MRGBP (MRG domain binding protein)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 55257
• Gene name: MRG domain binding protein
• Gene symbol: MRGBP
• Synonyms (NCBI Gene): C20orf20, Eaf7, MRG15BP, URCC4
• Chromosome: 20
• Chromosome location: 20q13.33

miRNA Show/Hide all (181)

miRTarBase ID	miRNA	Experiments	Reference
MIRT027304	hsa-miR-101-3p	Sequencing	20371350
MIRT049387	hsa-miR-92a-3p	CLASH	23622248
MIRT041119	hsa-miR-503-5p	CLASH	23622248
MIRT350503	hsa-miR-548ac	PAR-CLIP	20371350
MIRT350511	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT350495	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT350499	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT350502	hsa-miR-548z	PAR-CLIP	20371350
MIRT350504	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT350505	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT350506	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT350507	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT350508	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT350497	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT350501	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT350494	hsa-miR-548a-3p	PAR-CLIP	20371350
MIRT350509	hsa-miR-548ar-3p	PAR-CLIP	20371350
MIRT350510	hsa-miR-548az-3p	PAR-CLIP	20371350
MIRT350496	hsa-miR-548e-3p	PAR-CLIP	20371350
MIRT350498	hsa-miR-548f-3p	PAR-CLIP	20371350
MIRT296661	hsa-miR-5571-5p	PAR-CLIP	20371350
MIRT511160	hsa-miR-3163	PAR-CLIP	20371350
MIRT296655	hsa-miR-3126-3p	PAR-CLIP	20371350
MIRT511159	hsa-miR-1298-3p	PAR-CLIP	20371350
MIRT511158	hsa-miR-1283	PAR-CLIP	20371350
MIRT296656	hsa-miR-3128	PAR-CLIP	20371350
MIRT296663	hsa-miR-6868-5p	PAR-CLIP	20371350
MIRT296659	hsa-miR-4720-5p	PAR-CLIP	20371350
MIRT296660	hsa-miR-4799-3p	PAR-CLIP	20371350
MIRT296662	hsa-miR-5588-5p	PAR-CLIP	20371350
MIRT511157	hsa-miR-4742-3p	PAR-CLIP	20371350
MIRT511156	hsa-miR-187-5p	PAR-CLIP	20371350
MIRT296657	hsa-miR-3191-5p	PAR-CLIP	20371350
MIRT350503	hsa-miR-548ac	PAR-CLIP	21572407
MIRT350511	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT350495	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT350499	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT350502	hsa-miR-548z	PAR-CLIP	21572407
MIRT350504	hsa-miR-548ae-3p	PAR-CLIP	21572407
MIRT350505	hsa-miR-548ah-3p	PAR-CLIP	21572407
MIRT350506	hsa-miR-548aj-3p	PAR-CLIP	21572407
MIRT350507	hsa-miR-548am-3p	PAR-CLIP	21572407
MIRT350508	hsa-miR-548aq-3p	PAR-CLIP	21572407
MIRT350497	hsa-miR-548j-3p	PAR-CLIP	21572407
MIRT350501	hsa-miR-548x-3p	PAR-CLIP	21572407
MIRT350494	hsa-miR-548a-3p	PAR-CLIP	21572407
MIRT350509	hsa-miR-548ar-3p	PAR-CLIP	21572407
MIRT350510	hsa-miR-548az-3p	PAR-CLIP	21572407
MIRT350496	hsa-miR-548e-3p	PAR-CLIP	21572407
MIRT350498	hsa-miR-548f-3p	PAR-CLIP	21572407
MIRT296661	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT511160	hsa-miR-3163	PAR-CLIP	21572407
MIRT296655	hsa-miR-3126-3p	PAR-CLIP	21572407
MIRT511159	hsa-miR-1298-3p	PAR-CLIP	21572407
MIRT511158	hsa-miR-1283	PAR-CLIP	21572407
MIRT296656	hsa-miR-3128	PAR-CLIP	21572407
MIRT296663	hsa-miR-6868-5p	PAR-CLIP	21572407
MIRT296659	hsa-miR-4720-5p	PAR-CLIP	21572407
MIRT296660	hsa-miR-4799-3p	PAR-CLIP	21572407
MIRT296662	hsa-miR-5588-5p	PAR-CLIP	21572407
MIRT511157	hsa-miR-4742-3p	PAR-CLIP	21572407
MIRT296657	hsa-miR-3191-5p	PAR-CLIP	21572407
MIRT350503	hsa-miR-548ac	PAR-CLIP	23446348
MIRT350511	hsa-miR-548bb-3p	PAR-CLIP	23446348
MIRT350495	hsa-miR-548d-3p	PAR-CLIP	23446348
MIRT350499	hsa-miR-548h-3p	PAR-CLIP	23446348
MIRT350502	hsa-miR-548z	PAR-CLIP	23446348
MIRT350504	hsa-miR-548ae-3p	PAR-CLIP	23446348
MIRT350505	hsa-miR-548ah-3p	PAR-CLIP	23446348
MIRT350506	hsa-miR-548aj-3p	PAR-CLIP	23446348
MIRT350507	hsa-miR-548am-3p	PAR-CLIP	23446348
MIRT350508	hsa-miR-548aq-3p	PAR-CLIP	23446348
MIRT350497	hsa-miR-548j-3p	PAR-CLIP	23446348
MIRT350501	hsa-miR-548x-3p	PAR-CLIP	23446348
MIRT350494	hsa-miR-548a-3p	PAR-CLIP	23446348
MIRT350509	hsa-miR-548ar-3p	PAR-CLIP	23446348
MIRT350510	hsa-miR-548az-3p	PAR-CLIP	23446348
MIRT350496	hsa-miR-548e-3p	PAR-CLIP	23446348
MIRT350498	hsa-miR-548f-3p	PAR-CLIP	23446348
MIRT296661	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT511160	hsa-miR-3163	PAR-CLIP	23446348
MIRT296655	hsa-miR-3126-3p	PAR-CLIP	23446348
MIRT511159	hsa-miR-1298-3p	PAR-CLIP	23446348
MIRT511158	hsa-miR-1283	PAR-CLIP	23446348
MIRT296656	hsa-miR-3128	PAR-CLIP	23446348
MIRT296663	hsa-miR-6868-5p	PAR-CLIP	23446348
MIRT296659	hsa-miR-4720-5p	PAR-CLIP	23446348
