OSGIN2 (oxidative stress induced growth inhibitor family member 2)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 734
• Gene name: Oxidative stress induced growth inhibitor family member 2
• Gene symbol: OSGIN2
• Synonyms (NCBI Gene): C8orf1, hT41
• Chromosome: 8
• Chromosome location: 8q21.3

miRNA Show/Hide all (145)

miRTarBase ID	miRNA	Experiments	Reference
MIRT1206653	hsa-miR-106a	CLIP-seq
MIRT1206654	hsa-miR-106b	CLIP-seq
MIRT1206655	hsa-miR-140-3p	CLIP-seq
MIRT1206656	hsa-miR-17	CLIP-seq
MIRT1206657	hsa-miR-20a	CLIP-seq
MIRT1206658	hsa-miR-20b	CLIP-seq
MIRT1206659	hsa-miR-3609	CLIP-seq
MIRT1206660	hsa-miR-4328	CLIP-seq
MIRT1206661	hsa-miR-4777-3p	CLIP-seq
MIRT1206662	hsa-miR-4796-3p	CLIP-seq
MIRT1206663	hsa-miR-519d	CLIP-seq
MIRT1206664	hsa-miR-548ah	CLIP-seq
MIRT1206665	hsa-miR-584	CLIP-seq
MIRT1206666	hsa-miR-875-5p	CLIP-seq
MIRT1206667	hsa-miR-93	CLIP-seq
MIRT1206653	hsa-miR-106a	CLIP-seq
MIRT1206654	hsa-miR-106b	CLIP-seq
MIRT1206668	hsa-miR-1178	CLIP-seq
MIRT1206669	hsa-miR-1244	CLIP-seq
MIRT1206670	hsa-miR-1245b-3p	CLIP-seq
MIRT1206671	hsa-miR-1278	CLIP-seq
MIRT1206672	hsa-miR-146a	CLIP-seq
MIRT1206673	hsa-miR-146b-5p	CLIP-seq
MIRT1206656	hsa-miR-17	CLIP-seq
MIRT1206674	hsa-miR-199a-5p	CLIP-seq
MIRT1206675	hsa-miR-199b-5p	CLIP-seq
MIRT1206657	hsa-miR-20a	CLIP-seq
MIRT1206658	hsa-miR-20b	CLIP-seq
MIRT1206676	hsa-miR-219-1-3p	CLIP-seq
MIRT1206677	hsa-miR-31	CLIP-seq
MIRT1206678	hsa-miR-3120-3p	CLIP-seq
MIRT1206679	hsa-miR-3121-3p	CLIP-seq
MIRT1206680	hsa-miR-3143	CLIP-seq
MIRT1206681	hsa-miR-3160-3p	CLIP-seq
MIRT1206682	hsa-miR-3163	CLIP-seq
MIRT1206683	hsa-miR-3180-5p	CLIP-seq
MIRT1206684	hsa-miR-3200-5p	CLIP-seq
MIRT1206685	hsa-miR-323b-3p	CLIP-seq
MIRT1206659	hsa-miR-3609	CLIP-seq
MIRT1206686	hsa-miR-3617	CLIP-seq
MIRT1206687	hsa-miR-3675-3p	CLIP-seq
MIRT1206688	hsa-miR-371-5p	CLIP-seq
MIRT1206689	hsa-miR-371b-5p	CLIP-seq
MIRT1206690	hsa-miR-3942-3p	CLIP-seq
MIRT1206691	hsa-miR-3976	CLIP-seq
MIRT1206692	hsa-miR-4263	CLIP-seq
MIRT1206693	hsa-miR-4307	CLIP-seq
MIRT1206694	hsa-miR-4434	CLIP-seq
MIRT1206695	hsa-miR-4487	CLIP-seq
MIRT1206696	hsa-miR-4516	CLIP-seq
MIRT1206697	hsa-miR-4528	CLIP-seq
MIRT1206698	hsa-miR-4531	CLIP-seq
MIRT1206699	hsa-miR-4659a-5p	CLIP-seq
MIRT1206700	hsa-miR-4659b-5p	CLIP-seq
MIRT1206701	hsa-miR-4668-3p	CLIP-seq
MIRT1206702	hsa-miR-4682	CLIP-seq
MIRT1206703	hsa-miR-4724-5p	CLIP-seq
MIRT1206704	hsa-miR-4742-5p	CLIP-seq
MIRT1206705	hsa-miR-4761-5p	CLIP-seq
MIRT1206706	hsa-miR-4773	CLIP-seq
MIRT1206707	hsa-miR-4776-3p	CLIP-seq
MIRT1206662	hsa-miR-4796-3p	CLIP-seq
MIRT1206708	hsa-miR-519a	CLIP-seq
MIRT1206709	hsa-miR-519b-3p	CLIP-seq
MIRT1206710	hsa-miR-519c-3p	CLIP-seq
MIRT1206663	hsa-miR-519d	CLIP-seq
MIRT1206711	hsa-miR-520a-5p	CLIP-seq
MIRT1206712	hsa-miR-525-5p	CLIP-seq
MIRT1206713	hsa-miR-543	CLIP-seq
MIRT1206664	hsa-miR-548ah	CLIP-seq
MIRT1206714	hsa-miR-548p	CLIP-seq
MIRT1206715	hsa-miR-556-5p	CLIP-seq
MIRT1206716	hsa-miR-558	CLIP-seq
MIRT1206717	hsa-miR-562	CLIP-seq
MIRT1206718	hsa-miR-571	CLIP-seq
MIRT1206719	hsa-miR-577	CLIP-seq
MIRT1206665	hsa-miR-584	CLIP-seq
MIRT1206720	hsa-miR-605	CLIP-seq
MIRT1206721	hsa-miR-641	CLIP-seq
MIRT1206722	hsa-miR-660	CLIP-seq
MIRT1206667	hsa-miR-93	CLIP-seq
MIRT2059437	hsa-miR-1269	CLIP-seq
MIRT2059438	hsa-miR-1269b	CLIP-seq
MIRT2059439	hsa-miR-1288	CLIP-seq
MIRT2059440	hsa-miR-1305	CLIP-seq
MIRT2059441	hsa-miR-141	CLIP-seq
MIRT2059442	hsa-miR-186	CLIP-seq
MIRT2059443	hsa-miR-198	CLIP-seq
MIRT2059444	hsa-miR-200a	CLIP-seq
MIRT2059445	hsa-miR-205	CLIP-seq
MIRT2059446	hsa-miR-3646	CLIP-seq
MIRT2059447	hsa-miR-421	CLIP-seq
MIRT1206693	hsa-miR-4307	CLIP-seq
MIRT2059448	hsa-miR-4515	CLIP-seq
MIRT2059449	hsa-miR-4686	CLIP-seq
MIRT2059450	hsa-miR-4740-5p	CLIP-seq
MIRT2059451	hsa-miR-4764-3p	CLIP-seq
MIRT2059452	hsa-miR-494	CLIP-seq
MIRT1206716	hsa-miR-558	CLIP-seq
MIRT2059453	hsa-miR-935	CLIP-seq
MIRT2059454	hsa-miR-944	CLIP-seq
MIRT1206669	hsa-miR-1244	CLIP-seq
MIRT2287836	hsa-miR-377	CLIP-seq
MIRT2287837	hsa-miR-4276	CLIP-seq
MIRT1206660	hsa-miR-4328	CLIP-seq
MIRT1206661	hsa-miR-4777-3p	CLIP-seq
MIRT2287838	hsa-miR-542-3p	CLIP-seq
MIRT2287839	hsa-miR-548a-5p	CLIP-seq
MIRT2287840	hsa-miR-548ab	CLIP-seq
MIRT2287841	hsa-miR-548ak	CLIP-seq
MIRT2287842	hsa-miR-548b-5p	CLIP-seq
MIRT2287843	hsa-miR-548c-5p	CLIP-seq
MIRT2287844	hsa-miR-548d-5p	CLIP-seq
MIRT2287845	hsa-miR-548h	CLIP-seq
MIRT2287846	hsa-miR-548i	CLIP-seq
MIRT2287847	hsa-miR-548j	CLIP-seq
MIRT2287848	hsa-miR-548w	CLIP-seq
MIRT2287849	hsa-miR-548y	CLIP-seq
MIRT2287850	hsa-miR-559	CLIP-seq
MIRT1206717	hsa-miR-562	CLIP-seq
MIRT1206666	hsa-miR-875-5p	CLIP-seq
MIRT1206705	hsa-miR-4761-5p	CLIP-seq
MIRT2059441	hsa-miR-141	CLIP-seq
MIRT2059444	hsa-miR-200a	CLIP-seq
MIRT2059452	hsa-miR-494	CLIP-seq
MIRT2455737	hsa-miR-2467-3p	CLIP-seq
MIRT2455738	hsa-miR-3613-3p	CLIP-seq
MIRT2455739	hsa-miR-3678-3p	CLIP-seq
MIRT2455740	hsa-miR-4257	CLIP-seq
MIRT2455741	hsa-miR-4514	CLIP-seq
MIRT2455742	hsa-miR-4692	CLIP-seq
MIRT1206704	hsa-miR-4742-5p	CLIP-seq
MIRT2455743	hsa-miR-940	CLIP-seq
MIRT2455737	hsa-miR-2467-3p	CLIP-seq
MIRT2455738	hsa-miR-3613-3p	CLIP-seq
MIRT2455739	hsa-miR-3678-3p	CLIP-seq
MIRT2455740	hsa-miR-4257	CLIP-seq
MIRT2455741	hsa-miR-4514	CLIP-seq
MIRT2455742	hsa-miR-4692	CLIP-seq
MIRT1206704	hsa-miR-4742-5p	CLIP-seq
MIRT2455743	hsa-miR-940	CLIP-seq
MIRT1206685	hsa-miR-323b-3p	CLIP-seq
MIRT1206706	hsa-miR-4773	CLIP-seq
MIRT1206719	hsa-miR-577	CLIP-seq
MIRT1206720	hsa-miR-605	CLIP-seq

