NOMO3 (NODAL modulator 3)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 408050
• Gene name: NODAL modulator 3
• Gene symbol: NOMO3
• Synonyms (NCBI Gene): Nomo
• Chromosome: 16
• Chromosome location: 16p13.11
• Summary: This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a duplicated region on the short arm of chromosome 16. These three genes encode closely related proteins that ma

miRNA Show/Hide all (267)

miRTarBase ID	miRNA	Experiments	Reference
MIRT051891	hsa-let-7b-5p	CLASH	23622248
MIRT045666	hsa-miR-149-5p	CLASH	23622248
MIRT044052	hsa-miR-362-5p	CLASH	23622248
MIRT041873	hsa-miR-484	CLASH	23622248
MIRT039922	hsa-miR-615-3p	CLASH	23622248
MIRT039026	hsa-miR-766-3p	CLASH	23622248
MIRT037055	hsa-miR-877-3p	CLASH	23622248
MIRT1189162	hsa-miR-1185	CLIP-seq
MIRT1189163	hsa-miR-128	CLIP-seq
MIRT1189164	hsa-miR-1286	CLIP-seq
MIRT1189165	hsa-miR-214	CLIP-seq
MIRT1189166	hsa-miR-2392	CLIP-seq
MIRT1189167	hsa-miR-25	CLIP-seq
MIRT1189168	hsa-miR-3064-3p	CLIP-seq
MIRT1189169	hsa-miR-3064-5p	CLIP-seq
MIRT1189170	hsa-miR-3180-5p	CLIP-seq
MIRT1189171	hsa-miR-3184	CLIP-seq
MIRT1189172	hsa-miR-32	CLIP-seq
MIRT1189173	hsa-miR-331-3p	CLIP-seq
MIRT1189174	hsa-miR-33a	CLIP-seq
MIRT1189175	hsa-miR-33b	CLIP-seq
MIRT1189176	hsa-miR-342-5p	CLIP-seq
MIRT1189177	hsa-miR-3605-5p	CLIP-seq
MIRT1189178	hsa-miR-3619-5p	CLIP-seq
MIRT1189179	hsa-miR-363	CLIP-seq
MIRT1189180	hsa-miR-367	CLIP-seq
MIRT1189181	hsa-miR-3672	CLIP-seq
MIRT1189182	hsa-miR-3677-5p	CLIP-seq
MIRT1189183	hsa-miR-3679-5p	CLIP-seq
MIRT1189184	hsa-miR-3681	CLIP-seq
MIRT1189185	hsa-miR-423-5p	CLIP-seq
MIRT1189186	hsa-miR-4283	CLIP-seq
MIRT1189187	hsa-miR-4291	CLIP-seq
MIRT1189188	hsa-miR-4317	CLIP-seq
MIRT1189189	hsa-miR-4459	CLIP-seq
MIRT1189190	hsa-miR-4466	CLIP-seq
MIRT1189191	hsa-miR-4475	CLIP-seq
MIRT1189192	hsa-miR-4504	CLIP-seq
MIRT1189193	hsa-miR-4651	CLIP-seq
MIRT1189194	hsa-miR-4664-5p	CLIP-seq
MIRT1189195	hsa-miR-4687-3p	CLIP-seq
MIRT1189196	hsa-miR-4710	CLIP-seq
MIRT1189197	hsa-miR-4722-5p	CLIP-seq
MIRT1189198	hsa-miR-4733-5p	CLIP-seq
MIRT1189199	hsa-miR-4743	CLIP-seq
MIRT1189200	hsa-miR-4767	CLIP-seq
MIRT1189201	hsa-miR-4779	CLIP-seq
MIRT1189202	hsa-miR-542-3p	CLIP-seq
MIRT1189203	hsa-miR-552	CLIP-seq
MIRT1189204	hsa-miR-608	CLIP-seq
MIRT1189205	hsa-miR-662	CLIP-seq
MIRT1189206	hsa-miR-663b	CLIP-seq
MIRT1189207	hsa-miR-664	CLIP-seq
MIRT1189208	hsa-miR-675	CLIP-seq
MIRT1189209	hsa-miR-759	CLIP-seq
MIRT1189210	hsa-miR-761	CLIP-seq
