NGDN (neuroguidin)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 25983
• Gene name: Neuroguidin
• Gene symbol: NGDN
• Synonyms (NCBI Gene): C14orf120, CANu1, LCP5, NGD, lpd-2
• Chromosome: 14
• Chromosome location: 14q11.2
• Summary: Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar

miRNA Show/Hide all (138)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022245	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT721448	hsa-miR-495-3p	HITS-CLIP	19536157
MIRT721446	hsa-miR-5688	HITS-CLIP	19536157
MIRT721447	hsa-miR-7-1-3p	HITS-CLIP	19536157
MIRT721445	hsa-miR-7-2-3p	HITS-CLIP	19536157
MIRT721444	hsa-miR-154-3p	HITS-CLIP	19536157
MIRT721443	hsa-miR-487a-3p	HITS-CLIP	19536157
MIRT721442	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT721441	hsa-miR-496	HITS-CLIP	19536157
MIRT721440	hsa-miR-485-3p	HITS-CLIP	19536157
MIRT721439	hsa-miR-539-3p	HITS-CLIP	19536157
MIRT630966	hsa-miR-4267	HITS-CLIP	23824327
MIRT630965	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT630964	hsa-miR-1202	HITS-CLIP	23824327
MIRT630963	hsa-miR-3972	HITS-CLIP	23824327
MIRT630962	hsa-miR-5006-5p	HITS-CLIP	23824327
MIRT630961	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT630960	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT630966	hsa-miR-4267	HITS-CLIP	23824327
MIRT630965	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT630964	hsa-miR-1202	HITS-CLIP	23824327
MIRT630963	hsa-miR-3972	HITS-CLIP	23824327
MIRT630962	hsa-miR-5006-5p	HITS-CLIP	23824327
MIRT630961	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT630960	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT655848	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT655846	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT655847	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT655845	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT655844	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT655843	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT655842	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT655841	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT655840	hsa-miR-623	HITS-CLIP	23824327
MIRT655839	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT655837	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT655838	hsa-miR-5096	HITS-CLIP	23824327
MIRT655836	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT655848	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT655846	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT655847	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT655845	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT655844	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT655843	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT655842	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT655841	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT655840	hsa-miR-623	HITS-CLIP	23824327
MIRT655839	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT655837	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT655838	hsa-miR-5096	HITS-CLIP	23824327
MIRT655836	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT630966	hsa-miR-4267	HITS-CLIP	23824327
MIRT630965	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT630964	hsa-miR-1202	HITS-CLIP	23824327
MIRT630963	hsa-miR-3972	HITS-CLIP	23824327
MIRT630962	hsa-miR-5006-5p	HITS-CLIP	23824327
MIRT630961	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT630960	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT721448	hsa-miR-495-3p	HITS-CLIP	19536157
MIRT721446	hsa-miR-5688	HITS-CLIP	19536157
MIRT721447	hsa-miR-7-1-3p	HITS-CLIP	19536157
MIRT721445	hsa-miR-7-2-3p	HITS-CLIP	19536157
MIRT721444	hsa-miR-154-3p	HITS-CLIP	19536157
MIRT721443	hsa-miR-487a-3p	HITS-CLIP	19536157
MIRT721442	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT721441	hsa-miR-496	HITS-CLIP	19536157
MIRT721440	hsa-miR-485-3p	HITS-CLIP	19536157
MIRT721439	hsa-miR-539-3p	HITS-CLIP	19536157
MIRT630966	hsa-miR-4267	HITS-CLIP	23824327
MIRT630965	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT630964	hsa-miR-1202	HITS-CLIP	23824327
MIRT630963	hsa-miR-3972	HITS-CLIP	23824327
MIRT630962	hsa-miR-5006-5p	HITS-CLIP	23824327
MIRT630961	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT630960	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT630966	hsa-miR-4267	HITS-CLIP	23824327
MIRT630965	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT630964	hsa-miR-1202	HITS-CLIP	23824327
MIRT630963	hsa-miR-3972	HITS-CLIP	23824327
MIRT630962	hsa-miR-5006-5p	HITS-CLIP	23824327
MIRT630961	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT630960	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT655848	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT655846	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT655847	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT655845	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT655844	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT655843	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT655842	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT655841	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT655840	hsa-miR-623	HITS-CLIP	23824327
MIRT655839	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT655837	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT655838	hsa-miR-5096	HITS-CLIP	23824327
MIRT655836	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT655848	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT655846	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT655847	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT655845	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT655844	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT655843	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT655842	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT655841	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT655840	hsa-miR-623	HITS-CLIP	23824327
MIRT655839	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT655837	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT655838	hsa-miR-5096	HITS-CLIP	23824327
MIRT655836	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT630966	hsa-miR-4267	HITS-CLIP	23824327
MIRT630965	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT630964	hsa-miR-1202	HITS-CLIP	23824327
MIRT630963	hsa-miR-3972	HITS-CLIP	23824327
MIRT630962	hsa-miR-5006-5p	HITS-CLIP	23824327
MIRT630961	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT630960	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT1184109	hsa-miR-330-3p	CLIP-seq
MIRT1184110	hsa-miR-4452	CLIP-seq
MIRT1184111	hsa-miR-4668-5p	CLIP-seq
MIRT1184112	hsa-miR-4685-5p	CLIP-seq
MIRT1184113	hsa-miR-548aa	CLIP-seq
MIRT1184114	hsa-miR-1912	CLIP-seq
MIRT1184115	hsa-miR-300	CLIP-seq
MIRT1184109	hsa-miR-330-3p	CLIP-seq
MIRT1184116	hsa-miR-381	CLIP-seq
MIRT1184117	hsa-miR-4311	CLIP-seq
MIRT1184110	hsa-miR-4452	CLIP-seq
MIRT1184118	hsa-miR-4470	CLIP-seq
MIRT1184119	hsa-miR-4666-3p	CLIP-seq
MIRT1184111	hsa-miR-4668-5p	CLIP-seq
MIRT1184112	hsa-miR-4685-5p	CLIP-seq
MIRT1184113	hsa-miR-548aa	CLIP-seq
MIRT2282602	hsa-miR-3124-3p	CLIP-seq
MIRT1184109	hsa-miR-330-3p	CLIP-seq
MIRT2282603	hsa-miR-3692	CLIP-seq
MIRT1184110	hsa-miR-4452	CLIP-seq
MIRT1184111	hsa-miR-4668-5p	CLIP-seq
MIRT1184112	hsa-miR-4685-5p	CLIP-seq
MIRT1184113	hsa-miR-548aa	CLIP-seq

