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Gene Gene information from NCBI Gene database.
Entrez ID 50804
Gene name Myelin expression factor 2
Gene symbol MYEF2
Synonyms (NCBI Gene)
HsT18564MEF-2MST156MSTP156myEF-2
Chromosome 15
Chromosome location 15q21.1
miRNA miRNA information provided by mirtarbase database.
291 Show/Hide all (291)
miRTarBase ID miRNA Experiments Reference
MIRT029056 hsa-miR-26b-5p Microarray 19088304
MIRT030757 hsa-miR-21-5p Microarray 18591254
MIRT049561 hsa-miR-92a-3p CLASH 23622248
MIRT047609 hsa-miR-10a-5p CLASH 23622248
MIRT045916 hsa-miR-125b-5p CLASH 23622248
Transcription factors Transcription factors information provided by TRRUST V2 database.
2
Transcription factor Regulation Reference
HDAC9 Repression 10487760
MYOG Activation 1656214
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11 Show/Hide all (11)
GO ID Ontology Definition Evidence Reference
GO:0003676 Function Nucleic acid binding IEA
GO:0003677 Function DNA binding IEA
GO:0003723 Function RNA binding HDA 22681889
GO:0003723 Function RNA binding IEA
GO:0003729 Function MRNA binding IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
619395 17940 ENSG00000104177
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9P2K5
Protein name Myelin expression factor 2 (MEF-2) (MyEF-2) (MST156)
Protein function Transcriptional repressor of the myelin basic protein gene (MBP). Binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00076 RRM_1 525 → 593 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 102 → 172 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 235 → 304 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
Sequence
MADANKAEVPGATGGDSPHLQPAEPPGEPRREPHPAEAEKQQPQHSSSSNGVKMENDESA
KEEKSDLKEKSTGSKKANRFHPYSKDKNSGAGEKKGPNRNRVFISNIPYDMKWQAIKDLM
REKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLN
IKEDPDGE
NARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANL
DFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFD
RPMH
VKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLG
PGGMGMDGPGFGGMNRIGGGIGFGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRG
DIGINQGFGDSFGRLGSAMIGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRM
SSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLK
EKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREID
VRLDRNA
Sequence length 600
Interactions View interactions