Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	4711
Gene name	NADH:ubiquinone oxidoreductase subunit B5
Gene symbol	NDUFB5
Synonyms (NCBI Gene)	CISGDHSGDH
Chromosome	3
Chromosome location	3q26.33
Summary	The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase act

231 Show/Hide all (231)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016164	hsa-miR-590-3p	Sequencing	20371350
MIRT024139	hsa-miR-221-3p	Sequencing	20371350
MIRT028994	hsa-miR-26b-5p	Microarray	19088304
MIRT643108	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT643107	hsa-miR-3607-5p	HITS-CLIP	23824327
MIRT643106	hsa-miR-3183	HITS-CLIP	23824327
MIRT643105	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT643104	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT643103	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT643102	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT643101	hsa-miR-3688-5p	HITS-CLIP	23824327
MIRT643100	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT643099	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT643098	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT643097	hsa-miR-4279	HITS-CLIP	23824327
MIRT643096	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT643095	hsa-miR-5590-5p	HITS-CLIP	23824327
MIRT643094	hsa-miR-4659a-5p	HITS-CLIP	23824327
MIRT643093	hsa-miR-4659b-5p	HITS-CLIP	23824327
MIRT643092	hsa-miR-5691	HITS-CLIP	23824327
MIRT643091	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT643090	hsa-miR-4642	HITS-CLIP	23824327
MIRT643089	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT617591	hsa-miR-4432	HITS-CLIP	23824327
MIRT617590	hsa-miR-3120-3p	HITS-CLIP	23824327
MIRT617589	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617588	hsa-miR-451b	HITS-CLIP	23824327
MIRT617587	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT617586	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT617585	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT617584	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT617583	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT617582	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT617581	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT617580	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT617579	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617578	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT617577	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT617576	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT617575	hsa-miR-4696	HITS-CLIP	23824327
MIRT617574	hsa-miR-661	HITS-CLIP	23824327
MIRT617573	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT617572	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT617571	hsa-miR-7703	HITS-CLIP	23824327
MIRT617570	hsa-miR-1262	HITS-CLIP	23824327
MIRT617569	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT617568	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT549930	hsa-miR-6512-5p	PAR-CLIP	21572407
MIRT549931	hsa-miR-504-5p	PAR-CLIP	21572407
MIRT549929	hsa-miR-10a-5p	PAR-CLIP	21572407
MIRT549928	hsa-miR-10b-5p	PAR-CLIP	21572407
MIRT549926	hsa-miR-6074	PAR-CLIP	21572407
MIRT549927	hsa-miR-4272	PAR-CLIP	21572407
MIRT549925	hsa-miR-4528	PAR-CLIP	21572407
MIRT549924	hsa-miR-29a-5p	PAR-CLIP	21572407
MIRT549923	hsa-miR-591	PAR-CLIP	21572407
MIRT549922	hsa-miR-3671	PAR-CLIP	21572407
MIRT549921	hsa-miR-607	PAR-CLIP	21572407
MIRT486396	hsa-miR-543	PAR-CLIP	23592263
MIRT486395	hsa-miR-3688-3p	PAR-CLIP	23592263
MIRT377479	hsa-miR-571	PAR-CLIP	23592263
