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Gene Gene information from NCBI Gene database.
Entrez ID 84304
Gene name Nudix hydrolase 22
Gene symbol NUDT22
Synonyms (NCBI Gene)
-
Chromosome 11
Chromosome location 11q13.1
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
8 Show/Hide all (8)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 31515488, 32296183
GO:0005654 Component Nucleoplasm IDA
GO:0008768 Function UDP-sugar diphosphatase activity IDA 29413322
GO:0008768 Function UDP-sugar diphosphatase activity IEA
GO:0016787 Function Hydrolase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BRQ3
Protein name Uridine diphosphate glucose pyrophosphatase NUDT22 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 22) (Nudix motif 22)
Protein function Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP. Preferred substrate is UDP-glucose.
PDB 5LF9 , 5LOR , 5LOU , 5R50 , 5R51 , 5R52 , 5R53 , 5R54 , 5R55 , 5R56 , 5R57 , 5R58 , 5R59 , 5R5A , 5R5B , 5R5C , 5R5D , 5R5E , 5R5F , 5R5G , 5R5H , 5R5I , 5R5J , 5R5K , 5R5L , 5R5M , 5R5N , 5R5O , 5R5P , 5R5Q , 5R5R , 5R5S , 5RKZ
Family and domains
Sequence
MDPEVTLLLQCPGGGLPQEQIQAELSPAHDRRPLPGGDEAITAIWETRLKAQPWLFDAPK
FRLHSATLAPIGSRGPQLLLRLGLTSYRDFLGTNWSSSAAWLRQQGATDWGDTQAYLADP
LGVGAALATADDFLVFLRRSRQVAEAPGLVDVPGGHPEPQALCPGGSPQHQDLAGQLVVH
ELFSSVLQEICDEVNLPLLTLSQPLLLGIARNETSAGRASAEFYVQCSLTSEQVRKHYLS
GGPEAHESTGIFFVETQNVQRLLETEMWAELCPSAKGAIILYNRVQGSPTGAALGSPALL
PPL
Sequence length 303
Interactions View interactions