MIRT1189211	hsa-miR-922	CLIP-seq
MIRT1189212	hsa-miR-92a	CLIP-seq
MIRT1189213	hsa-miR-92b	CLIP-seq
MIRT1189162	hsa-miR-1185	CLIP-seq
MIRT2054770	hsa-miR-1245b-3p	CLIP-seq
MIRT1189165	hsa-miR-214	CLIP-seq
MIRT1189166	hsa-miR-2392	CLIP-seq
MIRT1189167	hsa-miR-25	CLIP-seq
MIRT1189170	hsa-miR-3180-5p	CLIP-seq
MIRT1189171	hsa-miR-3184	CLIP-seq
MIRT1189172	hsa-miR-32	CLIP-seq
MIRT2054771	hsa-miR-338-3p	CLIP-seq
MIRT1189174	hsa-miR-33a	CLIP-seq
MIRT1189175	hsa-miR-33b	CLIP-seq
MIRT2054772	hsa-miR-3591-3p	CLIP-seq
MIRT1189177	hsa-miR-3605-5p	CLIP-seq
MIRT1189178	hsa-miR-3619-5p	CLIP-seq
MIRT1189179	hsa-miR-363	CLIP-seq
MIRT1189180	hsa-miR-367	CLIP-seq
MIRT1189183	hsa-miR-3679-5p	CLIP-seq
MIRT1189185	hsa-miR-423-5p	CLIP-seq
MIRT2054773	hsa-miR-4258	CLIP-seq
MIRT1189186	hsa-miR-4283	CLIP-seq
MIRT1189188	hsa-miR-4317	CLIP-seq
MIRT2054774	hsa-miR-4330	CLIP-seq
MIRT2054775	hsa-miR-4530	CLIP-seq
MIRT1189196	hsa-miR-4710	CLIP-seq
MIRT2054776	hsa-miR-518a-5p	CLIP-seq
MIRT2054777	hsa-miR-527	CLIP-seq
MIRT1189207	hsa-miR-664	CLIP-seq
MIRT1189210	hsa-miR-761	CLIP-seq
MIRT1189212	hsa-miR-92a	CLIP-seq
MIRT1189213	hsa-miR-92b	CLIP-seq
MIRT1189162	hsa-miR-1185	CLIP-seq
MIRT1189164	hsa-miR-1286	CLIP-seq
MIRT1189166	hsa-miR-2392	CLIP-seq
MIRT1189167	hsa-miR-25	CLIP-seq
MIRT1189171	hsa-miR-3184	CLIP-seq
MIRT1189172	hsa-miR-32	CLIP-seq
MIRT1189174	hsa-miR-33a	CLIP-seq
MIRT1189175	hsa-miR-33b	CLIP-seq
MIRT1189177	hsa-miR-3605-5p	CLIP-seq
MIRT1189179	hsa-miR-363	CLIP-seq
MIRT1189180	hsa-miR-367	CLIP-seq
MIRT1189183	hsa-miR-3679-5p	CLIP-seq
MIRT2283853	hsa-miR-3682-5p	CLIP-seq
MIRT1189185	hsa-miR-423-5p	CLIP-seq
MIRT1189186	hsa-miR-4283	CLIP-seq
MIRT1189196	hsa-miR-4710	CLIP-seq
MIRT1189197	hsa-miR-4722-5p	CLIP-seq
MIRT2283854	hsa-miR-514	CLIP-seq
MIRT2283855	hsa-miR-514b-3p	CLIP-seq
MIRT1189212	hsa-miR-92a	CLIP-seq
MIRT1189213	hsa-miR-92b	CLIP-seq
MIRT2391649	hsa-miR-3646	CLIP-seq
MIRT2391650	hsa-miR-4719	CLIP-seq
MIRT2391651	hsa-miR-610	CLIP-seq
MIRT2439040	hsa-miR-15a	CLIP-seq
MIRT2439041	hsa-miR-15b	CLIP-seq
MIRT2439042	hsa-miR-16	CLIP-seq
MIRT2439043	hsa-miR-195	CLIP-seq
MIRT1189167	hsa-miR-25	CLIP-seq
MIRT1189171	hsa-miR-3184	CLIP-seq
MIRT1189172	hsa-miR-32	CLIP-seq
MIRT1189174	hsa-miR-33a	CLIP-seq
MIRT1189175	hsa-miR-33b	CLIP-seq
MIRT1189176	hsa-miR-342-5p	CLIP-seq
MIRT1189179	hsa-miR-363	CLIP-seq
MIRT1189180	hsa-miR-367	CLIP-seq
MIRT1189185	hsa-miR-423-5p	CLIP-seq
MIRT2439044	hsa-miR-424	CLIP-seq
MIRT1189186	hsa-miR-4283	CLIP-seq
