsa-miR-4269	CLIP-seq
MIRT2291074	hsa-miR-4514	CLIP-seq
MIRT2291075	hsa-miR-4692	CLIP-seq
MIRT2291076	hsa-miR-4742-5p	CLIP-seq
MIRT1217010	hsa-miR-579	CLIP-seq
MIRT2291077	hsa-miR-664	CLIP-seq
MIRT2687238	hsa-miR-3143	CLIP-seq
MIRT2687239	hsa-miR-3187-3p	CLIP-seq
MIRT2687240	hsa-miR-4435	CLIP-seq
MIRT2687241	hsa-miR-4701-5p	CLIP-seq
MIRT2687242	hsa-miR-4803	CLIP-seq
MIRT2687243	hsa-miR-548s	CLIP-seq
MIRT2687244	hsa-miR-588	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0007155	Process	Cell adhesion	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0007268	Process	Chemical synaptic transmission	TAS	12231349
GO:0007399	Process	Nervous system development	IEA
GO:0007416	Process	Synapse assembly	TAS	12231349
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	11322959
GO:0016339	Process	Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	NAS	11322959
GO:0045202	Component	Synapse	IEA
GO:0050839	Function	Cell adhesion molecule binding	IBA

Other IDs

• MIM: 606336
• HGNC: 8681
• e!Ensembl: ENSG00000120324

Protein

• UniProt ID: Q9UN67
• Protein name: Protocadherin beta-10 (PCDH-beta-10)
• Protein function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00028	Cadherin	456 → 552	Cadherin domain	Domain
  PF00028	Cadherin	247 → 338	Cadherin domain	Domain
  PF00028	Cadherin	138 → 233	Cadherin domain	Domain
  PF00028	Cadherin	575 → 663	Cadherin domain	Domain
  PF00028	Cadherin	352 → 442	Cadherin domain	Domain
  PF08266	Cadherin_2	30 → 112	Cadherin-like	Domain
  PF16492	Cadherin_C_2	687 → 770	Cadherin cytoplasmic C-terminal	Family

• Sequence:

  MAVRELCFPRQRQVLFLFLFWGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELA
  ARGTRVVSDDNKQYLLLDSHTGNLLTNEKLDREKLCGPKEPCMLYFQILMDDPFQIYRAE
  LRVRDINDHAPVFQDKETVLKISENTAEGTAFRLERAQDPDGGLNGIQNYTISPNSFFHI
  NISGGDEGMIYPELVLDKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAP
  QFAQALYETQAPENSPIGFLIVKVWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGE
  IFLRELLDYELVNSYKINIQAMDGGGLSARCRVLVEVLDTNDNPPELIVSSFSNSVAENS
  PETPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNIT
  ITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDS
  GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPA
  LSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNA
  WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHL
  LLVDGFSQPYLPLPEAAPAQAQAEADLLTVYLVVALASVSSLFLLSVLLFVAVRLCRRSR
  AASVGRCSVPEGPFPGHLVDVRGAETLSQSYQYEVCLTGGPGTSEFKFLKPVISDIQAQG
  PGRKGEENSTFRNSFGFNIQ

• Sequence length: 800

Related Genes

No strongly related genes found yet for PCDHB10.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PCDHB10.