MZT1 (mitotic spindle organizing protein 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 440145 |
| Gene name | Mitotic spindle organizing protein 1 |
| Gene symbol | MZT1 |
| Synonyms (NCBI Gene) |
C13orf37MOZART1
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| Chromosome | 13 |
| Chromosome location | 13q21.33 |
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miRNA
miRNA information provided by mirtarbase database.
301
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q08AG7 | ||||||||||
| Protein name | Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1) | ||||||||||
| Protein function | Required for the recruitment and the assembly of the gamma-tubulin ring complex (gTuRC) at the centrosome (PubMed:20360068, PubMed:38609661, PubMed:39321809). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that g | ||||||||||
| PDB | 6L81 , 6M33 , 6X0U , 7AS4 , 7QJ0 , 7QJ1 , 7QJ2 , 7QJ3 , 7QJ4 , 7QJ5 , 7QJ6 , 7QJ7 , 7QJ8 , 7QJ9 , 7QJA , 7QJB , 7QJC , 7QJD , 8RX1 , 8VRD , 8VRJ , 8VRK | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MASSSGAGAAAAAAAANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEAL |
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| Sequence length | 82 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with MZT1 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to MZT1 (see Related Genes above), that are NOT already directly curated for MZT1 itself -- a lead worth checking, not a confirmed association.
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