OSGEPL1 (O-sialoglycoprotein endopeptidase like 1)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 64172
• Gene name: O-sialoglycoprotein endopeptidase like 1
• Gene symbol: OSGEPL1
• Synonyms (NCBI Gene): OSGEPL, Qri7
• Chromosome: 2
• Chromosome location: 2q32.2

miRNA Show/Hide all (138)

miRTarBase ID	miRNA	Experiments	Reference
MIRT000886	hsa-miR-15a-5p	Microarray	18362358
MIRT000885	hsa-miR-16-5p	Microarray	18362358
MIRT1206604	hsa-miR-129-5p	CLIP-seq
MIRT1206605	hsa-miR-1299	CLIP-seq
MIRT1206606	hsa-miR-2909	CLIP-seq
MIRT1206607	hsa-miR-3074-3p	CLIP-seq
MIRT1206608	hsa-miR-3143	CLIP-seq
MIRT1206609	hsa-miR-3162-5p	CLIP-seq
MIRT1206610	hsa-miR-335	CLIP-seq
MIRT1206611	hsa-miR-3591-5p	CLIP-seq
MIRT1206612	hsa-miR-3612	CLIP-seq
MIRT1206613	hsa-miR-4280	CLIP-seq
MIRT1206614	hsa-miR-4424	CLIP-seq
MIRT1206615	hsa-miR-4443	CLIP-seq
MIRT1206616	hsa-miR-4481	CLIP-seq
MIRT1206617	hsa-miR-4745-5p	CLIP-seq
MIRT1206618	hsa-miR-4753-3p	CLIP-seq
MIRT1206619	hsa-miR-4758-5p	CLIP-seq
MIRT1206620	hsa-miR-4761-5p	CLIP-seq
MIRT1206621	hsa-miR-4782-5p	CLIP-seq
MIRT1206622	hsa-miR-516b	CLIP-seq
MIRT1206623	hsa-miR-543	CLIP-seq
MIRT1206624	hsa-miR-584	CLIP-seq
MIRT1206625	hsa-miR-650	CLIP-seq
MIRT1206626	hsa-miR-759	CLIP-seq
MIRT1206605	hsa-miR-1299	CLIP-seq
MIRT2287826	hsa-miR-200b	CLIP-seq
MIRT2287827	hsa-miR-200c	CLIP-seq
MIRT2287828	hsa-miR-2054	CLIP-seq
MIRT2287829	hsa-miR-3145-3p	CLIP-seq
MIRT1206612	hsa-miR-3612	CLIP-seq
MIRT2287830	hsa-miR-429	CLIP-seq
MIRT1206615	hsa-miR-4443	CLIP-seq
MIRT1206620	hsa-miR-4761-5p	CLIP-seq
MIRT1206621	hsa-miR-4782-5p	CLIP-seq
MIRT1206622	hsa-miR-516b	CLIP-seq
MIRT1206625	hsa-miR-650	CLIP-seq
MIRT2287831	hsa-miR-922	CLIP-seq
MIRT2585984	hsa-miR-1228	CLIP-seq
MIRT1206605	hsa-miR-1299	CLIP-seq
MIRT2585985	hsa-miR-19a	CLIP-seq
MIRT2585986	hsa-miR-19b	CLIP-seq
MIRT2287826	hsa-miR-200b	CLIP-seq
MIRT2287827	hsa-miR-200c	CLIP-seq
MIRT2287828	hsa-miR-2054	CLIP-seq
MIRT2585987	hsa-miR-214	CLIP-seq
MIRT1206607	hsa-miR-3074-3p	CLIP-seq
MIRT2585988	hsa-miR-31	CLIP-seq
MIRT1206608	hsa-miR-3143	CLIP-seq
MIRT2287829	hsa-miR-3145-3p	CLIP-seq
MIRT1206610	hsa-miR-335	CLIP-seq
MIRT1206612	hsa-miR-3612	CLIP-seq
MIRT2585989	hsa-miR-3614-5p	CLIP-seq
MIRT2585990	hsa-miR-3619-5p	CLIP-seq
MIRT2585991	hsa-miR-3650	CLIP-seq
MIRT2585992	hsa-miR-3689a-3p	CLIP-seq
MIRT2585993	hsa-miR-3689c	CLIP-seq
MIRT2585994	hsa-miR-3940-3p	CLIP-seq
MIRT2585995	hsa-miR-3973	CLIP-seq
MIRT1206613	hsa-miR-4280	CLIP-seq
MIRT2287830	hsa-miR-429	CLIP-seq
MIRT2585996	hsa-miR-4291	CLIP-seq
MIRT2585997	hsa-miR-4293	CLIP-seq
MIRT2585998	hsa-miR-4421	CLIP-seq
MIRT1206614	hsa-miR-4424	CLIP-seq
MIRT2585999	hsa-miR-4436a	CLIP-seq
MIRT1206615	hsa-miR-4443	CLIP-seq
MIRT2586000	hsa-miR-4452	CLIP-seq
MIRT1206616	hsa-miR-4481	CLIP-seq
MIRT2586001	hsa-miR-4696	CLIP-seq
MIRT2586002	hsa-miR-4717-3p	CLIP-seq
MIRT2586003	hsa-miR-4728-5p	CLIP-seq
MIRT2586004	hsa-miR-4729	CLIP-seq
MIRT1206617	hsa-miR-4745-5p	CLIP-seq
MIRT1206619	hsa-miR-4758-5p	CLIP-seq