MIRT486394	hsa-miR-3143	PAR-CLIP	23592263
MIRT486393	hsa-miR-218-1-3p	PAR-CLIP	23592263
MIRT486392	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT377481	hsa-miR-1303	PAR-CLIP	23592263
MIRT377480	hsa-miR-659-3p	PAR-CLIP	23592263
MIRT643108	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT643107	hsa-miR-3607-5p	HITS-CLIP	23824327
MIRT643106	hsa-miR-3183	HITS-CLIP	23824327
MIRT643105	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT643104	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT643103	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT643102	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT643101	hsa-miR-3688-5p	HITS-CLIP	23824327
MIRT643100	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT643099	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT643098	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT643097	hsa-miR-4279	HITS-CLIP	23824327
MIRT643096	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT643095	hsa-miR-5590-5p	HITS-CLIP	23824327
MIRT643094	hsa-miR-4659a-5p	HITS-CLIP	23824327
MIRT643093	hsa-miR-4659b-5p	HITS-CLIP	23824327
MIRT643092	hsa-miR-5691	HITS-CLIP	23824327
MIRT643091	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT643090	hsa-miR-4642	HITS-CLIP	23824327
MIRT643089	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT617591	hsa-miR-4432	HITS-CLIP	23824327
MIRT617590	hsa-miR-3120-3p	HITS-CLIP	23824327
MIRT617589	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT617588	hsa-miR-451b	HITS-CLIP	23824327
MIRT617587	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT617586	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT617585	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT617584	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT617583	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT617582	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT617581	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT617580	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT617579	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT617578	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT617577	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT617576	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT617575	hsa-miR-4696	HITS-CLIP	23824327
MIRT617574	hsa-miR-661	HITS-CLIP	23824327
MIRT617573	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT617572	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT617571	hsa-miR-7703	HITS-CLIP	23824327
MIRT617570	hsa-miR-1262	HITS-CLIP	23824327
MIRT617569	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT617568	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT549930	hsa-miR-6512-5p	PAR-CLIP	21572407
MIRT549931	hsa-miR-504-5p	PAR-CLIP	21572407
MIRT549929	hsa-miR-10a-5p	PAR-CLIP	21572407
MIRT549928	hsa-miR-10b-5p	PAR-CLIP	21572407
MIRT549926	hsa-miR-6074	PAR-CLIP	21572407
MIRT549927	hsa-miR-4272	PAR-CLIP	21572407
MIRT549925	hsa-miR-4528	PAR-CLIP	21572407
MIRT549924	hsa-miR-29a-5p	PAR-CLIP	21572407
MIRT549923	hsa-miR-591	PAR-CLIP	21572407
MIRT549922	hsa-miR-3671	PAR-CLIP	21572407
MIRT549921	hsa-miR-607	PAR-CLIP	21572407
MIRT486396	hsa-miR-543	PAR-CLIP	23592263
MIRT486395	hsa-miR-3688-3p	PAR-CLIP	23592263
MIRT377479	hsa-miR-571	PAR-CLIP	23592263
MIRT486394	hsa-miR-3143	PAR-CLIP	23592263
MIRT486393	hsa-miR-218-1-3p	PAR-CLIP	23592263
MIRT486392	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT377481	hsa-miR-1303	PAR-CLIP	23592263
MIRT377480	hsa-miR-659-3p	PAR-CLIP	23592263
MIRT1179001	hsa-miR-101	CLIP-seq
