NUDT16L1 (nudix hydrolase 16 like 1)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 84309
• Gene name: Nudix hydrolase 16 like 1
• Gene symbol: NUDT16L1
• Synonyms (NCBI Gene): SDOS, TIRR
• Chromosome: 16
• Chromosome location: 16p13.3

miRNA Show/Hide all (177)

miRTarBase ID	miRNA	Experiments	Reference
MIRT709244	hsa-miR-7112-5p	HITS-CLIP	19536157
MIRT709243	hsa-miR-4279	HITS-CLIP	19536157
MIRT709244	hsa-miR-7112-5p	HITS-CLIP	19536157
MIRT709243	hsa-miR-4279	HITS-CLIP	19536157
MIRT1197743	hsa-miR-1291	CLIP-seq
MIRT1197744	hsa-miR-1292	CLIP-seq
MIRT1197745	hsa-miR-1302	CLIP-seq
MIRT1197746	hsa-miR-1343	CLIP-seq
MIRT1197747	hsa-miR-139-3p	CLIP-seq
MIRT1197748	hsa-miR-144	CLIP-seq
MIRT1197749	hsa-miR-149	CLIP-seq
MIRT1197750	hsa-miR-193a-5p	CLIP-seq
MIRT1197751	hsa-miR-320e	CLIP-seq
MIRT1197752	hsa-miR-361-3p	CLIP-seq
MIRT1197753	hsa-miR-3685	CLIP-seq
MIRT1197754	hsa-miR-4269	CLIP-seq
MIRT1197755	hsa-miR-4292	CLIP-seq
MIRT1197756	hsa-miR-4298	CLIP-seq
MIRT1197757	hsa-miR-4308	CLIP-seq
MIRT1197758	hsa-miR-4471	CLIP-seq
MIRT1197759	hsa-miR-4477a	CLIP-seq
MIRT1197760	hsa-miR-4514	CLIP-seq
MIRT1197761	hsa-miR-4646-5p	CLIP-seq
MIRT1197762	hsa-miR-4648	CLIP-seq
MIRT1197763	hsa-miR-4654	CLIP-seq
MIRT1197764	hsa-miR-4679	CLIP-seq
MIRT1197765	hsa-miR-4684-5p	CLIP-seq
MIRT1197766	hsa-miR-4692	CLIP-seq
MIRT1197767	hsa-miR-4732-3p	CLIP-seq
MIRT1197768	hsa-miR-4742-5p	CLIP-seq
MIRT1197769	hsa-miR-4769-5p	CLIP-seq
MIRT1197770	hsa-miR-4795-3p	CLIP-seq
MIRT1197771	hsa-miR-483-3p	CLIP-seq
MIRT1197772	hsa-miR-634	CLIP-seq
MIRT1197773	hsa-miR-760	CLIP-seq
MIRT1197774	hsa-miR-943	CLIP-seq
MIRT2057223	hsa-miR-1182	CLIP-seq
MIRT2057224	hsa-miR-1225-3p	CLIP-seq
MIRT2057225	hsa-miR-1233	CLIP-seq
MIRT1197743	hsa-miR-1291	CLIP-seq
MIRT2057226	hsa-miR-132	CLIP-seq
MIRT1197746	hsa-miR-1343	CLIP-seq
MIRT1197747	hsa-miR-139-3p	CLIP-seq
MIRT1197748	hsa-miR-144	CLIP-seq
MIRT1197749	hsa-miR-149	CLIP-seq
MIRT2057227	hsa-miR-1827	CLIP-seq
MIRT1197750	hsa-miR-193a-5p	CLIP-seq
MIRT2057228	hsa-miR-212	CLIP-seq
MIRT2057229	hsa-miR-24	CLIP-seq
MIRT1197751	hsa-miR-320e	CLIP-seq
MIRT2057230	hsa-miR-335	CLIP-seq
MIRT2057231	hsa-miR-3545-3p	CLIP-seq
MIRT1197752	hsa-miR-361-3p	CLIP-seq
MIRT1197753	hsa-miR-3685	CLIP-seq
MIRT2057232	hsa-miR-4284	CLIP-seq
MIRT2057233	hsa-miR-4303	CLIP-seq
MIRT1197759	hsa-miR-4477a	CLIP-seq
MIRT2057234	hsa-miR-4539	CLIP-seq
MIRT1197764	hsa-miR-4679	CLIP-seq
MIRT1197765	hsa-miR-4684-5p	CLIP-seq
MIRT2057235	hsa-miR-4779	CLIP-seq
MIRT2057236	hsa-miR-4793-5p	CLIP-seq
MIRT1197770	hsa-miR-4795-3p	CLIP-seq
MIRT1197771	hsa-miR-483-3p	CLIP-seq
MIRT1197772	hsa-miR-634	CLIP-seq
MIRT1197773	hsa-miR-760	CLIP-seq
MIRT2057237	hsa-miR-892b	CLIP-seq
MIRT2057238	hsa-miR-940	CLIP-seq
MIRT2285666	hsa-miR-1180	CLIP-seq
MIRT2285667	hsa-miR-1226	CLIP-seq
MIRT2285668	hsa-miR-1227	CLIP-seq
MIRT1197743	hsa-miR-1291	CLIP-seq
MIRT2285669	hsa-miR-1915	CLIP-seq
MIRT2285670	hsa-miR-296-5p	CLIP-seq
MIRT2285671	hsa-miR-3194-3p	CLIP-seq
MIRT2285672	hsa-miR-3613-5p	CLIP-seq
MIRT2285673	hsa-miR-3620	CLIP-seq
MIRT2285674	hsa-miR-376c	CLIP-seq
MIRT2285675	hsa-miR-3973	CLIP-seq
MIRT2285676	hsa-miR-4267	CLIP-seq
MIRT1197754	hsa-miR-4269	CLIP-seq
MIRT2057233	hsa-miR-4303	CLIP-seq
MIRT1197760	hsa-miR-4514	CLIP-seq
MIRT2285677	hsa-miR-4524	CLIP-seq
