MIR29B1 (microRNA 29b-1)

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Gene Gene ontology Other IDs Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 407024
• Gene name: MicroRNA 29b-1
• Gene symbol: MIR29B1
• Synonyms (NCBI Gene): MIRN29B1, miR-29b, miRNA29B1, mir-29b-1
• Chromosome: 7
• Chromosome location: 7q32.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO) Show/Hide all (66)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001960	Process	Negative regulation of cytokine-mediated signaling pathway	IDA	23729669
GO:0003730	Function	MRNA 3'-UTR binding	IDA	18434550, 23729669, 31553627
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0005634	Component	Nucleus	IDA	17204650
GO:0005737	Component	Cytoplasm	IDA	17204650
GO:0005739	Component	Mitochondrion	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	19850741, 24091622, 24130168, 25032858, 25784815
GO:0010628	Process	Positive regulation of gene expression	IDA	19956414
GO:0010628	Process	Positive regulation of gene expression	IGI	22269326
GO:0010629	Process	Negative regulation of gene expression	IDA	23729669
GO:0010629	Process	Negative regulation of gene expression	IDA	19956414, 20570858, 25032858
GO:0010629	Process	Negative regulation of gene expression	IMP	27030318
GO:0010716	Process	Negative regulation of extracellular matrix disassembly	ISS
GO:0010719	Process	Negative regulation of epithelial to mesenchymal transition	IDA	25032858
GO:0010867	Process	Positive regulation of triglyceride biosynthetic process	ISS
GO:0016442	Component	RISC complex	IEA
GO:0030335	Process	Positive regulation of cell migration	IDA	25435433
GO:0030336	Process	Negative regulation of cell migration	IDA	24091622, 24130168, 25032858, 25428377, 25784815
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IDA	26687115
GO:0032966	Process	Negative regulation of collagen biosynthetic process	IDA	19913496, 23221517
GO:0032966	Process	Negative regulation of collagen biosynthetic process	IGI	22269326
GO:0034345	Process	Negative regulation of type III interferon production	IDA	23729669
GO:0035021	Process	Negative regulation of Rac protein signal transduction	IDA	25032858
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	18434550, 19850741, 19913496, 19956414, 20041405, 20086245, 20479936, 20570858, 20657750, 22745231, 23221517, 23729669, 23857059, 24091622, 24130168, 24578160, 25032858, 25428377, 25435433, 25744716, 25784815, 26687115, 26820803, 27089893, 27812842, 31553627, 31694982
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IGI	22269326
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	27030318
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	17404574, 20657750
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	26175849
GO:0040029	Process	Epigenetic regulation of gene expression	IDA	23857059
GO:0043065	Process	Positive regulation of apoptotic process	IDA	19850741, 20041405, 24130168, 25784815
GO:0043065	Process	Positive regulation of apoptotic process	IMP	17404574
GO:0045600	Process	Positive regulation of fat cell differentiation	IMP	27030318
GO:0045669	Process	Positive regulation of osteoblast differentiation	ISS
GO:0050680	Process	Negative regulation of epithelial cell proliferation	ISS
GO:0050709	Process	Negative regulation of protein secretion	ISS
GO:0051898	Process	Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA	25428377
GO:0060306	Process	Regulation of membrane repolarization	IDA	31553627
GO:0060312	Process	Regulation of blood vessel remodeling	NAS	22269326
GO:0061754	Process	Negative regulation of circulating fibrinogen levels	IDA	20570858
GO:0070062	Component	Extracellular exosome	IDA	28159509
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IDA	26687115
GO:0090263	Process	Positive regulation of canonical Wnt signaling pathway	ISS
GO:0098586	Process	Cellular response to virus	IMP	23729669
GO:0106222	Function	LncRNA binding	IDA	31694982
GO:0150190	Process	Negative regulation of interleukin-32 production	IDA	23729669
GO:1901202	Process	Negative regulation of extracellular matrix assembly	NAS	22269326
GO:1901223	Process	Negative regulation of non-canonical NF-kappaB signal transduction	IDA	26687115
GO:1901380	Process	Negative regulation of potassium ion transmembrane transport	IDA	31553627
GO:1902110	Process	Positive regulation of mitochondrial membrane permeability involved in apoptotic process	IDA	20041405
GO:1902176	Process	Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	IDA	19956414
GO:1902430	Process	Negative regulation of amyloid-beta formation	IDA	18434550
GO:1902461	Process	Negative regulation of mesenchymal stem cell proliferation	IMP	27030318
GO:1902992	Process	Negative regulation of amyloid precursor protein catabolic process	IDA	18434550
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	17404574, 18434550, 19850741, 19913496, 19956414, 20041405, 20479936, 20657750, 22745231, 23221517, 23729669, 23857059, 24091622, 24130168, 24578160, 25032858, 25428377, 25435433, 25744716, 25784815, 26175849, 26687115, 26820803, 27089893, 27812842, 31553627, 31694982
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	27030318
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903845	Process	Negative regulation of cellular response to transforming growth factor beta stimulus	IGI	22269326
GO:1903847	Process	Regulation of aorta morphogenesis	ISS
GO:1904027	Process	Negative regulation of collagen fibril organization	ISS
GO:1904465	Process	Negative regulation of matrix metallopeptidase secretion	ISS
GO:1905041	Process	Regulation of epithelium regeneration	IDA	23221517
GO:1905299	Process	Negative regulation of intestinal epithelial cell development	ISS
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IDA	24130168, 25784815
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IMP	27030318
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	ISS

Other IDs

• MIM: 610783
• HGNC: 31619
• e!Ensembl: ENSG00000283797

Interactions View interactions

Pathways

KEGG Pathway

MicroRNAs in cancer

Chemical carcinogenesis - receptor activation

Related Genes

No strongly related genes found yet for MIR29B1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MIR29B1.