MIRT1179002	hsa-miR-139-5p	CLIP-seq
MIRT1179003	hsa-miR-144	CLIP-seq
MIRT1179004	hsa-miR-151-3p	CLIP-seq
MIRT1179005	hsa-miR-2467-5p	CLIP-seq
MIRT1179006	hsa-miR-3173-3p	CLIP-seq
MIRT1179007	hsa-miR-337-3p	CLIP-seq
MIRT1179008	hsa-miR-369-3p	CLIP-seq
MIRT1179009	hsa-miR-374c	CLIP-seq
MIRT1179010	hsa-miR-3907	CLIP-seq
MIRT1179011	hsa-miR-4257	CLIP-seq
MIRT1179012	hsa-miR-4266	CLIP-seq
MIRT1179013	hsa-miR-4424	CLIP-seq
MIRT1179014	hsa-miR-4428	CLIP-seq
MIRT1179015	hsa-miR-4438	CLIP-seq
MIRT1179016	hsa-miR-4477a	CLIP-seq
MIRT1179017	hsa-miR-4477b	CLIP-seq
MIRT1179018	hsa-miR-4645-3p	CLIP-seq
MIRT1179019	hsa-miR-4653-3p	CLIP-seq
MIRT1179020	hsa-miR-4668-3p	CLIP-seq
MIRT1179021	hsa-miR-4719	CLIP-seq
MIRT1179022	hsa-miR-4720-3p	CLIP-seq
MIRT1179023	hsa-miR-4775	CLIP-seq
MIRT1179024	hsa-miR-4804-3p	CLIP-seq
MIRT1179025	hsa-miR-5095	CLIP-seq
MIRT1179026	hsa-miR-5096	CLIP-seq
MIRT1179027	hsa-miR-513b	CLIP-seq
MIRT1179028	hsa-miR-548p	CLIP-seq
MIRT1179029	hsa-miR-548q	CLIP-seq
MIRT1179030	hsa-miR-580	CLIP-seq
MIRT1179031	hsa-miR-651	CLIP-seq
MIRT1179032	hsa-miR-655	CLIP-seq
MIRT1179033	hsa-miR-659	CLIP-seq
MIRT1179001	hsa-miR-101	CLIP-seq
MIRT1179002	hsa-miR-139-5p	CLIP-seq
MIRT1179003	hsa-miR-144	CLIP-seq
MIRT1179004	hsa-miR-151-3p	CLIP-seq
MIRT1179008	hsa-miR-369-3p	CLIP-seq
MIRT1179009	hsa-miR-374c	CLIP-seq
MIRT1179015	hsa-miR-4438	CLIP-seq
MIRT1179025	hsa-miR-5095	CLIP-seq
MIRT1179032	hsa-miR-655	CLIP-seq
MIRT1179001	hsa-miR-101	CLIP-seq
MIRT2579324	hsa-miR-1200	CLIP-seq
MIRT1179002	hsa-miR-139-5p	CLIP-seq
MIRT1179003	hsa-miR-144	CLIP-seq
MIRT1179004	hsa-miR-151-3p	CLIP-seq
MIRT1179006	hsa-miR-3173-3p	CLIP-seq
MIRT1179010	hsa-miR-3907	CLIP-seq
MIRT2579325	hsa-miR-4324	CLIP-seq
MIRT1179013	hsa-miR-4424	CLIP-seq
MIRT1179014	hsa-miR-4428	CLIP-seq
MIRT1179015	hsa-miR-4438	CLIP-seq
MIRT1179016	hsa-miR-4477a	CLIP-seq
MIRT1179017	hsa-miR-4477b	CLIP-seq
MIRT1179019	hsa-miR-4653-3p	CLIP-seq
MIRT1179020	hsa-miR-4668-3p	CLIP-seq
MIRT2579326	hsa-miR-4682	CLIP-seq
MIRT1179022	hsa-miR-4720-3p	CLIP-seq
MIRT1179024	hsa-miR-4804-3p	CLIP-seq
MIRT1179025	hsa-miR-5095	CLIP-seq
MIRT2579327	hsa-miR-544b	CLIP-seq
MIRT1179029	hsa-miR-548q	CLIP-seq
MIRT1179030	hsa-miR-580	CLIP-seq
MIRT1179033	hsa-miR-659	CLIP-seq
MIRT1179001	hsa-miR-101	CLIP-seq
MIRT2579324	hsa-miR-1200	CLIP-seq
MIRT2686086	hsa-miR-1248	CLIP-seq
MIRT1179002	hsa-miR-139-5p	CLIP-seq
MIRT1179003	hsa-miR-144	CLIP-seq
MIRT1179004	hsa-miR-151-3p	CLIP-seq
MIRT2686087	hsa-miR-2110	CLIP-seq
MIRT2686088	hsa-miR-219-1-3p	CLIP-seq
MIRT2686089	hsa-miR-3144-5p	CLIP-seq
MIRT2686090	hsa-miR-3150a-3p	CLIP-seq
MIRT1179006	hsa-miR-3173-3p	CLIP-seq
MIRT2686091	hsa-miR-3191	CLIP-seq
MIRT2686092	hsa-miR-3199	CLIP-seq
MIRT1179010	hsa-miR-3907	CLIP-seq
MIRT2686093	hsa-miR-4260	CLIP-seq
MIRT2579325	hsa-miR-4324	CLIP-seq
MIRT1179013	hsa-miR-4424	CLIP-seq
MIRT1179014	hsa-miR-4428	CLIP-seq
MIRT1179015	hsa-miR-4438	CLIP-seq
MIRT1179016	hsa-miR-4477a	CLIP-seq
MIRT1179017	hsa-miR-4477b	CLIP-seq
MIRT2686094	hsa-miR-4515	CLIP-seq
MIRT2686095	hsa-miR-4652-5p	CLIP-seq
MIRT1179019	hsa-miR-4653-3p	CLIP-seq
MIRT1179020	hsa-miR-4668-3p	CLIP-seq
MIRT2579326	hsa-miR-4682	CLIP-seq
MIRT1179022	hsa-miR-4720-3p	CLIP-seq
MIRT2686096	hsa-miR-4749-3p	CLIP-seq
MIRT2686097	hsa-miR-4786-3p	CLIP-seq
MIRT1179024	hsa-miR-4804-3p	CLIP-seq
MIRT1179025	hsa-miR-5095	CLIP-seq
MIRT2579327	hsa-miR-544b	CLIP-seq
MIRT1179029	hsa-miR-548q	CLIP-seq
MIRT1179030	hsa-miR-580	CLIP-seq
MIRT1179033	hsa-miR-659	CLIP-seq
MIRT2686098	hsa-miR-671-5p	CLIP-seq
MIRT2686099	hsa-miR-9	CLIP-seq

