NEAT1 (nuclear paraspeckle assembly transcript 1) | Gene Details, Disease Associations & Pathways | GeDiPNet

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Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	283131
Gene name	Nuclear paraspeckle assembly transcript 1
Gene symbol	NEAT1
Synonyms (NCBI Gene)	LINC00084NCRNA00084TP53LC15TncRNAVINC
Chromosome	11
Chromosome location	11q13.1
Summary	This gene produces a long non-coding RNA (lncRNA) transcribed from the multiple endocrine neoplasia locus. This lncRNA is retained in the nucleus where it forms the core structural component of the paraspeckle sub-organelles. It may act as a transcription

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miRTarBase ID	miRNA	Experiments	Reference
MIRT731903	hsa-miR-124-3p	Luciferase reporter assay	27075229
MIRT731903	hsa-miR-124-3p	Luciferase reporter assay	27075229
MIRT731903	hsa-miR-124-3p	Luciferase reporter assay	27075229
MIRT732655	hsa-miR-205-5p	Immunoprecipitaion (IP)Luciferase reporter assayqRT-PCRWestern blotting	34101306
MIRT732796	hsa-miR-143-3p	qRT-PCR	33744906
MIRT732655	hsa-miR-205-5p	Immunoprecipitaion (IP)Luciferase reporter assayqRT-PCRWestern blotting	32065361
MIRT735010	hsa-miR-373-3p	Luciferase reporter assayqRT-PCRIn situ hybridizationFlow cytometry	33093438
MIRT735018	hsa-miR-22-3p	Luciferase reporter assayWestern blottingqRT-PCR	32826883
MIRT737191	hsa-miR-21-3p	RNA-seqqRT-PCR	31621912
MIRT756095	hsa-miR-338-3p	Luciferase reporter assayWestern blottingqRT-PCRImmunoprecipitaion (IP)Immunofluorescence	38472205
MIRT756237	hsa-miR-1-3p	Luciferase reporter assay	34787068
MIRT756239	hsa-miR-26a-5p	Luciferase reporter assayqRT-PCR	34804856
MIRT756281	hsa-miR-493-5p	Luciferase reporter assayNorthern blotting	37249278

1

Transcription factor	Regulation	Reference
SFPQ	Unknown	24507715

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000512	Process	LncRNA-mediated post-transcriptional gene silencing	IDA	28379604
GO:0006325	Process	Chromatin organization	IEA
GO:0010793	Process	Regulation of mRNA export from nucleus	IMP	19716791
GO:0016442	Component	RISC complex	IEA
GO:0030575	Process	Nuclear body organization	IMP	19716791
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035198	Function	MiRNA binding	IDA	28379604
GO:0042382	Component	Paraspeckles	IDA	19716791
GO:0042382	Component	Paraspeckles	IEA
GO:0042382	Component	Paraspeckles	TAS	31048766
GO:0050729	Process	Positive regulation of inflammatory response	IMP	28379604
GO:0140463	Function	Chromatin-protein adaptor activity	IDA	25155612
GO:0140693	Function	Molecular condensate scaffold activity	IMP	19716791
GO:0140693	Function	Molecular condensate scaffold activity	TAS	31048766
GO:0140869	Function	MiRNA inhibitor activity via base-pairing	IDA	28379604
GO:1901647	Process	Positive regulation of synoviocyte proliferation	IMP	28379604
GO:1905172	Function	RISC complex binding	IDA	28379604
GO:2000627	Process	Positive regulation of miRNA catabolic process	IMP	28379604

MIM	HGNC	e!Ensembl
612769	30815	ENSG00000245532

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