PAQR3 (progestin and adipoQ receptor family member 3)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 152559
• Gene name: Progestin and adipoQ receptor family member 3
• Gene symbol: PAQR3
• Synonyms (NCBI Gene): RKTG
• Chromosome: 4
• Chromosome location: 4q21.21
• Summary: This gene encodes a seven-transmembrane protein localized in the Golgi apparatus in mammalian cells. The encoded protein belongs to the progestin and adipoQ receptor (PAQR) family. This protein functions as a tumor suppressor by inhibiting the Raf/MEK/ERK

miRNA Show/Hide all (259)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023187	hsa-miR-124-3p	Microarray	18668037
MIRT027206	hsa-miR-103a-3p	Sequencing	20371350
MIRT032065	hsa-miR-16-5p	Sequencing	20371350
MIRT511002	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT511000	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT511001	hsa-miR-5002-5p	HITS-CLIP	21572407
MIRT522027	hsa-miR-193b-5p	HITS-CLIP	21572407
MIRT510999	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT522026	hsa-miR-6737-5p	HITS-CLIP	21572407
MIRT522025	hsa-miR-6812-5p	HITS-CLIP	21572407
MIRT522024	hsa-miR-6819-5p	HITS-CLIP	21572407
MIRT522023	hsa-miR-3170	HITS-CLIP	21572407
MIRT522022	hsa-miR-6855-5p	HITS-CLIP	21572407
MIRT522021	hsa-miR-450a-2-3p	HITS-CLIP	21572407
MIRT522019	hsa-miR-4260	HITS-CLIP	21572407
MIRT522020	hsa-miR-5572	HITS-CLIP	21572407
MIRT511002	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT511000	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT510999	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT622924	hsa-miR-3920	HITS-CLIP	23824327
MIRT622923	hsa-miR-29a-5p	HITS-CLIP	23824327
MIRT622922	hsa-miR-6804-3p	HITS-CLIP	23824327
MIRT622921	hsa-miR-3192-3p	HITS-CLIP	23824327
MIRT622920	hsa-miR-500a-3p	HITS-CLIP	23824327
MIRT622919	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT622918	hsa-miR-507	HITS-CLIP	23824327
MIRT622917	hsa-miR-557	HITS-CLIP	23824327
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT511000	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT511000	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT511001	hsa-miR-5002-5p	PAR-CLIP	21572407
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT511000	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT511001	hsa-miR-5002-5p	PAR-CLIP	23446348
MIRT522027	hsa-miR-193b-5p	PAR-CLIP	23446348
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT522026	hsa-miR-6737-5p	PAR-CLIP	23446348
MIRT522025	hsa-miR-6812-5p	PAR-CLIP	23446348
MIRT522024	hsa-miR-6819-5p	PAR-CLIP	23446348
MIRT522023	hsa-miR-3170	PAR-CLIP	23446348
MIRT522022	hsa-miR-6855-5p	PAR-CLIP	23446348
MIRT522021	hsa-miR-450a-2-3p	PAR-CLIP	23446348
