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Gene Gene information from NCBI Gene database.
Entrez ID 57380
Gene name Magnesium transporter MRS2
Gene symbol MRS2
Synonyms (NCBI Gene)
HPTMRS2L
Chromosome 6
Chromosome location 6p22.3
miRNA miRNA information provided by mirtarbase database.
324 Show/Hide all (324)
miRTarBase ID miRNA Experiments Reference
MIRT021034 hsa-miR-155-5p Proteomics 18668040
MIRT027867 hsa-miR-98-5p Microarray 19088304
MIRT052486 hsa-let-7a-5p CLASH 23622248
MIRT050531 hsa-miR-20a-5p CLASH 23622248
MIRT037639 hsa-miR-744-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17 Show/Hide all (17)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IDA 11401429
GO:0005739 Component Mitochondrion IEA
GO:0005743 Component Mitochondrial inner membrane IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
619307 13785 ENSG00000124532
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9HD23
Protein name Magnesium transporter MRS2 homolog, mitochondrial (MRS2-like protein)
Protein function Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix and regulates magnesium metabolism (PubMed:11401429, PubMed:18384665, PubMed:37543649, PubMed:37938562, PubMed:39609651). Also permeable to calcium, sodium
PDB 8IP3 , 8IP4 , 8IP5 , 8IP6 , 8TS1 , 8TS2 , 8TS3 , 8TUL , 8TUP
Family and domains
Sequence
MECLRSLPCLLPRAMRLPRRTLCALALDVTSVGPPVAACGRRANLIGRSRAAQLCGPDRL
RVAGEVHRFRTSDVSQATLASVAPVFTVTKFDKQGNVTSFERKKTELYQELGLQARDLRF
QHVMSITVRNNRIIMRMEYLKAVITPECLLILDYRNLNLEQWLFRELPSQLSGEGQLVTY
PLPFEFRAIEALLQYWINTLQGKLSILQPLILETLDALVDPKHSSVDRSKLHILLQNGKS
LSELETDIKIFKESILEILDEEELLEELCVSKWSDPQVFEKSSAGIDHAEEMELLLENYY
RLADDLSNAARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFG
MNLESSLEEDHRIFWLITGIMFMGSGLIWRRLLSFLGRQLEAPLPPMMASLPKKTLLADR
SMELKNSLRLDGLGSGRSILTNR
Sequence length 443
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Miscellaneous transport and binding events