MIRT296660	hsa-miR-4799-3p	PAR-CLIP	23446348
MIRT296662	hsa-miR-5588-5p	PAR-CLIP	23446348
MIRT511157	hsa-miR-4742-3p	PAR-CLIP	23446348
MIRT511156	hsa-miR-187-5p	PAR-CLIP	23446348
MIRT296657	hsa-miR-3191-5p	PAR-CLIP	23446348
MIRT350503	hsa-miR-548ac	PAR-CLIP	20371350
MIRT350511	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT350495	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT350499	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT350502	hsa-miR-548z	PAR-CLIP	20371350
MIRT350504	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT350505	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT350506	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT350507	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT350508	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT350497	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT350501	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT350494	hsa-miR-548a-3p	PAR-CLIP	20371350
MIRT350509	hsa-miR-548ar-3p	PAR-CLIP	20371350
MIRT350510	hsa-miR-548az-3p	PAR-CLIP	20371350
MIRT350496	hsa-miR-548e-3p	PAR-CLIP	20371350
MIRT350498	hsa-miR-548f-3p	PAR-CLIP	20371350
MIRT296661	hsa-miR-5571-5p	PAR-CLIP	20371350
MIRT511160	hsa-miR-3163	PAR-CLIP	20371350
MIRT296655	hsa-miR-3126-3p	PAR-CLIP	20371350
MIRT511159	hsa-miR-1298-3p	PAR-CLIP	20371350
MIRT511158	hsa-miR-1283	PAR-CLIP	20371350
MIRT296656	hsa-miR-3128	PAR-CLIP	20371350
MIRT296663	hsa-miR-6868-5p	PAR-CLIP	20371350
MIRT296659	hsa-miR-4720-5p	PAR-CLIP	20371350
MIRT296660	hsa-miR-4799-3p	PAR-CLIP	20371350
MIRT296662	hsa-miR-5588-5p	PAR-CLIP	20371350
MIRT511157	hsa-miR-4742-3p	PAR-CLIP	20371350
MIRT511156	hsa-miR-187-5p	PAR-CLIP	20371350
MIRT296657	hsa-miR-3191-5p	PAR-CLIP	20371350
MIRT350503	hsa-miR-548ac	PAR-CLIP	21572407
MIRT350511	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT350495	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT350499	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT350502	hsa-miR-548z	PAR-CLIP	21572407
MIRT350504	hsa-miR-548ae-3p	PAR-CLIP	21572407
MIRT350505	hsa-miR-548ah-3p	PAR-CLIP	21572407
MIRT350506	hsa-miR-548aj-3p	PAR-CLIP	21572407
MIRT350507	hsa-miR-548am-3p	PAR-CLIP	21572407
MIRT350508	hsa-miR-548aq-3p	PAR-CLIP	21572407
MIRT350497	hsa-miR-548j-3p	PAR-CLIP	21572407
MIRT350501	hsa-miR-548x-3p	PAR-CLIP	21572407
MIRT350494	hsa-miR-548a-3p	PAR-CLIP	21572407
MIRT350509	hsa-miR-548ar-3p	PAR-CLIP	21572407
MIRT350510	hsa-miR-548az-3p	PAR-CLIP	21572407
MIRT350496	hsa-miR-548e-3p	PAR-CLIP	21572407
MIRT350498	hsa-miR-548f-3p	PAR-CLIP	21572407
MIRT296661	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT511160	hsa-miR-3163	PAR-CLIP	21572407
MIRT296655	hsa-miR-3126-3p	PAR-CLIP	21572407
MIRT511159	hsa-miR-1298-3p	PAR-CLIP	21572407
MIRT511158	hsa-miR-1283	PAR-CLIP	21572407
MIRT296656	hsa-miR-3128	PAR-CLIP	21572407
MIRT296663	hsa-miR-6868-5p	PAR-CLIP	21572407
MIRT296659	hsa-miR-4720-5p	PAR-CLIP	21572407
MIRT296660	hsa-miR-4799-3p	PAR-CLIP	21572407
MIRT296662	hsa-miR-5588-5p	PAR-CLIP	21572407
MIRT511157	hsa-miR-4742-3p	PAR-CLIP	21572407
MIRT296657	hsa-miR-3191-5p	PAR-CLIP	21572407
MIRT350503	hsa-miR-548ac	PAR-CLIP	23446348
MIRT350511	hsa-miR-548bb-3p	PAR-CLIP	23446348
MIRT350495	hsa-miR-548d-3p	PAR-CLIP	23446348
MIRT350499	hsa-miR-548h-3p	PAR-CLIP	23446348
MIRT350502	hsa-miR-548z	PAR-CLIP	23446348
MIRT350504	hsa-miR-548ae-3p	PAR-CLIP	23446348
MIRT350505	hsa-miR-548ah-3p	PAR-CLIP	23446348
MIRT350506	hsa-miR-548aj-3p	PAR-CLIP	23446348
MIRT350507	hsa-miR-548am-3p	PAR-CLIP	23446348
MIRT350508	hsa-miR-548aq-3p	PAR-CLIP	23446348
MIRT350497	hsa-miR-548j-3p	PAR-CLIP	23446348
MIRT350501	hsa-miR-548x-3p	PAR-CLIP	23446348
MIRT350494	hsa-miR-548a-3p	PAR-CLIP	23446348
MIRT350509	hsa-miR-548ar-3p	PAR-CLIP	23446348
MIRT350510	hsa-miR-548az-3p	PAR-CLIP	23446348
MIRT350496	hsa-miR-548e-3p	PAR-CLIP	23446348
MIRT350498	hsa-miR-548f-3p	PAR-CLIP	23446348
MIRT296661	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT511160	hsa-miR-3163	PAR-CLIP	23446348
MIRT296655	hsa-miR-3126-3p	PAR-CLIP	23446348
MIRT511159	hsa-miR-1298-3p	PAR-CLIP	23446348
MIRT511158	hsa-miR-1283	PAR-CLIP	23446348
MIRT296656	hsa-miR-3128	PAR-CLIP	23446348
MIRT296663	hsa-miR-6868-5p	PAR-CLIP	23446348
MIRT296659	hsa-miR-4720-5p	PAR-CLIP	23446348
MIRT296660	hsa-miR-4799-3p	PAR-CLIP	23446348
MIRT296662	hsa-miR-5588-5p	PAR-CLIP	23446348
MIRT511157	hsa-miR-4742-3p	PAR-CLIP	23446348
MIRT511156	hsa-miR-187-5p	PAR-CLIP	23446348
MIRT296657	hsa-miR-3191-5p	PAR-CLIP	23446348

