Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	54948
Gene name	Mitochondrial ribosomal protein L16
Gene symbol	MRPL16
Synonyms (NCBI Gene)	L16mtMRP-L16PNAS-111uL16m
Chromosome	11
Chromosome location	11q12.1
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020738	hsa-miR-155-5p	Proteomics	18668040
MIRT052866	hsa-miR-3622a-3p	CLASH	23622248
MIRT1158435	hsa-miR-1237	CLIP-seq
MIRT1158436	hsa-miR-1248	CLIP-seq
MIRT1158437	hsa-miR-199a-3p	CLIP-seq
MIRT1158438	hsa-miR-199b-3p	CLIP-seq
MIRT1158439	hsa-miR-3129-5p	CLIP-seq
MIRT1158440	hsa-miR-500a	CLIP-seq
MIRT1158441	hsa-miR-582-5p	CLIP-seq
MIRT1158442	hsa-miR-936	CLIP-seq
MIRT1158435	hsa-miR-1237	CLIP-seq
MIRT1158436	hsa-miR-1248	CLIP-seq
MIRT1158437	hsa-miR-199a-3p	CLIP-seq
MIRT1158438	hsa-miR-199b-3p	CLIP-seq
MIRT2045384	hsa-miR-298	CLIP-seq
MIRT1158439	hsa-miR-3129-5p	CLIP-seq
MIRT1158440	hsa-miR-500a	CLIP-seq
MIRT1158441	hsa-miR-582-5p	CLIP-seq
MIRT1158442	hsa-miR-936	CLIP-seq
MIRT1158435	hsa-miR-1237	CLIP-seq
MIRT1158436	hsa-miR-1248	CLIP-seq
MIRT1158437	hsa-miR-199a-3p	CLIP-seq
MIRT1158438	hsa-miR-199b-3p	CLIP-seq
MIRT2045384	hsa-miR-298	CLIP-seq
MIRT1158439	hsa-miR-3129-5p	CLIP-seq
MIRT1158440	hsa-miR-500a	CLIP-seq
MIRT1158441	hsa-miR-582-5p	CLIP-seq
MIRT1158442	hsa-miR-936	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003735	Function	Structural constituent of ribosome	IBA
GO:0003735	Function	Structural constituent of ribosome	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	28892042
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	NAS	27023846
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0005762	Component	Mitochondrial large ribosomal subunit	IBA
GO:0005762	Component	Mitochondrial large ribosomal subunit	IDA	25278503, 28892042
GO:0005762	Component	Mitochondrial large ribosomal subunit	NAS	25278503
GO:0005840	Component	Ribosome	IEA
GO:0006412	Process	Translation	IEA
GO:0015934	Component	Large ribosomal subunit	IEA
GO:0019843	Function	RRNA binding	IBA
GO:0019843	Function	RRNA binding	IEA
GO:0032543	Process	Mitochondrial translation	IBA
GO:0032543	Process	Mitochondrial translation	NAS	27023846
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
611829	14476	ENSG00000166902

Q9NX20

Protein name

Large ribosomal subunit protein uL16m (39S ribosomal protein L16, mitochondrial) (L16mt) (MRP-L16)

PDB

3IY9 , 3J7Y , 3J9M , 5OOL , 5OOM , 6I9R , 6NU2 , 6NU3 , 6VLZ , 6VMI , 6ZM5 , 6ZM6 , 6ZS9 , 6ZSA , 6ZSB , 6ZSC , 6ZSD , 6ZSE , 6ZSG , 7A5F , 7A5G , 7A5H , 7A5I , 7A5J , 7A5K , 7L08 , 7L20 , 7O9K , 7O9M , 7ODR , 7ODS , 7ODT , 7OF0 , 7OF2 , 7OF3 , 7OF4 , 7OF5 , 7OF6 , 7OF7 , 7OG4 , 7OI6 , 7OI7 , 7OI8 , 7OI9 , 7OIA , 7OIB , 7OIC , 7OID , 7OIE , 7PD3 , 7PO4

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00252	Ribosomal_L16	57 → 190	Ribosomal protein L16p/L10e	Family

Sequence

MWRLLARASAPLLRVPLSDSWALLPASAGVKTLLPVPSFEDVSIPEKPKLRFIERAPLVP
KVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFA
IWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVA
HKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGK
YWGKFYMPKRV

Sequence length

251

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Ribosome	Mitochondrial translation elongation
	Mitochondrial translation termination

MRPL16 (mitochondrial ribosomal protein L16)

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