Log in to bookmark this gene

Bookmark This Gene

Gene Gene information from NCBI Gene database.
Entrez ID 54516
Gene name Mitochondrial translation release factor 1 like
Gene symbol MTRF1L
Synonyms (NCBI Gene)
HMRF1LMRF1LmtRF1a
Chromosome 6
Chromosome location 6q25.2
Summary The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protei
miRNA miRNA information provided by mirtarbase database.
477 Show/Hide all (477)
miRTarBase ID miRNA Experiments Reference
MIRT050842 hsa-miR-17-5p CLASH 23622248
MIRT050099 hsa-miR-26a-5p CLASH 23622248
MIRT048201 hsa-miR-196a-5p CLASH 23622248
MIRT046047 hsa-miR-125b-5p CLASH 23622248
MIRT710179 hsa-miR-508-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17 Show/Hide all (17)
GO ID Ontology Definition Evidence Reference
GO:0003747 Function Translation release factor activity IDA 20075246
GO:0003747 Function Translation release factor activity IEA
GO:0005737 Component Cytoplasm IEA
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
613542 21051 ENSG00000112031
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UGC7
Protein name Peptide chain release factor 1-like, mitochondrial (Mitochondrial translational release factor 1-like) (mtRF1a)
Protein function Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.
PDB 7NQH
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00472 RF-1 228 → 338 RF-1 domain Family
PF03462 PCRF 49 → 221 PCRF domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in skeletal muscle (at protein level). {ECO:0000269|PubMed:17803939}.
Sequence
Sequence length 380
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Mitochondrial translation termination