NPDC1 (neural proliferation, differentiation and control 1)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 56654
• Gene name: Neural proliferation, differentiation and control 1
• Gene symbol: NPDC1
• Synonyms (NCBI Gene): CAB, CAB-, CAB-1, CAB1, NPDC-1
• Chromosome: 9
• Chromosome location: 9q34.3

miRNA Show/Hide all (33)

miRTarBase ID	miRNA	Experiments	Reference
MIRT044185	hsa-miR-99b-5p	CLASH	23622248
MIRT1190562	hsa-miR-1323	CLIP-seq
MIRT1190563	hsa-miR-1909	CLIP-seq
MIRT1190564	hsa-miR-3144-5p	CLIP-seq
MIRT1190565	hsa-miR-4768-3p	CLIP-seq
MIRT1190566	hsa-miR-548o	CLIP-seq
MIRT2055180	hsa-miR-1254	CLIP-seq
MIRT2055181	hsa-miR-2861	CLIP-seq
MIRT2055182	hsa-miR-3116	CLIP-seq
MIRT2055183	hsa-miR-4254	CLIP-seq
MIRT2055180	hsa-miR-1254	CLIP-seq
MIRT2055181	hsa-miR-2861	CLIP-seq
MIRT2055182	hsa-miR-3116	CLIP-seq
MIRT2055183	hsa-miR-4254	CLIP-seq
MIRT2055180	hsa-miR-1254	CLIP-seq
MIRT2582211	hsa-miR-1915	CLIP-seq
MIRT2055181	hsa-miR-2861	CLIP-seq
MIRT2582212	hsa-miR-31	CLIP-seq
MIRT2055182	hsa-miR-3116	CLIP-seq
MIRT2582213	hsa-miR-3128	CLIP-seq
MIRT2582214	hsa-miR-3918	CLIP-seq
MIRT2582215	hsa-miR-3936	CLIP-seq
MIRT2055183	hsa-miR-4254	CLIP-seq
MIRT2582216	hsa-miR-4287	CLIP-seq
MIRT2582217	hsa-miR-4292	CLIP-seq
MIRT2582218	hsa-miR-4308	CLIP-seq
MIRT2582219	hsa-miR-4469	CLIP-seq
MIRT2582220	hsa-miR-4512	CLIP-seq
MIRT2582221	hsa-miR-4685-3p	CLIP-seq
MIRT2582222	hsa-miR-4685-5p	CLIP-seq
MIRT2582223	hsa-miR-4726-3p	CLIP-seq
MIRT2582224	hsa-miR-4787-5p	CLIP-seq
MIRT2582225	hsa-miR-615-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 22396535, 25416956, 30388101, 32296183
GO:0005886	Component	Plasma membrane	TAS
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: 605798
• HGNC: 7899
• e!Ensembl: ENSG00000107281

Protein

• UniProt ID: Q9NQX5
• Protein name: Neural proliferation differentiation and control protein 1 (NPDC-1)
• Protein function: Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF06809	NPDC1	1 → 325	Neural proliferation differentiation control-1 protein (NPDC1)	Family

• Tissue specificity: TISSUE SPECIFICITY: Strongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe.
• Sequence:

  MATPLPPPSPRHLRLLRLLLSGLVLGAALRGAAAGHPDVAACPGSLDCALKRRARCPPGA
  HACGPCLQPFQEDQQGLCVPRMRRPPGGGRPQPRLEDEIDFLAQELARKESGHSTPPLPK
  DRQRLPEPATLGFSARGQGLELGLPSTPGTPTPTPHTSLGSPVSSDPVHMSPLEPRGGQG
  DGLALVLILAFCVAGAAALSVASLCWCRLQREIRLTQKADYATAKAPGSPAAPRISPGDQ
  RLAQSAEMYHYQHQRQQMLCLERHKEPPKELDTASSDEENEDGDFTVYECPGLAPTGEME
  VRNPLFDHAALSAPLPAPSSPPALP

• Sequence length: 325

Pathways

Reactome Pathway:

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Related Genes

No strongly related genes found yet for NPDC1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to NPDC1.