MIRT1189188	hsa-miR-4317	CLIP-seq
MIRT2439045	hsa-miR-4438	CLIP-seq
MIRT1189189	hsa-miR-4459	CLIP-seq
MIRT1189190	hsa-miR-4466	CLIP-seq
MIRT1189191	hsa-miR-4475	CLIP-seq
MIRT2054775	hsa-miR-4530	CLIP-seq
MIRT1189193	hsa-miR-4651	CLIP-seq
MIRT1189194	hsa-miR-4664-5p	CLIP-seq
MIRT1189200	hsa-miR-4767	CLIP-seq
MIRT1189201	hsa-miR-4779	CLIP-seq
MIRT2439046	hsa-miR-497	CLIP-seq
MIRT1189204	hsa-miR-608	CLIP-seq
MIRT1189207	hsa-miR-664	CLIP-seq
MIRT1189208	hsa-miR-675	CLIP-seq
MIRT1189212	hsa-miR-92a	CLIP-seq
MIRT1189213	hsa-miR-92b	CLIP-seq
MIRT1189167	hsa-miR-25	CLIP-seq
MIRT1189172	hsa-miR-32	CLIP-seq
MIRT1189174	hsa-miR-33a	CLIP-seq
MIRT1189175	hsa-miR-33b	CLIP-seq
MIRT1189179	hsa-miR-363	CLIP-seq
MIRT1189180	hsa-miR-367	CLIP-seq
MIRT1189188	hsa-miR-4317	CLIP-seq
MIRT1189189	hsa-miR-4459	CLIP-seq
MIRT1189201	hsa-miR-4779	CLIP-seq
MIRT1189207	hsa-miR-664	CLIP-seq
MIRT1189212	hsa-miR-92a	CLIP-seq
MIRT1189213	hsa-miR-92b	CLIP-seq
MIRT1189162	hsa-miR-1185	CLIP-seq
MIRT2582005	hsa-miR-1228	CLIP-seq
MIRT1189163	hsa-miR-128	CLIP-seq
MIRT1189164	hsa-miR-1286	CLIP-seq
MIRT2582006	hsa-miR-140-3p	CLIP-seq
MIRT2439040	hsa-miR-15a	CLIP-seq
MIRT2439041	hsa-miR-15b	CLIP-seq
MIRT2439042	hsa-miR-16	CLIP-seq
MIRT2439043	hsa-miR-195	CLIP-seq
MIRT1189166	hsa-miR-2392	CLIP-seq
MIRT1189167	hsa-miR-25	CLIP-seq
MIRT1189168	hsa-miR-3064-3p	CLIP-seq
MIRT1189171	hsa-miR-3184	CLIP-seq
MIRT1189172	hsa-miR-32	CLIP-seq
MIRT1189174	hsa-miR-33a	CLIP-seq
MIRT1189175	hsa-miR-33b	CLIP-seq
MIRT1189176	hsa-miR-342-5p	CLIP-seq
MIRT1189177	hsa-miR-3605-5p	CLIP-seq
MIRT1189179	hsa-miR-363	CLIP-seq
MIRT1189180	hsa-miR-367	CLIP-seq
MIRT1189183	hsa-miR-3679-5p	CLIP-seq
MIRT2283853	hsa-miR-3682-5p	CLIP-seq
MIRT2582007	hsa-miR-3929	CLIP-seq
MIRT1189185	hsa-miR-423-5p	CLIP-seq
MIRT2439044	hsa-miR-424	CLIP-seq
MIRT1189186	hsa-miR-4283	CLIP-seq
MIRT1189187	hsa-miR-4291	CLIP-seq
MIRT1189188	hsa-miR-4317	CLIP-seq
MIRT2582008	hsa-miR-4419b	CLIP-seq
MIRT2439045	hsa-miR-4438	CLIP-seq
MIRT1189189	hsa-miR-4459	CLIP-seq
MIRT1189190	hsa-miR-4466	CLIP-seq
MIRT1189191	hsa-miR-4475	CLIP-seq
MIRT2582009	hsa-miR-4478	CLIP-seq
MIRT1189192	hsa-miR-4504	CLIP-seq
MIRT2054775	hsa-miR-4530	CLIP-seq
MIRT1189193	hsa-miR-4651	CLIP-seq
MIRT2582010	hsa-miR-4652-3p	CLIP-seq
MIRT1189194	hsa-miR-4664-5p	CLIP-seq
MIRT2582011	hsa-miR-4670-3p	CLIP-seq
MIRT1189196	hsa-miR-4710	CLIP-seq
MIRT1189197	hsa-miR-4722-5p	CLIP-seq
MIRT1189200	hsa-miR-4767	CLIP-seq
MIRT2582012	hsa-miR-4778-5p	CLIP-seq
