MIR424 (microRNA 424) | GeDiPNet

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Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	494336
Gene name	MicroRNA 424
Gene symbol	MIR424
Synonyms (NCBI Gene)	MIR322MIRN424hsa-mir-424miRNA424mir-424
Chromosome	X
Chromosome location	Xq26.3
Summary	microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

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GO ID	Ontology	Definition	Evidence	Reference
GO:0001937	Process	Negative regulation of endothelial cell proliferation	IDA	21885851
GO:0003730	Function	MRNA 3'-UTR binding	IDA	26440600
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0005615	Component	Extracellular space	IDA	25203061
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IGI
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IGI	29130787
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	21885851, 23263626, 23724129, 26440600
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	29130787
GO:0040037	Process	Negative regulation of fibroblast growth factor receptor signaling pathway	IDA	21885851
GO:0040037	Process	Negative regulation of fibroblast growth factor receptor signaling pathway	IGI	23263626
GO:0043537	Process	Negative regulation of blood vessel endothelial cell migration	IGI	23263626
GO:0070317	Process	Negative regulation of G0 to G1 transition	IGI	23263626
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IGI	23263626
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IGI
GO:0106128	Process	Negative regulation of store-operated calcium entry	ISS
GO:1900747	Process	Negative regulation of vascular endothelial growth factor signaling pathway	IDA	21885851
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	21885851, 23263626, 23724129, 26440600, 29130787
GO:1903588	Process	Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	21885851
GO:1904706	Process	Negative regulation of vascular associated smooth muscle cell proliferation	IGI	23263626
GO:1904706	Process	Negative regulation of vascular associated smooth muscle cell proliferation	ISS
GO:1904753	Process	Negative regulation of vascular associated smooth muscle cell migration	ISS
GO:1904831	Process	Positive regulation of aortic smooth muscle cell differentiation	ISS
GO:1905563	Process	Negative regulation of vascular endothelial cell proliferation	IGI	23263626
GO:2000545	Process	Negative regulation of endothelial cell chemotaxis to fibroblast growth factor	IDA	21885851
GO:2001027	Process	Negative regulation of endothelial cell chemotaxis	IDA	21885851

MIM	HGNC	e!Ensembl
300682	31881	ENSG00000284231

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