Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	654816
Gene name	Neutrophil cytosolic factor 1B (pseudogene)
Gene symbol	NCF1B
Synonyms (NCBI Gene)	NCF-1BSH3PXD1B
Chromosome	7
Chromosome location	7q11.23

10 Show/Hide all (10)

GO ID	Ontology	Definition	Evidence
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0016020	Component	Membrane	IEA
GO:0016176	Function	Superoxide-generating NADPH oxidase activator activity	IBA
GO:0016176	Function	Superoxide-generating NADPH oxidase activator activity	IEA
GO:0035091	Function	Phosphatidylinositol binding	IEA
GO:0042554	Process	Superoxide anion generation	IBA
GO:0043020	Component	NADPH oxidase complex	IBA
GO:0045730	Process	Respiratory burst	IBA
GO:0072593	Process	Reactive oxygen species metabolic process	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

A6NI72

Protein name

Putative neutrophil cytosol factor 1B (NCF-1B) (Putative SH3 and PX domain-containing protein 1B)

Protein function

May be required for activation of the latent NADPH oxidase (necessary for superoxide production).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00018	SH3_1	163 → 208	SH3 domain	Domain
PF00018	SH3_1	233 → 278	SH3 domain	Domain
PF00787	PX	31 → 122	PX domain	Domain
PF08944	p47_phox_C	359 → 391	NADPH oxidase subunit p47Phox, C terminal domain	Disordered
PF16621	NECFESHC	283 → 331	SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1	Disordered

Sequence

MGDTFIRHIALLGFEKRFVPSQHYVRYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFP
IEAGAINPENRIIPHLPAPKWFDGQRAAENHQGTLTEYCGTLMSLPTKISRCPHLLDFFK
VRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALST
GDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTA
VEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAP
PRRSSIRNVHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRS
KPQPAVPPRPSADLILNRCSESTKRKLASAV

Sequence length

391

Interactions

View interactions

Related Genes Genes most often co-reported with NCF1B across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for NCF1B.

Diseases Linked via Similar Genes Diseases curated for genes most similar to NCF1B (see Related Genes above), that are NOT already directly curated for NCF1B itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to NCF1B.

NCF1B (neutrophil cytosolic factor 1B (pseudogene))

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