MRS2 (magnesium transporter MRS2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 57380 |
| Gene name | Magnesium transporter MRS2 |
| Gene symbol | MRS2 |
| Synonyms (NCBI Gene) |
HPTMRS2L
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| Chromosome | 6 |
| Chromosome location | 6p22.3 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9HD23 |
| Protein name | Magnesium transporter MRS2 homolog, mitochondrial (MRS2-like protein) |
| Protein function | Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix and regulates magnesium metabolism (PubMed:11401429, PubMed:18384665, PubMed:37543649, PubMed:37938562, PubMed:39609651). Also permeable to calcium, sodium |
| PDB | 8IP3 , 8IP4 , 8IP5 , 8IP6 , 8TS1 , 8TS2 , 8TS3 , 8TUL , 8TUP |
| Family and domains | |
| Sequence |
MECLRSLPCLLPRAMRLPRRTLCALALDVTSVGPPVAACGRRANLIGRSRAAQLCGPDRL |
| Sequence length | 443 |
| Interactions | View interactions |
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with MRS2 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to MRS2 (see Related Genes above), that are NOT already directly curated for MRS2 itself -- a lead worth checking, not a confirmed association.
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