MIRT1189201	hsa-miR-4779	CLIP-seq
MIRT2439046	hsa-miR-497	CLIP-seq
MIRT2283854	hsa-miR-514	CLIP-seq
MIRT2283855	hsa-miR-514b-3p	CLIP-seq
MIRT1189204	hsa-miR-608	CLIP-seq
MIRT1189207	hsa-miR-664	CLIP-seq
MIRT1189208	hsa-miR-675	CLIP-seq
MIRT1189212	hsa-miR-92a	CLIP-seq
MIRT1189213	hsa-miR-92b	CLIP-seq
MIRT1189162	hsa-miR-1185	CLIP-seq
MIRT2582005	hsa-miR-1228	CLIP-seq
MIRT1189163	hsa-miR-128	CLIP-seq
MIRT1189164	hsa-miR-1286	CLIP-seq
MIRT2582006	hsa-miR-140-3p	CLIP-seq
MIRT2439040	hsa-miR-15a	CLIP-seq
MIRT2439041	hsa-miR-15b	CLIP-seq
MIRT2439042	hsa-miR-16	CLIP-seq
MIRT2439043	hsa-miR-195	CLIP-seq
MIRT1189165	hsa-miR-214	CLIP-seq
MIRT1189166	hsa-miR-2392	CLIP-seq
MIRT1189167	hsa-miR-25	CLIP-seq
MIRT1189168	hsa-miR-3064-3p	CLIP-seq
MIRT1189171	hsa-miR-3184	CLIP-seq
MIRT1189172	hsa-miR-32	CLIP-seq
MIRT1189174	hsa-miR-33a	CLIP-seq
MIRT1189175	hsa-miR-33b	CLIP-seq
MIRT1189176	hsa-miR-342-5p	CLIP-seq
MIRT2054772	hsa-miR-3591-3p	CLIP-seq
MIRT1189177	hsa-miR-3605-5p	CLIP-seq
MIRT1189178	hsa-miR-3619-5p	CLIP-seq
MIRT1189179	hsa-miR-363	CLIP-seq
MIRT1189180	hsa-miR-367	CLIP-seq
MIRT1189183	hsa-miR-3679-5p	CLIP-seq
MIRT2283853	hsa-miR-3682-5p	CLIP-seq
MIRT2582007	hsa-miR-3929	CLIP-seq
MIRT1189185	hsa-miR-423-5p	CLIP-seq
MIRT2439044	hsa-miR-424	CLIP-seq
MIRT1189186	hsa-miR-4283	CLIP-seq
MIRT1189187	hsa-miR-4291	CLIP-seq
MIRT1189188	hsa-miR-4317	CLIP-seq
MIRT2582008	hsa-miR-4419b	CLIP-seq
MIRT2439045	hsa-miR-4438	CLIP-seq
MIRT1189189	hsa-miR-4459	CLIP-seq
MIRT1189190	hsa-miR-4466	CLIP-seq
MIRT1189191	hsa-miR-4475	CLIP-seq
MIRT2582009	hsa-miR-4478	CLIP-seq
MIRT1189192	hsa-miR-4504	CLIP-seq
MIRT2054775	hsa-miR-4530	CLIP-seq
MIRT1189193	hsa-miR-4651	CLIP-seq
MIRT2582010	hsa-miR-4652-3p	CLIP-seq
MIRT1189194	hsa-miR-4664-5p	CLIP-seq
MIRT2582011	hsa-miR-4670-3p	CLIP-seq
MIRT1189196	hsa-miR-4710	CLIP-seq
MIRT1189197	hsa-miR-4722-5p	CLIP-seq
MIRT1189200	hsa-miR-4767	CLIP-seq
MIRT2582012	hsa-miR-4778-5p	CLIP-seq
MIRT1189201	hsa-miR-4779	CLIP-seq
MIRT2439046	hsa-miR-497	CLIP-seq
MIRT2283854	hsa-miR-514	CLIP-seq
MIRT2283855	hsa-miR-514b-3p	CLIP-seq
MIRT1189204	hsa-miR-608	CLIP-seq
MIRT1189207	hsa-miR-664	CLIP-seq
MIRT1189208	hsa-miR-675	CLIP-seq
MIRT1189210	hsa-miR-761	CLIP-seq
MIRT1189211	hsa-miR-922	CLIP-seq
MIRT1189212	hsa-miR-92a	CLIP-seq
MIRT1189213	hsa-miR-92b	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003140	Process	Determination of left/right asymmetry in lateral mesoderm	ISS
GO:0005515	Function	Protein binding	IPI	22046132, 32820719, 33961781