MIRT1206620	hsa-miR-4761-5p	CLIP-seq
MIRT1206621	hsa-miR-4782-5p	CLIP-seq
MIRT1206622	hsa-miR-516b	CLIP-seq
MIRT2586005	hsa-miR-520g	CLIP-seq
MIRT2586006	hsa-miR-520h	CLIP-seq
MIRT1206623	hsa-miR-543	CLIP-seq
MIRT2586007	hsa-miR-562	CLIP-seq
MIRT2586008	hsa-miR-593	CLIP-seq
MIRT1206625	hsa-miR-650	CLIP-seq
MIRT2586009	hsa-miR-761	CLIP-seq
MIRT2287831	hsa-miR-922	CLIP-seq
MIRT2585984	hsa-miR-1228	CLIP-seq
MIRT1206604	hsa-miR-129-5p	CLIP-seq
MIRT1206605	hsa-miR-1299	CLIP-seq
MIRT2585985	hsa-miR-19a	CLIP-seq
MIRT2585986	hsa-miR-19b	CLIP-seq
MIRT2287826	hsa-miR-200b	CLIP-seq
MIRT2287827	hsa-miR-200c	CLIP-seq
MIRT2287828	hsa-miR-2054	CLIP-seq
MIRT2585987	hsa-miR-214	CLIP-seq
MIRT1206606	hsa-miR-2909	CLIP-seq
MIRT1206607	hsa-miR-3074-3p	CLIP-seq
MIRT2585988	hsa-miR-31	CLIP-seq
MIRT1206608	hsa-miR-3143	CLIP-seq
MIRT2287829	hsa-miR-3145-3p	CLIP-seq
MIRT1206609	hsa-miR-3162-5p	CLIP-seq
MIRT1206610	hsa-miR-335	CLIP-seq
MIRT1206612	hsa-miR-3612	CLIP-seq
MIRT2585989	hsa-miR-3614-5p	CLIP-seq
MIRT2585990	hsa-miR-3619-5p	CLIP-seq
MIRT2585991	hsa-miR-3650	CLIP-seq
MIRT2585992	hsa-miR-3689a-3p	CLIP-seq
MIRT2585993	hsa-miR-3689c	CLIP-seq
MIRT2585994	hsa-miR-3940-3p	CLIP-seq
MIRT2585995	hsa-miR-3973	CLIP-seq
MIRT1206613	hsa-miR-4280	CLIP-seq
MIRT2287830	hsa-miR-429	CLIP-seq
MIRT2585996	hsa-miR-4291	CLIP-seq
MIRT2585997	hsa-miR-4293	CLIP-seq
MIRT2585998	hsa-miR-4421	CLIP-seq
MIRT1206614	hsa-miR-4424	CLIP-seq
MIRT2585999	hsa-miR-4436a	CLIP-seq
MIRT1206615	hsa-miR-4443	CLIP-seq
MIRT2586000	hsa-miR-4452	CLIP-seq
MIRT1206616	hsa-miR-4481	CLIP-seq
MIRT2586001	hsa-miR-4696	CLIP-seq
MIRT2586002	hsa-miR-4717-3p	CLIP-seq
MIRT2586003	hsa-miR-4728-5p	CLIP-seq
MIRT2586004	hsa-miR-4729	CLIP-seq
MIRT1206617	hsa-miR-4745-5p	CLIP-seq
MIRT1206618	hsa-miR-4753-3p	CLIP-seq
MIRT1206619	hsa-miR-4758-5p	CLIP-seq
MIRT1206620	hsa-miR-4761-5p	CLIP-seq
MIRT1206621	hsa-miR-4782-5p	CLIP-seq
MIRT1206622	hsa-miR-516b	CLIP-seq
MIRT2586005	hsa-miR-520g	CLIP-seq
MIRT2586006	hsa-miR-520h	CLIP-seq
MIRT1206623	hsa-miR-543	CLIP-seq
MIRT2586007	hsa-miR-562	CLIP-seq
MIRT2586008	hsa-miR-593	CLIP-seq
MIRT1206625	hsa-miR-650	CLIP-seq
MIRT2586009	hsa-miR-761	CLIP-seq
MIRT2287831	hsa-miR-922	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002949	Process	TRNA threonylcarbamoyladenosine modification	IDA	29760464, 32047918
GO:0002949	Process	TRNA threonylcarbamoyladenosine modification	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	29760464
GO:0005739	Component	Mitochondrion	IDA
GO:0005739	Component	Mitochondrion	IEA
GO:0008033	Process	TRNA processing	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016746	Function	Acyltransferase activity	IEA
GO:0016747	Function	Acyltransferase activity, transferring groups other than amino-acyl groups	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0061711	Function	TRNA N(6)-L-threonylcarbamoyladenine synthase activity	IDA	29760464, 32047918
GO:0061711	Function	TRNA N(6)-L-threonylcarbamoyladenine synthase activity	IEA