Gene ontology (GO) Show/Hide all (20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000462	Process	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA
GO:0000775	Component	Chromosome, centromeric region	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	25416956, 30021884, 30177828, 32296183, 33961781, 35271311
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005694	Component	Chromosome	IEA
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IDA
GO:0006417	Process	Regulation of translation	IEA
GO:0030175	Component	Filopodium	IEA
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	IEA
GO:0032040	Component	Small-subunit processome	IBA
GO:0032040	Component	Small-subunit processome	IDA	34516797
GO:0042274	Process	Ribosomal small subunit biogenesis	IDA	34516797
GO:0042995	Component	Cell projection	IEA

Other IDs

• MIM: 610777
• HGNC: 20271
• e!Ensembl: ENSG00000129460

Protein

• UniProt ID: Q8NEJ9
• Protein name: Neuroguidin (Centromere accumulated nuclear protein 1) (CANu1) (EIF4E-binding protein)
• Protein function: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associat
• PDB: 7MQ8
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04000	Sas10_Utp3	18 → 98	Sas10/Utp3/C1D family	Family

• Sequence:

  MAALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLL
  LMYLMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTG
  SLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVH
  YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRIN
  YEESMMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKK
  IPQKGRKKKGFRRRR

• Sequence length: 315

Related Genes

No strongly related genes found yet for NGDN.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to NGDN.