Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	79716
Gene name	Aminopeptidase like 1
Gene symbol	NPEPL1
Synonyms (NCBI Gene)	bA261P9.2
Chromosome	20
Chromosome location	20q13.32

77 Show/Hide all (77)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017692	hsa-miR-335-5p	Microarray	18185580
MIRT019391	hsa-miR-148b-3p	Microarray	17612493
MIRT053790	hsa-miR-19a-3p	Luciferase reporter assayqRT-PCRWestern blot	22952885
MIRT1190567	hsa-let-7a	CLIP-seq
MIRT1190568	hsa-let-7b	CLIP-seq
MIRT1190569	hsa-let-7c	CLIP-seq
MIRT1190570	hsa-let-7d	CLIP-seq
MIRT1190571	hsa-let-7e	CLIP-seq
MIRT1190572	hsa-let-7f	CLIP-seq
MIRT1190573	hsa-let-7g	CLIP-seq
MIRT1190574	hsa-let-7i	CLIP-seq
MIRT1190575	hsa-miR-1294	CLIP-seq
MIRT1190576	hsa-miR-130a	CLIP-seq
MIRT1190577	hsa-miR-130b	CLIP-seq
MIRT1190578	hsa-miR-148a	CLIP-seq
MIRT1190579	hsa-miR-148b	CLIP-seq
MIRT1190580	hsa-miR-152	CLIP-seq
MIRT1190581	hsa-miR-1915	CLIP-seq
MIRT1190582	hsa-miR-19a	CLIP-seq
MIRT1190583	hsa-miR-19b	CLIP-seq
MIRT1190584	hsa-miR-202	CLIP-seq
MIRT1190585	hsa-miR-298	CLIP-seq
MIRT1190586	hsa-miR-301a	CLIP-seq
MIRT1190587	hsa-miR-301b	CLIP-seq
MIRT1190588	hsa-miR-342-5p	CLIP-seq
MIRT1190589	hsa-miR-3609	CLIP-seq
MIRT1190590	hsa-miR-3666	CLIP-seq
MIRT1190591	hsa-miR-4274	CLIP-seq
MIRT1190592	hsa-miR-4282	CLIP-seq
MIRT1190593	hsa-miR-4295	CLIP-seq
MIRT1190594	hsa-miR-4458	CLIP-seq
MIRT1190595	hsa-miR-4459	CLIP-seq
MIRT1190596	hsa-miR-4493	CLIP-seq
MIRT1190597	hsa-miR-4500	CLIP-seq
MIRT1190598	hsa-miR-4514	CLIP-seq
MIRT1190599	hsa-miR-4519	CLIP-seq
MIRT1190600	hsa-miR-4532	CLIP-seq
MIRT1190601	hsa-miR-454	CLIP-seq
MIRT1190602	hsa-miR-4664-5p	CLIP-seq
MIRT1190603	hsa-miR-4692	CLIP-seq
MIRT1190604	hsa-miR-4695-5p	CLIP-seq
MIRT1190605	hsa-miR-4720-3p	CLIP-seq
MIRT1190606	hsa-miR-4722-5p	CLIP-seq
MIRT1190607	hsa-miR-4804-3p	CLIP-seq
MIRT1190608	hsa-miR-518a-5p	CLIP-seq
MIRT1190609	hsa-miR-520g	CLIP-seq
MIRT1190610	hsa-miR-520h	CLIP-seq
MIRT1190611	hsa-miR-527	CLIP-seq
MIRT1190612	hsa-miR-548ah	CLIP-seq
MIRT1190613	hsa-miR-940	CLIP-seq
MIRT1190614	hsa-miR-98	CLIP-seq
MIRT2055184	hsa-miR-3135b	CLIP-seq
MIRT2055185	hsa-miR-3652	CLIP-seq
MIRT2055186	hsa-miR-4430	CLIP-seq
MIRT2055187	hsa-miR-4492	CLIP-seq
MIRT2055188	hsa-miR-4498	CLIP-seq
MIRT2055189	hsa-miR-4707-5p	CLIP-seq
MIRT2055190	hsa-miR-762	CLIP-seq
MIRT2055187	hsa-miR-4492	CLIP-seq
MIRT2055188	hsa-miR-4498	CLIP-seq
MIRT2284127	hsa-miR-548a-3p	CLIP-seq
MIRT2284128	hsa-miR-548e	CLIP-seq
MIRT2284129	hsa-miR-548f	CLIP-seq
MIRT2055190	hsa-miR-762	CLIP-seq
MIRT2055187	hsa-miR-4492	CLIP-seq
MIRT2055188	hsa-miR-4498	CLIP-seq
MIRT2055190	hsa-miR-762	CLIP-seq
MIRT1190581	hsa-miR-1915	CLIP-seq
MIRT1190585	hsa-miR-298	CLIP-seq
MIRT1190588	hsa-miR-342-5p	CLIP-seq
MIRT1190596	hsa-miR-4493	CLIP-seq
MIRT1190602	hsa-miR-4664-5p	CLIP-seq
MIRT1190581	hsa-miR-1915	CLIP-seq
MIRT1190585	hsa-miR-298	CLIP-seq
MIRT1190588	hsa-miR-342-5p	CLIP-seq
MIRT1190596	hsa-miR-4493	CLIP-seq
MIRT1190602	hsa-miR-4664-5p	CLIP-seq

13 Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004177	Function	Aminopeptidase activity	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0006508	Process	Proteolysis	IBA
GO:0006508	Process	Proteolysis	IEA
GO:0008233	Function	Peptidase activity	IBA
GO:0008233	Function	Peptidase activity	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0030145	Function	Manganese ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0070006	Function	Metalloaminopeptidase activity	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q8NDH3

Protein name

Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1)

Protein function

Probably catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00883	Peptidase_M17	179 → 484	Cytosol aminopeptidase family, catalytic domain	Domain
PF18295	Pdase_M17_N2	20 → 140	M17 aminopeptidase N-terminal domain 2	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:11853319}.

Sequence

MANVGLQFQASAGDSDPQSRPLLLLGQLHHLHRVPWSHVRGKLQPRVTEELWQAALSTLN
PNPTDSCPLYLNYATVAALPCRVSRHNSPSAAHFITRLVRTCLPPGAHRCIVMVCEQPEV
FASACALARAFPLFTHRSGASRRLEKKTVTVEFFLVGQDNGPVEVSTLQCLANATDGVRL
AARIVDTPCNEMNTDTFLEEINKVGKELGIIPTIIRDEELKTRGFGGIYGVGKAALHPPA
LAVLSHTPDGATQTIAWVGKGIVYDTGGLSIKGKTTMPGMKRDCGGAAAVLGAFRAAIKQ
GFKDNLHAVFCLAENSVGPNATRPDDIHLLYSGKTVEINNTDAEGRLVLADGVSYACKDL
GADIILDMATLTGAQGIATGKYHAAVLTNSAEWEAACVKAGRKCGDLVHPLVYCPELHFS
EFTSAVADMKNSVADRDNSPSSCAGLFIASHIGFDWPGVWVHLDIAAPVHAGERATGFGV
ALLLALFGRASEDPLLNLVSPLGCEVDVEEGDLGRDSKRRRLV

Sequence length

523

Interactions

View interactions

Related Genes Genes most often co-reported with NPEPL1 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for NPEPL1.

Diseases Linked via Similar Genes Diseases curated for genes most similar to NPEPL1 (see Related Genes above), that are NOT already directly curated for NPEPL1 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to NPEPL1.

NPEPL1 (aminopeptidase like 1)

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