MIR19B1 (microRNA 19b-1)

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Gene Gene ontology Other IDs Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 406980
• Gene name: MicroRNA 19b-1
• Gene symbol: MIR19B1
• Synonyms (NCBI Gene): C13orf25, MIR17HG, MIR19B, MIRH1, MIRHG1, MIRN19B1, miR-19b-1, miRNA19B1
• Chromosome: 13
• Chromosome location: 13q31.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO) Show/Hide all (38)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002862	Process	Negative regulation of inflammatory response to antigenic stimulus	IDA	22105995
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0008284	Process	Positive regulation of cell population proliferation	ISS
GO:0010629	Process	Negative regulation of gene expression	IDA	25765596
GO:0010667	Process	Negative regulation of cardiac muscle cell apoptotic process	ISS
GO:0010764	Process	Negative regulation of fibroblast migration	IDA	27098600
GO:0010972	Process	Negative regulation of G2/M transition of mitotic cell cycle	IDA	22197821
GO:0016442	Component	RISC complex	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IDA	27098600
GO:0032715	Process	Negative regulation of interleukin-6 production	IDA	22105995
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	18728182, 22197821, 23271053, 24998411, 25084135, 28969074
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	21796614, 22105995
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	27098600
GO:0042632	Process	Cholesterol homeostasis	IDA	25084135, 25765596
GO:0048471	Component	Perinuclear region of cytoplasm	ISS
GO:0050819	Process	Negative regulation of coagulation	IDA	24998411
GO:0060045	Process	Positive regulation of cardiac muscle cell proliferation	ISS
GO:0060923	Process	Cardiac muscle cell fate commitment	ISS
GO:0061051	Process	Positive regulation of cell growth involved in cardiac muscle cell development	IGI	24117217
GO:0061051	Process	Positive regulation of cell growth involved in cardiac muscle cell development	ISS
GO:0062044	Process	Negative regulation of cardiac epithelial to mesenchymal transition	IDA	27098600
GO:0071221	Process	Cellular response to bacterial lipopeptide	IDA	22105995
GO:0072562	Component	Blood microparticle	IDA	24998411
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IDA	22197821
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	ISS
GO:0090370	Process	Negative regulation of cholesterol efflux	IDA	25084135
GO:0090370	Process	Negative regulation of cholesterol efflux	IMP	25765596
GO:0097006	Process	Regulation of plasma lipoprotein particle levels	ISS
GO:1901202	Process	Negative regulation of extracellular matrix assembly	IDA	27098600
GO:1903063	Process	Negative regulation of reverse cholesterol transport	ISS
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	18728182, 21796614, 23271053, 24998411, 25084135, 27098600, 28969074
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	22105995
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903845	Process	Negative regulation of cellular response to transforming growth factor beta stimulus	IDA	27098600
GO:1904465	Process	Negative regulation of matrix metallopeptidase secretion	IDA	22105995
GO:1904747	Process	Positive regulation of apoptotic process involved in development	ISS
GO:1905095	Process	Negative regulation of apolipoprotein A-I-mediated signaling pathway	IDA	25084135

Other IDs

• MIM: 609419
• HGNC: 31575
• e!Ensembl: ENSG00000284375

Interactions View interactions

Pathways

KEGG Pathway:

MicroRNAs in cancer

Related Genes

No strongly related genes found yet for MIR19B1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MIR19B1.