MIR26A1 (microRNA 26a-1)

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Gene Gene ontology Other IDs Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 407015
• Gene name: MicroRNA 26a-1
• Gene symbol: MIR26A1
• Synonyms (NCBI Gene): MIR26A, MIRN26A1, mir-26a-1
• Chromosome: 3
• Chromosome location: 3p22.2
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO) Show/Hide all (35)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	22484120
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0005615	Component	Extracellular space	IDA	25203061
GO:0007179	Process	Transforming growth factor beta receptor signaling pathway	IDA	20857419
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	18713946, 23389848
GO:0010459	Process	Negative regulation of heart rate	ISS
GO:0016442	Component	RISC complex	IEA
GO:0030336	Process	Negative regulation of cell migration	IDA	23389848
GO:0030514	Process	Negative regulation of BMP signaling pathway	IDA	24047927
GO:0032286	Process	Central nervous system myelin maintenance	ISS	25362566
GO:0032700	Process	Negative regulation of interleukin-17 production	ISS	25362566
GO:0032715	Process	Negative regulation of interleukin-6 production	IDA	27252421
GO:0032715	Process	Negative regulation of interleukin-6 production	IDA	27252421, 30542439
GO:0032715	Process	Negative regulation of interleukin-6 production	ISS	25362566
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	18713946, 20660482, 20857419, 22484120, 22673513, 23389848, 23543060, 24047927, 25362566, 25613580, 27252421, 28602162, 30542439
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0038084	Process	Vascular endothelial growth factor signaling pathway	IDA	28602162
GO:0043409	Process	Negative regulation of MAPK cascade	IDA	25613580
GO:0060371	Process	Regulation of atrial cardiac muscle cell membrane depolarization	IMP	23543060
GO:0060392	Process	Negative regulation of SMAD protein signal transduction	IDA	24047927
GO:0070104	Process	Negative regulation of interleukin-6-mediated signaling pathway	IDA	23389848
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IDA	24047927, 25613580, 28602162
GO:0090263	Process	Positive regulation of canonical Wnt signaling pathway	IDA	22484120
GO:0090370	Process	Negative regulation of cholesterol efflux	ISS	22673513
GO:0150079	Process	Negative regulation of neuroinflammatory response	ISS	25362566
GO:1900016	Process	Negative regulation of cytokine production involved in inflammatory response	IDA	27252421
GO:1902807	Process	Negative regulation of cell cycle G1/S phase transition	IDA	18713946
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	18713946, 20660482, 22484120, 22673513, 23389848, 23543060, 24047927, 25362566, 25613580, 27252421, 28602162, 30542439
GO:1903287	Process	Negative regulation of potassium ion import across plasma membrane	IMP	23543060
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903588	Process	Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	25613580, 28602162
GO:1904707	Process	Positive regulation of vascular associated smooth muscle cell proliferation	IMP	20857419
GO:1904754	Process	Positive regulation of vascular associated smooth muscle cell migration	IMP	20857419
GO:1905064	Process	Negative regulation of vascular associated smooth muscle cell differentiation	IDA	20857419
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IDA	23389848, 24047927

Other IDs

• MIM: 612151
• HGNC: 31610
• e!Ensembl: ENSG00000199075

Interactions View interactions

Pathways

KEGG Pathway:

MicroRNAs in cancer

Related Genes

No strongly related genes found yet for MIR26A1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MIR26A1.