MIRT2285678	hsa-miR-4682	CLIP-seq
MIRT2285679	hsa-miR-4690-5p	CLIP-seq
MIRT1197766	hsa-miR-4692	CLIP-seq
MIRT2285680	hsa-miR-4715-3p	CLIP-seq
MIRT2285681	hsa-miR-4728-5p	CLIP-seq
MIRT1197767	hsa-miR-4732-3p	CLIP-seq
MIRT1197768	hsa-miR-4742-5p	CLIP-seq
MIRT2285682	hsa-miR-4786-3p	CLIP-seq
MIRT2285683	hsa-miR-548a-5p	CLIP-seq
MIRT2285684	hsa-miR-548ab	CLIP-seq
MIRT2285685	hsa-miR-548ak	CLIP-seq
MIRT2285686	hsa-miR-548b-5p	CLIP-seq
MIRT2285687	hsa-miR-548c-5p	CLIP-seq
MIRT2285688	hsa-miR-548d-5p	CLIP-seq
MIRT2285689	hsa-miR-548h	CLIP-seq
MIRT2285690	hsa-miR-548i	CLIP-seq
MIRT2285691	hsa-miR-548j	CLIP-seq
MIRT2285692	hsa-miR-548w	CLIP-seq
MIRT2285693	hsa-miR-548y	CLIP-seq
MIRT2285694	hsa-miR-559	CLIP-seq
MIRT2583802	hsa-miR-127-5p	CLIP-seq
MIRT1197744	hsa-miR-1292	CLIP-seq
MIRT1197745	hsa-miR-1302	CLIP-seq
MIRT1197746	hsa-miR-1343	CLIP-seq
MIRT1197747	hsa-miR-139-3p	CLIP-seq
MIRT1197750	hsa-miR-193a-5p	CLIP-seq
MIRT2583803	hsa-miR-3182	CLIP-seq
MIRT2583804	hsa-miR-342-5p	CLIP-seq
MIRT2583805	hsa-miR-3545-5p	CLIP-seq
MIRT2583806	hsa-miR-377	CLIP-seq
MIRT2583807	hsa-miR-3910	CLIP-seq
MIRT1197754	hsa-miR-4269	CLIP-seq
MIRT2583808	hsa-miR-4281	CLIP-seq
MIRT1197755	hsa-miR-4292	CLIP-seq
MIRT1197756	hsa-miR-4298	CLIP-seq
MIRT2057233	hsa-miR-4303	CLIP-seq
MIRT1197757	hsa-miR-4308	CLIP-seq
MIRT1197758	hsa-miR-4471	CLIP-seq
MIRT2583809	hsa-miR-4481	CLIP-seq
MIRT1197760	hsa-miR-4514	CLIP-seq
MIRT1197761	hsa-miR-4646-5p	CLIP-seq
MIRT1197762	hsa-miR-4648	CLIP-seq
MIRT2583810	hsa-miR-4651	CLIP-seq
MIRT1197763	hsa-miR-4654	CLIP-seq
MIRT2583811	hsa-miR-4664-5p	CLIP-seq
MIRT1197764	hsa-miR-4679	CLIP-seq
MIRT2285678	hsa-miR-4682	CLIP-seq
MIRT1197765	hsa-miR-4684-5p	CLIP-seq
MIRT2583812	hsa-miR-4691-5p	CLIP-seq
MIRT1197766	hsa-miR-4692	CLIP-seq
MIRT1197768	hsa-miR-4742-5p	CLIP-seq
MIRT2583813	hsa-miR-4745-5p	CLIP-seq
MIRT2583814	hsa-miR-4758-5p	CLIP-seq
MIRT1197769	hsa-miR-4769-5p	CLIP-seq
MIRT2057235	hsa-miR-4779	CLIP-seq
MIRT1197771	hsa-miR-483-3p	CLIP-seq
MIRT2583815	hsa-miR-608	CLIP-seq
MIRT1197772	hsa-miR-634	CLIP-seq
MIRT2583816	hsa-miR-933	CLIP-seq
MIRT2583802	hsa-miR-127-5p	CLIP-seq
MIRT1197744	hsa-miR-1292	CLIP-seq
MIRT1197745	hsa-miR-1302	CLIP-seq
MIRT1197746	hsa-miR-1343	CLIP-seq
MIRT2583803	hsa-miR-3182	CLIP-seq
MIRT2583804	hsa-miR-342-5p	CLIP-seq
MIRT2583805	hsa-miR-3545-5p	CLIP-seq
MIRT2583806	hsa-miR-377	CLIP-seq
MIRT2583807	hsa-miR-3910	CLIP-seq
MIRT1197754	hsa-miR-4269	CLIP-seq
MIRT2583808	hsa-miR-4281	CLIP-seq
MIRT1197755	hsa-miR-4292	CLIP-seq
MIRT1197756	hsa-miR-4298	CLIP-seq
MIRT2057233	hsa-miR-4303	CLIP-seq
MIRT1197757	hsa-miR-4308	CLIP-seq
MIRT2686682	hsa-miR-4311	CLIP-seq
MIRT1197758	hsa-miR-4471	CLIP-seq
MIRT2583809	hsa-miR-4481	CLIP-seq
MIRT1197760	hsa-miR-4514	CLIP-seq
MIRT1197761	hsa-miR-4646-5p	CLIP-seq
MIRT1197762	hsa-miR-4648	CLIP-seq
MIRT2583810	hsa-miR-4651	CLIP-seq
MIRT1197763	hsa-miR-4654	CLIP-seq
MIRT2583811	hsa-miR-4664-5p	CLIP-seq
MIRT2285678	hsa-miR-4682	CLIP-seq
MIRT2583812	hsa-miR-4691-5p	CLIP-seq
MIRT1197766	hsa-miR-4692	CLIP-seq
MIRT1197768	hsa-miR-4742-5p	CLIP-seq
MIRT2583813	hsa-miR-4745-5p	CLIP-seq
MIRT2583814	hsa-miR-4758-5p	CLIP-seq
MIRT1197769	hsa-miR-4769-5p	CLIP-seq
MIRT1197771	hsa-miR-483-3p	CLIP-seq
MIRT2583815	hsa-miR-608	CLIP-seq
MIRT2583816	hsa-miR-933	CLIP-seq

