MIR20A (microRNA 20a)

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Gene Gene ontology Other IDs Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 406982
• Gene name: MicroRNA 20a
• Gene symbol: MIR20A
• Synonyms (NCBI Gene): C13orf25, MIR17HG, MIR20, MIRH1, MIRHG1, MIRN20, MIRN20A, hsa-mir-20, hsa-mir-20a, miR-20, miRNA20A, mir-20a
• Chromosome: 13
• Chromosome location: 13q31.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO) Show/Hide all (50)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001960	Process	Negative regulation of cytokine-mediated signaling pathway	IDA	28972028
GO:0003151	Process	Outflow tract morphogenesis	ISS
GO:0003730	Function	MRNA 3'-UTR binding	IDA	21743293, 21982160, 22785209, 24378993
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0006954	Process	Inflammatory response	IDA	29653364
GO:0010611	Process	Regulation of cardiac muscle hypertrophy	ISS
GO:0010629	Process	Negative regulation of gene expression	IGI	22450430
GO:0010629	Process	Negative regulation of gene expression	IMP	22450430
GO:0010667	Process	Negative regulation of cardiac muscle cell apoptotic process	ISS
GO:0016442	Component	RISC complex	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IDA	21145484
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IGI	31368162
GO:0030513	Process	Positive regulation of BMP signaling pathway	IDA	21743293
GO:0030514	Process	Negative regulation of BMP signaling pathway	IGI	22450430
GO:0032700	Process	Negative regulation of interleukin-17 production	IDA	28972028
GO:0034144	Process	Negative regulation of toll-like receptor 4 signaling pathway	IDA	29653364
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	HDA	18320040
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	17205120, 20190813, 20583868, 21067317, 21743293, 21982160, 22696064, 22785209, 23059786, 23285084, 23308108, 23969726, 24378993, 25447536, 28097093, 28972028
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	22450430
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	23562609
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IMP	19390056
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	29653364, 31368162
GO:0035924	Process	Cellular response to vascular endothelial growth factor stimulus	IDA	22696064
GO:0042985	Process	Negative regulation of amyloid precursor protein biosynthetic process	IDA	21982160
GO:0045669	Process	Positive regulation of osteoblast differentiation	IDA	21743293
GO:0045766	Process	Positive regulation of angiogenesis	IDA	28097093
GO:0050728	Process	Negative regulation of inflammatory response	IDA	28972028
GO:0050766	Process	Positive regulation of phagocytosis	ISS
GO:0051497	Process	Negative regulation of stress fiber assembly	IDA	22696064
GO:0051898	Process	Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA	28972028
GO:0060354	Process	Negative regulation of cell adhesion molecule production	IMP	22785209
GO:0070100	Process	Negative regulation of chemokine-mediated signaling pathway	IDA	28972028
GO:0071222	Process	Cellular response to lipopolysaccharide	ISS
GO:0071456	Process	Cellular response to hypoxia	IDA	31368162
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IDA	22696064
GO:0140052	Process	Cellular response to oxidised low-density lipoprotein particle stimulus	IDA	29653364
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	HDA	18320040
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	17205120, 20190813, 20583868, 21067317, 21743293, 21982160, 22696064, 22785209, 23059786, 23285084, 23308108, 23562609, 23969726, 24378993, 28097093, 28972028, 29653364, 31368162
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IGI	21145484
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	19390056
GO:1903244	Process	Positive regulation of cardiac muscle hypertrophy in response to stress	ISS
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903671	Process	Negative regulation of sprouting angiogenesis	IDA	20299512
GO:1903753	Process	Negative regulation of p38MAPK cascade	IDA	22696064
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	HMP	18320040
GO:1904707	Process	Positive regulation of vascular associated smooth muscle cell proliferation	IDA	22450430, 25447536
GO:1904754	Process	Positive regulation of vascular associated smooth muscle cell migration	IDA	25447536
GO:1905061	Process	Negative regulation of cardioblast proliferation	ISS
GO:1905111	Process	Positive regulation of pulmonary blood vessel remodeling	ISS

Other IDs

• MIM: 609420
• HGNC: 31577
• e!Ensembl: ENSG00000283762

Interactions View interactions

Pathways

KEGG Pathway:

MicroRNAs in cancer

Related Genes

No strongly related genes found yet for MIR20A.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MIR20A.