Other IDs

• MIM: 619634
• HGNC: 23075
• e!Ensembl: ENSG00000128694

Protein

• UniProt ID: Q9H4B0
• Protein name: tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase-like protein 1) (OSGEP-like protein 1) (t(6)A37 threonylcarbamoyladenosine biosynthes
• Protein function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00814	TsaD	59 → 365	tRNA N6-adenosine threonylcarbamoyltransferase	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed, with maximum expression in pituitary gland, prostate, rectum and uterus. {ECO:0000269|PubMed:19694617}.
• Sequence:

  MLILTKTAGVFFKPSKRKVYEFLRSFNFHPGTLFLHKIVLGIETSCDDTAAAVVDETGNV
  LGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQEALSASGVSPSDLSAIATTIKPGL
  ALSLGVGLSFSLQLVGQLKKPFIPIHHMEAHALTIRLTNKVEFPFLVLLISGGHCLLALV
  QGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKQGNRFHFDIK
  PPLHHAKNCDFSFTGLQHVTDKIIMKKEKEEGIEKGQILSSAADIAATVQHTMACHLVKR
  THRAILFCKQRDLLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLCPPPRLCTDNG
  IMIAWNGIERLRAGLGILHDIEGIRYEPKCPLGVDISKEVGEASIKVPQLKMEI

• Sequence length: 414

Related Genes

No strongly related genes found yet for OSGEPL1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to OSGEPL1.