Log in to save this analysis

Save This Analysis

Gene Gene information from NCBI Gene database.
Entrez ID 254552
Gene name Nudix hydrolase 8
Gene symbol NUDT8
Synonyms (NCBI Gene)
-
Chromosome 11
Chromosome location 11q13.2
miRNA miRNA information provided by mirtarbase database.
104 Show/Hide all (104)
miRTarBase ID miRNA Experiments Reference
MIRT051612 hsa-let-7e-5p CLASH 23622248
MIRT440076 hsa-miR-142-3p HITS-CLIP 22473208
MIRT440076 hsa-miR-142-3p HITS-CLIP 22473208
MIRT1198364 hsa-miR-103a CLIP-seq
MIRT1198365 hsa-miR-107 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15 Show/Hide all (15)
GO ID Ontology Definition Evidence Reference
GO:0000287 Function Magnesium ion binding ISS
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IEA
GO:0005739 Component Mitochondrion ISS
GO:0010945 Function Coenzyme A diphosphatase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8WV74
Protein name Mitochondrial coenzyme A diphosphatase NUDT8 (EC 3.6.1.-) (EC 3.6.1.77) (Nucleoside diphosphate-linked moiety X motif 8) (Nudix motif 8)
Protein function Acyl-CoA diphosphatase that mediates the hydrolysis of a wide range of CoA and CoA esters yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products (By similarity). Hydrolyzes short- and medium-chain acyl-CoAs, exhibi
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00293 NUDIX 29 → 159 NUDIX domain Domain
Sequence
MLPDCLSAEGELRCRRLLAGATARLRARPASAAVLVPLCSVRGVPALLYTLRSSRLTGRH
KGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVLAG
VGPLDPQSLRPNSEEVDEVFALPLAHLLQTQNQGYTHFC
RGGHFRYTLPVFLHGPHRVWG
LTAVITEFALQLLAPGTYQPRLAGLTCSGAEGLARPKQPLASPCQASSTPGLNKGL
Sequence length 236
Interactions View interactions