MT1H (metallothionein 1H)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 4496
• Gene name: Metallothionein 1H
• Gene symbol: MT1H
• Synonyms (NCBI Gene): MT-0, MT-1H, MT-IH, MT1
• Chromosome: 16
• Chromosome location: 16q13

miRNA Show/Hide all (8)

miRTarBase ID	miRNA	Experiments	Reference
MIRT1162126	hsa-miR-23a	CLIP-seq
MIRT1162127	hsa-miR-23b	CLIP-seq
MIRT1162128	hsa-miR-23c	CLIP-seq
MIRT1162129	hsa-miR-27a	CLIP-seq
MIRT1162130	hsa-miR-27b	CLIP-seq
MIRT1162131	hsa-miR-4795-3p	CLIP-seq
MIRT1162132	hsa-miR-513a-5p	CLIP-seq
MIRT1162133	hsa-miR-944	CLIP-seq

Gene ontology (GO) Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	12646258, 12970870, 14668352
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	ISS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	ISS
GO:0006882	Process	Intracellular zinc ion homeostasis	IBA
GO:0008270	Function	Zinc ion binding	ISS
GO:0010273	Process	Detoxification of copper ion	IBA
GO:0045926	Process	Negative regulation of growth	ISS
GO:0046872	Function	Metal ion binding	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0071276	Process	Cellular response to cadmium ion	IBA
GO:0071276	Process	Cellular response to cadmium ion	IEP	16827180
GO:0071280	Process	Cellular response to copper ion	IBA
GO:0071294	Process	Cellular response to zinc ion	IBA
GO:0071294	Process	Cellular response to zinc ion	IEP	8119276, 11168427

Other IDs

• MIM: 156354
• HGNC: 7400
• e!Ensembl: ENSG00000205358

Protein

• UniProt ID: P80294
• Protein name: Metallothionein-1H (MT-1H) (Metallothionein-0) (MT-0) (Metallothionein-IH) (MT-IH)
• Protein function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00131	Metallothio	1 → 61	Metallothionein	Domain

• Sequence:

  MDPNCSCEAGGSCACAGSCKCKKCKCTSCKKSCCSCCPLGCAKCAQGCICKGASEKCSCC
  A

• Sequence length: 61

Pathways

KEGG Pathway:

Mineral absorption

Related Genes

No strongly related genes found yet for MT1H.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MT1H.