MIRT522019	hsa-miR-4260	PAR-CLIP	23446348
MIRT522020	hsa-miR-5572	PAR-CLIP	23446348
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT511000	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT511001	hsa-miR-5002-5p	PAR-CLIP	23446348
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT497104	hsa-miR-6757-3p	PAR-CLIP	22291592
MIRT497103	hsa-miR-875-3p	PAR-CLIP	22291592
MIRT497102	hsa-miR-3148	PAR-CLIP	22291592
MIRT497101	hsa-miR-6124	PAR-CLIP	22291592
MIRT511002	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT511000	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT511001	hsa-miR-5002-5p	HITS-CLIP	21572407
MIRT522027	hsa-miR-193b-5p	HITS-CLIP	21572407
MIRT510999	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT522026	hsa-miR-6737-5p	HITS-CLIP	21572407
MIRT522025	hsa-miR-6812-5p	HITS-CLIP	21572407
MIRT522024	hsa-miR-6819-5p	HITS-CLIP	21572407
MIRT522023	hsa-miR-3170	HITS-CLIP	21572407
MIRT522022	hsa-miR-6855-5p	HITS-CLIP	21572407
MIRT522021	hsa-miR-450a-2-3p	HITS-CLIP	21572407
MIRT522019	hsa-miR-4260	HITS-CLIP	21572407
MIRT522020	hsa-miR-5572	HITS-CLIP	21572407
MIRT511002	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT511000	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT510999	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT622924	hsa-miR-3920	HITS-CLIP	23824327
MIRT622923	hsa-miR-29a-5p	HITS-CLIP	23824327
MIRT622922	hsa-miR-6804-3p	HITS-CLIP	23824327
MIRT622921	hsa-miR-3192-3p	HITS-CLIP	23824327
MIRT622920	hsa-miR-500a-3p	HITS-CLIP	23824327
MIRT622919	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT622918	hsa-miR-507	HITS-CLIP	23824327
MIRT622917	hsa-miR-557	HITS-CLIP	23824327
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT511000	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT511000	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT511001	hsa-miR-5002-5p	PAR-CLIP	21572407
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT511000	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT511001	hsa-miR-5002-5p	PAR-CLIP	23446348
MIRT522027	hsa-miR-193b-5p	PAR-CLIP	23446348
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT522026	hsa-miR-6737-5p	PAR-CLIP	23446348
MIRT522025	hsa-miR-6812-5p	PAR-CLIP	23446348
MIRT522024	hsa-miR-6819-5p	PAR-CLIP	23446348
MIRT522023	hsa-miR-3170	PAR-CLIP	23446348
MIRT522022	hsa-miR-6855-5p	PAR-CLIP	23446348
MIRT522021	hsa-miR-450a-2-3p	PAR-CLIP	23446348
MIRT522019	hsa-miR-4260	PAR-CLIP	23446348
MIRT522020	hsa-miR-5572	PAR-CLIP	23446348
MIRT511002	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT511000	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT511001	hsa-miR-5002-5p	PAR-CLIP	23446348
