Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	51073
Gene name	Mitochondrial ribosomal protein L4
Gene symbol	MRPL4
Synonyms (NCBI Gene)	CGI-28L4mtuL4m
Chromosome	19
Chromosome location	19p13.2
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016533	hsa-miR-193b-3p	Proteomics	21512034
MIRT016533	hsa-miR-193b-3p	CLASH	23622248
MIRT016533	hsa-miR-193b-3p	CLASH	23622248
MIRT715720	hsa-miR-4496	HITS-CLIP	19536157
MIRT715719	hsa-miR-6729-3p	HITS-CLIP	19536157
MIRT715717	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT715718	hsa-miR-651-5p	HITS-CLIP	19536157
MIRT715720	hsa-miR-4496	HITS-CLIP	19536157
MIRT715719	hsa-miR-6729-3p	HITS-CLIP	19536157
MIRT715717	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT715718	hsa-miR-651-5p	HITS-CLIP	19536157
MIRT1159359	hsa-miR-1234	CLIP-seq
MIRT1159360	hsa-miR-149	CLIP-seq
MIRT1159361	hsa-miR-150	CLIP-seq
MIRT1159362	hsa-miR-24	CLIP-seq
MIRT1159363	hsa-miR-3691-3p	CLIP-seq
MIRT1159364	hsa-miR-4283	CLIP-seq
MIRT1159365	hsa-miR-4284	CLIP-seq
MIRT1159366	hsa-miR-298	CLIP-seq
MIRT1159367	hsa-miR-548ac	CLIP-seq
MIRT1159368	hsa-miR-548ae	CLIP-seq
MIRT1159369	hsa-miR-548aj	CLIP-seq
MIRT1159370	hsa-miR-548am	CLIP-seq
MIRT1159371	hsa-miR-548d-3p	CLIP-seq
MIRT1159372	hsa-miR-548x	CLIP-seq
MIRT1159373	hsa-miR-548z	CLIP-seq
MIRT1159374	hsa-miR-583	CLIP-seq
MIRT1159375	hsa-miR-3199	CLIP-seq
MIRT1159376	hsa-miR-552	CLIP-seq
MIRT1159377	hsa-miR-764	CLIP-seq
MIRT2045703	hsa-miR-1238	CLIP-seq
MIRT2045704	hsa-miR-1268	CLIP-seq
MIRT2045705	hsa-miR-1268b	CLIP-seq
MIRT1159361	hsa-miR-150	CLIP-seq
MIRT2045706	hsa-miR-2467-5p	CLIP-seq
MIRT2045707	hsa-miR-2861	CLIP-seq
MIRT2045708	hsa-miR-3188	CLIP-seq
MIRT2045709	hsa-miR-3667-3p	CLIP-seq
MIRT1159363	hsa-miR-3691-3p	CLIP-seq
MIRT2045710	hsa-miR-3975	CLIP-seq
MIRT2045711	hsa-miR-4649-3p	CLIP-seq
MIRT2045712	hsa-miR-485-5p	CLIP-seq
MIRT2045713	hsa-miR-541	CLIP-seq
MIRT2045714	hsa-miR-544b	CLIP-seq
MIRT2045715	hsa-miR-585	CLIP-seq
MIRT2045716	hsa-miR-654-5p	CLIP-seq
MIRT1159359	hsa-miR-1234	CLIP-seq
MIRT1159360	hsa-miR-149	CLIP-seq
MIRT1159361	hsa-miR-150	CLIP-seq
MIRT1159362	hsa-miR-24	CLIP-seq
MIRT1159363	hsa-miR-3691-3p	CLIP-seq
MIRT1159364	hsa-miR-4283	CLIP-seq
MIRT1159365	hsa-miR-4284	CLIP-seq
MIRT2454468	hsa-miR-3622a-3p	CLIP-seq
MIRT2454469	hsa-miR-3622b-3p	CLIP-seq
MIRT2454470	hsa-miR-370	CLIP-seq
MIRT2454471	hsa-miR-4267	CLIP-seq
MIRT2454472	hsa-miR-628-5p	CLIP-seq
MIRT2454468	hsa-miR-3622a-3p	CLIP-seq
MIRT2454469	hsa-miR-3622b-3p	CLIP-seq
MIRT2454470	hsa-miR-370	CLIP-seq
MIRT2454471	hsa-miR-4267	CLIP-seq
MIRT2454472	hsa-miR-628-5p	CLIP-seq
MIRT2045703	hsa-miR-1238	CLIP-seq
MIRT2045704	hsa-miR-1268	CLIP-seq
MIRT2045705	hsa-miR-1268b	CLIP-seq
MIRT1159361	hsa-miR-150	CLIP-seq
MIRT2045706	hsa-miR-2467-5p	CLIP-seq
MIRT2045707	hsa-miR-2861	CLIP-seq
MIRT2045708	hsa-miR-3188	CLIP-seq
MIRT2045709	hsa-miR-3667-3p	CLIP-seq
MIRT1159363	hsa-miR-3691-3p	CLIP-seq
MIRT2045710	hsa-miR-3975	CLIP-seq
MIRT2045711	hsa-miR-4649-3p	CLIP-seq
MIRT2045712	hsa-miR-485-5p	CLIP-seq
MIRT2045713	hsa-miR-541	CLIP-seq
MIRT2045714	hsa-miR-544b	CLIP-seq
MIRT2045715	hsa-miR-585	CLIP-seq
MIRT2045716	hsa-miR-654-5p	CLIP-seq
MIRT2045703	hsa-miR-1238	CLIP-seq
MIRT2045704	hsa-miR-1268	CLIP-seq
MIRT2045705	hsa-miR-1268b	CLIP-seq
MIRT1159361	hsa-miR-150	CLIP-seq
MIRT2045706	hsa-miR-2467-5p	CLIP-seq
MIRT2045707	hsa-miR-2861	CLIP-seq
MIRT2045708	hsa-miR-3188	CLIP-seq
MIRT2045709	hsa-miR-3667-3p	CLIP-seq
MIRT1159363	hsa-miR-3691-3p	CLIP-seq
MIRT2045710	hsa-miR-3975	CLIP-seq
MIRT2045711	hsa-miR-4649-3p	CLIP-seq
MIRT2045712	hsa-miR-485-5p	CLIP-seq
MIRT2045713	hsa-miR-541	CLIP-seq
MIRT2045714	hsa-miR-544b	CLIP-seq
MIRT2045715	hsa-miR-585	CLIP-seq
MIRT2045716	hsa-miR-654-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003735	Function	Structural constituent of ribosome	IBA
GO:0003735	Function	Structural constituent of ribosome	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 30215512, 32814053
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	28892042
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	NAS	27023846
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0005762	Component	Mitochondrial large ribosomal subunit	IDA	25278503, 28892042
GO:0005762	Component	Mitochondrial large ribosomal subunit	NAS	25278503
GO:0005840	Component	Ribosome	IEA
GO:0006412	Process	Translation	IEA
GO:0032543	Process	Mitochondrial translation	NAS	27023846
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
611823	14276	ENSG00000105364