Gene ontology (GO) Show/Hide all (7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004497	Function	Monooxygenase activity	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0008083	Function	Growth factor activity	IBA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0030308	Process	Negative regulation of cell growth	IBA
GO:0030496	Component	Midbody	IEA
GO:0051321	Process	Meiotic cell cycle	IEA

Other IDs

• MIM: 604598
• HGNC: 1355
• e!Ensembl: ENSG00000164823

Protein

• UniProt ID: Q9Y236
• Protein name: Oxidative stress-induced growth inhibitor 2 (hT41)
• Protein function: Monooxygenase catalytic activity (By similarity). May be involved in meiosis or the maturation of germ cells.
• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. Expressed at higher levels in testis and ovary.
• Sequence:

  MPLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILNSKLEEA
  RHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHV
  VLGKGPPGGAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKRRSLKGDRVMPEEIARYYK
  HYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKHLQIEKSNFIKRNWEIRGY
  QRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHSMPEFGAAINKGKLRGK
  VDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMM
  CTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKKIFKLSAAVVLIGSHPNLS
  FLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFALGPLVGDNFVRFLKGGALG
  VTRCLATRQKKKHLFVERGGGDGIA

• Sequence length: 505

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Lung cancer	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	36299603	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	37031243	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for OSGIN2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to OSGIN2.