MIRT510999	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT497104	hsa-miR-6757-3p	PAR-CLIP	22291592
MIRT497103	hsa-miR-875-3p	PAR-CLIP	22291592
MIRT497102	hsa-miR-3148	PAR-CLIP	22291592
MIRT497101	hsa-miR-6124	PAR-CLIP	22291592
MIRT1213331	hsa-miR-1290	CLIP-seq
MIRT1213332	hsa-miR-1292	CLIP-seq
MIRT1213333	hsa-miR-137	CLIP-seq
MIRT1213334	hsa-miR-2355-5p	CLIP-seq
MIRT1213335	hsa-miR-24	CLIP-seq
MIRT1213336	hsa-miR-300	CLIP-seq
MIRT1213337	hsa-miR-3120-3p	CLIP-seq
MIRT1213338	hsa-miR-3187-3p	CLIP-seq
MIRT1213339	hsa-miR-3647-3p	CLIP-seq
MIRT1213340	hsa-miR-3662	CLIP-seq
MIRT1213341	hsa-miR-3674	CLIP-seq
MIRT1213342	hsa-miR-381	CLIP-seq
MIRT1213343	hsa-miR-3926	CLIP-seq
MIRT1213344	hsa-miR-4330	CLIP-seq
MIRT1213345	hsa-miR-4422	CLIP-seq
MIRT1213346	hsa-miR-4435	CLIP-seq
MIRT1213347	hsa-miR-4452	CLIP-seq
MIRT1213348	hsa-miR-4471	CLIP-seq
MIRT1213349	hsa-miR-4477b	CLIP-seq
MIRT1213350	hsa-miR-4503	CLIP-seq
MIRT1213351	hsa-miR-4528	CLIP-seq
MIRT1213352	hsa-miR-4646-5p	CLIP-seq
MIRT1213353	hsa-miR-4666-3p	CLIP-seq
MIRT1213354	hsa-miR-4680-3p	CLIP-seq
MIRT1213355	hsa-miR-4698	CLIP-seq
MIRT1213356	hsa-miR-4701-5p	CLIP-seq
MIRT1213357	hsa-miR-4720-3p	CLIP-seq
MIRT1213358	hsa-miR-4727-3p	CLIP-seq
MIRT1213359	hsa-miR-4731-5p	CLIP-seq
MIRT1213360	hsa-miR-4804-3p	CLIP-seq
MIRT1213361	hsa-miR-499-3p	CLIP-seq
MIRT1213362	hsa-miR-499a-3p	CLIP-seq
MIRT1213363	hsa-miR-548s	CLIP-seq
MIRT1213364	hsa-miR-549	CLIP-seq
MIRT1213365	hsa-miR-556-3p	CLIP-seq
MIRT1213366	hsa-miR-588	CLIP-seq
MIRT1213367	hsa-miR-624	CLIP-seq
MIRT1922302	hsa-miR-3143	CLIP-seq
MIRT1922303	hsa-miR-543	CLIP-seq
MIRT2061328	hsa-miR-1229	CLIP-seq
MIRT2061329	hsa-miR-2054	CLIP-seq
MIRT2061330	hsa-miR-219-2-3p	CLIP-seq
MIRT2061331	hsa-miR-2964a-3p	CLIP-seq
MIRT2061332	hsa-miR-3129-3p	CLIP-seq
MIRT2061333	hsa-miR-3591-5p	CLIP-seq
MIRT2061334	hsa-miR-4263	CLIP-seq
MIRT2061335	hsa-miR-4280	CLIP-seq
MIRT2061336	hsa-miR-4521	CLIP-seq
MIRT1213354	hsa-miR-4680-3p	CLIP-seq
MIRT2061337	hsa-miR-4724-5p	CLIP-seq
MIRT2061338	hsa-miR-494	CLIP-seq
MIRT2061328	hsa-miR-1229	CLIP-seq
MIRT2289864	hsa-miR-1305	CLIP-seq
MIRT2289865	hsa-miR-15a	CLIP-seq
MIRT2289866	hsa-miR-15b	CLIP-seq
MIRT2289867	hsa-miR-16	CLIP-seq
MIRT2289868	hsa-miR-195	CLIP-seq
MIRT2289869	hsa-miR-323-5p	CLIP-seq
MIRT2289870	hsa-miR-330-3p	CLIP-seq
MIRT2289871	hsa-miR-3614-3p	CLIP-seq
MIRT2289872	hsa-miR-3686	CLIP-seq
MIRT2289873	hsa-miR-424	CLIP-seq
MIRT2289874	hsa-miR-4275	CLIP-seq
MIRT2289875	hsa-miR-4297	CLIP-seq
MIRT2289876	hsa-miR-4652-3p	CLIP-seq
MIRT2289877	hsa-miR-4728-3p	CLIP-seq
MIRT2289878	hsa-miR-497	CLIP-seq
MIRT2289879	hsa-miR-545	CLIP-seq
MIRT2289880	hsa-miR-590-3p	CLIP-seq
MIRT2289881	hsa-miR-607	CLIP-seq
MIRT2289882	hsa-miR-628-5p	CLIP-seq