Q9BYD3

Protein name

Large ribosomal subunit protein uL4m (39S ribosomal protein L4, mitochondrial) (L4mt) (MRP-L4)

PDB

3IY9 , 3J7Y , 3J9M , 5OOL , 5OOM , 6I9R , 6NU2 , 6NU3 , 6VLZ , 6VMI , 6ZM5 , 6ZM6 , 6ZS9 , 6ZSA , 6ZSB , 6ZSC , 6ZSD , 6ZSE , 6ZSG , 7A5F , 7A5G , 7A5H , 7A5I , 7A5J , 7A5K , 7L08 , 7L20 , 7O9K , 7O9M , 7ODR , 7ODS , 7ODT , 7OF0 , 7OF2 , 7OF3 , 7OF4 , 7OF5 , 7OF6 , 7OF7 , 7OG4 , 7OI6 , 7OI7 , 7OI8 , 7OI9 , 7OIA , 7OIB , 7OIC , 7OID , 7OIE , 7PD3 , 7PO4

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00573	Ribosomal_L4	80 → 272	Ribosomal protein L4/L1 family	Family

Sequence

MLQFVRAGARAWLRPTGSQGLSSLAEEAARATENPEQVASEGLPEPVLRKVELPVPTHRR
PVQAWVESLRGFEQERVGLADLHPDVFATAPRLDILHQVAMWQKNFKRISYAKTKTRAEV
RGGGRKPWPQKGTGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTV
KLAQDDLHIMDSLELPTGDPQYLTELAHYRRWGDSVLLVDLTHEEMPQSIVEATSRLKTF
NLIPAVGLNVHSMLKHQTLVLTLPTVAFLEDKLLWQDSRYRPLYPFSLPYSDFPRPLPHA
TQGPAATPYHC

Sequence length

311

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Ribosome	Mitochondrial translation elongation
	Mitochondrial translation termination

MRPL4 (mitochondrial ribosomal protein L4)

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