NXPE2 (neurexophilin and PC-esterase domain family member 2)

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Gene Gene information from NCBI Gene database.
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Entrez ID 120406
Gene name Neurexophilin and PC-esterase domain family member 2
Gene symbol NXPE2
Synonyms (NCBI Gene)
FAM55B
Chromosome 11
Chromosome location 11q23.2-q23.3
miRNA miRNA information provided by mirtarbase database.
18 Show/Hide all (18)
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miRTarBase ID miRNA Experiments Reference
MIRT625839 hsa-miR-1306-5p HITS-CLIP 23824327
MIRT625838 hsa-miR-6890-3p HITS-CLIP 23824327
MIRT625837 hsa-miR-660-3p HITS-CLIP 23824327
MIRT625836 hsa-miR-1304-3p HITS-CLIP 23824327
MIRT625835 hsa-miR-3653-5p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
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GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 24550280, 32296183
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96DL1
Protein name NXPE family member 2 (Protein FAM55B)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06312 Neurexophilin 93 → 281 Neurexophilin Family
Sequence 
MVEKILIHRILTLFPNAIARKLLLMLTFILIFWIIYLASKDHTKFSFNLENHIILNQGNI
FKKYSHSETPLCPAVSPKETELRIKDIMEKLDQQIPPRPFTHVNTTTSATHSTATILNPQ
DTYCRGDQLDILLEVRDHLGHRKQYGGDFLRARMYSTALMAGASGKVTDFNNGTYLVSFT
LFWEGQVSLSLLLIHPSEGVSALWRARNQGCDRIIFTGLFANRSSNVFTECGLTLNTNAE
LCQYMDDRDQEAFYCVRPQHMPCEALTHMTTRTRNISYLSKEEWRLFHRSNIGVEMMKNF
TPIEVIPCNKSENIKKNCQIGMKTPFPSGYTLKKMWITAFCKQIKFNETKNINDCLERKL
IYLMGDSTLHQWIYYLQKAVKTLKYFDHHGAGIFKTHVLLDVERHILIQWKKHGHPFVTK
KLFSVKDENYIPREIDQVAGDKNTAIVITLGQHFRPFPINIFIRRAINIQKAIERLFLRS
PETKVILKTENTREIEQNAEMFSDFHGYIQNLIIRDIFVDLNVGIIDAWDMTIAYCTNNA
HPPDYVIQNQIGMFLNYIC
Sequence length 559
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
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Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
MAJOR DEPRESSIVE DISORDER — GWAS catalog 34734193
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
PARKINSON DISEASE — GWAS catalog 33111402
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Malignant neoplasm of stomach Stomach Neoplasms BEFREE 31773340
★★★★★
★☆☆☆☆
Found in Text Mining only
Stomach Carcinoma Stomach Carcinoma BEFREE 31773340
★★★★★
★☆☆☆☆
Found in Text Mining only
Stomach Neoplasms Stomach neoplasms Pubtator 31773340 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only

No strongly related genes found yet for NXPE2.

No additional diseases found yet through genes similar to NXPE2.