21 Show/Hide all (21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IDA	28844695
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0006120	Process	Mitochondrial electron transport, NADH to ubiquinone	NAS	9878551
GO:0006120	Process	Mitochondrial electron transport, NADH to ubiquinone	TAS	9425316
GO:0008137	Function	NADH dehydrogenase (ubiquinone) activity	NAS	9878551
GO:0008137	Function	NADH dehydrogenase (ubiquinone) activity	TAS	9425316
GO:0009060	Process	Aerobic respiration	NAS	30030361
GO:0016020	Component	Membrane	IEA
GO:0042776	Process	Proton motive force-driven mitochondrial ATP synthesis	NAS	30030361
GO:0045271	Component	Respiratory chain complex I	IBA
GO:0045271	Component	Respiratory chain complex I	IDA	12611891, 27626371
GO:0045271	Component	Respiratory chain complex I	IEA
GO:0045271	Component	Respiratory chain complex I	NAS	9878551
GO:1902600	Process	Proton transmembrane transport	IEA

MIM	HGNC	e!Ensembl
603841	7700	ENSG00000136521

O43674

Protein name

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit)

Protein function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediat

PDB

5XTC , 5XTD , 5XTH , 5XTI

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF09781	NDUF_B5	1 → 189	NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit	Family

Sequence

MAAMSLLRRVSVTAVAALSGRPLGTRLGFGGFLTRGFPKAAAPVRHSGDHGKRLFVIRPS
RFYDRRFLKLLRFYIALTGIPVAIFITLVNVFIGQAELAEIPEGYVPEHWEYYKHPISRW
IARNFYDSPEKIYERTMAVLQIEAEKAELRVKELEVRKLMHVRGDGPWYYYETIDKELID
HSPKATPDN

Sequence length

189

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Oxidative phosphorylation	Respiratory electron transport
Metabolic pathways	Complex I biogenesis
Thermogenesis
Retrograde endocannabinoid signaling
Non-alcoholic fatty liver disease
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Prion disease
Pathways of neurodegeneration - multiple diseases
Chemical carcinogenesis - reactive oxygen species
Diabetic cardiomyopathy

Related Gene	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Names
NDUFA11	[]	10	["Oxidative phosphorylation","Thermogenesis","Retrograde endocannabinoid signaling","Non-alcoholic fatty liver disease","Parkinson disease","Prion disease","Chemical carcinogenesis - reactive oxygen species","Diabetic cardiomyopathy","Respiratory electron transport","Complex I biogenesis"]	[]
NDUFS7	[]	10	["Oxidative phosphorylation","Thermogenesis","Retrograde endocannabinoid signaling","Non-alcoholic fatty liver disease","Parkinson disease","Prion disease","Chemical carcinogenesis - reactive oxygen species","Diabetic cardiomyopathy","Respiratory electron transport","Complex I biogenesis"]	[]
NDUFA1	[]	10	["Oxidative phosphorylation","Thermogenesis","Retrograde endocannabinoid signaling","Non-alcoholic fatty liver disease","Parkinson disease","Prion disease","Chemical carcinogenesis - reactive oxygen species","Diabetic cardiomyopathy","Respiratory electron transport","Complex I biogenesis"]	[]
NDUFA2	[]	10	["Oxidative phosphorylation","Thermogenesis","Retrograde endocannabinoid signaling","Non-alcoholic fatty liver disease","Parkinson disease","Prion disease","Chemical carcinogenesis - reactive oxygen species","Diabetic cardiomyopathy","Respiratory electron transport","Complex I biogenesis"]	[]
NDUFA3	[]	10	["Oxidative phosphorylation","Thermogenesis","Retrograde endocannabinoid signaling","Non-alcoholic fatty liver disease","Parkinson disease","Prion disease","Chemical carcinogenesis - reactive oxygen species","Diabetic cardiomyopathy","Respiratory electron transport","Complex I biogenesis"]	[]

NDUFB5 (NADH:ubiquinone oxidoreductase subunit B5)

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