MIRT2289869	hsa-miR-323-5p	CLIP-seq
MIRT2455861	hsa-miR-105	CLIP-seq
MIRT2455862	hsa-miR-3162-3p	CLIP-seq
MIRT2455863	hsa-miR-3671	CLIP-seq
MIRT2455864	hsa-miR-4446-5p	CLIP-seq
MIRT2455865	hsa-miR-4477a	CLIP-seq
MIRT2455866	hsa-miR-4755-5p	CLIP-seq
MIRT2455867	hsa-miR-4760-3p	CLIP-seq
MIRT2455868	hsa-miR-4775	CLIP-seq
MIRT2289880	hsa-miR-590-3p	CLIP-seq
MIRT2289881	hsa-miR-607	CLIP-seq
MIRT2587829	hsa-miR-103b	CLIP-seq
MIRT2455861	hsa-miR-105	CLIP-seq
MIRT2587830	hsa-miR-125a-3p	CLIP-seq
MIRT2587831	hsa-miR-1298	CLIP-seq
MIRT2587832	hsa-miR-298	CLIP-seq
MIRT2587833	hsa-miR-3074-3p	CLIP-seq
MIRT1213337	hsa-miR-3120-3p	CLIP-seq
MIRT2587834	hsa-miR-3127-5p	CLIP-seq
MIRT2587835	hsa-miR-3131	CLIP-seq
MIRT2587836	hsa-miR-3675-5p	CLIP-seq
MIRT2587837	hsa-miR-369-3p	CLIP-seq
MIRT2587838	hsa-miR-374a	CLIP-seq
MIRT2587839	hsa-miR-374b	CLIP-seq
MIRT2587840	hsa-miR-375	CLIP-seq
MIRT2587841	hsa-miR-377	CLIP-seq
MIRT2587842	hsa-miR-3938	CLIP-seq
MIRT2061334	hsa-miR-4263	CLIP-seq
MIRT2587843	hsa-miR-4273	CLIP-seq
MIRT2587844	hsa-miR-4274	CLIP-seq
MIRT2587845	hsa-miR-4519	CLIP-seq
MIRT2061336	hsa-miR-4521	CLIP-seq
MIRT2587846	hsa-miR-4643	CLIP-seq
MIRT2587847	hsa-miR-4677-5p	CLIP-seq
MIRT1213357	hsa-miR-4720-3p	CLIP-seq
MIRT2587848	hsa-miR-4751	CLIP-seq
MIRT2587849	hsa-miR-4795-3p	CLIP-seq
MIRT2587850	hsa-miR-486-3p	CLIP-seq
MIRT2587851	hsa-miR-487a	CLIP-seq
MIRT2587852	hsa-miR-552	CLIP-seq
MIRT2587853	hsa-miR-579	CLIP-seq
MIRT2587854	hsa-miR-611	CLIP-seq
MIRT2587855	hsa-miR-664	CLIP-seq
MIRT2587829	hsa-miR-103b	CLIP-seq
MIRT2455861	hsa-miR-105	CLIP-seq
MIRT2587830	hsa-miR-125a-3p	CLIP-seq
MIRT2587831	hsa-miR-1298	CLIP-seq
MIRT2587832	hsa-miR-298	CLIP-seq
MIRT2587833	hsa-miR-3074-3p	CLIP-seq
MIRT1213337	hsa-miR-3120-3p	CLIP-seq
MIRT2587834	hsa-miR-3127-5p	CLIP-seq
MIRT2587835	hsa-miR-3131	CLIP-seq
MIRT1213340	hsa-miR-3662	CLIP-seq
MIRT2587836	hsa-miR-3675-5p	CLIP-seq
MIRT2587837	hsa-miR-369-3p	CLIP-seq
MIRT2587838	hsa-miR-374a	CLIP-seq
MIRT2587839	hsa-miR-374b	CLIP-seq
MIRT2587840	hsa-miR-375	CLIP-seq
MIRT2587841	hsa-miR-377	CLIP-seq
MIRT2587842	hsa-miR-3938	CLIP-seq
MIRT2061334	hsa-miR-4263	CLIP-seq
MIRT2587843	hsa-miR-4273	CLIP-seq
MIRT2587844	hsa-miR-4274	CLIP-seq
MIRT2587845	hsa-miR-4519	CLIP-seq
MIRT2061336	hsa-miR-4521	CLIP-seq
MIRT2587846	hsa-miR-4643	CLIP-seq
MIRT2587847	hsa-miR-4677-5p	CLIP-seq
MIRT2687086	hsa-miR-4712-3p	CLIP-seq
MIRT1213357	hsa-miR-4720-3p	CLIP-seq
MIRT2587848	hsa-miR-4751	CLIP-seq
MIRT2587849	hsa-miR-4795-3p	CLIP-seq
MIRT2587850	hsa-miR-486-3p	CLIP-seq
MIRT2587851	hsa-miR-487a	CLIP-seq
MIRT2587852	hsa-miR-552	CLIP-seq
MIRT2587853	hsa-miR-579	CLIP-seq
MIRT2587854	hsa-miR-611	CLIP-seq
MIRT2587855	hsa-miR-664	CLIP-seq