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0030246	Function	Carbohydrate binding	IEA
GO:0043022	Function	Ribosome binding	IDA	32820719
GO:0043022	Function	Ribosome binding	IEA
GO:0160063	Process	Multi-pass transmembrane protein insertion into ER membrane	IDA	36261522
GO:0160063	Process	Multi-pass transmembrane protein insertion into ER membrane	IEA
GO:0160064	Component	Multi-pass translocon complex	IDA	36261522
GO:0160064	Component	Multi-pass translocon complex	IEA
GO:1900108	Process	Negative regulation of nodal signaling pathway	ISS

Other IDs

• MIM: 609159
• HGNC: 25242
• e!Ensembl: ENSG00000103226

Protein

• UniProt ID: P69849
• Protein name: BOS complex subunit NOMO3 (Nodal modulator 3) (pM5 protein 3)
• Protein function: Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:32820719, PubMed:36261522). The MPT complex takes over after the SEC61 complex: following me
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13620	CarboxypepD_reg	330 → 406		Domain
  PF17802	SpaA	871 → 928	Prealbumin-like fold domain	Domain

• Sequence:

  MLVGQGAGPLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
  KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
  DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
  YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
  LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
  TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
  ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGQISIIRFP
  DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKANPGTYKVQVMVPEAETRAGLTLK
  PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
  NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
  TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
  LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
  REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
  AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
  GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
  LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
  YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
  EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
  ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
  ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
  ASDNSGPEDAKRQAKKQKTRRT

• Sequence length: 1222

Related Genes

No strongly related genes found yet for NOMO3.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to NOMO3.