Gene ontology (GO) Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 28241136, 32296183, 33961781, 35271311
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	28241136
GO:0005634	Component	Nucleus	IEA
GO:0006402	Process	MRNA catabolic process	IBA
GO:0016077	Process	Sno(s)RNA catabolic process	IBA
GO:0030515	Function	SnoRNA binding	IBA
GO:0030515	Function	SnoRNA binding	IDA	18820299, 21070968
GO:0042803	Function	Protein homodimerization activity	IDA	18820299
GO:0140933	Function	5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity	IDA	18820299, 21070968
GO:0140933	Function	5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity	ISS
GO:1990174	Function	Phosphodiesterase decapping endonuclease activity	IBA
GO:2001033	Process	Negative regulation of double-strand break repair via nonhomologous end joining	IDA	28241136

Other IDs

• MIM: 617338
• HGNC: 28154
• e!Ensembl: ENSG00000168101

Protein

• UniProt ID: Q9BRJ7
• Protein name: Tudor-interacting repair regulator protein (NUDT16-like protein 1) (Protein syndesmos)
• Protein function: Key regulator of TP53BP1 required to stabilize TP53BP1 and regulate its recruitment to chromatin (PubMed:28241136). In absence of DNA damage, interacts with the tandem Tudor-like domain of TP53BP1, masking the region that binds histone H4 dimeth
• PDB: 3KVH , 5ZCJ , 6CO1 , 6D0L , 8U3S
• Sequence:

  MSTAAVPELKQISRVEAMRLGPGWSHSCHAMLYAANPGQLFGRIPMRFSVLMQMRFDGLL
  GFPGGFVDRRFWSLEDGLNRVLGLGLGCLRLTEADYLSSHLTEGPHRVVAHLYARQLTLE
  QLHAVEISAVHSRDHGLEVLGLVRVPLYTQKDRVGGFPNFLSNAFVSTAKCQLLFALKVL
  NMMPEEKLVEALAAATEKQKKALEKLLPASS

• Sequence length: 211

Pathways

KEGG Pathway:

Proteoglycans in cancer

Related Genes

No strongly related genes found yet for NUDT16L1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to NUDT16L1.