Gene ontology (GO) Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000786	Component	Nucleosome	IDA	27153538
GO:0005515	Function	Protein binding	IPI	12963728, 15647280, 16230350, 16407074, 24463511, 24981860, 25416956, 25960410, 28514442, 32296183, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006325	Process	Chromatin organization	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0035267	Component	NuA4 histone acetyltransferase complex	IBA
GO:0035267	Component	NuA4 histone acetyltransferase complex	IDA	27153538
GO:0042981	Process	Regulation of apoptotic process	NAS	14966270
GO:0043189	Component	H4/H2A histone acetyltransferase complex	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	NAS	27153538
GO:0051726	Process	Regulation of cell cycle	IMP	27153538
GO:1905168	Process	Positive regulation of double-strand break repair via homologous recombination	IDA	27153538
GO:2000779	Process	Regulation of double-strand break repair	NAS	14966270

Other IDs

• MIM: 611157
• HGNC: 15866
• e!Ensembl: ENSG00000101189

Protein

• UniProt ID: Q9NV56
• Protein name: MRG/MORF4L-binding protein (MRG-binding protein) (Up-regulated in colon cancer 4) (Urcc4)
• Protein function: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA intera
• PDB: 2N1D
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07904	Eaf7	35 → 182	Chromatin modification-related protein EAF7	Family

• Sequence:

  MGEAEVGGGGAAGDKGPGEAATSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICI
  RDKFSQNIGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPEEIIQEVREGKV
  MIEEEMKEEMKEDVDPHNGADDVFSSSGSLGKASEKSSKDKEKNSSDLGCKEGADKRKRS
  RVTDKVLTANSNPSSPSAAKRRRT

• Sequence length: 204

Pathways

KEGG Pathway:

ATP-dependent chromatin remodeling

Related Genes

No strongly related genes found yet for MRGBP.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MRGBP.