MIR214 (microRNA 214) | Gene Details, Disease Associations & Pathways | GeDiPNet

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Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	406996
Gene name	MicroRNA 214
Gene symbol	MIR214
Synonyms (NCBI Gene)	MIRN214miRNA214mir-214
Chromosome	1
Chromosome location	1q24.3
Summary	microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	30703347
GO:0005634	Component	Nucleus	IDA	24158985
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	25656649
GO:0010593	Process	Negative regulation of lamellipodium assembly	ISS
GO:0010629	Process	Negative regulation of gene expression	IDA	27144530
GO:0010629	Process	Negative regulation of gene expression	IMP	30703347
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IDA	25656649
GO:0016525	Process	Negative regulation of angiogenesis	ISS
GO:0030336	Process	Negative regulation of cell migration	IDA	25656649
GO:0030514	Process	Negative regulation of BMP signaling pathway	IMP	30703347
GO:0030837	Process	Negative regulation of actin filament polymerization	ISS
GO:0032682	Process	Negative regulation of chemokine production	IDA	30703347
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	24011070, 25656649, 25910754, 27144530, 28684904
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	23238222
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	22336710
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	30703347
GO:0045668	Process	Negative regulation of osteoblast differentiation	IMP	30703347
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	24158985
GO:0060546	Process	Negative regulation of necroptotic process	IDA	25910754
GO:0071456	Process	Cellular response to hypoxia	IDA	27144530
GO:1900087	Process	Positive regulation of G1/S transition of mitotic cell cycle	IDA	27144530
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	22336710, 24011070, 25656649, 25910754, 27144530, 28684904, 30703347
GO:1903243	Process	Negative regulation of cardiac muscle hypertrophy in response to stress	ISS	27162619
GO:1903244	Process	Positive regulation of cardiac muscle hypertrophy in response to stress	ISS
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1904706	Process	Negative regulation of vascular associated smooth muscle cell proliferation	IMP	27927633
GO:1904707	Process	Positive regulation of vascular associated smooth muscle cell proliferation	IDA	27144530, 28684904
GO:1904753	Process	Negative regulation of vascular associated smooth muscle cell migration	IMP	27927633
GO:1905176	Process	Positive regulation of vascular associated smooth muscle cell dedifferentiation	IDA	27144530
GO:1905205	Process	Positive regulation of connective tissue replacement	ISS

MIM	HGNC	e!Ensembl
610721	31591	ENSG00000283844

Interactions View interactions

KEGG Pathway
MicroRNAs in cancer