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Gene Gene information from NCBI Gene database.
Entrez ID 51154
Gene name MRT4 homolog, ribosome maturation factor
Gene symbol MRTO4
Synonyms (NCBI Gene)
C1orf33MRT4dJ657E11.4
Chromosome 1
Chromosome location 1p36.13
Summary This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq
miRNA miRNA information provided by mirtarbase database.
430 Show/Hide all (430)
miRTarBase ID miRNA Experiments Reference
MIRT027708 hsa-miR-98-5p Microarray 19088304
MIRT045945 hsa-miR-125b-5p CLASH 23622248
MIRT667347 hsa-miR-3158-3p HITS-CLIP 23824327
MIRT667346 hsa-miR-186-3p HITS-CLIP 23824327
MIRT667345 hsa-miR-6878-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12 Show/Hide all (12)
GO ID Ontology Definition Evidence Reference
GO:0000027 Process Ribosomal large subunit assembly IEA
GO:0000956 Process Nuclear-transcribed mRNA catabolic process IBA
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0005515 Function Protein binding IPI 21044950, 35393574
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620476 18477 ENSG00000053372
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UKD2
Protein name mRNA turnover protein 4 homolog (Ribosome assembly factor MRTO4)
Protein function Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
PDB 8FKR , 8FKS , 8FKT , 8FKU , 8FKV , 8FKW , 8FKX , 8FKY , 8FKZ , 8FL0 , 8FL2 , 8FL3 , 8FL4 , 8FL6 , 8FL7 , 8FL9 , 8FLA , 8FLB , 8FLC , 8FLD , 8FLE , 8FLF , 8IDT , 8IDY , 8IE3 , 8INE , 8INF , 8INK , 8IPD , 8IPX , 8IPY , 8IR1 , 8IR3 , 8RL2
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00466 Ribosomal_L10 18 → 121 Ribosomal protein L10 Family
PF17777 RL10P_insert 125 → 195 Insertion domain in 60S ribosomal protein L10P Domain
Sequence
Sequence length 239
Interactions View interactions