Gene ontology (GO) Show/Hide all (31)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IDA	26311497
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0001933	Process	Negative regulation of protein phosphorylation	IDA	17724343
GO:0005515	Function	Protein binding	IPI	17724343
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IDA	17724343
GO:0005794	Component	Golgi apparatus	IEA
GO:0006607	Process	NLS-bearing protein import into nucleus	ISS
GO:0010977	Process	Negative regulation of neuron projection development	IDA	17724343
GO:0016020	Component	Membrane	IEA
GO:0032436	Process	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IEA
GO:0032436	Process	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process	ISS
GO:0033137	Process	Negative regulation of peptidyl-serine phosphorylation	IDA	17724343
GO:0034067	Process	Protein localization to Golgi apparatus	IBA
GO:0034067	Process	Protein localization to Golgi apparatus	IDA	26311497
GO:0034067	Process	Protein localization to Golgi apparatus	IPI	17724343
GO:0035357	Process	Peroxisome proliferator activated receptor signaling pathway	IDA	12955147
GO:0035359	Process	Negative regulation of peroxisome proliferator activated receptor signaling pathway	IEA
GO:0035359	Process	Negative regulation of peroxisome proliferator activated receptor signaling pathway	ISS
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	ISS
GO:0043407	Process	Negative regulation of MAP kinase activity	IDA	17724343
GO:0043495	Function	Protein-membrane adaptor activity	IDA	26311497
GO:0045542	Process	Positive regulation of cholesterol biosynthetic process	IDA	11163209, 12177166
GO:0045542	Process	Positive regulation of cholesterol biosynthetic process	IDA	26311497
GO:0045542	Process	Positive regulation of cholesterol biosynthetic process	IMP	12177166
GO:0045542	Process	Positive regulation of cholesterol biosynthetic process	ISS
GO:0051604	Process	Protein maturation	EXP	11163209
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IEA
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	ISS
GO:2000640	Process	Positive regulation of SREBP signaling pathway	IDA	26311497

Other IDs

• MIM: 614577
• HGNC: 30130
• e!Ensembl: ENSG00000163291

Protein

• UniProt ID: Q6TCH7
• Protein name: Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG)
• Protein function: Golgi-scaffold protein which modulates its interactors acitivies by anchoring them to the Golgi apparatus (PubMed:18547165, PubMed:26311497). Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi apparatus (PubMed:1854
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03006	HlyIII	64 → 289	Haemolysin-III related	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed in a range of tissues. {ECO:0000269|PubMed:16044242}.
• Sequence:

  MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPGSLKDNPYITDGYRAYLPSRLCI
  KSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCML
  CSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLA
  MILAVFFAQIHPNYLTQQWQRLRSIIFCSVSGYGVIPTLHWVWLNGGIGAPIVQDFAPRV
  IVMYMIALLAFLFYISKVPERYFPGQLNYLGSSHQIWHILAVVMLYWWHQSTVYVMQYRH
  SKPCPDYVSHL

• Sequence length: 311

Pathways

Reactome Pathway:

Negative regulation of MAPK pathway

Related Genes

No strongly related genes found yet for PAQR3.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to PAQR3.